Displaying publications 6701 - 6720 of 24636 in total

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  1. Fulltext Sequence polymorphism and haplogroup data of the hypervariable regions on mtDNA in Semoq Beri population
    Zahidin MA, Omar WBW, Taib WRW, Japning JRR, Abdullah MT
    Data Brief, 2018 Dec;21:2609-2615.
    PMID: 30761343 DOI: 10.1016/j.dib.2018.10.158
    Orang Asli is the aboriginal people in Peninsular Malaysia who have been recognized as indigenous to the country and still practicing traditional lifestyle. The molecular interest on the Orang Asli started when the earliest prehistoric migration occurred approximately 200 kya and entering Peninsular Malaysia 50 kya in stages. A total of three groups of Orang Asli present in Peninsular Malaysia, namely, Negrito also known as Semang, Senoi and Proto Malays. Through records, there is no research has been conducted on mtDNA variations in the Semoq Beri population, one of the tribes in Senoi group. In this report, variations of mtDNA were analysed in the population in Hulu Terengganu as an initial effort to establish the genetic characterisation and elucidating the history of Orang Asli expansion in Peninsular Malaysia. An array of mtDNA parameters was estimated and the observed polymorphisms with their respective haplogroups in comparison to rCRS were inferred respectively. The DNA sequences are registered in the NCBI with accession numbers KY853670-KY853753.
    Matched MeSH terms: Malaysia
  2. The first species of Siamites Franz (Coleoptera, Staphylinidae, Scydmaeninae) in East Malaysia
    JaŁoszyŃski P
    Zootaxa, 2019 Jan 17;4545(3):447-450.
    PMID: 30790914 DOI: 10.11646/zootaxa.4545.3.11
    The glandulariine genus Siamites is amongst the rarest Oriental ant-like stone beetles. To date, only three species have been known, distributed in Thailand and Vietnam. A new species, S. sarawakensis sp. n. is described here, based on a male specimen collected in Sarawak, East Malaysia. This finding extends the known range of Siamites over 1200 km southeastward.
    Matched MeSH terms: Malaysia
  3. Fulltext Improvement of awareness and knowledge in breast cancer using online learning
    Nurulhuda, M. H., Norwati, D., Sit Norazlina, J., Husbani, M. A. R.
    Asian Journal of Medicine and Biomedicine, 2018;2(1):0-0.
    MyJurnal
    Background: Breast cancer is the most common cancer and the leading cause of cancer death among women in
    Malaysia, accounting to 32.1% of all cancer among women. Preventive activities of breast health especially
    mammogram screening was found to be effective in reducing the mortality and morbidities related to breast cancer. .
    However, the number of people who come for screening is still unsatisfactory. Many patients come in advanced stage
    of breast cancer attributed by lack of awareness and knowledge of the disease. The aim of this study was to introduce
    a multimodality online course on breast cancer and its screening; and to measure its effectiveness in providing the
    awareness and knowledge in breast cancer. Methodology: An online course was designed incorporating essential
    knowledge regarding breast cancer and its screening. Group sampling was done to sample 30 undergraduate students.
    Knowledge and awareness on breast cancer and its screening was measured using a validated questionnaire pre and
    post exposure to the online course. Results: There was significant difference in Pre- &Post-exposure test knowledge
    (p
    Matched MeSH terms: Malaysia
  4. Evaluation of a pilot community-based bicycle helmet promotion program in Malaysia
    Krishnan R, Cheng OT, Amar Singh HSS, Wong WY, Yip RCW, Shamini V
    Family Physician, 1996;9:17-22.
    Bicycle fatalities constituted 5% of road fatalities in 1995. A helmet, properly worn, is the most effective measure to prevent head injury to a cyclist in the event of a crash. We studied the knowledge, attitude and practice of children in two secondary schools (Ipoh and Kulim) with respect to bicycle helmet use before instituting a program for helmet use. Although there were no major differences in knowledge, attitude and practice of students in the two groups, children in the Ipoh program failed to wear helmets while the children in the Kulim program complied over a one year period. The main reason for failure of the helmet progranl in Ipoh were negative peer influence. The Kulim helmet program was integrated with a bicycle safety course conducted by dedicated teachers. The quasi experimental study resulted in increased awareness of the importance of bicycle helmets among school children in Kulim Keywords: Bicycle helmet, road traffic injury, prevention.
    Matched MeSH terms: Malaysia
  5. Knowledge, attitude and practice of parents of children with Thalassaemia towards their children's disease.Pengetahuan, sikap serta tindakan yang diambil oleh ibubapa kanak-kanak berpenyakit Thalassaemia terhadap penyakit anak mereka.]
    Krishnan R, Chin WL, Sinniah D
    Family Physician, 1991;3:24-27.
    We studied the knowledge, attitude and practice of 27 parents of children with Thalassaemia towards their children's disease. The parents' knowledge was satisfactory. Most of them did not reveal details of the disease to their affected children. Some of them had further children despite being explained the risk of recurrence. Parents found it difficult to obtain regular blood donors and some had to resort to 'buying' blood. The Malaysian Association of Thalassaemia has a role to play in the education of patients, their parents and the public.
    Matched MeSH terms: Malaysia
  6. Temporomandibular joint disorders: a review for physicians
    Khoo SP
    Family Physician, 1994;6:2-5.
    Temporomandibular disorders are the commonest orofacila pain. Many of them present themselves to the primary care physician. A fundamental familiarity with this disorder is essential for proper diagnosis and management.
    Matched MeSH terms: Malaysia
  7. Fulltext Opportunities for immunization in a paediatric outpatient clinic
    Krishnan R, Chen ST
    Family Physician, 1990;2(2&3):38-40.
    Study site: paediatric clinic, University Malaya Medical Centre (UMMC), Kuala Lumpur, Malaysia
    Matched MeSH terms: Malaysia
  8. Lightning burns
    Krishnan R
    Family Physician, 1991;3:57-58.
    A 7 year-old Malay child with lightning burns is reported. Lightning injuries are rare. Victims who are clinically 'dead' may recover normally if resuscitation is carried out for prolonged periods.
    Matched MeSH terms: Malaysia
  9. Factors associated with diabetic control
    Ruzita AT, Osman A, Khalid AK
    Family Physician, 1994;6:12-14.
    The aim of the study was to determine the factors associated with diabetic control among Non Insulin Dependent Diabetes Mellitus (NIDDM) in a Felda settlement area. METHODS: We analyzed the anthropometric and metabolic data of sixty three NIDDM patients in Felda Sg Koyan, Raub, Pahang. Diabetic control, was measured by glycated hemoglobin (HbA1) and fructosamine; it showed a strong correlation (r=12.8 and p-0.001). With the use of a multivariate regression model, which was adjusted for sex, age, dhration of diabetes, body mass index (BMI) and systolic blood pressure, we found that the occurrence of higher fructosamine was associated with significantly higher HbA1 (F =7.8, p=0.01). RESULTS: Obesity was present in 72% of diabetic patients with BMI>25 and had a mean duration of diabetes of 6+4 years. Mean HbAl among males (6.8 + 1.6%) were significantly different (p 0.05) to diabetic control. CONCLUSIONS: The study showed that males have a better diabetic control than females. Poor control was observed among diabetics who had diabetes for more than five years.
    Matched MeSH terms: Malaysia
  10. Acute right upper quadrant pain: Evaluation by ultrasound at the General Hospital, Kota Bharu
    Sathyamoorthy P
    Family Physician, 1992;4:20-22.
    A retrospective study of 100 patients with acute right upper quadrant pain was performed in order to indicate the diagnostic role of ultrasound including the diagnostic role of ultrasound including guided percutaneous procedures in the evaluation of such cases at the General Hospital Kota Bharu (GH, KB). In the majority of these patients the leading clinical consideration was acute cholecystitis. In all the patients the initial sonographic diagnoses were compared with the final diagnoses. In 35 patients (35%) biliary pathology was diagnosed. In this group the conographic correlation was good. In 65 patients (65%) the symptoms were due to non-biliary pathology. In this group ultrasound detected the actual site of pathology in 28%. Ultrasonography which can image multiple organs rapidly is a useful initial screening procedure in patients presenting with acute right upper quadrant pain because it can detect the actual size of pathology in about two-thirds of the cases.
    Matched MeSH terms: Malaysia
  11. Fulltext Medical problems in an oil palm estate
    Chua WT, Lim CH
    Family Practitioner, 1982;5(3):49-53.
    Oil palm estates and associated industries employ a fair proportion of workers. Good medical care benefits both the employers and the employees. The pattern of illness is not very different from that found in general practice. However, certain environmental factors, the nature of occupation and the water supply can influence the increased incidence of certain diseases. Upper respiratory tract infection, acute gastroenteritis, contact dermatitis (eczemas & rashes) eye, and ear diseases, injuries and musculoskeletal diseases are the commonest causes of morbidity. The resident doctor, who has a good knowledge of the environment of his patients is in the best position to practise preventive medicine or early intervention, thereby reducing illnesses and improving productivity of the workers.
    Matched MeSH terms: Malaysia
  12. Fulltext Unplanned pregnancies in a semi-urban practice
    Chua WT
    Family Practitioner, 1985;8(2):57-62.
    One hundred and twenty-four women from a semi-urban area who came for consultation for unplanned pregnancy during an eight month period are analysed. It is found that women with a high risk of unplanned pregnancy are mostly housewives, aged between 20 and 34, who have given birth to one or three children, the last of whom is usually below one or two years old. They belong to the lower socio-economic class and are lowly-educated. Most of them have not completed their families. Although most of them have either used or heard of contraceptives begore, the majority were not using any contraceptive at the time of consultation or were using an ineffective method. Their reasons for non-use or default are identified, many of which are related to the pill. Proper motivation of would-be contraceptive receptors and regular follow-up of acceptors by general practitioners or Family Planning Clinic Staff who are knwoledgable in all available methods of contraception are offered as a solutionto the problem of high rate of defaulting and consequent high rate of unplanned pregnancies.
    Study site: private general practice clinic, Perak, Malaysia
    Matched MeSH terms: Malaysia
  13. Health Technology Assessment in Malaysia: Past, Present, and Future
    Roza S, Junainah S, Izzuna MMG, Ku Nurhasni KAR, Yusof MAM, Noormah MD, et al.
    Int J Technol Assess Health Care, 2019;35(6):446-451.
    PMID: 30864531 DOI: 10.1017/S0266462319000023
    OBJECTIVES: The aim of this study was to provide a comprehensive overview of the evolution of health technology assessment (HTA) in Malaysia over the past decade.

    METHODS: We described the evolution of HTA program in Malaysia based on review of administrative data, publicly available information and quantitative description of impact evaluation.

    RESULTS: Health Technology Assessment HTA was formalized in Malaysia in 1995 as a central structure within the Ministry of Health, Malaysia in 1995. Expansion of activities demonstrated over the years including Horizon Scanning of health technologies and implementation of evidence-based Clinical Practice Guidelines. Improvement on the processes in terms of types of report, quality, monitoring, and impact evaluation as well as accessibility was also carried out. Examples of impact/influence of the reports have also been demonstrated.

    CONCLUSIONS: HTA program in Malaysia has evolved over the past decades. Its role in policy formulation and decision making of health technologies has become more significant over the years and is foreseen to be bigger in the future. As a trusted source of evidence, HTA in Malaysia will continue to strengthen the health system by advocating informed decision making and value-based medicine. As other countries in this region is trying to establish their own HTA processes and procedures, this review on the evolution of the HTA program in Malaysia might give some insights on developing a sustainable HTA program.

    Matched MeSH terms: Malaysia
  14. Fulltext The Malacca Strait separates distinct faunas of poorly-flying Cautires net-winged beetles
    Jiruskova A, Motyka M, Bocek M, Bocak L
    PeerJ, 2019;7:e6511.
    PMID: 30863675 DOI: 10.7717/peerj.6511
    We investigated the spatial and temporal patterns of Cautires diversification on the Malay Peninsula and Sumatra to understand if the narrow and frequently dry Malacca Strait separates different faunas. Moreover, we analyzed the origin of Cautires in Malayan and Sumatran mountains. We sampled 18 localities and present the mtDNA-based phylogeny of 76 species represented by 388 individuals. The phylogenetic tree was dated using mtDNA evolution rates and the ancestral ranges were estimated using the maximum likelihood approach. The phylogeny identified multiple lineages on the Malay Peninsula since the Upper Eocene (35 million years ago, mya) and a delayed evolution of diversity in Sumatra since the Upper Oligocene (26 mya). A limited number of colonization events across the Malacca Strait was identified up to the Pliocene and more intensive faunal exchange since the Pleistocene. The early colonization events were commonly followed by in situ diversification. As a result, the Malacca Strait now separates two faunas with a high species-level turnover. The montane fauna diversified in a limited space and seldom took part in colonization events across the Strait. Besides isolation by open sea or a savannah corridor, mimetic patterns could decrease the colonization capacity of Cautires. The Malay fauna is phylogenetically more diverse and has a higher value if conservation priorities should be defined.
    Matched MeSH terms: Malaysia
  15. Fulltext The potential of pumpkin (cucurbita moschata duschene) as commercial crop in malaysia
    Aimi Adzirul kamarubahrin, Asmaddy Haris, Siti Nurazira Mohd Daud, Zurina kefeli @ Zulkefli, Nursilah Ahmad, Nurul Aini Muhamed, et al.
    The Pertanika Journal of Scholarly Research Reviews, 2018;4(3):1-10.
    MyJurnal
    Awareness of recommendations for fruit and vegetable consumption has increased substantially over the last 20 years. In addition, fruits and vegetables such as pumpkin (Cucurbita moschata Duchesne) are good sources of many important nutrients, including potassium, vitamin C, folate, fibre, and numerous phytochemicals. Malaysia produces pumpkinits own, with considerably large areas of production comparable to its high global demand. However, in reality, there is a limitation in the commercial production as the local pumpkinis very much dependent on the market demand as the utilization has been limited to the consumption of fresh product. Thus, the objective of the study first initiative to provide the information about the pumpkinand second to investigatesthe opportunities on commercialized local pumpkinin Malaysia as by products despite various nutritious it is also listed as prophetic foods. The scientific research that covered a broad range of in vitro to in vivo studies on the by-products potentials of these fruits is also discussed in detail.The current review is an update for researchers to have a better understanding of the pumpkin, which simultaneously can provide awareness to enhance their commercial value and promote their utilization.Malaysia have potential to growth pumpkin instead of continuously importing. The daily consumption of pumpkins may provide various health benefits to human. Future investigation is needed to explore the potential of pumpkin as by products in order to increase its competitiveness and self-sufficiency.
    Matched MeSH terms: Malaysia
  16. Fulltext Datasets of essential oils from naturally formed and synthetically induced Aquilaria malaccensis agarwoods
    Abdul Kadir FA, Azizan KA, Othman R
    Data Brief, 2020 Feb;28:104987.
    PMID: 32226799 DOI: 10.1016/j.dib.2019.104987
    Agarwood is the highly valuable fragrant resin of the wounded Aquilaria spp. trees widely used in fragrances, medicines and incenses. Among the Aquilaria spp., A. malaccensis is the primary producer and is mainly found in Indonesia and Malaysia. In normal condition, agarwood is naturally formed in Aquilaria trees as a defense mechanism upon physical damage or microbial infection on the trees, which is a slow process that occurs over several years. The high demand in agarwood has spurred the development of various artificial inoculation methods where agarwood formation is synthetically induced in a shorter period of time. However, the synthetic induction method produces agarwood with aromas different from the naturally formed agarwood. To understand the changes in the agarwoods produced from different induction conditions, metabolite profiling of agarwood essential oil from A. malaccensis has been performed. The essential oils of healthy undamaged tree trunks and, naturally formed and synthetically induced agarwoods were obtained using hydrodistillation (HS) method and analysed using gas chromatography mass spectrometer (GC-MS). These data will provide valuable resources for chemical components of agarwood produced by the species in the genus Aquilaria.
    Matched MeSH terms: Malaysia
  17. Sea water shaping the freshwater biota: Hidden diversity and biogeographic history in the Paracanthocobitis zonalternans species complex (Teleostei: Nemacheilidae) in western Southeast Asia
    Bohlen J, Dvořák T, Šlechta V, Šlechtová V
    Mol Phylogenet Evol, 2020 07;148:106806.
    PMID: 32247884 DOI: 10.1016/j.ympev.2020.106806
    Western Southeast Asia is hosting one of the world's most diverse faunas, and one of the reasons for this huge diversity is the complex geologic past of the area, increasing the frequency of isolation and expansion events over evolutionary time scale. As an example case, the present study reveals the phylogeny and biogeographic history of the Paracanthocobitis zonalternans species complex, small benthic freshwater fish (Teleostei: Nemacheilidae) that are commonly occurring across western Southeast Asia (from central Myanmar through western and southern Thailand to northern Malaysia). The group is particularly interesting since it occurs in three biogeographic subdivisions (Indian, Indochinese, Malay/Sundaic) and across all of the major biogeographic barriers in the region. Basing on mitochondrial and nuclear sequence data of 93 samples from about 50 localities we found six major clades, most with exclusive geographic distribution. Divergence time dated the origin of the P. zonalternans species complex to early Miocene (17.8 MYA) and a biogeographic analysis identified the Tenasserim region as the ancestral region. From this region the fish spread during periods of lowered global sea level, particularly during late Miocene (11-8 MYA) northwards into all Burmese river basins and southwards into south Thailand and northern Malaysia. Besides lowered global sea level periods, local stream capture events allowed the complex to expand, e.g. into the Mae Klong basin. Strong fragmentations during periods with elevated sea level during the Pliocene and Pleistocene repeatedly restricted populations to refuges and shaped the observed major lineages. Our results document a higher diversity within the P. zonalternans species complex than formerly believed and a strong impact of global sea level on its evolutionary history. Low sea levels promoted dispersal and elevated sea levels fragmentation events. A very similar impact of sea level changes can be expected in all stationary fauna (freshwater and terrestrial) in all non-mountainous coastal regions worldwide.
    Matched MeSH terms: Malaysia
  18. Characterization of slowly-biodegradable organic compounds and hydrolysis kinetics in tropical wastewater for biological nitrogen removal
    How SW, Sin JH, Wong SYY, Lim PB, Mohd Aris A, Ngoh GC, et al.
    Water Sci Technol, 2020 Jan;81(1):71-80.
    PMID: 32293590 DOI: 10.2166/wst.2020.077
    Many developing countries, mostly situated in the tropical region, have incorporated a biological nitrogen removal process into their wastewater treatment plants (WWTPs). Existing wastewater characteristic data suggested that the soluble chemical oxygen demand (COD) in tropical wastewater is not sufficient for denitrification. Warm wastewater temperature (30 °C) in the tropical region may accelerate the hydrolysis of particulate settleable solids (PSS) to provide slowly-biodegradable COD (sbCOD) for denitrification. This study aimed to characterize the different fractions of COD in several sources of low COD-to-nitrogen (COD/N) tropical wastewater. We characterized the wastewater samples from six WWTPs in Malaysia for 22 months. We determined the fractions of COD in the wastewater by nitrate uptake rate experiments. The PSS hydrolysis kinetic coefficients were determined at tropical temperature using an oxygen uptake rate experiment. The wastewater samples were low in readily-biodegradable COD (rbCOD), which made up 3-40% of total COD (TCOD). Most of the biodegradable organics were in the form of sbCOD (15-60% of TCOD), which was sufficient for complete denitrification. The PSS hydrolysis rate was two times higher than that at 20 °C. The high PSS hydrolysis rate may provide sufficient sbCOD to achieve effective biological nitrogen removal at WWTPs in the tropical region.
    Matched MeSH terms: Malaysia
  19. Fulltext Dataset of reptiles in fragmented forests at Tasik Kenyir, Hulu Terengganu, Malaysia
    Komaruddin SA, Mohamad NA, Fatihah-Syafiq M, Badli Sham BH, Mamat MA, Zakaria N
    Data Brief, 2020 Feb;28:104994.
    PMID: 32226800 DOI: 10.1016/j.dib.2019.104994
    This data article is about reptiles (lizard, snake, and skink) captured from fragmented forest within man-made lake of Tasik Kenyir that is situated in Terengganu State, Peninsular Malaysia. Data collection was conducted in January 2019 and sampling methods included drift fenced-pitfall traps and Visual Encounter Survey (VES). All animals were identified, measured snout to vent (SVL) and weighted before their release at the site of capture. The highlights like conservation statuses in the wild, detection type and substrate type are presented with the data to increase its value. A total of 73 individuals from 18 species, 15 generas and seven families of reptiles were recorded. The data comprised of seven reptile family groups Agamidae, Gekkonidae, Scincidae, Colubridae, Elapidae, Viperidae and Homalopsidae. Reptiles like Cyrtodactylus quadrivirgattus (n = 33, 45.2%) and Aphaniotis fusca (n = 7, 9.6%) were most dominant in the checklist and most of the animals were captured using VES. Data of SVL and mass of the animals can be further interpreted by researchers to assess the health condition of animals in the altered habitats.
    Matched MeSH terms: Malaysia
  20. New insights into the haplotype diversity of the cosmopolitan cat flea Ctenocephalides felis (Siphonaptera: Pulicidae)
    Azrizal-Wahid N, Sofian-Azirun M, Low VL
    Vet Parasitol, 2020 May;281:109102.
    PMID: 32289653 DOI: 10.1016/j.vetpar.2020.109102
    The present study investigated the genetic profile of the cosmopolitan cat flea, Ctenocephalides felis (Siphonaptera: Pulicidae) from Malaysia and the reference data available in the National Center for Biotechnology Information (NCBI) GenBank. A set of sequences of 100 Malaysian samples aligned as 550 characters of the cytochrome c oxidase subunit I (cox1) and 706 characters of the II (cox2) genes revealed ten haplotypes (A1-A10) and eight haplotypes (B1-B8), respectively. The concatenated sequences of cox1 and cox2 genes with a total of 1256 characters revealed 15 haplotypes (AB1-AB15). Analyses indicated that haplotype AB1 was the most frequent and the most widespread haplotype in Malaysia. Overall haplotype and nucleotide diversities of the concatenated sequences were 0.52909 and 0.00424, respectively, with moderate genetic differentiation (FST = 0.17522) and high gene flow (Nm = 1.18). The western population presented the highest genetic diversity (Hd = 0.78333, Pi = 0.01269, Nh = 9), whereas the southern population demonstrated the lowest diversity (Hd = 0.15667, Pi = 0.00019, Nh = 3). The concatenated sequences showed genetic distances ranged from 0.08 % to 4.39 %. There were three aberrant haplotypes in cox2 sequences that highly divergent, suggesting the presence of cryptic species or occurrence of introgression. In the global point of view, the aligned sequences of C. felis revealed 65 haplotypes (AA1-AA65) by the cox1 gene (n = 586), and 27 haplotypes (BB1-BB27) by the cox2 gene (n = 204). Mapping of the haplotype network showed that Malaysian C. felis possesses seven unique haplotypes in both genes with the common haplotypes demonstrated genetic affinity with C. felis from Southeast Asia for cox1 and South America for cox2. The topologies of cox1 and cox2 phylogenetic trees were concordant with relevant grouping pattern of haplotypes in the network but revealed two major lineages by which Malaysian haplotypes were closely related with haplotypes from the tropical region.
    Matched MeSH terms: Malaysia
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