Displaying publications 6721 - 6740 of 24636 in total

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  1. Cheah WL, Chang CT, Helmy H, Wan Manan WM
    Malays Fam Physician, 2019;14(3):46-54.
    PMID: 32175040
    Introduction: Physical inactivity is the one of the leading causes of major non-communicable diseases in the world. The aim of this study is to assess the feasibility of an intervention program based on the stages of change, physical activity levels and health profiles of selected overweight and obese adults in Sarawak.

    Methods: This intervention study was carried out using selected overweight and obese adults in Sarawak. A total of 75 participants were placed in the intervention group, and 80 respondents were placed in the control group participated. Respondent-determined weekly aerobic exercise sessions were conducted for six months. The Malay version of the long-form International Physical Activity Questionnaire (IPAQ) and Transtheoretical model of change (TTM) questionnaire were used, together with anthropometric measurements and the collection of venous fasting blood profiles. Data was entered and analyzed using SPSS Version 20.

    Results: The intervention group had significant better stage transitions compared to the control group (p<0.01). They also had significantly lower total cholesterol, although both groups showed significant results (difference= 0.53, p<0.01; difference= 0.38, p=0.01). The respondent-determined intervention program was effective in improving stage transition; however, an intervention of longer duration could provide more conclusive health outcomes.

    Conclusion: Physical activity plays a role in assisting overweight and obese adults to be more active and healthier.

    Matched MeSH terms: Malaysia
  2. Afiq Ramlee MN, Hussin MF, Roslan A, Rosmidi FH, Pesiu E, Aisyah A Rahim N, et al.
    Data Brief, 2020 Apr;29:105328.
    PMID: 32181296 DOI: 10.1016/j.dib.2020.105328
    This data article presents the diversity of flora and selected fauna in Tasik Kenyir, Malaysia. This man-made lake once suffered huge loss of biodiversity for allowing an earth-dam construction during 1980s. Series of publications on different types of target taxa have been published separately after the post-dam construction. A biodiversity assessment was conducted in Tasik Kenyir from March 2015 until February 2016. The one year assessment were compiled with the previous published data to document and updated the biodiversity checklist in the lake. The data show that Tasik Kenyir is occupied by 113 tree species, 217 butterfly species, 35 bee species, 26 reptile species, 267 aves species and 153 mammal species. The micro-climate data was downloaded from the Malaysian Meteorological Department and analysed in R Studio to highlight the relationship between climate data and biodiversity data.
    Matched MeSH terms: Malaysia
  3. Aziz F, Malek S, Mhd Ali A, Wong MS, Mosleh M, Milow P
    PeerJ, 2020;8:e8286.
    PMID: 32206445 DOI: 10.7717/peerj.8286
    Background: This study assesses the feasibility of using machine learning methods such as Random Forests (RF), Artificial Neural Networks (ANN), Support Vector Regression (SVR) and Self-Organizing Feature Maps (SOM) to identify and determine factors associated with hypertensive patients' adherence levels. Hypertension is the medical term for systolic and diastolic blood pressure higher than 140/90 mmHg. A conventional medication adherence scale was used to identify patients' adherence to their prescribed medication. Using machine learning applications to predict precise numeric adherence scores in hypertensive patients has not yet been reported in the literature.

    Methods: Data from 160 hypertensive patients from a tertiary hospital in Kuala Lumpur, Malaysia, were used in this study. Variables were ranked based on their significance to adherence levels using the RF variable importance method. The backward elimination method was then performed using RF to obtain the variables significantly associated with the patients' adherence levels. RF, SVR and ANN models were developed to predict adherence using the identified significant variables. Visualizations of the relationships between hypertensive patients' adherence levels and variables were generated using SOM.

    Result: Machine learning models constructed using the selected variables reported RMSE values of 1.42 for ANN, 1.53 for RF, and 1.55 for SVR. The accuracy of the dichotomised scores, calculated based on a percentage of correctly identified adherence values, was used as an additional model performance measure, resulting in accuracies of 65% (ANN), 78% (RF) and 79% (SVR), respectively. The Wilcoxon signed ranked test reported that there was no significant difference between the predictions of the machine learning models and the actual scores. The significant variables identified from the RF variable importance method were educational level, marital status, General Overuse, monthly income, and Specific Concern.

    Conclusion: This study suggests an effective alternative to conventional methods in identifying the key variables to understand hypertensive patients' adherence levels. This can be used as a tool to educate patients on the importance of medication in managing hypertension.

    Matched MeSH terms: Malaysia
  4. Masseran N, Mohd Safari MA
    J Environ Manage, 2020 Jun 15;264:110429.
    PMID: 32217317 DOI: 10.1016/j.jenvman.2020.110429
    Intensity-duration-frequency (IDF) curves can serve as useful tools in risk assessment of extreme environmental events. Thus, this study proposes an IDF approach for evaluating the risk of expected occurrences of extreme air pollution as measured by an air pollution index (API). Hourly data of Klang city in Malaysia from 1997 to 2016 are analyzed. For each year, a block maxima size is determined based on four different monsoon seasons. Generalized extreme value (GEV) distribution is used as a model to represent the probabilistic behavior of maximum intensity of the API, which is derived from each block. Based on the GEV model, the IDF curves are developed to estimate the extreme pollution intensities that correspond to various duration hours and return periods. Considering the IDF curves, we found that for any duration hour, the magnitude of pollution intensity tends to be high in parallel with increasing return periods. In fact, a high-intensity pollution event that poses a high risk of affecting the environment is less frequent than low-intensity pollution. In conclusion, the IDF curves provide a good basis for decision makers to assess the expected risk of extreme pollution events in the future.
    Matched MeSH terms: Malaysia
  5. Ambigapathy S, Rajahram GS, Shamsudin UK, Khoo EM, Cheah WK, Peariasamy KM, et al.
    Malays Fam Physician, 2020;15(1):2-5.
    PMID: 32284798
    The COVID-19 outbreak continues to evolve with the number of cases increasing in Malaysia, placing a significant burden on general practitioners (GPs) to assess and manage suspected cases. GPs must be well equipped with knowledge to set up their clinics, use Personal Protective Equipment (PPE) appropriately, adopt standard protocols on triaging and referrals, as well as educate patients about PPE. The correct use of PPE will help GPs balance between personal safety and appropriate levels of public concern.
    Matched MeSH terms: Malaysia
  6. Alkhadher SAA, Kadir AA, Zakaria MP, Al-Gheethi A, Asghar BHM
    Mar Pollut Bull, 2020 May;154:111115.
    PMID: 32319929 DOI: 10.1016/j.marpolbul.2020.111115
    The current study aimed to develop a suitable molecular marker [Linear alkylbenzenes (LABs)] approach for pollution determination in mangrove oysters of peninsular Malaysia. C. belcheri species were collected from rivers of Merbok, Perai, Klang, Muar and PulauMerambong (An Island). The LABs were extracted from C. belcheri and determined using GC-MS. The LABs indices which included I/E, L/S and C13/C12 were applied to describe the sources and biodegradation of LABs. The results revealed that the maximum concentrations were detected in oysters from Klang (27.91 ng g-1dw), while the lowest concentrations were detected in oysters from Merbok (8.12 ng g-1dw). Moreover, I/E ratios varied between 2.83 and 6.40, indicating the secondary treatment effluents being discharged to coastal zones. The results of this study suggested that the oysters absorbed LABs mainly in dissolved phase. Therefore, mangrove oysters are a good biosensor for LABs contamination in the aquatic environment.
    Matched MeSH terms: Malaysia
  7. Husam IS, Abuhamad, Azuraliza Abu Bakar, Suhaila Zainudin, Mazrura Sahani, Zainudin Mohd Ali
    Sains Malaysiana, 2017;46:255-265.
    Dengue fever is considered as one of the most common mosquito borne diseases worldwide. Dengue outbreak detection can be very useful in terms of practical efforts to overcome the rapid spread of the disease by providing the knowledge to predict the next outbreak occurrence. Many studies have been conducted to model and predict dengue outbreak using different data mining techniques. This research aimed to identify the best features that lead to better predictive accuracy of dengue outbreaks using three different feature selection algorithms; particle swarm optimization (PSO), genetic algorithm (GA) and rank search (RS). Based on the selected features, three predictive modeling techniques (J48, DTNB and Naive Bayes) were applied for dengue outbreak detection. The dataset used in this research was obtained from the Public Health Department, Seremban, Negeri Sembilan, Malaysia. The experimental results showed that the predictive accuracy was improved by applying feature selection process before the predictive modeling process. The study also showed the set of features to represent dengue outbreak detection for Malaysian health agencies.
    Matched MeSH terms: Malaysia
  8. F. Shaari, Mustapha MA
    Sains Malaysiana, 2017;46:1191-1200.
    Determination of chlorophyll-a (Chl-a) distribution in the coastal waters is important to understand the coastal environmental conditions. This study was conducted to understand the spatial and temporal distribution of Chl-a along coastal waters of east Peninsular Malaysia and factors influencing its variability using Chl-a data derived from Aqua MODIS satellite (1 km spatial resolution) from January 2006 to December 2012. Chl-a variability was described using empirical orthogonal function (EOF) analysis. In-situ data (temperature, salinity, density and nitrate) and rainfall data from the Department of Meteorology were analyzed using spatial interpolation to determine factors influencing the distribution of Chl-a. The seasonal progressions of Chl-a showed high value during northeast monsoon along the coast. This variability was described by four modes of the EOF analysis. The first mode (72.08% of total variance) indicated seasonal cycle with high variability along the coast. Second mode (17.03% of variance) explained the northeast monsoon with high variability from river mouth to the south. Third mode (2.39% of variance) indicated variability during southwest monsoon along the coast and much higher to the south. Mode 4 (1.93% of variance) explained the inter-monsoon period observed along the northern and southern coastline. Concentration and distribution of Chl-a were related to availability of nutrient influenced by rainfall. The thermohaline front was also observed to play an important role in accumulation of phytoplankton biomass during northeast and southwest monsoon.
    Matched MeSH terms: Malaysia
  9. Marina Zainal Abidin, Ahmad Abas Kutty, Tukimat Lihan, Nurul Akhma Zakaria
    Sains Malaysiana, 2018;47:1401-1411.
    This study attempts to assess the impact of various types of land use along Sungai Langat and describes hydrological
    change and water quality variation along this river. This study also determines water quality of Sungai Langat based on
    low flow dry period Q100,7 using the application of QUAL2K. Dissolved oxygen (DO), pH, temperature and conductivity
    were measured in situ. Biochemical oxygen demand (BOD5
    ), ammonia nitrogen (NH3
    -N) and total suspended solid (TSS)
    were analysed according to the standard methods (APHA). Water quality data was referred to National Water Quality
    Standards for Malaysia (NWQS) proposed by Malaysian Department of Environment (DOE) to estimate Sungai Langat
    water quality status. Four important water quality parameters namely DO, BOD5, NH3
    -N and TSS were simulated with
    QUAL2K version 2.07 for 83.67 km. As regard to individual parameter, DO classified this river into class III, BOD5 in
    Class II, NH3
    -N in Class IV and TSS in Class I. Based on QUAL2K simulation for low flow scenario, the results clearly
    demonstrates a gradually reduction of DO and BOD5 whereas NH3
    -N and TSS display opposite. Only NH3
    -N was found
    significantly increase which cause low water quality class towards the downstream. Three parameters namely DO, BOD5
    and NH3
    -N show effects of industrial which approximately located at the middle of river stretch. The TSS was contributed
    to the river system at the upstream and downstream of the river stretch which most likely from sand mining activity which
    located at Sungai Long, Cheras (near R5) and Sungai Semenyih (R11).
    Matched MeSH terms: Malaysia
  10. Vanoh D, Shahar S, Razali R, Ali NM, Manaf ZA, Mohd Noah SA, et al.
    J Alzheimers Dis, 2019;70(s1):S255-S270.
    PMID: 31256116 DOI: 10.3233/JAD-180464
    BACKGROUND: Intervention strategies, especially online based approaches, are considered to be beneficial in improving the health of the senior. The effectiveness of such approaches is yet to be determined.

    OBJECTIVE: This study aims to determine the effectiveness of the web-based application, WESIHAT 2.0©, for improving cognitive function, physical fitness, biochemical indices, and psychosocial variables among older adults in Klang Valley, Malaysia. The cost analysis of WESIHAT 2.0© was also determined.

    METHOD: The study utilized a two-arm randomized controlled trial with 25 subjects in each of the intervention and control groups. The participants chosen for the study included those who were 60 years and above with at least secondary education and had internet access using a computer at home. The intervention group was exposed to the website (30 minutes per day, 4 days per week) for six months, while the control group was given health education pamphlets. Activity-Based Costing method was used to determine the cost saved using WESIHAT 2.0© as compared to using the pamphlet.

    RESULTS: Significant intervention effects were observed for self-perception of disability and informational support scores. WESIHAT 2.0© was able to save costs in improving the self-perception of disability score and the informational support score at MYR 6.92 and MYR 13.52, respectively, compared to the conventional method.

    CONCLUSION: WESIHAT 2.0© was able to save costs in improving the self-perceived disability and informational support scores for the intervention group.

    Matched MeSH terms: Malaysia
  11. Zulkifli A, Khairul Anuar A, Atiya AS, Yano A
    JUMMEC, 1999;4:99-103.
    A survey of malnutrition and helminth infections among 268 pre-school children living in the Kuala Betis Orang Asli resttlement villages in Kelantan. The prevalence of helminth infections was 47.4% with Ascaris lumbricoides being the most common helminth (43.9%), followed by Trichuris trichiura (29.7%) and hookworm (6.3%). The prevalence of Ascaris lumbricoides and Trichuris trichiura infections increased with age, with the highest prevalence found in the 6-7 years age group. The overall prevalence of stunting, underweight and wasting were 61.7%, 60.4% and 17.5% respectively. Both stunting and underweight were significantly higher among the infected children. Factors associated with helminth infections in the pre-school children were older age group, poor water supply and households with more than 5 members. Rountine regular deworming is recommended based on the World Health Organisation recommendations for school children.
    Matched MeSH terms: Malaysia
  12. Teh BT, Wan Azman WA, Thuraisingham S, Choy AM, Tan KH, Jesudason P, et al.
    JUMMEC, 1999;4:26-33.
    Activation of the synlpathetic nervous system (SNS) and renin-angiotensin system (RAS) plays a pivotal role in the pathophysiology and progression of the disease in chronic heart failure (CHF). Blocking the activation of the RAS with angiotensin converting enzyme inhibitors not only improves sylnptonls but also prolongs life in symptomatic CHF. Does a similar analogy hold true for the use of ß-blockers in CHF? Evidence from a number of small trials and several recent large prospective trials show that b-blockers may improve ventricular function and symptoms in CHF. In a combination of trials investigating the use of carvedilol (an α, and ß-blocker) in congestive heart failure a mortality benefit appears to be evident. There are still a number of key questions that relnaill unanswered regarding the tolerability, patient type and stage of CHF in which ß-blockers should be advocated. Several large scale trials are in progress to answer some of these questions and also to add further information regarding its efficacy and impact on survival. KEYWORDS: Beta-adrenoreceptor antagonist, congestive heart failure.
    Matched MeSH terms: Malaysia
  13. El-Sabban F, Zariah A, Murgan V
    JUMMEC, 2000;5:17-23.
    The use of brain slice preparatiotis has become ilicreasiligly popular among scientists of different disciplines in recent decades for the study of the mammalian central nervous system (CNS) in general and of synaptic phenomena in particular. The in vitro hippocampal slice may be the single most used preparation, among other slices of different parts of the brain areas. The use of brain slices in different experimental work offers certain advantages over the in vivo approaches to the study of the CNS; however, such preparations may have some limitations. This review describes the hippocampal slice technique, explores some of the different types of studies in which it was employed and points out the advantages and limitations of its use. KEYWORDS: Hippocalnpal slices, brain slices, technique, synaptic function, electrophysiology, in vitvo.
    Matched MeSH terms: Malaysia
  14. Ong BB, Krishnan R, Lee P
    JUMMEC, 2000;5:33-35.
    Head injury contributes to a significant proportion of motorcycle fatalities. The site and pattern of head injury in victims of fatal motorcycle crashes in 1995 were studied retrospectively. The site of impact on the head was determined based on the injuries on the scalp, pattern of skull fractures and injuries of the brain. Of 54 cases, 9 had massive crush injuries. Of the remaining 45 cases, the site of impact was as follows: frontal 21, lateral 14, posterior 4, vertex 1, chin 1 and unascertainable in 4 cases. The majority of injuries occurred on the front and lateral aspects of the skull. Motorcycle helmets are currently tested for impact energy attenuation and penetration test at the vertex. Helmet standards need to take into account site and nature of injury. KEYWORDS: Head injury, motorcycle fatalities, helmet standards.
    Matched MeSH terms: Malaysia
  15. Fathilah B, Mahmood AA, Sidik K, Salma I
    JUMMEC, 2005;8:28-32.
    Six groups of adult male Sprague Dawley rats, each consisting of six animals were used throughout the experiment. The gastroprotective effects of aqueous plant extract alone, honey alone or honey in combination with ethanolic or aqueous extracts of A. conyzoides and cimetidine were investigated in rats against ethanol-HClinduced gastric ulcer. Efficacy was assessed by determination of ulcer index and inhibition percentage. Oral administration of ethanol-HCl (5 ml kg-1 body weight) to fasted rats produced extensive lesions of gastric mucosa (Group 1). Pre-treatment with honey (2.5 g kg-1 body weight) alone (Group 2), aqueous plant extract alone (10% w/v 5 ml kg-1) (Group 3), or honey in combination with each of alcoholic extract (10% w/w 5 ml kg-1) (Group 4), aqueous extract (10% w/w 5 ml kg-1) (Group 5) or cimetidine (10 mg/ml honey 5 ml kg-1) (Group 6) orally 30 minutes before administration of absolute ethanol-HCl significantly (p < 0.05) protected gastric lesions by 46.74%, 61.50%, 76.68%, 78.39% and 56.55% respectively. Although the mechanism of gastric protection is unknown, honey in combination with each plant extract appears to increase the resistance of gastric mucosal cells to the necrotizing effect of strong irritants in the absolute ethanol-HCl mixture. The results suggest that honey in combination with each plant extract might be beneficial in the treatment of a variety of diseases in which gastric mucosal injury is present. KEYWORDS: Honey, A. conyzoides, cimetidine, rats, ulcer
    Matched MeSH terms: Malaysia
  16. Siti Norazah Z
    JUMMEC, 2002;7(1):15-23.
    Reproductive health is "a state of complete, mental and social well-being in all matters relating to the reproductive system and to its functions and processes. Implicit in this is the right of men and women to be informed and to have access to safe, effective and affordable and acceptable methods of family planning of their choice, as well as other methods of their choice for regulation of fertility, which are not against the law, and the right of access to health-care services that enable women to go safely through pregnancy and childbirth." The survey on Health Problems of Migrant Workers included a section on Women's Health covering aspects of reproductive health. This was based on concerns over reproductive health needs of migrant women workers, particularly since the large majority are in the reproductive age-group, and the utilisation of government healthcare facilities. The latter has implications for the potential burden on public healthcare services in terms of resources and costs. Specifically, the Women's Health section included questions on pregnancy, place of delivery of last baby (born in Malaysia), postnatal care related to this delivery, and mode of payment. For those currently pregnant, questions were asked of sources of antenatal care, postnatal care and respective modes of payment for thsoe services. This section also included questions on current contraceptive practices, source of supplies, and mode of payment for contraceptive methods.
    Matched MeSH terms: Malaysia
  17. Ong SQ
    Sains Malaysiana, 2016;45:777-785.
    Dengue is a major issue in Malaysia as the dramatic emerge of infection. Yet an effective vaccine or medicine is not
    yet available, although many attempts are undergoing. Dengue vector control is still considered the most effective way
    for controlling and preventing the transmission of dengue virus. Nonetheless, as the conventional approaches are less
    successful in managing the dengue transmission, it is time to review the current applied and other available approaches.
    Current dengue vector relied greatly on the chemical approach as space treatment either thermal or ULV fogging, however,
    the approach seem like under the expectation. Beside space treatment, new control methods for example biological
    control (bacterium Bacillus thuringiensis, predatory mosquito Toxorhynchites) and attractive trap were carried out
    at certain location of Malaysia. Moreover, new emerged approaches such as mass release of genetic modification or
    artificially Wolbachia infected male dengue vector for the objective of generating sterile offspring when mate with
    wild population is urge to be tested in Malaysia, although concerns have to be taken before the actual mass release. In
    conclusion, control of dengue vector shall not consist exclusively for a single approach, neither genetic modification
    of artificially Wolbachia infected technique, nor the conventional insecticidal treatment. It should, however, comprise
    of the environment management as the fundamental approach, a well-planned integrated control program and a good
    cooperation among the organization.
    Matched MeSH terms: Malaysia
  18. Nor Azah Samat, Syafiqah Husna Mohd Imam Ma’arof
    Sains Malaysiana, 2016;45:1741-1745.
    Disease frequency is used to measure the situation of the disease with reference to the population size and time period
    which is in a fractional form. The lower part of the fraction, known as denominator is the important part as it was used
    to calculate a rate or ratio. Since the disease frequency is based on a ratio estimator, the results are highly dependent
    upon the value of denominator. Therefore, the main aim of this paper was to propose a new method in calculating the
    denominator for the relative risk equation with the application to chikungunya disease data from Malaysia. The new
    method of calculating the denominator of the relative risk equation includes the use of discrete time-space stochastic
    SIR-SI (susceptible-infective-recovered for human population and susceptible-infective for vector population) disease
    transmission model instead of the total disease counts. The results of the analysis showed that the estimation of expected
    disease counts based on total posterior means can overcome the problem of expected counts estimation based on the total
    number of disease especially when there is no observed disease count in certain regions. The proposed new approach to
    calculate the denominator for the relative risk equation is suitable for the case of rare disease in which it offers a better
    method of expected disease counts estimation.
    Matched MeSH terms: Malaysia
  19. Choo YM
    Sains Malaysiana, 2017;46:1581-1586.
    Crotalaria pallida Aiton is an herbaceous legume from the family Fabaceae. In the present study, one new cyclopentyliene, crotolidene (1) and seven known compounds, i.e. hydroxydihydrobovolide (2), octacosane (3), trans-phytyl palmitate (4), linoleic acid (5), methyl oleate (6), ethyl palmitate (7), and palmitic acid (8) were isolated from the C. pallida collected from Perak, Malaysia. These compounds were isolated and characterized using extensive chromatographic and spectroscopic methods.
    Matched MeSH terms: Malaysia
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