MyMedR

Fulltext What it takes to set up travel health services: a review from countries with established service

Muhammad Haikal Ghazali, Shamsul Azhar Shah, Mohd Rizal Abd Manaf

Malaysian Journal of Public Health Medicine, 2017;17(2):47-57.

As air travelling now becomes cheaper and available to almost all people of any walk of life, travelling across international borders is fast becoming a lifestyle of many. Having travel health service as part of health care services is important to address the issues of travel related illnesses among travellers. However, lacks of published guidelines pertaining to travel health service rendering many countries to overlook its importance. The aim of this paper is to review published literatures and authoritative websites on the components needed to develop guideline to establish travel health services. A systematic literature search was done using pre-specified keywords for literatures published between years 2000 – 2016. Literatures written in English and fully accessible were all included. No exclusion criteria was set before the search. Online authoritative websites pertaining to travel health were also referred. A total of six literatures ranging from expert opinion, review paper and original study, together with three authoritative websites related to travel health were reviewed. Among the important components needed to be considered for developing the guideline for establishing travel health services are to prioritise pre-travel health service, to set up specialised travel health clinic, to produce travel health/medicine specialist, to emphasize on continuous education and training of the practitioners and to apply multiagency and multidisciplinary approach with adequate fund for research in travel health. As a conclusion, policy makers should prioritise and select the most important components in developing guideline for travel health service.

A critical view on the analysis of fluorescence quenching data for determining ligand-protein binding affinity

Bakar KA, Feroz SR

Spectrochim Acta A Mol Biomol Spectrosc, 2019 Dec 05;223:117337.

PMID: 31302564 DOI: 10.1016/j.saa.2019.117337

The past decade has seen an increase in the number of research papers on ligand binding to proteins based on fluorescence spectroscopy. In most cases, determination of the binding affinity is made by analyzing the quenching of protein fluorescence induced by the ligand. However, many such articles, even those published in reputed journals, suffer from several mistakes with regard to analysis of fluorescence quenching data. Using the binding of phenylbutazone to human serum albumin as a model, we consider some of these mistakes and show how they affect the values of the association constant. In particular, the failure to correct for the inner filter effect and the use of unsuitable equations are discussed. Ligand binding data presented in these articles should be treated with caution, especially in the absence of data from complementary techniques.

Fulltext Experimental and numerical analysis of pGFRP and wood cross-arm in latticed tower: a comprehensive study of mechanical deformation and flexural creep

Latif AA, Ishak MR, Razman MR, Yidris N, Mohd Zuhri MY, Rizal MAM, et al.

Sci Rep, 2025 Jan 09;15(1):1432.

PMID: 39789006 DOI: 10.1038/s41598-024-83634-7

The adoption of pultruded glass fibre-reinforced polymer (pGFRP) composites as a substitute for traditional wooden cross-arms in high transmission towers represents a relatively novel approach. These materials were selected for their high strength-to-weight ratio and lightweight properties. Despite various studies focusing on structures improvement, there still have a significant gap in understanding the deformation characteristics of full-scale cross-arms under actual operational loads. Existing study often concentrate on small coupon scale and laboratory condition, leaving a gap in understanding how the cross-arm behavior in full-scale acting on actual weather condition. This study aims to investigate the load-deflection and long-term creep behavior of a pGFRP cross-arm installed in a 132 kV transmission tower. The pGFRP cross-arm was load-tested on a customized rig in an open environment. Using the cantilever beam concept, deflection was analyzed and compared to wood cross-arms. Finite element analysis validated results, and long-term deformation under high-stress loads was assessed. The pGFRP cross-arms showed lower deflection at working loads compared to Balau wood, due to the latter's higher elastic modulus and flexibility specifically at Point Y3, the critical issues necessitated reinforcement strategies. pGFRP cross-arms withstood higher bending stress, showing 32% less deflection under normal conditions and 15% less under broken wire conditions than Balau wood. Additionally, the creep strength of wood was 34% lower than that of pGFRP cross-arms. Besides that, the pGFRP cross-arm have highest elastic modulus than Balau-wood, shows that the composite cross-arm have better structural strength, resisting deformation and higher flexibility materials. Finite element analysis (FEA) confirmed these results with the relative error between them less than 1%. Consequently, the investigation into pGFRP cross-arm deformation behavior in this paper serves as a foundational framework for future research endeavors specifically for high transmission tower and other structural application.

Fulltext Evaluation of psychometric properties of the malay version perceived stress scale in two occupational settings in malaysia

Al-Dubai S, Ganasegeran K, Barua A, Rizal A, Rampal K

Ann Med Health Sci Res, 2014 Jul;4(Suppl 2):S104-7.

PMID: 25184074 DOI: 10.4103/2141-9248.138023

BACKGROUND: The 10-item version of Perceived Stress Scale (PSS-10) is a widely used tool to measure stress. The Malay version of the PSS-10 has been validated among Malaysian Medical Students. However, studies have not been conducted to assess its validity in occupational settings.
AIM: The aim of this study is to assess the psychometric properties of the Malay version of the PSS-10 in two occupational setting in Malaysia.
SUBJECTS AND METHODS: This study was conducted among 191 medical residents and 513 railway workers. An exploratory factor analysis was performed using the principal component method with varimax rotation. Correlation analyses, Kaiser-Meyer-Olkin, Bartlett's test of Sphericity and Cronbach's alpha were obtained. Statistical analysis was carried out using statistical package for the social sciences version 16 (SPSS, Chicago, IL, USA) software.
RESULTS: Analysis yielded two factor structure of the Malay version of PSS-10 in both occupational groups. The two factors accounted for 59.2% and 64.8% of the variance in the medical residents and the railway workers respectively. Factor loadings were greater than 0.59 in both occupational groups. Cronbach's alpha co-efficient was 0.70 for medical residents and 0.71 for railway workers.
CONCLUSION: The Malay version of PSS-10 had adequate psychometric properties and can be used to measure stress among occupational settings in Malaysia.
KEYWORDS: Factor structure; Malaysia; Occupational; Perceived stress scale; Psychometric properties; Validity

Fulltext Bis{2-[2-(1H-indol-3-yl)ethyl-imino-meth-yl]phenolato-κN,O}nickel(II) N,N-dimethyl-formamide disolvate

Ali HM, Mohamed Mustafa MI, Rizal MR, Ng SW

Acta Crystallogr Sect E Struct Rep Online, 2008;64(Pt 6):m787.

PMID: 21202476 DOI: 10.1107/S1600536808012968

The Ni atom in the title compound, [Ni(C(17)H(15)N(2)O)(2)]·2C(3)H(7)NO, lies on a twofold rotation axis. It is N,O-chelated by the deprotonated Schiff base 2-[2-(1H-indol-3-yl)ethyl-imino-meth-yl]phenolate ligand in a square-planar coordination environment. The mol-ecule is linked to a solvent mol-ecule by an indole-dimethyl-formamide N-H⋯O hydrogen bond.

Fulltext 2-[2-(1H-indol-3-yl)ethyl-iminiomethyl]-4-nitro-phenolate

Ali HM, Mohamed Mustafa MI, Rizal MR, Ng SW

Acta Crystallogr Sect E Struct Rep Online, 2008;64(Pt 5):o913.

PMID: 21202395 DOI: 10.1107/S1600536808011185

The title Schiff base, C(17)H(15)N(3)O(3), exists in the zwitterionic form with the phenol H atom transferred to the imine group. Adjacent zwitterions are linked into a linear chain running along the a axis by an indole-hydr-oxy N-H⋯O hydrogen bond [3.100 (2) Å].

Fulltext N'-(5-Fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl-idene)benzene-sulfono-hydrazide

Ali HM, Laila M, Rizal MR, Ng SW

Acta Crystallogr Sect E Struct Rep Online, 2008;64(Pt 5):o921.

PMID: 21202402 DOI: 10.1107/S1600536808011136

The mol-ecule of the title compound, C(14)H(10)FN(3)O(3)S, consists of an indole unit and a phenylsulfonyl unit that are disposed in an approximately trans orientation relative to the N-N single bond. Two mol-ecules are arranged about a center of inversion, forming a hydrazide-carbonyl N-H⋯O hydrogen-bonded dimer; the dimers are linked by an indole-sulfonyl N-H⋯O hydrogen bond into a ribbon.

Fulltext The electroencephalogram changes in migraineurs

Tan HJ, Suganthi C, Dhachayani S, Rizal AM, Raymond AA

Med J Malaysia, 2007 Mar;62(1):56-8.

PMID: 17682573 MyJurnal

Migraine is associated with a variety of electroencephalographic (EEG) changes. Previous studies using analogue EEG and old diagnostic criteria may under or over report the prevalence of EEG changes in migraine. The objective of this study was to reevaluate the EEG changes in migraine patients diagnosed by applying the new International Classification of Headache Disorder -2 criteria. This was a case control study involving 70 migraine patients and 70 age and gender matched control who were subjected to scalp EEG. The EEG changes during hyperventilation (HV), which were significantly more common in the migraine group were theta activity (34 vs 22, p = 0.038) and frontal intermittent rhythmic delta activity (FIRDA) (10 vs 3, p = 0.042). Applying the new ICHD -2 diagnostic criteria and digital EEG, this study yielded previously unrecognized features including FIRDA during HV on EEG.

Fulltext Bis{μ-N'-[1-(5-bromo-2-oxidophen-yl)ethyl-idene]benzene-sulfono-hydrazidato}-κO,N':N;κN:O,N'-bis-[(dimethyl sulfoxide-κO)copper(II)]

Ali HM, Laila M, Rizal RM, Ng SW

Acta Crystallogr Sect E Struct Rep Online, 2008;64(Pt 2):m414.

PMID: 21201360 DOI: 10.1107/S1600536808002201

In the title centrosymmetric dinuclear complex, [Cu(2)(C(15)H(11)BrN(2)O(3)S)(2)(C(2)H(6)OS)(2)], the Cu(II) ion is N,O-chelated by a dianionic ligand, monocoordinated by the sulfonamide N atom of a symmetry-related ligand and coordinated by an O atom from a dimethyl sulfoxide ligand, forming a distorted square-planar coordination geometry.

Fulltext N'-(2,5-Dihydroxy-benzyl-idene)benzene-sulfonohydrazide

Ali HM, Yusnita J, Rizal MR, Ng SW

Acta Crystallogr Sect E Struct Rep Online, 2008;64(Pt 2):o522.

PMID: 21201541 DOI: 10.1107/S1600536808002225

In the title compound, C(13)H(12)N(2)O(4)S, the dihedral angle between the two aromatic rings is 89.5 (1)°. In the crystal structure, mol-ecules are linked by O-H⋯O(hydr-oxy) and N-H⋯O(sulfon-yl) hydrogen bonds, forming a ribbon that propagates along the b axis; there is also an intra-molecular O-H⋯N hydrogen bond.

Fulltext Bis{4-chloro-2-[2-(1H-indol-3-yl)ethyl-imino-meth-yl]phenolato-κN,O}zinc(II)

Ali HM, Mohamed Mustafa MI, Rizal MR, Ng SW

Acta Crystallogr Sect E Struct Rep Online, 2008;64(Pt 2):m421.

PMID: 21201365 DOI: 10.1107/S1600536808002213

The Zn atom in the title compound, [Zn(C(17)H(14)ClN(2)O)(2)], is N,O-chelated by two deprotonated Schiff base monoanionic ligands in a tetra-hedral coordination geometry. The Zn atom lies on a special position of site symmetry 2.

Fulltext Dichloridobis(2-{1-[2-(1H-indol-3-yl)ethyl-iminio]eth-yl}phenolate-κO)zinc(II)-2-{1-[2-(1H-indol-3-yl)ethyl-iminio]eth-yl}phenolate (1/2)

Ali HM, Mohamed Mustafa MI, Rizal MR, Ng SW

Acta Crystallogr Sect E Struct Rep Online, 2008;64(Pt 5):m718-9.

PMID: 21202245 DOI: 10.1107/S1600536808011161

In the mononuclear complex mol-ecule of the title compond, [ZnCl(2)(C(18)H(18)N(2)O)(2)]·2C(18)H(18)N(2)O, the Zn atom, which lies on a twofold rotation axis, is coordinated by phenolate O atoms in a tetra-hedral coordination geometry. The coordinated Schiff base uses its indole NH donor site to form a hydrogen bond to the negatively charged phenolate O atom of the uncoordinated zwitterionic Schiff base. There is an intra-molecular N-H⋯O hydrogen bond in the coordinated and uncoordinated Schiff bases. The indole NH site of the uncoordinated Schiff base does not engage in a hydrogen-bond inter-action. The CH(2)-CH(2) group in the uncoordinated Schiff base is disordered equally over two positions.

Role of Helicobacter pylori virulence factor and genotypes in non-ulcer dyspepsia

Tan HJ, Rizal AM, Rosmadi MY, Goh KL

J Gastroenterol Hepatol, 2006 Jan;21(1 Pt 1):110-5.

PMID: 16706821

The role of Helicobacter pylori (HP) in non-ulcer dyspepsia is debatable. Eradicating HP will help a small group of non-ulcer dyspeptic patients. However, it is unclear which subgroup of patients will benefit from eradication therapy. The aim of the present study was to compare the cagA and cagE status, as well as vacA genotypes, of HP in non-ulcer dyspeptic patients who responded successfully to eradication therapy compared with those patients who did not.

Adsorption characteristics of malachite green on activated carbon derived from rice husks produced by chemical-thermal process

Rahman IA, Saad B, Shaidan S, Sya Rizal ES

Bioresour Technol, 2005 Sep;96(14):1578-83.

PMID: 15978990

Phosphoric acid (H(3)PO(4)) and sodium hydroxide (NaOH) treated rice husks, followed by carbonization in a flowing nitrogen were used to study the adsorption of malachite green (MG) in aqueous solution. The effect of adsorption on contact time, concentration of MG and adsorbent dosage of the samples treated or carbonized at different temperatures were investigated. The results reveal that the optimum carbonization temperature is 500 degrees C in order to obtain adsorption capacity that is comparable to the commercial activated carbon for the husks treated by H(3)PO(4). It is interesting to note that MG adsorbed preferably on carbon-rich than on silica rich-sites. It is found that the behaviour of H(3)PO(4) treated absorbent followed both the Langmuir and Freundlich models while NaOH treated best fitted to only the Langmuir model.

Distribution of Helicobacter pylori cagA, cagE and vacA in different ethnic groups in Kuala Lumpur, Malaysia

Tan HJ, Rizal AM, Rosmadi MY, Goh KL

J Gastroenterol Hepatol, 2005 Apr;20(4):589-94.

PMID: 15836708

There is a geographic variation in Helicobacter pylori (HP) genotypes and virulence factors. Cytotoxin associated genes A (cagA) and E (cagE), and certain vacuolating cytotoxin (vacA) genotypes are associated with peptic ulcer disease (PUD). There is also a different prevalence of PUD among different ethnic groups in Malaysia. The present study compared the distribution of vacA alleles and cagA and cagE status in three ethnic groups residing in Kuala Lumpur, Malaysia, and their association with clinical outcome.

Fulltext Remote Psychological First Aid (rPFA) in the time of Covid-19: A preliminary report of the Malaysian experience

Francis B, Juares Rizal A, Ahmad Sabki Z, Sulaiman AH

Asian J Psychiatr, 2020 Dec;54:102240.

PMID: 32593120 DOI: 10.1016/j.ajp.2020.102240

Fulltext Gender Differences on Methadone Maintenance Treatment Outcome among Patients with Opioid use Disorder: A Systematic Review

Mohemmad Rizal MR, Hayat Khan A, Noor Harun S, Saleh Z

J Pharm Bioallied Sci, 2020 Nov;12(Suppl 2):S657-S662.

PMID: 33828356 DOI: 10.4103/jpbs.JPBS_253_19

Objectives: The objective of this study was to review the significant differences of MMT outcomes related to drug use behavior, health status, and social behavioral functioning between genders.

Materials and Methods: A search of publication was conducted in PubMed/MEDLINE, Embase, CINAHL, PsycINFO, and Scopus database. Two reviewers independently screened the titles, abstracts, and keyword use for the search. Inclusion of studies was based on randomized controlled trials (RCTs) or observational studies that report the difference of opioid addiction treatment outcomes between genders. Any conflict between the two reviewers was resolved through discussion and consensus. The systematic review followed the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines and was registered in PROSPERO with a registration number CRD42019116261.

Results: A total of 25 studies were evaluated as part of qualitative synthesis. The review resulted in three main themes, which are (1) improving well-being and methadone-related outcome (five subthemes), (2) impact on social and behavioral (four subthemes), and (3) illicit drug use pattern-related behavior (four subthemes).

Conclusion: This review will highlight how men and women differ in methadone treatment outcomes for further application and improvement in the clinical setting.

Fulltext Innovation Diffusion: The Influence of Social Media Affordances on Complexity Reduction for Decision Making

Md Nordin S, Ahmad Rizal AR, Zolkepli IA

Front Psychol, 2021;12:705245.

PMID: 34803798 DOI: 10.3389/fpsyg.2021.705245

Social media is a prominent communication platform. Its active usage permeates all generations and it is imperative that the platform be fully optimized for knowledge transfer and innovation diffusion. However, there are several considerations regarding platform usage, including media affordances. Social media affordances enable users to interact with the world around them through features of modality, agency, interactivity, and navigation. Previous studies have indicated that social media affordances significantly influence user behavior and usage. However, research exploring the effect of social media affordances on knowledge acquisition and the reduction of decision-making complexities is limited. Therefore, focusing on 179 paddy farmers in Malaysia, this study examined the effect of social media affordances on information quality, knowledge acquisition, and complexity reduction regarding innovation adoption decisions using a quantitative approach. This study's findings reveal that social media affordances have a significant effect on perceived information quality, knowledge acquisition, and complexity reduction.

Fulltext "Fishing for lines": removal of endovascular catheters from the cardiovascular system

Wong AR, Suhaimi H, Ridzuan MA, Rizal MM, Saedah A

Singapore Med J, 2009 Oct;50(10):e358-61.

PMID: 19907875

We present two infants whose endovascular lines were accidentally cut or fractured, and had to be retrieved via transcatheter means in the cardiac catheterisation laboratory. The first case was a two-month-old infant with transposition of the great arteries, requiring an emergency balloon atrial septostomy. An indwelling vascular catheter that was placed in the right femoral vein was accidentally cut and had migrated into the inferior vena cava, before being retrieved. The second case was a one-week-old neonate who presented with pneumonia at birth, and had a long intravenous catheter placed in the left saphenous vein, which became fractured, and subsequently migrated into the heart. This case presented as a pulmonary embolus with haemodynamic instability, as the catheter had partially obstructed the right ventricular outflow tract. This was later retrieved via transcatheter means.

Fulltext The coexistence of anxiety and depressive personality traits in migraine

Tan HJ, Suganthi C, Dhachayani S, Rizal AM, Raymond AA

Singapore Med J, 2007 Apr;48(4):307-10.

PMID: 17384877

Migraine is associated with a variety of personality traits. The objective of this study was to reevaluate the personality traits using Minnesota Multiphasic Personality Inventory-2 (MMPI-2) in migraine patients diagnosed by applying the new International Classification of Headache Disorders-2 criteria.

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