MyMedR

The Long-Term Public Health Benefits of Breastfeeding

Binns C, Lee M, Low WY

Asia Pac J Public Health, 2016 Jan;28(1):7-14.

PMID: 26792873 DOI: 10.1177/1010539515624964

Breastfeeding has many health benefits, both in the short term and the longer term, to infants and their mothers. There is an increasing number of studies that report on associations between breastfeeding and long-term protection against chronic disease. Recent research evidence is reviewed in this study, building on previous authoritative reviews. The recent World Health Organization reviews of the short- and long-term benefits of breastfeeding concluded that there was strong evidence for many public health benefits of breastfeeding. Cognitive development is improved by breastfeeding, and infants who are breastfed and mothers who breastfeed have lower rates of obesity. Other chronic diseases that are reduced by breastfeeding include diabetes (both type 1 and type 2), obesity, hypertension, cardiovascular disease, hyperlipidemia, and some types of cancer.

Matched MeSH terms: Chronic Disease/prevention & control*

Phenolic Metabolites as Therapeutics for Chronic Diseases: One Researcher's PAINS Is Another's Translatable Polypharmacology

Benjamin MM, Choo YM, Dickinson CF, Tius MA, Ferreira D, Hamann MT

J Nat Prod, 2026 Oct 23;89(10):2751-2763.

PMID: 42924965 DOI: 10.1021/acs.jnatprod.6c00532

Phenols, natural and semisynthetic compounds in which a hydroxylated or oxygenated aromatic scaffold is a defining structural feature, occupy a paradoxical position in drug discovery. On the one hand, these compounds are frequently scrutinized for triggering Pan-Assay INterference compoundS (PAINS) structural alerts; on the other, their reported wide-ranging bioactivities support continued evaluation as potential therapeutics, particularly given that several phenolic compounds and mixtures have attained FDA approval for treating diseases ranging from cancers to viral infections. Accordingly, this perspective contrasts concerns raised by PAINS structural alerts with reported broad pharmacological activity and proposes a framework for the rational evaluation as well as the synthetic development of phenolic scaffolds.

Matched MeSH terms: Chronic Disease/drug therapy

The science of respiratory characteristics in individuals with chronic low back pain: Interpreting through statistical perspective

Mohan V, Paungmali A, Sitilertpisan P

J Bodyw Mov Ther, 2018 01;22(1):11-12.

PMID: 29332732 DOI: 10.1016/j.jbmt.2017.03.017

Matched MeSH terms: Chronic Disease

Fulltext Factors affecting health-related quality of life among paediatric patients with thalassemia: a review of literature

Wan Adnan Wan-Nor-Asyikeen, Ab Hamid Siti-Azrin, Maryam Mohd Zulkifli, Alwi Zilfalil

Malaysian Journal of Paediatrics and Child Health, 2017;23(1):0-0.

MyJurnal

Thalassaemia is a hereditary blood disorder that is becoming a major health problem all over the world. This chronic illness harms the quality of life of the sufferers by interrupting their physical activities, school performance and social life. Hence, this review takes aim to assess the factors affecting the quality of life of thalassaemia among paediatrics patients. A comprehensive electronic search was conducted by using PubMed, Google Scholar and Science Direct. The search was limited to those articles written in English language and by using Pediatrics Quality of Life Inventory (PedsQLTM) 4.0 generic core scale questionnaire only. This review notifies emerging knowledge regarding the factors affecting the quality of life among thalassaemia patients and its implications in the essential core domains for paediatrics health-related quality of life measurements: physical, emotional, social and school functioning. It also empowers a better understanding regarding thalassaemia and assists as a foundation for the development of the effective preventive strategies for it.

Matched MeSH terms: Chronic Disease

Fulltext A case of isolated laryngeal candidiasis mimicking laryngeal carcinoma in an immunocompetent individual

Nair AB, Chaturvedi J, Venkatasubbareddy MB, Correa M, Rajan N, Sawkar A

Malays J Med Sci, 2011 Jul;18(3):75-8.

PMID: 22135605

Respiratory fungal infections are usually found in immunocompromised individuals who have received either long-term steroid therapy or broad-spectrum anti-microbial therapy or have a non-resolving underlying chronic disease. These infections are seen as a part of bronchopulmonary fungal infections, and their isolated and primary occurrence as laryngeal diseases is highly uncommon. Laryngeal fungal infections can also mimic various diseases, such as gastroesophageal reflux disease, granulomatous diseases, leukoplakia, and carcinoma, thereby misleading the treating team from correct diagnosis and management. It is therefore important to identify the lesion at the earliest point possible to avoid morbid or life-threatening consequences. We report a case of isolated laryngeal candidiasis in an immunocompetent Indian male with an unusual presentation mimicking laryngeal carcinoma. The clinical and histological features are highlighted with a review of relevant literature to demonstrate the possibility of such an isolated fungal lesion, even in an immunocompetent individual.

Matched MeSH terms: Chronic Disease

Fulltext Assessment and management of chronic cough

Wong CMM, Lim KH, Liam CK

Med J Malaysia, 2002 Dec;57(4):515-23; quiz 524-5.

PMID: 12733182

Matched MeSH terms: Chronic Disease

Fulltext Chronic osteomyelitis due to Burkholderia pseudomallei

Kareem BA, Aiyar S, Marshal DS

Med J Malaysia, 1995 Mar;50(1):116.

PMID: 7752966

Matched MeSH terms: Chronic Disease

Fulltext Life events and parasuicides in Hospital Kuala Lumpur, Malaysia

Hamidin, A., Maniam, T.

Malaysian Journal of Medicine and Health Sciences, 2011;7(2):45-52.

MyJurnal

Objective: The aim of this study is to compare the prevalence of life events among parasuicide patients
with the prevalence of similar life events among age, sex and race matched patients with non-chronic
medical illness. Methods: A hospital-based case-control study using convenience sampling method
was conducted in Hospital Kuala Lumpur for a period of three and a half months. A total of 50 patients
admitted consecutively after an episode of parasuicide and who fulfilled criteria for entry into the study
agreed to participate. For each case one age-, sex- and race-matched control was selected from the list of patients who were admitted to the same hospital for non-chronic medical illness. Result: Statistical analysis showed that compared with medically ill patients, parasuicide patients had significantly higher prevalence of threatening life events six months (p

Matched MeSH terms: Chronic Disease

Fulltext The CORFIS experience

Low, Wilson

Malays Fam Physician, 2010;5(1):57-58.

MyJurnal

The CORFIS Programme was conceived by the Clinical Research Centre, HKL in 2007 in the hope of piloting a chronic disease management strategy among the Malaysian private general practitioners to tackle the current epidemic of cardiovascular chronic diseases. 1-5 The programme was implementing as a clinical research study i.e. a community trial in June 2007. The study recruited a total of 70 GPs within the Klang Valley region with an enrolment of 705 patients diagnosed with hypertension, diabetes mellitus (DM) and/or hyperlipidaemia. The GPs were clustered randomised centrally in a 2:1 ratio to provide either chronic disease care (CORFIS) or usual care. Patients were followed up for a period of 6 months from date of enrolment. (Copied from article).

Matched MeSH terms: Chronic Disease

A case of tinea nigra in Britain

Chadfield HW, Campbell CK

Br J Dermatol, 1972 Nov;87(5):505-8.

PMID: 4647125

Matched MeSH terms: Chronic Disease

Fulltext A snapshot of the global policies and practices of medicine use reviews by community pharmacist in chronic diseases: A narrative review

Mubarak N, Raja SA, Khan TM, Zin CS

J Pak Med Assoc, 2021 Mar;71(3):950-965.

PMID: 34057955 DOI: 10.47391/JPMA.058

Medicine use review is a tool to improve medication adherence and safety. Current narrative review was planned to explore global policies and practices of medicine use review by community pharmacists in chronic diseases and its impact and way forward for low- and middle-income countries. Key words, such as ″medicine use review″, ″medication therapy management″ and ″community pharmacy″ were used for search on PubMed and CINAHL databases for articles published from 2004 to 2019. Medicine use review has opened an avenue of ongoing collaboration between community pharmacists and general practitioners. High-income countries have witnessed a gradual yet cautious adoption of these services through effective policy shift. In terms of practices and impact, the situation in high-income countries was promising where on an average ″type-II″ medicine use review was widely in practice and had improved clinical, humanistic and economic outcomes in chronic disease. However, in low- and middle-income countries, a paucity of effective policies was noted. Nevertheless, an emergent recognition of the potential of community pharmacists to contribute to the management of chronic diseases was evident.

Matched MeSH terms: Chronic Disease

Fulltext Surgery for isolated non-inflammatory chronic total occlusion of the left main coronary artery: a case report and literature review

Azam AF, How LA, Nor A, Badmanaban B, Sachithanandan A

Med J Malaysia, 2011 Oct;66(4):374-5.

PMID: 22299565 MyJurnal

Chronic total occlusion (CTO) of the left main coronary artery (LMCA) is a rare manifestation of coronary artery disease (CAD) and defined by a total absence of antegrade blood flow to the left anterior descending (LAD) and circumflex (Cx) system. Patients are at high risk of myocardial ischaemia as a sizeable area of myocardium is at risk and thus require urgent intervention. Surgery is the treatment of choice especially with CTO lesions as percutaneous coronary intervention has limited success with a high restenosis rate. We report a rare case of a young Chinese male who presented acutely with a myocardial infarction and discuss the aetiology and peri-operative technical considerations for successful surgery with this condition.

Matched MeSH terms: Chronic Disease

Exfoliative cheilitis: report of a case

Mani SA, Shareef BT

J Can Dent Assoc, 2007 Sep;73(7):629-32.

PMID: 17868515

Exfoliative cheilitis, one of a spectrum of diseases that affect the vermilion border of the lips, is uncommon and has no known cause. However, factors such as stress and some psychiatric conditions are associated with the onset of the disease. This condition is disabling because esthetics and normal functions such as eating, speaking and smiling are compromised. The lack of specific treatment makes exfoliative cheilitis a chronic disease that radically affects a person"s life. This report attempts to further investigate the clinical course of the disease and provides detailed illustrations of the cyclical nature of the disease.

Matched MeSH terms: Chronic Disease

How common is generalized pustular psoriasis in Malaysia?

Br J Dermatol, 2023 Sep 15;189(4):e73.

PMID: 37713514 DOI: 10.1093/bjd/ljad292

Matched MeSH terms: Chronic Disease

Determinants of multimorbidity in low- and middle-income countries: A systematic review of longitudinal studies and discovery of evidence gaps

Tan MMC, Barbosa MG, Pinho PJMR, Assefa E, Keinert AÁM, Hanlon C, et al.

Obes Rev, 2024 Feb;25(2):e13661.

PMID: 38105610 DOI: 10.1111/obr.13661

Multimorbidity-the coexistence of at least two chronic health conditions within the same individual-is an important global health challenge. In high-income countries (HICs), multimorbidity is dominated by non-communicable diseases (NCDs); whereas, the situation may be different in low- and middle-income countries (LMICs), where chronic communicable diseases remain prominent. The aim of this systematic review was to identify determinants (including risk and protective factors) and potential mechanisms underlying multimorbidity from published longitudinal studies across diverse population-based or community-dwelling populations in LMICs. We systematically searched three electronic databases (Medline, Embase, and Global Health) using pre-defined search terms and selection criteria, complemented by hand-searching. All titles, abstracts, and full texts were independently screened by two reviewers from a pool of four researchers. Data extraction and reporting were according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Methodological quality and risk of bias assessment was performed using the Newcastle-Ottawa Scale for cohort studies. Data were summarized using narrative synthesis. The search yielded 1782 records. Of the 52 full-text articles included for review, 8 longitudinal population-based studies were included for final data synthesis. Almost all studies were conducted in Asia, with only one from South America and none from Africa. All studies were published in the last decade, with half published in the year 2021. The definitions used for multimorbidity were heterogeneous, including 3-16 chronic conditions per study. The leading chronic conditions were heart disease, stroke, and diabetes, and there was a lack of consideration of mental health conditions (MHCs), infectious diseases, and undernutrition. Prospectively evaluated determinants included socio-economic status, markers of social inequities, childhood adversity, lifestyle behaviors, obesity, dyslipidemia, and disability. This review revealed a paucity of evidence from LMICs and a geographical bias in the distribution of multimorbidity research. Longitudinal research into epidemiological aspects of multimorbidity is warranted to build up scientific evidence in regions beyond Asia. Such evidence can provide a detailed picture of disease development, with important implications for community, clinical, and interventions in LMICs. The heterogeneity in study designs, exposures, outcomes, and statistical methods observed in the present review calls for greater methodological standardisation while conducting epidemiological studies on multimorbidity. The limited evidence for MHCs, infectious diseases, and undernutrition as components of multimorbidity calls for a more comprehensive definition of multimorbidity globally.

Matched MeSH terms: Chronic Disease

Profile of travelers with preexisting medical conditions attending a specialist travel medicine clinic in Ireland

Han CT, Flaherty G

J Travel Med, 2015 Sep-Oct;22(5):312-7.

PMID: 26095866 DOI: 10.1111/jtm.12221

BACKGROUND: Patients with complex medical comorbidities travel for protracted periods to remote destinations, often with limited access to medical care. Few descriptions are available of their preexisting health burden. This study aimed to characterize preexisting medical conditions and medications of travelers seeking pre-travel health advice at a specialized travel medicine clinic.
METHODS: Records of travelers attending the Galway Tropical Medical Bureau clinic between 2008 and 2014 were examined and information relating to past medical history was entered into a database. Data were recorded only where the traveler had a documented medical history and/or was taking medications.
RESULTS: Of the 4,817 records available, 56% had a documented medical history and 24% listed medications. The majority of travelers with preexisting conditions were female. The mean age of the cohort was 31.68 years. The mean period remaining before the planned trip was 40 days. Southeast Asia was the most popular single destination, and 17% of travelers with medical conditions were traveling alone. The most frequently reported conditions were allergies (20%), insect bite sensitivity (15%), asthma (11%), psychiatric conditions (4%), and hypertension (3%). Of the 30 diabetic travelers, 14 required insulin; 4.5% of travelers were taking immunosuppressant drugs, including corticosteroids. Half of the female travelers were taking the oral contraceptive pill while 11 travelers were pregnant at the time of their pre-travel consultation.
CONCLUSIONS: This study provides an insight into the medical profile of travelers attending a travel health clinic. The diverse range of diseases reported highlights the importance of educating physicians and nurses about the specific travel health risks associated with particular conditions. Knowledge of the effects of travel on underlying medical conditions will inform the pre-travel health consultation.

Matched MeSH terms: Chronic Disease/epidemiology; Chronic Disease/prevention & control; Chronic Disease/therapy*

Fulltext Knowledge, perceptions, and attitudes of dental students towards obesity

Awan KH, Khan S, Abadeen Z, Khalid T

Saudi Dent J, 2016 Jan;28(1):44-8.

PMID: 26792969 DOI: 10.1016/j.sdentj.2015.01.005

Obesity is a chronic medical condition associated with various oral health problems. The aim of this study was to assess the knowledge, perceptions, and attitudes of dental students towards obesity.

Matched MeSH terms: Chronic Disease

A proposed cascade of vascular events leading to granulomatous amoebic encephalitis

Baig AM, Khan NA

Microb Pathog, 2015 Nov;88:48-51.

PMID: 26276705 DOI: 10.1016/j.micpath.2015.08.005

Granulomatous amoebic encephalitis due to Acanthamoeba is a chronic disease that almost always results in death. Hematogenous spread is a pre-requisite followed by amoebae invasion of the blood-brain barrier to enter the central nervous system. Given the systemic nature of this infection, a significant latent period of several months before the appearance of clinical manifestations is puzzling. Based on reported cases, here we propose pathogenetic mechanisms that explain the above described latency of the disease.

Matched MeSH terms: Chronic Disease

Chronic Silicosis

Ing SK, Kho SS

N Engl J Med, 2024 May 16;390(19):e46.

PMID: 38738767 DOI: 10.1056/NEJMicm2312247

Matched MeSH terms: Chronic Disease

Fulltext Comparing attenuation parameter and liver stiffness measurement using Hepatus and Fibroscan for the evaluation of steatosis and fibrosis in patients with chronic liver disease: A prospective study

Lim CE, Sinnanaidu RP, Ng XT, Teh JY, Khamis F, Vijayananthan A, et al.

PLoS One, 2026;21(11):e0359831.

PMID: 42986898 DOI: 10.1371/journal.pone.0359831

BACKGROUND: There are limited studies comparing Hepatus (HP), a novel visual transient elastography device with Fibroscan (FS), one of the most studied and validated non-invasive tests in the field of hepatology.

METHODOLOGY: HP and FS examinations were performed on patients with chronic liver disease by two operators, healthcare providers from different background, twice on each patient, at two different time points, independent of each other.

RESULTS: The data for 158 patients with 1264 examinations was analysed. There was moderate to strong correlation for attenuation parameter (Spearman's rho 0.67, p S0, > S1 and >S2 and substantial agreement for diagnosis of unlikely and likely compensated advanced chronic liver disease. The interquartile range (IQR) for attenuation parameter and IQR/median for LSM were lower for HP compared with FS (12 dB/m vs 33 dB/m, p

Matched MeSH terms: Chronic Disease

Displaying publications 41 - 60 of 576 in total