Displaying publications 81 - 100 of 188 in total

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  1. Galadima AN, Mohd Zulkefli NA, Said SM, Ahmad N, Garba SN
    PLoS One, 2022;17(12):e0263436.
    PMID: 36480545 DOI: 10.1371/journal.pone.0263436
    BACKGROUND: Childhood immunisation coverage is very low in Nigeria (31%) with Zamfara State being amongst the states with the poorest coverage (<10%). Lack of maternal knowledge, attitude, outcome expectations, self-efficacy, cultural beliefs and assumptions of religious regulations of antenatal mothers towards childhood immunisation are the contributory factors to poor childhood immunisation uptake. This study aims is to develop, implement and evaluate the effects of an immunisation health educational intervention with application of Social Cognitive Theory on pregnant women to improve knowledge, attitude, outcome expectations, self-efficacy, cultural beliefs and assumptions on religious regulations regarding childhood immunization uptake in Federal Medical Centre Gusau, Zamfara State, Nigeria.

    METHODOLOGY: The study will be a single-blind parallel-group randomised controlled trial, where baseline data will be collected from 392 estimated antenatal mothers, after that they will be evenly randomised using randomly generated permuted block sizes (each containing two intervention and two control assignments). The study participants will be antenatal mothers of ages 18 years and above who are in third trimesters and attending Federal Medical Centre Gusau, Zamfara State, Nigeria; during the study period and fulfilled all the inclusion and exclusion criteria. The intervention group will undergo five-health education sessions on immunisation, which will be strictly guided by Social Cognitive Theory-based intervention module: while the control group will receive usual care (standard care). Follow-up data will be collected using the same questionnaire at 6-weeks post-delivery, 10-weeks post-delivery and 14-weeks post-delivery. The generalized linear mixed model will be carried-out to determine the overall effect of the intervention after controlling for 14 potential confounding variables. An intention to treat analysis will also be carried-out. Childhood immunisation uptake is the primary outcome while the secondary outcomes are: improved knowledge scores, attitude scores, outcomes expectation, self-efficacy scores, cultural beliefs scores and assumptions on religious regulations scores.

    DISCUSSION: The study will be a randomised controlled trial, that focuses on the effects of an immunisation health educational intervention with application of Social Cognitive Theory on pregnant women to improve knowledge, attitude, outcome expectations, self-efficacy, cultural beliefs and assumptions on religious regulations regarding childhood immunisation uptake in Federal Medical Centre Gusau, Zamfara State, Nigeria.

    TRIAL REGISTRATION: Pan African Clinical Trial Registry PACTR202006722055635. Protocol registered on 09 June 2020.

    Matched MeSH terms: Nigeria
  2. Olonade OY, Adetunde CO, Iwelumor OS, Ozoya MI, George TO
    Heliyon, 2021 Mar;7(3):e06451.
    PMID: 33786389 DOI: 10.1016/j.heliyon.2021.e06451
    Introduction: The coronavirus pandemic outbreak is wreaking much havoc across the globe, with many nations shutting down their economy and social life with the hope of flattening the curve while health practitioners are also gearing efforts in providing a cure for it. Part of the coronavirus challenges is the various spiritual undertones attributed to it in many quarters. Hence, this study seeks to understand the various spiritual undertones attributed to the coronavirus incidence in southwest Nigeria.

    Methodology: This paper examined the coronavirus pandemic and spirituality sociologically in southwest Nigeria, using secondary and primary data. Secondary data includes a review of literature, social media comments, official records, and newspaper reports. Primary data entails using google form (questionnaire) circulated via social media with 221 responses retrieved and analyzed using the frequency distribution tables and bar charts. Also, a one-sample t-test was used for further statistical analysis.

    Results: Findings show that rather than attributing coronavirus incidence to spirituality alone, most of the respondents also see it as a public health concern, and precautionary measures should adhere. They see the government ban on social gathering, which affected the religious houses as the right thing to do and not solely targeted as religious houses. However, most believe that religious houses provide 'essential' emotional and spiritual support to the people. Respondents also believe they can get their healing from their place of worship even if infected with the coronavirus.

    Conclusion: Based on the findings it was recommended that religious organizations should source valid data so that policy-makers can make informed decisions. Also, there is a need to have an accurate record of the number of infected persons and death rates to know the right time to ease lockdown and lift the social gathering measures. There should also be a place for easy and free testing for people. This will help the government ascertain the number of infected persons, reduce the associated fear with the pandemic, and lessen the people's economic, social, and religious effects.

    Matched MeSH terms: Nigeria
  3. Chen Y, Maidin SS, Tsegyu S, Tiamiyu KA, Ogbonne IP, Yare DM, et al.
    PLoS One, 2023;18(11):e0292640.
    PMID: 37917609 DOI: 10.1371/journal.pone.0292640
    The researchers in Study 1 conducted interviews among experts and developed a small group communication programme to be delivered in 24 months. In Study 2, a quasi-experiment was conducted involving 540 smallholder farmers in Nigeria to test the impact of the developed programme. The result showed that smallholder farmers with art skills who received the small group communication programme reported a significant improvement in their entrepreneurial competence and economic self-efficacy compared to smallholder farmers who did not receive the programme. A follow-up assessment after two years revealed the steady effectiveness of the developed programme.
    Matched MeSH terms: Nigeria
  4. Griffiths DA
    Can J Microbiol, 1966 Feb;12(1):149-63.
    PMID: 5923132
    Matched MeSH terms: Nigeria
  5. Lavelle CL, Flinn RM, Foster TD, Hamilton MC
    J Anat, 1970 Jul;107(Pt 1):182-3.
    PMID: 5473274
    Matched MeSH terms: Nigeria
  6. Abubakar AR, Chedi BA, Mohammed KG, Haque M
    J Adv Pharm Technol Res, 2015 Oct-Dec;6(4):154-8.
    PMID: 26605155 DOI: 10.4103/2231-4040.165021
    Spontaneous reporting (SPR) and intensive monitoring are the conventional systems used for detecting, recording, and reporting adverse drug reactions (ADRs). Using spontaneous reporting a lot of successes has been made as existing ADRs were identified and new ones prevented through this methods. The aim of this appraisal was to evaluate the knowledge, attitude, and the practice of medical students with regards to ADRs reporting and to see if differences exist between the level of study and genders. The questionnaire was adopted, modified, and validated from previous studies. It comprised of 25 questions. It was administered year-IV and V medical students of Bayero University Kano, Nigeria. The data collected were coded and analyzed using the Statistical Package for the Social Sciences (SPSS) version 20, currently known as IBM SPSS Statistics. The response rate was 74%. Among the 108 participants, 80% got the definition of ADRs correct; 63% of them knew the precise functions of pharmacovigilance (PV). In addition, 82% strongly agreed that ADR reporting is health care workers responsibility; 82% also said PV should be taught in detail. Meanwhile, 99% have noticed patient experiencing ADRs; 67% said even mild ADRs should be reported. The outcome of this study showed good knowledge and attitude with respect to ADRs and PV among the medical students surveyed. Unfortunately, the practice of medical students was found to be unsatisfactory. There is a need to upgrade the students teaching the curriculum with respect to ADRs monitoring.
    Matched MeSH terms: Nigeria
  7. Abubakar AR, Ismail S, Rahman NI, Haque M
    Ther Clin Risk Manag, 2015;11:1015-25.
    PMID: 26170680 DOI: 10.2147/TCRM.S85019
    BACKGROUND: Internationally, there is a remarkable achievement in the areas of drug discovery, drug design, and clinical trials. New and efficient drug formulation techniques are widely available which have led to success in treatment of several diseases. Despite these achievements, large number of patients continue to experience adverse drug reactions (ADRs), and majority of them are yet to be on record.
    OBJECTIVES: The purpose of this survey is to compare knowledge, attitude, and practice with respect to ADRs and pharmacovigilance (PV) between medical students of Malaysia and Nigeria and to determine if there is a relationship between their knowledge and practice.
    METHOD: A cross-sectional, questionnaire-based survey involving year IV and year V medical students of the Department of Medicine, Universiti Sultan Zainal Abidin and Bayero University Kano was carried out. The questionnaire which comprised 25 questions on knowledge, attitude, and practice was adopted, modified, validated, and administered to them. The response was analyzed using SPSS version 20.
    RESULTS: The response rate from each country was 74%. There was a statistically significant difference in mean knowledge and practice score on ADRs and PV between medical students of Malaysia and Nigeria, both at P<0.000. No significance difference in attitude was observed at P=0.389. Also, a statistically significant relationship was recorded between their knowledge and practice (r=0.229, P=0.001), although the relationship was weak.
    CONCLUSION: Nigerian medical students have better knowledge and practice than those of Malaysia, although they need improvement. Imparting knowledge of ADRs and PV among medical students will upgrade their practice and enhance health care delivery services in the future.
    KEYWORDS: KAP; Malaysia; Nigeria; drug safety; medical students; underreporting
    Matched MeSH terms: Nigeria
  8. Ibrahim A, Haruna JA
    The study investigated the effects of flipped and conventional classroom teaching approach on performance and retention ability of advance financial accounting students in Abubakar Tafawa Balewa University Bauchi, Nigeria. The study had three specific objectives and three null hypotheses. Quasiexperimental design of pre-test, post-test I and post-test II was used for the study. The study used an intact class of 76 students that offered advance financial accounting in 2015/2016 academic session in the institution. Three instruments were used for data collection. The instruments were Advance financial accounting Achievement Test (AFAAT), Advance financial accounting Diagnostic Achievement Test I (AFADAT I) and Advance financial accounting Diagnostic Achievement Test II (AFADAT II). The validations of instruments were determined by board of examiners in department of vocational and technology education in Abubakar Tafawa Balewa University, Bauchi. The reliability of the instruments was established using pilot study. The result of the pilot study gave reliability coefficient of 0.79. Data collected from the study were coded into Statistical Package of Social Sciences. The package was used to run t-test statistics for the test of the three null hypotheses at significance level of 0.05. The results shows improvement in the performance and retention ability of students when flipped teaching technique was adopted. It was recommended among others that financial accounting lecturers in Nigerian universities should adopt the use of flipped classroom approach in teaching students by providing students with pre-class materials and assignments prior their classroom activities.
    Matched MeSH terms: Nigeria
  9. Muhammed A, Khuan L, Shariff-Ghazali S, Said SM, Hassan M
    Midwifery, 2019 Jun;73:62-68.
    PMID: 30884373 DOI: 10.1016/j.midw.2019.03.004
    OBJECTIVE: Planned home birth may increase women's access to skilled midwives in all settings. Using theory to understand and predict midwives' intention regarding planned home birth services is rare. Therefore, using the theory of planned behaviour, we determined the factors associated with midwives' intention to provide planned home birth services to low-risk women.

    DESIGN: This cross-sectional study adopted a quantitative approach and a survey. Stratified random sampling was used to recruit 226 midwives in Sokoto, Nigeria. Data-including descriptive statistic and multiple linear regression analyses-were analysed using SPSS 23 and significant was set at 0.05.

    SETTING: Ten public health facilities in Sokoto, northwestern Nigeria.

    PARTICIPANTS: Among all 460 midwives (women aged 20-60 years), working in the maternity wards of health facilities in Sokoto, a sample of 226 midwives was calculated using a power of 0.80 and a 95% confidence interval.

    FINDINGS: The multiple linear regression analyses confirmed that the major factors associated with midwives' intention to provide planned home birth services were midwives' attitude towards planned home birth (p < .001) and midwives' previous experience with planned home birth practice (p = .008).

    CONCLUSIONS AND IMPLICATIONS: The theory of planned behaviour is a useful framework for identifying factors that affect midwives' intention to provide planned home birth services. While future research may employ a qualitative approach to explore other factors, planned home birth education campaigns should target information that enhances positive attitude and encourages midwives to provide planned home birth services.

    Matched MeSH terms: Nigeria
  10. Abakpa GO, Umoh VJ, Kamaruzaman S, Ibekwe M
    J Sci Food Agric, 2018 Jan;98(1):80-86.
    PMID: 28543177 DOI: 10.1002/jsfa.8441
    BACKGROUND: Some routes of transmission of Escherichia coli O157:H7 to fresh produce include contaminated irrigation water and manure polluted soils. The aim of the present study was to determine the genetic relationships of E. coli O157:H7 isolated from some produce growing region in Nigeria using enterobacterial repetitive intergenic consensus (ERIC) DNA fingerprinting analysis. A total of 440 samples comprising leafy greens, irrigation water, manure and soil were obtained from vegetable producing regions in Kano and Plateau States, Nigeria. Genes coding for the quinolone resistance-determinant (gyrA) and plasmid (pCT) coding for multidrug resistance (MDR) were determined using polymerase chain reaction (PCR) in 16 isolates that showed MDR.

    RESULTS: Cluster analysis of the ERIC-PCR profiles based on band sizes revealed six main clusters from the sixteen isolates analysed. The largest cluster (cluster 3) grouped isolates from vegetables and manure at a similarity coefficient of 0.72.

    CONCLUSION: The present study provides data that support the potential transmission of resistant strains of E. coli O157:H7 from vegetables and environmental sources to humans with potential public health implications, especially in developing countries. © 2017 Society of Chemical Industry.

    Matched MeSH terms: Nigeria
  11. Olatunji MA, Khandaker MU, Nwankwo VUJ, Idris AM
    Radiat Environ Biophys, 2022 Nov;61(4):597-608.
    PMID: 36175773 DOI: 10.1007/s00411-022-00993-3
    Proper documentation of baseline radiation data of different environments is an important step toward adequate environmental monitoring, and it provides quick means to quantitatively check and determine possible radionuclide contamination by anthropogenic sources. Besides, such documentation is useful for decision making processes, assessment of dose rates to the public, epidemiological studies, and environmental regulations. This review summarizes the results of studies conducted on radioactivity in Nigerian environments. For most soil samples, the levels of radioactivity are well within the world averages of 33, 45, and 420 Bq kg-1 for 226Ra, 232Th and 40K, respectively. Other soil samples from regions such as Abeokuta in the southwest, and Jos in the northcentral have been described as high background radiation areas with radioactivity values comparable with those obtained from known high background radiation areas such as the Odisha (formerly Orissa) coast in India (with values reported as 350, 2,825, and 180 Bq kg-1 for 238U/226Ra, 232Th, and 40K, respectively). In some parts of Nigeria, surface and underground water sources used for drinking and other purposes also present elevated levels of 226Ra above the world range of 0.01 to 0.1 Bq l-1 and the tolerable levels recommended by the World Health Organization and U.S. Environmental Protection Agency. Corresponding radiation doses due to measured radioactivities from different environments were estimated and compared with those reported in similar studies around the world. More so, the human and environmental health hazards that might be associated with the reported radioactivity in different environmental settings are discussed. The present report is expected to support authorities in developing appropriate regulations to protect the public from radiation exposure arising from environmental radioactivity. The report also examines other areas of consideration for future studies to ensure adequate radiation monitoring in Nigeria.
    Matched MeSH terms: Nigeria
  12. Saidu AS, Mohammed S, Adamu SG, Sadiq MA, Tijjani AO, Musa HI, et al.
    Sci Rep, 2023 Dec 27;13(1):23079.
    PMID: 38155194 DOI: 10.1038/s41598-023-49451-0
    Cryptosporidium is one of the most important protozoan parasitic pathogens, and it is a common cause of diarrhoea in humans, domestic animals, and wild vertebrates and has serious public health threats. A cross-sectional study was designed to determine the prevalence of Cryptosporidium oocysts in raw-eaten vegetables in Maiduguri Metropolitan Council (MMC) and Jere Local Government Areas (LGAs). A total of 400 samples were collected from four (4) different locations, namely Tashan Bama, Gomboru, and Monday Markets (n = 100), while fifty (n = 50) each from 202-Vegetable-Vendors and Unimaid Commercials. A total of 16 visits were conducted in all the sampling areas (twenty-five samples per visit). The Cryptosporidium oocysts were detected using the Modified Ziehl-Neelsen Staining Technique. The locations, sources, and types of raw-eaten vegetables were also assessed. The oocysts were confirmed (100×) as bright pink spherules. Data generated were analyzed using IBM-SPSS V23.0, and p ≤ 0.05 was considered significant. Out of the total samples (n = 400) analyzed, cabbage appeared to have the highest number of 10 (12.5%) of Cryptosporidium oocysts detected, while Tomato and garden egg had 9 (11.3%) and 1 (1.2%), respectively. There was a statistically significant association (χ2 = 12.5, P = 0.014) between the presence of Cryptosporidium oocysts in raw-eaten vegetables and vegetable types. Among the sources of the vegetables sampled, Alau had the highest number of Cryptosporidium oocysts, 15 (12.5%), followed by Kilari-Abdullahi and Zabarmari sources with 4 (10.0%) and 4 (5.0%), respectively. However, Jetete appeared to have the least number 2 (2.5%) of oocysts, and there was a statistically significant association (χ2= 10.4, P = 0.034) between the presence of Cryptosporidium oocysts and the sources of vegetables and fruits. The study concludes that the raw-eaten vegetables sampled from Maiduguri Metropolis were contaminated with Cryptosporidium oocysts. The study recommends that all raw-eaten vegetables should be from cleaned sources and washed before consumption. Consumers should be enlightened on the hygienic measures in the food chain in line with the Hazard Analysis and Critical Control Points (HACCP) principles.
    Matched MeSH terms: Nigeria/epidemiology
  13. Tee GH, Aris T, Rarick J, Irimie S
    Asian Pac J Cancer Prev, 2016;17(3):1269-76.
    PMID: 27039759
    BACKGROUND: Tobacco consumption continues to be the leading cause of preventable deaths globally. The objective of this study was to examine the associaton of selected socio-demographic variables with current tobacco use in five countries that participated in the Phase II Global Adult Tobacco Survey in 2011 - 2012.

    MATERIALS AND METHODS: We analysed internationally comparable representative household survey data from 33,482 respondents aged ≥ 15 years in Indonesia, Malaysia, Romania, Argentina and Nigeria for determinants of tobacco use within each country. Socio-demographic variables analysed included gender, age, residency, education, wealth index and awareness of smoking health consequences. Current tobacco use was defined as smoking or use of smokeless tobacco daily or occasionally.

    RESULTS: The overall prevalence of tobacco use varied from 5.5% in Nigeria to 35.7% in Indonesia and was significantly higher among males than females in all five countries. Odds ratios for current tobacco use were significantly higher among males for all countries [with the greatest odds among Indonesian men (OR=67.4, 95% CI: 51.2-88.7)] and among urban dwellers in Romania. The odds of current tobacco use decreased as age increased for all countries except Nigeria where. The reverse was true for Argentina and Nigeria. Significant trends for decreasing tobacco use with increasing educational levels and wealth index were seen in Indonesia, Malaysia and Romania. Significant negative associations between current tobacco use and awareness of adverse health consequences of smoking were found in all countries except Argentina.

    CONCLUSIONS: Males and the socially and economically disadvantaged populations are at the greatest risk of tobacco use. Tobacco control interventions maybe tailored to this segment of population and incorporate educational interventions to increase knowledge of adverse health consequences of smoking.

    Matched MeSH terms: Nigeria/epidemiology
  14. Dawaki S, Al-Mekhlafi HM, Ithoi I
    Trans R Soc Trop Med Hyg, 2019 04 01;113(4):169-182.
    PMID: 30551211 DOI: 10.1093/trstmh/try128
    BACKGROUND: Parasitic infections constitute a major public health problem worldwide, particularly among underprivileged communities in developing countries including Nigeria. The present study aimed to determine the epidemiology of polyparasitism (multiple parasitic infections) among rural communities in Kano State, North Central Nigeria.

    METHODS: A total of 551 individuals were screened for the presence of intestinal, urogenital and blood parasites by using different diagnostic techniques. Demographic, socioeconomic, household and behavioural characteristics were collected using a pre-tested questionnaire.

    RESULTS: Overall, 84.0% (463/551) of the participants were found to be infected with at least one parasite species, with 51.2% (282/551) of them having polyparasitism. The most prevalent parasites were Plasmodium falciparum (60.6%) followed by Blastocystis sp. (29.2%) and hookworm (15.4%). No significant association was found between malaria and helminth infections (p>0.05). Univariate and multivariate analyses showed that the presence of other family members who had intestinal polyparasitism (adjusted odds ratio [AOR]=4.12; 95% CI=2.72, 6.24), walking barefoot outside (AOR=1.70; 95% CI=1.09, 2.63) and being male (AOR=1.74; 95% CI=1.14, 2.66) were the significant risk factors of intestinal polyparasitism among the population studied.

    CONCLUSION: Polyparasitism is highly prevalent among rural communities in Kano State. Therefore, effective, sustainable and integrated control measures should be identified and implemented to significantly reduce the burden and consequences of these infections in rural Nigeria.

    Matched MeSH terms: Nigeria
  15. Hamza AM, Al-Sadat N, Loh SY, Jahan NK
    Biomed Res Int, 2014;2014:350281.
    PMID: 24982864 DOI: 10.1155/2014/350281
    This study aims to identify the predictors in the different aspects of the health-related quality of life (HRQoL) and to measure the changes of functional status over time in a cohort of Nigerian stroke survivors. A prospective observational study was conducted in three hospitals of Kano state of Nigeria where stroke survivors receive rehabilitation. The linguistic-validated Hausa versions of the stroke impact scale 3.0, modified Rankin scale, Barthel index and Beck depression inventory scales were used. Paired samples t-test was used to calculate the amount of changes that occur over time and the forward stepwise linear regression model was used to identify the predictors. A total of 233 stroke survivors were surveyed at 6 months, and 93% (217/233) were followed at 1 year after stroke. Functional disabilities were significantly reduced during the recovery phase. Motor impairment, disability, and level of depression were independent predictors of HRQoL in the multivariate regression analysis. The involvement of family members as caregivers is the key factor for those survivors with improved functional status. Thus, to enhance the quality of poststroke life, it is proposed that a holistic stroke rehabilitation service and an active involvement of family members are established at every possible level.
    Matched MeSH terms: Nigeria/epidemiology
  16. Sararaks S, Jamaluddin R
    Med J Malaysia, 1997 Sep;52(3):257-63.
    PMID: 10968095
    A cross sectional study was carried out in Negeri Sembilan to identify factors associated with job satisfaction of doctors serving in Ministry of Health and their intentions to resign. All Ministry of Health doctors currently working in Negeri Sembilan were included in the study and data collection was done via a self-administered postal questionnaire. The response rate was 69.4%. Out of those who responded, only 31.3% had global job satisfaction, with the majority dissatisfied. Intention to resign was high among 32.7% of the respondents. Factors found to be significantly associated with job satisfaction were age, job designation, income, duration of service and intention to resign. Intention to resign was found to be significantly associated with ethnicity and income. From logistic regression, predictors of job satisfaction identified were age, place of first graduation, and satisfaction with status and autonomy, satisfaction with career development, satisfaction with workload and satisfaction with transfers. Predictors of intention to resign were race, income and global job satisfaction.
    Matched MeSH terms: Nigeria
  17. Mustapha A, Aris AZ, Ramli MF, Juahir H
    PMID: 22702815 DOI: 10.1080/10934529.2012.680415
    The pollution status of the downstream section of the Jakara River was investigated. Dissolved oxygen (DO), 5-day biochemical oxygen demand (BOD(5)), chemical oxygen demand (COD), suspended solids (SS), pH, conductivity, salinity, temperature, nitrogen in the form of ammonia (NH(3)), turbidity, dissolved solids (DS), total solids (TS), nitrates (NO(3)), chloride (Cl) and phosphates (PO(3-)(4)) were evaluated, using both dry and wet season samples, as a measure of variation in surface water quality in the area. The results obtained from the analyses were correlated using Pearson's correlation matrix, principal component analysis (PCA) and paired sample t-tests. Positive correlations were observed for BOD(5), NH(3), COD, and SS, turbidity, conductivity, salinity, DS, TS for dry and wet seasons, respectively. PCA was used to investigate the origin of each water quality parameter, and yielded 5 varimax factors for each of dry and wet seasons, with 70.7 % and 83.1 % total variance, respectively. A paired sample t-test confirmed that the surface water quality varies significantly between dry and wet season samples (P < 0.01). The source of pollution in the area was concluded to be of anthropogenic origin in the dry season and natural origins in the wet season.
    Matched MeSH terms: Nigeria
  18. Garba NN, Abdulkadir M, Nasiru R, Saleh MA, Bello S, Khandaker MU, et al.
    Isotopes Environ Health Stud, 2023 Mar;59(1):112-125.
    PMID: 36735938 DOI: 10.1080/10256016.2023.2172001
    Terrestrial gamma radiation dose (TGRD) rates were measured in situ from different locations in Katsina State, Nigeria, using a portable radiation survey metre based on geological formations and soil types. The measured TGRD rates ranged from 45 to 271 nGyh-1 with an average value of 116 ± 1 nGyh-1. Geological formation (silicified sheared rock) and soil type (lithosols and ferruginous crusts and ferruginous tropical soils) appeared to have the highest mean TGRD values of 163 and 134 nGyh-1 with sandstone geological formation and alluvial and hydromorphic soils having the lowest TGRD with values of 80 and 61 nGyh-1, respectively. One way ANOVA results shows that the tested null hypothesis was rejected. Thus, indicating that there exists a strong relationship between the various geological formations, soil types with the measured TGRD values based on the alternate hypothesis. Human health hazard indices like annual effective dose equivalent (AEDE), lifetime outdoor annual equivalent dose, and relative excess lifetime outdoor cancer risk associated with the mean TGRD of the study area were also calculated and found to be 0.711, 9.955 mSv, and 5.79 × 10-4, respectively. These values were higher than the world average values but favourable compared with the safety limits recommended by ICRP.
    Matched MeSH terms: Nigeria
  19. Emeka LB, Emeka PM, Khan TM
    Pak J Pharm Sci, 2015 Nov;28(6):1985-90.
    PMID: 26639493
    Microbial resistance to existing antibiotics has led to an increase in the use of medicinal plants that show beneficial effects for various infectious diseases. The study evaluates the susceptibility of multidrug resistant Staphylococcus aureus to Nigella sativa oil. Staphylococcus aureus was isolated from 34 diabetic patient's wounds attending the Renaissance hospital, Nsukka, Southeast Nigeria. The isolates were characterized and identified using standard microbiological techniques. Isolates were cultured and a comparative In vitro antibiotic susceptibility test was carried out using the disk diffusion method. Of the 34 samples collected, 19(56%) showed multidrug resistance to the commonly used antibiotics. Nigella sativa oil was then studied for antibacterial activity against these multidrug resistant isolates of Staphylococcus aureus in varying concentration by well diffusion method. The oil showed pronounced dose dependent antibacterial activity against the isolates. Out of 19 isolates, 8(42%) were sensitive to undiluted oil sample; 4(21%) of these showed sensitivity at 200 mg/ml, 400 mg/ml and 800 mg/ml respectively. Eleven (58%) of the isolates were completely resistant to all the oil concentrations. The present study, reports the isolation of multi-drug resistant S. aureus from diabetic wounds and that more than half of isolates were susceptible to different concentrations N. sativa oil.
    Matched MeSH terms: Nigeria
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