Objective: The present study aims to assess verbal memory performance in patients with schizophrenia attending HUSM and determine the relationship between the patients’ verbal memory performance and their demographic/clinical factors. Methods: A cross sectional study of 114 patients with schizophrenia attending HUSM psychiatric services from December 2007 to May 2008 was conducted. The schizophrenia symptoms as well as verbal memory performance were assessed using the Brief Psychiatric Rating Scale, the Malay version of the Calgary Depression Scale (MVCDS), and the Malay version of the Auditory Verbal Learning Test (MVAVLT). The relationship between verbal memory performance and demographic/clinical symptoms was evaluated using Pearson Correlation. Results: Overall MVAVLT scores in all the trials were lowered in patients with schizophrenia compared to average healthy controls. There were significant relationships between occupational status and MVAVLT performance in Trial A1-A5 Total; between educational level and MVAVLT performance in Trial A1 and Trial A1-A5 Total and between severities of illness and MVAVLT performance in all indexes except Trial A1 after controlled for occupation and
educational level. Conclusions: Patient with schizophrenia in HUSM performed significantly worse than healthy controls in verbal memory with or without interference. There were significant relationships between MVAVLT performance and patient’s occupational s tatus, educational level and severity of the illness but not depressive symptoms.
Study site: Hospital Universiti Sains Malaysia (HUSM)
To ensure the reliability of manual blood pressure (BP) readings in a clinical trial, sources of error due to measurement must be reduced as much as possible. Apart from following standard procedure for BP measurement and ensuring good equipments, the measurement errors that come from the assessors themselves should be assessed. Objective: To demonstrate the use of two-way random effects, interactions absent, absolute agreement (Type A), single measures (Type 1) intraclass correlation coefficient (ICC) in the assessment of reliability of manual BP readings among assessors involved in a clinical trial using manual BP measurement, by using an interrater reliability study conducted by the authors as an example study. Methods: The steps involved in obtaining ICC in the study were discussed. Sample size given the number of assessors in the study was calculated. BP was measured using regularly maintained mercury sphygnomanometers, following recommendations by Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) for BP measurement in office setting. The outcomes were systolic and diastolic BP readings. A type of ICC, two-way random effects, interactions absent, absolute agreement (Type A), single measures (Type 1) ICC was chosen for the analysis and specifically discussed. Pre-requisite assumptions for ICC were meticulously checked and described. The interrater reliability for systolic and diastolic BP readings as expressed by ICC (single measure) were presented with confidence interval (CI). The ICCs obtained in the example study were discussed and concluded. The flaws of the study were also criticised. Results: The interrater reliability for systolic and diastolic BP measurements as expressed by ICC (single measure) were 0.87 (95% confidence interval [CI] 0.722, 0.956) and 0.77 (95% CI 0.560, 0.918) respectively. Conclusion: We demonstrated the steps required to obtain ICC. Since the use of manual BP measurement using mercury sphygmomanometer is still considered as gold standard of BP measurement, it is important that studies in which the BP outcome is measured using such method conduct interrater reliability studies properly.
Objective: To determine the incidence and predictors of early ankle contracture in adults with acquired brain injury. Methods: A prospective cohort study of patients admitted to Neurosurgical Intensive Care Unit (NICU), University Malaya Medical Centre and referred for rehabilitation within a period of 12 months. Adult patients with newly diagnosed acquired brain injury with no prior deformity to lower limbs, Glasgow Coma Scale ≤ 12, no concomitant spinal or lower limb injuries, medical stability at inclusion into the study and agreed to participate for the total duration of assessment (3 months) were recruited. We conducted weekly review of ankle muscle tone and measurement of ankle maximum passive dorsiflexion motion. The end point is reached if ankle contracture developed or completed 3 months post injury assessment. Results: The cohort included 70 patients, of which only 46 patients completed the study. Twenty-eight patients suffered from severe brain injury whilst 18 from moderate brain injury. Out of the 46 patients, 13 (28%) developed ankle contracture at the end of the study period. Abnormal motor pattern was significantly associated with incidence of ankle contracture, which included spasticity (p
The electrical resistivity and flexural strength of plastic composites reinforced with pineapple leaf particles (PCPLP) is presented. PCPLP were produced using different plastic materials; Polyethylene (PE) and Polypropylene (PP), and different plastic pineapple leaf particle ratios; 50:50 and 70:30. The PCPLP were tested and evaluated with respect to electrical resistivity and flexural strength according to ASTM D257 and D790, respectively. The results indicate that PCPLP made from PP exhibits better electrical resistance than PE, which may be attributed to the better frequency insulation behaviour ofPP. PCPLP using the higher ratio of 70:30 also exhibited better electrical resistance than the lower 50:50 ratio. Cellulose materials inherently influence the electrical resistance of plastic composites, due to their natural propensity to absorb moisture. The PCPLP produced using a ratio of 50:50 for both PP and PE composites exhibited better MOE results than the 70:30 composites, however the converse is true with respect to the MOR. MOE of PCPLP was increased with increasing pineapple leaf particles content due to the greater matrix stiffness of this natural particle with respect to plastic matrix. However, high percentage offiller particles in the matrix (70:30 ratio) has reduced the toughness in the composite structure due to the lost ofphysical contact between high accumulated particles.
Changes to the physicochemical properties of wheat, sago and tapioca starches subjected to gamma ray, electron beam and microwave irradiations and the conditions that lead to wheat starch having leaching behaviour similar to sago or tapioca starch were studied. The properties were characterised through swelling and leaching behaviours of the starch granules and retrogradation following pasting. The leaching of wheat starch increased tremendously and resulted in amylose to amylopectin ratios in the leachate similar to that of native sago and tapioca starches. This observation is significant as wheat starch is known to have a leachate composition of mostly amylose. This opens up the possibility of utilising wheat starch in snacks where tapioca and sago starch are commonly used. It was observed that the required conditions for such changes were exposure to microwave for 8 and 10 minutes, electron beam at 5 and 10 kGy and gamma ray at 5 kGy.
Developments of computer technology and image processing have shifted conventional industrial radiography application to industrial digital radiography (IDR) system. In this study, two types of IDR modules for non destructive testing (NDT), namely drum- and laser- type film digitizer with 50 μm pixel pitch have been evaluated for NDT applications. The modulation transfer function (MTF) and noise power spectrum (NPS) measurement were adapted to evaluate the image quality of IDR images. Results shown the averaged MTF for drum- and laser- type film digitizer at 20% modulation were 6.15 cycles/mm and 6.55 cycles/mm respectively. For NPS measurement and calculation, the result obtained shows that drum type film digitizer produced higher noise then laser type film digitizer. The study shows that the laser type film digitizer is the best system to be used for film digitization purposes because the MTF result shows that it modulates better than drum type and has the lowest and stable NPS.
At present, soil and mineral based building material such as bricks are one of the main components in building construction in Malaysia. This building material is a direct source of radiation exposure since it contains naturally occurring radioactive materials (NORM). In this study, clay brick samples used were obtained from 7 factories in Selangor and Johore, Malaysia. The activity concentrations of 226 Ra, 232 Th and 40 K in these samples of clay bricks were determined using a comparative method and was analysed using gamma spectrometry with HPGe detector. The mean values of activity concentrations for 226 Ra, 232 Th and 40 K were found to be in the range of 39.04 ± 0.88 Bqkg-1 - 73.61 ± 5.32 Bqkg-1, 43.38 ± 2.60 Bqkg-1 - 73.45 ± 1.51 Bqkg-1, and 381.54 ± 11.39 Bqkg-1 - 699.63 ± 15.82 Bqkg-1, respectively. The radiation hazard of NORM in the samples was estimated by calculating the radium equivalent activity (Raeq), external hazard index (Hex) and internal hazard index (Hin). Radium equivalent activity (Raeq) determined was in the range of 151.90 Bqkg-1 - 194.22 Bqkg-1 which is lower than the limit of 370 Bqkg-1 (equivalent to 1.5 mSvyr-1 ) recommended in the NEA-OECD report in 1979, whereas external hazard index (Hex) and internal hazard index (Hin) were between 0.20 – 0.26 and 0.52 - 0.71 respectively. The annual effective dose rate exposure to a dweller received from the clay bricks was calculated to be in the range of 0.35 ± 0.18 mSvy-1 - 0.43 ± 0.09 mSvy-1.
Concentrations of Natural Occurring Radioactive Material (NORM) and terrestrial gamma radiation have been shown to be associated with certain lithology and soil types. An attempt was made to statistically predict and validate environmental gamma radiation dose rates based on limited number of actual field measurements using sodium iodide (NaI(Tl)) detector. Statistical analysis including the correlations between the actual and predicted dose were made based on 32 different lithology and soil type combinations. Results of field measurements, have shown that more than 50% of the predicted data were not significantly different from the actual measured data. The interpolation method in GIS was used to produce an isodose map based on the prediction equation. A correlation of multiple regression on the predicted versus lithology and soils dose rates gave relationships of DP = 0.35 DL + 0.82 DS – 0.02, r2 = 0.736. A predicted isodose map was subsequently plotted base on 4 dose rates classes, ranging from 0.1 – 0.3 μSvhr-1.
Elliptic curve cryptosystems (ECC) provides better security for each bit key utilized compared to the RSA cryptosystem. For this reason, it is projected to have more practical usage than the RSA. In ECC, scalar multiplication (or point multiplication) is the dominant operation, namely, computing nP from a point P on an elliptic curve, where n is an integer defined as the point resulting from adding P + P + ... + P, n times. However, for practical uses, it is very important to improve the efficiency of the scalar multiplication. Solinas (1997) proposes that the τ-adic Non-Adjacent Form (τ-NAF) is one of the most efficient algorithms used to compute scalar multiplications on Anomalous Binary curves. In this paper, we give a new property (i.e., Theorem 1.2) of τ-NAF(n) representation for every length, l. This is useful for evaluating the maximum and minimum norms occurring among all length-l elements of Z(τ). We also propose a new cryptographic method by using randomization of a multiplier n to nr an element of Z(τ). It is based on τ-NAF. We focused on estimating the length of RTNAF(nr) expansion by using a new method.
The aim of this project is to produce electricity from citronella biomass using isolated microbes from wastewater as biocatalyst in a dual chamber microbial fuel cell (MFC). MFC is one such system that not only reduced biomass, which contains mostly waste products but can also liberate electricity from them. MFC system is well-established and using lignocellulosic biomass as fuel is one step to future energy generation. Trials of MFC experiments have been conducted but using citronella bagasse (CB) as fuel source. Furthermore, pre-treatment of the biomass was done using NaOH pre-treament and effluent treatment wastewater from a palm edible oil company as a source for microorganism. The end results indicate that bioelectricity production from CB is possible though very low yield in the present MFC.
The present study was aimed at assessing the effect of solvents on the yield and the color properties of amaranth extract. Two species of amaranth namely Amaranthus gangeticus and Amaranthus blitum were extracted with water, methanol and ethanol. Seven parameters like betacyanin content, total soluble solids, lightness (L*), redness (a*), yellowness (b*), hue angle (h*) and chroma (c*) were analyzed to assess extraction efficiency. Correlation analysis was carried out to assess the linear association among the analytical variables. Principal component analysis was used to establish the relationships between the different analytical variables and to detect the most important factors of variability. Among the two varieties, Amaranthus gangeticus extract contained about two and half time more betacyanin with half of total soluble solids compared to Amaranthus blitum. Water is the best as solvent for extracting betacyanin from Amaranthus gangeticus and ethanol in case of Amaranthus blitum. Among the analytical parameters, a* and c* were perfectly correlated. Three principal components were found among the seven analytical variables accounting 88% of total variability. The first principal components mostly reflected the redness (a*), whereas the second principal components reflected the betacyanin content, total soluble solids and lightness (L* value).
The abdominal pelvic cavity has always been regarded as one of the most vulnerable regions of the body. Injuries to this part have been known to be very serious. Based on this a retrospective study was performed on postmortem cases with abdominal and pelvic trauma from 1 October 2002 to 31 January 2003 at the Forensic Institute, Hospital Kuala Lumpur to determine the common pattern of abdomino-pelvic injuries, the injury’s relationship to epidemiological and socio-economic factors, risk organ within the abdominopelvic region and relationship between injuries and survival period. A total of 122 cases abdomino-pelvic were obtained stemming from medico legal postmortems procedures. Results indicated that those aged between 21 to 30 years (38.5%) had the highest incidence of this type of injury. Categorization based on gender showed that males (90.2%) dominated most of the cases. Prevalence based on socio-economic status showed that lower socioeconomy class (52.5%) had the highest incident. This was followed by the middle income (39.3%) and finally the higher income group. The most numerous type of trauma was non-penetrating trauma (94.3%). It was also found that victims with low injury severity score (ISS) had a longer survival period as compared to those with high ISS. It was also noted that victims with two or more region injuries either were spot dead or brought dead. The most common combination of injuries was abdomen, pelvic, chest and limb. In most blunt trauma cases majority of victims had one or two organ involvement while penetrating injuries were difficult to asses. The most common organ involved in this type of trauma was liver (72.1%), pelvic bone (47.5%) and spleen (43.4%). In conclusion, abdomino-pelvic injury is a serious condition and should not be overlooked. Proper attention towards their diagnosis and management is important and so any patient of head injury with coma must be considered as having intra-abdominal injury until proven otherwise.
The present study was carried out to determine the concentrations of selected metal elements (lead, copper, manganese, zinc and iron) in 51 samples of commercial drinking water and tap water available in Malaysia. The results indicated that low metal elements were found in the studied water samples. Lead, manganese, zinc and iron were not detected in some of the studied samples, except copper. The concentrations of the metal elements in the studied samples were well below the maximum permitted concentrations as recommended. Therefore these drinking water are safe for consumption and do not pose adverse effect to the health of consumers due to metal toxicity.
Kajian terdahulu banyak menunjukkan perbezaan dalam dimensi okular mengikut kaum. Walau bagaimanapun hanya terdapat sedikit data mengenai dimensi okular bangsa Melayu di Malaysia yang dilaporkan. Kajian ini bertujuan untuk menetapkan nilai normal dimensi okular bangsa Melayu muda di Malaysia. Seramai 584 orang telah diundang untuk menjadi subjek untuk kajian secara sukarela. Pengukuran yang dilakukan meliputi kelengkungan dan ketebalan tengah kornea, nilai esentrisiti kornea (e), diameter iris horizontal dan vertikal yang kelihatan, saiz pupil dan bukaan palpebral. Subjek dibahagikan kepada 3 kumpulan berikut mengikut umur dan dipadankan mengikut jantina dan umur: Kumpulan 1 (7-12 tahun, n = 188), Kumpulan 2 (13 to 18 tahun, n = 196) and Kumpulan 3 (19 to 24 tahun, n = 200). Pengukuran dilakukan menggunakan topografer kornea (CTK 922 dari Haag Streit, Jerman), pakometer ultrasonik (Corneo-Gage Plus 2 dari Sonogage Incorporated) dan auto refraktometer (Auto-Ref R1 dari Canon, Jepun). Dimensi okular bangsa Melayu yang diukur didapati lebih kecil dari bangsa lain di seluruh dunia. Perbezaan yang signifikan juga didapati untuk semua pengukuran dengan peningkatan umur (p < 0.05). Keputusan kajian ini boleh dijadikan rujukan untuk nilai dimensi okular populasi Melayu muda Malaysia di masa hadapan.
In forensic entomology practice, it is more common to use raw animal tissue to breed dipteran larvae and it often brings unpleasant odour in the laboratory. Few studies suggested the use of synthetic diets, mainly agar-based media, as alternatives to animal tissue but it is rarely being practiced in forensic entomology laboratory. The present study observed the growth of a forensically important fly, Megaselia scalaris (Loew) on raw cow’s liver, nutrient agar, casein agar and cow’s liver agar. A total of 100 M. scalaris eggs were transferred each into the different media and placed in an incubator at 30°C in a continuous dark condition. Data on length and developmental period were collected by randomly sampling three of the largest larvae from each rearing media, twice a day at 0900 and 1500 hours until pupariation. M. scalaris larvae reared on raw cow’s liver recorded the highest mean length (4.23 ± 1.96 mm) followed by cow’s liver agar (3.79 ± 1.62 mm), casein agar (3.14 ± 1.16 mm) and nutrient agar (3.09 ± 1.11 mm). Larval length in raw liver and liver agar were significantly different from those in nutrient and casein agar (p < 0.05). Larvae bred in liver agar and raw liver recorded the shortest larval duration before entering the post-feeding stage (89 hours), followed by nutrient agar (119 hours) and casein agar (184 hours). Total developmental time from oviposition until adult emergence for M. scalaris in liver agar and raw liver was approximately 163 hours. All puparia in nutrient agar and casein agar failed to hatch. This research highlighted the potential use of cow’s liver agar as an alternative diet of raw liver to culture M. scalaris in laboratory.
Kajian kes ini dilakukan untuk mengenal pasti tahap kebersihan diri pengendali makanan dan kebersihan kafetaria di kolej kediaman Universiti Kebangsaan Malaysia (UKM). Seramai 75 responden telah terlibat. Data demografi menunjukkan terdapat responden yang tidak mendapat suntikan demam kepialu (32%) dan tidak mempuyai sijil kursus pengendali makanan (49.3%). Selain itu, lebih separuh bilangan responden adalah bukan warganegara (50.73%). Dapatan berkaitan amalan kebersihan diri menunjukkan 7 item mempunyai peratusan yang agak baik (70.3% – 87.5%) manakala 7 item yang lain mempunyai peratusan kurang baik (26.4% – 68%). Kajian juga menunjukkan terdapat 12 item berkaitan kebersihan kafetaria yang dipatuhi dan 9 item yang tidak dipatuhi daripada 21 item yang dinilai. Ujian statistik menunjukkan wujud perbezaan yang signifikan (U = 472, p = 0.01) antara pengendali makanan yang warganegara dan bukan warganegara di mana warganegara mempunyai amalan kebersihan diri yang lebih baik berbanding bukan warganegara. Dapatan kajian juga menunjukkan wujud hubungan yang positif dan signifikan di antara kebersihan diri dan kebersihan kafetaria (χ2 = 6.432, p = 0.011). Walau bagaimanapun, kekuatan hubungannya adalah sederhana (Φ = 0.29). Kesimpulannya, pengendali makanan yang warganegara mempunyai amalan kebersihan diri yang baik dan akan menjana suasana persekitaran kafetaria yang bersih.
Limited studies on prevalence and risk factors of Premature Coronary Artery Disease (PCAD) were done in Malaysia, primarily on lipid profile. This cross sectional study aims to identify any changing patterns in prevalence and risk factors of Premature CAD between 2000 and 2012. From 2000 to 2012 we included 21862 patients who underwent the first Percutaneous Coronary Intervention (PCI). Analysis of risk factors was done to 1660 and 2098 patients from year 2007 and 2012 respectively. Age of less than 45 years was taken as PCAD. Data was collected from PCI database of National Heart Institute (NHI), NHI TrakCare System, and patients’ medical records. PCAD significantly decreased from 18.8% (2000) to 11.6% (2012). Malay ethnicity showed increasing trend over the years from 55.1% to 66.9%. Multiple logistic regression analysis in 2007 showed that smoking had the higher risk (AOR=2.52), followed by male gender (AOR=2.06), family history of PCAD (AOR=1.96), Indian ethnicity, (AOR=1.65), triglycerides level (AOR=1.20) and BMI (AOR=1.06). In 2012, family history of PCAD had the highest risk (AOR=2.00) followed by smoking (AOR=1.91) and BMI (AOR=1.11). There are changes in risk factors patterns of premature CAD between 2007 and 2012. Most of them are preventable at earlier stage.
Cognitive Impairment is common in late life and may be due to the normal process of ageing, or associated with physical or mental disorder which contributes to a decrease in quality of life, neuropsychiatric symptoms, increased disability and increased healthcare cost. The aim of this study is to determine the prevalence of cognitive impairment among the elderly members in NACSCOM in Day Care Centres within the Klang Valley and its associated socio-demographic factors such as age, gender and educational level. This cross-sectional study was conducted on 101 members of NACSCOM in Day Care Centres of Damansara,Subang Jaya and Setapak using assisted questionnaires as the research tool. The questionnaire comprising of a total of 10 questions based on Elderly Cognitive Assessment Questionnaires (ECAQ), consisted of three parts, memory, orientation and recall. One correctly answered question earned the respondent one mark. The total score for ECAQ is 10 where respondents with scores of 5 and below were identified as having cognitive impairment. Data collected was analyzed using Chi-square test (SPSS version 18). The prevalence of cognitive impairment among the elderly members of NACSCOM in Day Care Centres within the Klang Valley was 4.0%. This study also showed that there was no statistically significant association between cognitive impairment and sociodemographic factors such as age, gender and education. Prevalence of cognitive impairment among the members of NACSCOM in Day Care Centres within the Klang Valley was found to be low. This could be attributed to the fact that members actively participated in activities organized by NACSCOM. The study also did not find any statistically significant association between cognitive impairment and age, gender and education.
A cross sectional survey was conducted in Kampung Datuk Kerarnat, an urbanized residential area in Kuala Lumpur from August to November ZOO5 to assess knowledge, attitude and preventive practices on dengue among its residents. A two stage sampling strategy was used to select survey household. An adult aged at least 21 years old was identified from each selected household and interviewed using a standardized questionnaire. Data was collected on demographics, dengue related KAP and house-types. Knowledge, attitude and practice were assessed using a scoring system. Each appropriate answer was given a point and the points for each section of the questionnaire were totalled. Knowledge was assessed as ‘good' or ‘moderate to poor’ based on arbitrary cut-off point. Out of 133 respondents interviewed, 78.2% were able to identify at least one clinical sign of dengue, 73% knew that dengue fever was caused by the bite of dengue infected Aedes mosquitoes, 71 % correctly identified breeding sites, 69.2% correctly identified the Aedes mosquito and 42% correctly reported biting times ofthe mosquito vector. Overall, knowledge
was categorized as poor, attitude was good and dengue control and prevention practices was moderately poor. There was a weak but significant positive correlation between knowledge and practice (r=0.271, p=0.002) but there was no significant correlation between attitude with practice and between attitude with knowledge (p>0.05) . The results suggested that inspite of good attitude l
on dengue fever, it did not correlate with good practices and good knowledge in dengue prevention. We conclude that there is a need to increase health promotion activities to increase knowledge which forms the basis for preventive practices as part of the strategy to control dengue. Preventive strategies are the only means of controlling the disease.
The objectives of this study were to determine the prevalence of HI V iryfection, risk factors and to measure the knowledge on AIDS among fishermen in Terengganu. In this survey fishermen registered with the Malaysian Fishery Development Board in Terengganu were studied. There were 600 eligible fishermen based on a list provided by the Malaysian Fishery Development Board (MFDB). Study sites were at 6 loading centres where health personnel awaited returning fishermen between 4. 00pm —7. 00 pm during a period of one month, A total of 542 registeredfshermen were studied and this corresponded to a response rate of 90.3 %. The majority of the fishermen were Malays (98.6%}, Nine fishermen were tested positive to HIV antibody and this corresponds to a
g prevalence of I. 7%. Prevalence of HIV is higher among those with a positive history of drug use, single marital status and also among the unskilled workers who represented the socio-economically poorer group of fishermen. Almost 89% of respondents have heard about HIV/AIDS and among these, 93% received information through TV and radio. The mean knowledge score was significantly higher among fishermen admitting to drug taking, sex with prostitutes, and those who have had at least a secondary school education. The Prevalence of HIV infection among fishermen is higher than in the general population. Risk characterisation of HI V injection was statistically signyicant onlv among fishermen who gave positive history of drug used. Findings also suggest that poorer fishermen based on multiple indicators to socioeconomic status had a higher risk of being HIV positive as well as being less knowledgeable about AIDS, Health promotion strategies should focus on the use of TV and radio as an interactive medium to reach out to risk groups among fishermen as its popularity has been determined by this study.