Displaying publications 41 - 60 of 74 in total

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  1. Giant cell tumor of the tendon sheath in the knee of an 11-year-old girl
    Abdullah A, Abdullah S, Haflah NH, Ibrahim S
    J Chin Med Assoc, 2010 Jan;73(1):47-51.
    PMID: 20103492
    Giant cell tumors are commonly found over the flexor tendon sheath of the hand and wrist. However, giant cell tumors in the knee joint are rare, especially in children. We report an interesting case of an 11-year-old girl who presented with a painful lump on her right knee that enlarged over time. Clinically, she had fullness over the anterolateral part of her knee. Magnetic resonance imaging revealed an encapsulated mass inferior to the patella. The tumor measured 3 x 3.5 x 1.5 cm. Histopathological findings confirmed that it was a tenosynovial giant cell tumor. Because of initial mild symptoms, there was a delay of 2 years from the initial symptoms until tumor excision. Her follow-up period was 35 months, and her health to date is excellent with no recurrence. We believe that reporting this rare case will help clinicians update their knowledge on possible causes of lumps in the knee, and avoid diagnostic delay. It could also prove to be beneficial in arriving at a diagnosis in future cases.
    Matched MeSH terms: Tendons*
  2. Fulltext Important Metabolites in Maintaining Folate Cycle, Homocysteine, and Polyamine Metabolism Associated with Ranibizumab Treatment in Cultured Human Tenon's Fibroblasts
    Munirah Md Noh S, Hamimah Sheikh Abdul Kadir S, Vasudevan S
    Biomolecules, 2019 06 22;9(6).
    PMID: 31234474 DOI: 10.3390/biom9060243
    The anti-fibrotic properties of ranibizumab have been well documented. As an antagonist to vascular endothelial growth factor (VEGF), ranibizumab works by binding and neutralizing all active VEGF-A, thus limiting progressive cell growth and proliferation. Ranibizumab application in ocular diseases has shown remarkable desired effects; however, to date, its antifibrotic mechanism is not well understood. In this study, we identified metabolic changes in ranibizumab-treated human Tenon's fibroblasts (HTFs). Cultured HTFs were treated for 48 h with 0.5 mg/mL of ranibizumab and 0.5 mg/mL control IgG antibody which serves as a negative control. Samples from each group were injected into Agilent 6520 Q-TOF liquid chromatography/mass spectrometer (LC/MS) system to establish the metabolite expression in both ranibizumab treated cells and control group. Data obtained was analyzed using Agilent Mass Hunter Qualitative Analysis software to identify the most regulated metabolite following ranibizumab treatment. At p-value < 0.01 with the cut off value of two-fold change, 31 identified metabolites were found to be significantly upregulated in ranibizumab-treated group, with six of the mostly upregulated having insignificant role in fibroblast cell cycle and wound healing regulations. Meanwhile, 121 identified metabolites that were downregulated, and seven of the mostly downregulated are significantly involved in cell cycle and proliferation. Our findings suggest that ranibizumab abrogates the tissue scarring and wound healing process by regulating the expression of metabolites associated with fibrotic activity. In particular, we found that vitamin Bs are important in maintaining normal folate cycle, nucleotide synthesis, and homocysteine and spermidine metabolism. This study provides an insight into ranibizumab's mechanism of action in HTFs from the perspective of metabolomics.
    Matched MeSH terms: Tendons/cytology*
  3. Fulltext Is A New Combination of Tendon Transfers For Radial Nerve Palsy (RNP) Needed?
    Ramdhan I, Nawfar S, Paiman M
    Malays Orthop J, 2014 Mar;8(1):75-8.
    PMID: 25347622 MyJurnal DOI: 10.5704/MOJ.1403.006
    Radial nerve palsy following traumatic humeral diaphyseal fractures occurs uncommonly. Most recover with good outcome. However the cases with poor outcome or recovery will have tendon transfers to regain the lost functions. Various tendon transfer methods and choices are available in literatures citing acceptable to good results. We report a case of radial nerve transection secondary to a closed traumatic diaphyseal fracture of the humerus which did not improve despite the repair. As many conventional technique produce asynergistic muscle action with secondary post-transfer deformity, thus we had resorted to tendon transfer procedure using an unconventional donor and recipient tendons yielding good results. This new combination of tendon transfers was invented involves better dynamic correlation of synergistic muscles action and produces good outcome and hand function.
    Matched MeSH terms: Tendons
  4. Fulltext Isolated Peroneus Longus Tear - Commonly Missed Diagnosis of Lateral Ankle Pain: A Case Report
    Abd-Rasid AF, Bajuri MY
    Malays Orthop J, 2020 Jul;14(2):130-133.
    PMID: 32983388 DOI: 10.5704/MOJ.2007.011
    Peroneal tendon tear is a relatively common cause of lateral ankle pain but often missed due to mixed presentation or low index of suspicion. Left untreated, peroneal injuries can lead to persistent ankle pain, instability and ultimately substantial functional disabilities. An isolated peroneus longus tear is rare with the lowest incidence rate compared to isolated peroneus brevis tear and mixed tear of both peroneal tendon. This is a case report of a 49-year-old lady with a chronic left ankle pain who ultimately underwent surgery for an isolated peroneus longus tear.
    Matched MeSH terms: Tendons
  5. Fulltext Non-Traumatic Snapping Tendon on the Dorsal Aspect of the Thumb: A Diagnostic Challenge
    Kesu Belani L, Abdullah S, Soh EZF, Abd Jabar F, Nasseri Z
    Cureus, 2021 Apr 11;13(4):e14417.
    PMID: 33987066 DOI: 10.7759/cureus.14417
    A snapping tendon on the dorsal aspect of the thumb is a rare condition as opposed to the common triggering on the volar aspect of the thumb. This condition is known as triggering of the extensor pollicis longus (EPL). A 21-year-old female presented with a clicking or snapping sensation that was felt on the dorsum of her thumb when it is extended. There was no history of trauma. She worked in an ice-cream parlor with repetitive scooping ice-cream motions. Her triggering immediately resolved on releasing the EPL fascia ulnar to Lister's tubercle. Upon wake-up surgery, we could immediately confirm this. We recommend dynamic ultrasound as an investigation and do not recommend MRI. The surgical method of choice is either wake-up surgery or wide-awake local anesthesia no tourniquet (WALANT) surgery.
    Matched MeSH terms: Tendons
  6. Fulltext A 2-Year Demographic Study of Domestic Paediatric Hand Injuries Requiring Surgical Intervention in An Urban Hospital
    Shalimar, A., Jamari, S., Abdul Halim, A.R., Roohi, S.A., Naicker, A.S., Sharaf, I.
    Malays Orthop J, 2007;1(1):34-38.
    MyJurnal
    Domestic paediatric hand injuries make up the bulk of overall paediatric hand injuries. This is a retrospective study of domestic paediatric hand injuries admitted into an urban hospital that required surgical intervention. The most common injuries sustained were tendon injuries (24%), total amputations (20%) and lacerations wounds (16%). Accordingly the most common surgical interventions were tendon repairs (28%), toilet suturing (24%) and refashioning (20%). Parents and care providers need to be more vigilant and careful when supervising children including ensuring the safe storage of dangerous items. Sharp items may require additional safety features and warning labels.
    Matched MeSH terms: Tendons
  7. Fulltext A Study on the Absence of Palmaris Longus in a Multiracial Population
    Roohi, S.A., Choon-Sian, L, Shalimar, A., Tan,G.H., Naicker, A.S.
    Malays Orthop J, 2007;1(1):26-28.
    MyJurnal
    Palmaris longus is a dispensable muscle with a long tendon which is very useful in reconstructive surgery. It is absent 2.8 to 24% of the population depending on the race/ethnicity studied. Four hundred and fifty healthy subjects (equally distributed among Malaysia's 3 major ethnic groups) were clinically examined for the presence or absence of palmaris longus. This tendon was found to be absent unilaterally in 6.4% of study subjects, and bilaterally in 2.9% of study participants. Malays have a high prevalence of palmaris longus absence at 11.3% followed closely by Indians at 10.7% whilst Chinese had a low absence rate of 6.0%.
    Matched MeSH terms: Tendons
  8. Fulltext Spontaneous biceps tendon rupture in a patient with mixed connective tissue disease
    Ong SG
    Malays Fam Physician, 2013;8(3):31-3.
    PMID: 25893055 MyJurnal
    Tendon rupture is a rare complication that occurs in patients receiving corticosteroid therapy. We report a case of a middle-aged man with mixed connective tissue disease who presented with spontaneous biceps tendon rupture 5 weeks after initiation of high-dose corticosteroid therapy. Musculoskeletal ultrasonography was performed at the clinic and helped to confirm the diagnosis. It is a new imaging modality that is increasingly used in rheumatology clinics in Malaysia as it serves as an extension to physical examination. Musculoskeletal ultrasonography is preferred by patients as it is noninvasive, does not involve ionising radiation, painless, relatively inexpensive and can be performed readily at the clinic.
    KEYWORDS: corticosteroid; musculoskeletal ultrasonography; tendon rupture
    Matched MeSH terms: Tendons
  9. Fulltext Concomitant Traumatic Peroneal Tendon Dislocation and Medial Malleolus Fracture: A Case Report
    Vosoughi AR, Erfani MA
    Malays Orthop J, 2018 Mar;12(1):57-59.
    PMID: 29725517 DOI: 10.5704/MOJ.1803.014
    Peroneal tendon dislocation in association with medial malleolus fracture is a very rare traumatic injury to the ankle. A 19-year old male patient was referred after injury sustained in a motorcycle accident with car, with concomitant traumatic peroneal tendon dislocation and medial malleolus fracture. The possible mechanism of this unusual injury could have been sudden external rotation force to the pronated foot in full dorsiflexed position of the ankle. Diagnosis of peroneal tendon subluxation or dislocation should be carefully evaluated in patients with single medial malleolus fracture.
    Matched MeSH terms: Tendons
  10. Fulltext Analysis the influence of heart rate and muscle activity towards muscle fatique in layup workers
    Noor'Ain Azizan, Seri Rahayu Kamat, Nur Syafiqah Rayme, Ruzy Haryati Hambali
    Journal of Advanced Research in Applied Sciences and Engineering Technology, 2018;11(1):99-107.
    MyJurnal
    Repetitive movement can lead to the pain muscle, nerves, and tendons that cause by
    repetitive overuse of working task. The muscle will fatigue due to; repetitive
    movement, force that been applied, posture during working and duration of working.
    The stress level during working can influent the energy performance usage during
    working. The aim of this paper is to analyse the influence of heart rate and muscle
    activity of workers in composite manufacturing towards muscle fatigue. The data was
    collected for a worker in hand layup department and the Qualitative method was used
    in a way to investigate the working load and level of pain received by their body. Then,
    the Qualitative data was sorted and the respondent proceeded for a Quantitative
    method which involves muscle activity analysis and heart rate analysis. The tools that
    were used to conduct these experiments were surface electromyography (sEMG),
    Wristwatch with chest strap and perceived stress scale (PSS). The experimentation
    used to calculate the average reading of heart rate and muscle activity during working
    and detect the duration the muscle to start fatigue. Moreover, this paper analysed the
    relationship between heart rate and muscle activity through the duration of working.
    As an overall finding of this research, it was shown that the heart rate of the workers
    influence the muscle activity of workers and has high potential relationship to the
    fatigue of muscles of the workers in the layup department.
    Matched MeSH terms: Tendons
  11. Multiple arterial, neural and muscular variations in upper limb of a single cadaver
    Vollala VR, Nagabhooshana S, Bhat SM, Potu BK, Rodrigues V, Pamidi N
    Rom J Morphol Embryol, 2009;50(1):129-35.
    PMID: 19221659
    During routine dissection classes to undergraduate medical students, we have observed some important anatomic variations in the right upper limb of a 45-year-old cadaver. The anomalies were superficial ulnar artery, persistent median artery, variant superficial palmar arch, third head for biceps brachii, accessory head for flexor pollicis longus, variant insertion of pectoralis major, absence of musculocutaneous nerve, coracobrachialis muscle supplied by lateral root of median nerve and anomalous branching of median nerve in arm and forearm. Although there are individual reports about these variations, the combination of these variations in one cadaver has not previously been described in the literature consulted. Awareness of these variations is necessary to avoid complications during radiodiagnostic procedures or surgeries in the upper limb.
    Matched MeSH terms: Tendons/abnormalities; Tendons/pathology
  12. Fulltext Peroneus quartus and peroneal tendoscopy
    Yong CK
    Med J Malaysia, 2006 Dec;61 Suppl B:45-7.
    PMID: 17605180
    This is a report of a case of peroneal subluxation caused by peroneus quartus, a supernumerary muscle in the peroneal muscle group. Peroneus quartus' anatomy and its clinical relevance in lateral ankle pain, swelling and peroneal subluxation are described. It may be accurately diagnosed by peroneal tendoscopy. The technical note of this procedure is also described.
    Matched MeSH terms: Tendons/pathology; Tendons/surgery*
  13. Morphometric analysis and surgical adequacy of palmaris longus as a tendon graft. A systematic review of cadaveric studies
    Yammine K, Erić M
    Surg Radiol Anat, 2020 Mar;42(3):259-267.
    PMID: 31741040 DOI: 10.1007/s00276-019-02381-x
    INTRODUCTION: The tendon of the palmaris longus is commonly used as a tendon graft in many reconstructive surgeries. Easy to access and at proximity to the hand, the palmaris longus tendon is considered as the optimal tendon source for hand reconstructive surgery. However, and besides its inconsistency, the size of the palmaris longus tendon is reported to show variability. The aim of this study is to look for the surgical adequacy of the palmaris longus tendon by conducting a quantitative synthesis on its length and width in human populations and its correlation with the forearm length.

    METHODS: Twenty-four studies met the inclusion criteria including 1761 cadaveric limbs.

    RESULTS: The results were as following: (a) the mean palmaris longus tendon length was of 13.9 ± 2.6 cm, (b) the mean ratio palmaris longus tendon length/forearm length was of 0.545 ± 0.06, (c) the weighted correlation value was of 0.686, and (d) the mean palmaris longus tendon width was of 4.0 ± 1.7 mm. Only five studies reported a palmaris longus tendon length of more than 15 cm. The palmaris longus tendon length was shown to vary between ancestries; the Japanese had the shortest while Malaysian the longest palmaris longus tendons. All studies but one reported a palmaris longus tendon mean width of more than 3 mm where the minimal mean palmaris longus tendon width was of 2.5 mm.

    CONCLUSION: While the requested length depends on the recipient site and/or type of reconstructive surgery, the palmaris longus tendon often met the required diameter for grafting. Our review demonstrated that while palmaris longus length varies between ancestries, its width is often adequate for grafting. In addition, the forearm length could be a good predictor of palmaris longus tendon length; such correlation could assist surgeons when planning to use palmaris longus tendon as a graft source.

    Matched MeSH terms: Tendons/anatomy & histology*; Tendons/transplantation
  14. The Linburg-Comstock anomaly: incidence in Malaysians and effect on pinch strength
    Low TH, Faruk Senan NA, Ahmad TS
    J Hand Surg Am, 2012 May;37(5):930-2.
    PMID: 22386556 DOI: 10.1016/j.jhsa.2012.01.020
    To obtain epidemiologic data on the Linburg-Comstock anomaly in Malaysia and to study the effect of the anomaly on key pinch strength.
    Matched MeSH terms: Tendons/abnormalities*; Tendons/physiopathology
  15. Fulltext Joint torque reduction of a three dimensional redundant planar manipulator
    Yahya S, Moghavvemi M, Almurib HA
    Sensors (Basel), 2012;12(6):6869-92.
    PMID: 22969326 DOI: 10.3390/s120606869
    Research on joint torque reduction in robot manipulators has received considerable attention in recent years. Minimizing the computational complexity of torque optimization and the ability to calculate the magnitude of the joint torque accurately will result in a safe operation without overloading the joint actuators. This paper presents a mechanical design for a three dimensional planar redundant manipulator with the advantage of the reduction in the number of motors needed to control the joint angle, leading to a decrease in the weight of the manipulator. Many efforts have been focused on decreasing the weight of manipulators, such as using lightweight joints design or setting the actuators at the base of the manipulator and using tendons for the transmission of power to these joints. By using the design of this paper, only three motors are needed to control any n degrees of freedom in a three dimensional planar redundant manipulator instead of n motors. Therefore this design is very effective to decrease the weight of the manipulator as well as the number of motors needed to control the manipulator. In this paper, the torque of all the joints are calculated for the proposed manipulator (with three motors) and the conventional three dimensional planar manipulator (with one motor for each degree of freedom) to show the effectiveness of the proposed manipulator for decreasing the weight of the manipulator and minimizing driving joint torques.
    Matched MeSH terms: Tendons
  16. Fulltext A Modified Method for Reconstruction of Chronic Rupture of the Quadriceps Tendon after Total Knee Replacement
    Singh, S., Choon, S.K., Tai, C.C.
    Malays Orthop J, 2008;2(2):34-36.
    MyJurnal
    We describe herein a modified technique for reconstruction of chronic rupture of the quadriceps tendon in a patient with bilateral total knee replacement and distal realignment of the patella. The surgery involved the application of a Dacron graft and the ‘double eights’ technique. The patient achieved satisfactory results after surgery and we believe that this technique of reconstruction offers advantages over other methods.
    Matched MeSH terms: Tendons
  17. Fulltext Novel method to estimate the length of the palmaris longus tendon
    Manohar, A., Ramal, L.
    Malaysian Journal of Medicine and Health Sciences, 2013;9(2):19-24.
    MyJurnal
    Palmaris longus is tendon of choice in reconstructive, plastic and cosmetic surgeries. Thus, a suitable length is required and it would be more convenient if the length of the tendon of the palmaris longus could be estimated before harvesting. This study was carried out to determine the relationship between the length and width of the palmaris longus tendon and the length of forearm and hand, the relationship between the length and the width of the palmaris longus tendon and wrist width and wrist circumference, as well as to identify a technique to estimate the length of the tendinous part of palmaris longus before harvesting it. A standardized proforma was used to collect the data of each of the 31 cadavers upper limbs. These data were analysed using SPSS software version 17. It is important to note that p value less than 0.05 is considered as statistically significant in this study. Out of the 31 upper limbs, palmaris longus tendon was absent in 3 (9.68%). Meanwhile, the mean length and width of the palmaris longus tendon was found to be 16.20 cm and 0.48 cm, respectively. The mean length of the forearm and hand was 26.6 cm and 21.2 cm, respectively. The mean width of the wrist and wrist circumference was 8.2 cm and 14.82 cm, respectively. These indicate a significant and moderate relationship between the length of palmaris longus tendon and the length of forearm (r = 0.49, r2 = 0.24, p < 0.01). In addition, there was also a significant relationship between the length of palmaris longus tendon and the length of hand (r = 0.56, p < 0.01). This paper presents the technique used to estimate the length and width of the tendinous part of palmaris longus before harvesting. The length of palmaris longus can be estimated pre-operatively by measuring the length of the hand by using the technique explained in this paper.
    Matched MeSH terms: Tendons
  18. Fulltext Ganglion of the Flexor Tendon Sheath at the A2 Pulley - Case Report
    Gunaseelan P, Jeremy P, Chua CK, Rashdeen F
    Malays Orthop J, 2015 Mar;9(1):28-29.
    PMID: 28435592 MyJurnal DOI: 10.5704/MOJ.1503.002
    There are few reported cases of flexor tendon sheath ganglion arising from the A2 pulley. We report a case of a flexor tendon sheath ganglion in a 17-year old female who presented with pain, triggering and a swelling at the base of her right ring finger. During the excision biopsy, a ganglion measuring 0.5×0.8×0.4 cm in size was removed from the A2 pulley area.
    Matched MeSH terms: Tendons
  19. Fulltext A mini review on the basic knowledge on tendon: revisiting the normal & injured tendon
    Tan, S.L., Selvaratnam, L., Ahmad, T.S.
    JUMMEC, 2015;18(2):1-14.
    MyJurnal
    Tendon is a dense connective tissue that connects muscle to bone. Tendon can adapt to mechanical forces passing across it, through a reciprocal relationship between its cellular components (tenocytes and tenoblasts) and the extracellular matrix (ECM). In early development, the formation of scleraxis-expressing tendon progenitor population in the sclerotome is induced by a fibroblast growth factor signal secreted by the myotome. Tendon injury has been defined as a loss of cells or ECM caused by trauma. It represents a failure of cells and matrix adaptation to mechanical loading. Injury initiates attempts of tendon to repair itself, which has been defined as replacement of damaged or lost cells and ECM by new cells or new matrices. Tendon healing generally consists of four different phases: the inflammatory, proliferation, differentiation and remodelling phases. Clinically, tendons are repaired with a variety of surgical techniques, which show various degrees of success. In order to improve the conventional tendon repair methods, current tendon tissue engineering aims to investigate a repair method which can restore tissue defects with living cells, or cell based therapy. Advances in tissue engineering techniques would potentially yield to a cell-based product that could regenerate functional tendon tissue.
    Matched MeSH terms: Tendons
  20. Fulltext Separate Belly and Tendon of Flexor Digitorum Superficialis to the Fifth Digit
    Rao M, Ashwini LS, Somayaji SN, Mishra S, Guru A, Rao A
    Oman Med J, 2011 Nov;26(6):e027.
    PMID: 28861181 DOI: 10.5001/omj.2011.120
    Variation in the origin of long flexor tendons in the anterior compartment of forearm is common. During routine cadaveric dissection at Melaka Manipal Medical College (Manipal Campus), we observed a separate muscle belly and tendon of flexor digitorum superficialis (FDS) to the fifth digit in the right upper limb of a 60 year-old male cadaver. The anomalous muscle belly originated from the common flexor tendon from the medial epicondyle of the humerus and continued as a thin tendon at the middle of the forearm to get inserted into the middle phalanx of the fifth digit. This can be considered as a case of split flexor digitorum superficialis. Such muscle variations and knowledge of their frequency, appearance, and location can be helpful for surgeons.
    Matched MeSH terms: Tendons
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