Displaying publications 121 - 140 of 168 in total

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  1. Fulltext Getting to know journal bibliographic databases
    Ng KH, Peh WC
    Singapore Med J, 2010 Oct;51(10):757-60; quiz 761.
    PMID: 21103809
    A bibliographic database is an organised digital collection of references to published literature. A bibliographic database may be general in scope or may cover a specific academic discipline. There are many types of medical and general bibliographic databases. They cover biomedical and scientific literature, morbidity and mortality statistics, therapeutic regimens, medical records, images and reviews of evidence-based medicine. Getting to know these databases will help researchers and authors to enhance their writing and publishing endeavours.
    Matched MeSH terms: Biomedical Research/methods
  2. Fulltext The Pan-Asian Resuscitation Outcomes Study (PAROS) clinical research network: what, where, why and how
    Doctor NE, Ahmad NS, Pek PP, Yap S, Ong ME
    Singapore Med J, 2017 07;58(7):456-458.
    PMID: 28741005 DOI: 10.11622/smedj.2017057
    Out-of-hospital cardiac arrest (OHCA) is a global health concern with an incidence rate of 50-60 per 100,000 person-years. To improve OHCA survival rates, several cardiac arrest registries have been set up in North America and Europe, such as the Resuscitation Outcomes Consortium, Cardiac Arrest Registry to Enhance Survival, Ontario Prehospital Advanced Life Support and European Registry of Cardiac Arrest. In Asia, however, there was previously no concerted effort in prehospital emergency care research owing to differences in prehospital emergency medical services systems, data collection methods and outcome reporting between countries. Recognising the need for a collaborative prehospital emergency care research group in Asia, researchers from seven countries in the Asia-Pacific region (including Japan, South Korea, Taiwan, Thailand, United Arab Emirates-Dubai, Singapore and Malaysia) established the Pan-Asian Resuscitation Outcomes Study (PAROS) clinical research network in 2010. This paper gives the overview, methodology and research accomplishments of the PAROS network.
    Matched MeSH terms: Biomedical Research/organization & administration
  3. A Review of Gastric Cancer Research in Malaysia
    Lim KG, Palayan K
    Asian Pac J Cancer Prev, 2019 Jan 25;20(1):5-11.
    PMID: 30677863
    Incidence rates of gastric cancer in Malaysia has declined by 48% among males and 31% among females in the latest reporting period of 13 years. Malays used to have age-standardized-rates only a fifth of those in Chinese and Indians, but the incidence among them is slightly rising even as the rates drop in the other races. Besides ethnicity, a low level of education, high intake of salted fish and vegetables, H pylori infection and smoking are risk factors. Consumption of fresh fruit and vegetable is protective. Variation in the strains of H pylori infection affect gastric cancer risk, with hspEAsia isolates among Chinese appearing linked to a high incidence than with hpAsia2 or hpEurope strains among Indians and Malays. It was reported in the 1980s that only about 3% of patients presented with early gastric cancer, but more encouraging rates reaching 27% with Stage 1 and 2 disease have been reported in the twenty-first century from leading centres. More tumours occur in the distal stomach except in Kelantan, where the incidence is low and main site is the cardia. Prompt endoscopy is advocated and open access, with direct referrals, to such services using a weighted scoring system should be more utilized. In view of the high rate of late disease laparoscopic staging unnecessary laparotomy needs to be avoided. Late presentation of gastric cancer however, is still predominant and the mortality to incidence ratio is relatively high. Besides seeking to reduce risk factors and achieve early detection, implementation of improved care for patients with late disease must be promoted in Malaysia.
    Matched MeSH terms: Biomedical Research*
  4. Fulltext Strengthening Noncommunicable Disease Research Capacity and Chronic Disease Outcomes in Low- and Middle-Income Countries in South Asia: Implementation and Evaluation of the ASCEND Program
    Byrnes A, Haregu TN, Pasricha N, Singh K, Thirunavukkarasu S, Wickkramasinghe K, et al.
    Asia Pac J Public Health, 2019 Sep;31(6):536-547.
    PMID: 31409121 DOI: 10.1177/1010539519867791
    This article describes the design, outcomes, challenges, and lessons learned from the ASian Collaboration for Excellence in Non-Communicable Disease (ASCEND) program, implemented between 2011 and 2015 in India, Sri Lanka, and Malaysia. The program involved a blended-delivery model, incorporating online and face-to-face training, mentoring, and supervision of trainees' research projects. Evaluation data were collected at baseline, 6, 12, 18, and 24 months. Intended outcomes, lessons, and challenges were summarized using a logic model. During the program period, 48 participants were trained over 2 cohorts in June 2011 and 2012. The trainees published 83 peer-reviewed articles between 2011 and 2015. Additionally, 154 presentations were given by trainees at national and international conferences. Underutilization of the online learning management system was an important challenge. Utilizing a combination of intensive face-to-face and online learning and mentoring of early career researchers in low- and middle-income countries has great potential to enhance the research capacity, performance, and outputs.
    Matched MeSH terms: Biomedical Research/organization & administration*
  5. Fulltext Review: an urgent need for research on factors impacting adherence to and retention in care among HIV-positive youth and adolescents from key populations
    Lall P, Lim SH, Khairuddin N, Kamarulzaman A
    J Int AIDS Soc, 2015;18(2 Suppl 1):19393.
    PMID: 25724503 DOI: 10.7448/IAS.18.2.19393
    The 50% increase in HIV-related deaths in youth and adolescents (aged 10-24) from 2005 to 2012 highlights the need to improve HIV treatment and care in this population, including treatment adherence and retention. Youth and adolescents from key populations or young key populations (YKP) in particular are highly stigmatized and may face additional barrier(s) in adhering to HIV treatment and services. We reviewed the current knowledge on treatment adherence and retention in HIV care among YKP to identify gaps in the literature and suggest future directions to improve HIV care for YKP.
    Matched MeSH terms: Biomedical Research
  6. Is there a role for academic medical centers in emerging markets?
    Wiener CM, Thompson SJ, Wu S, Chellappa M, Hasham S
    World Hosp Health Serv, 2012;48(4):4-6.
    PMID: 23484425
    Governments in emerging markets face mounting challenges in managing health spending, building capability and capacity, modernizing ageing infrastructure, and investing in skills and resources. One path to overcoming these challenges is to establish new public-private models of health care development and delivery based on United States academic medical centers, whose missions are to advance medical education and clinical delivery. Johns Hopkins Medicine is a participant in the collaboration developing between the Perdana University Hospital and the Perdana University Graduate School of Medicine in Malaysia. These two organizations comprise an academic health science center based on the United States model. The Perdana project provides constructive insights into the opportunities and challenges that governments, universities, and the private sector face when introducing new models of patient care that are integrated with medical education, clinical training, and biomedical research.
    Matched MeSH terms: Biomedical Research
  7. Fulltext The impact of a faculty development programme for health professions educators in sub-Saharan Africa: an archival study
    Frantz JM, Bezuidenhout J, Burch VC, Mthembu S, Rowe M, Tan C, et al.
    BMC Med Educ, 2015;15:28.
    PMID: 25879491 DOI: 10.1186/s12909-015-0320-7
    In 2008 the sub-Saharan FAIMER Regional Institute launched a faculty development programme aimed at enhancing the academic and research capacity of health professions educators working in sub-Saharan Africa. This two-year programme, a combination of residential and distance learning activities, focuses on developing the leadership, project management and programme evaluation skills of participants as well as teaching the key principles of health professions education-curriculum design, teaching and learning and assessment. Participants also gain first-hand research experience by designing and conducting an education innovation project in their home institutions. This study was conducted to determine the perceptions of participants regarding the personal and professional impact of the SAFRI programme.
    Matched MeSH terms: Biomedical Research/education*; Biomedical Research/methods; Biomedical Research/standards
  8. Socio-economic determinants of nutritional status of children in rural peninsular Malaysia
    Marjan ZM, Taib MN, Lin KG, Siong TE
    Asia Pac J Clin Nutr, 1998 Dec;7(3/4):307-10.
    PMID: 24393689
    The data presented is part of the findings from a four-year collaborative research project between Universiti Putra Malaysia, the Institute for Medical Research and the Ministry of Health Malaysia. The project assessed the nutritional status of the major functional groups in Peninsular Malaysia. Mukim Sayong and Pulau Kemiri in the District of Kuala Kangsar, Perak were two of the subdistricts selected to represent small rubber holdings in Peninsular Malaysia. This paper attempts to analyse the socio-economic profile of the households and the nutritional status of children below 9 years of age. A total of 307 households were studied. Approximately 63% of the households were involved in rubber activities and the majority of them were hired tappers. The average monthly income of the households was RM467 and the income ranged between RM30 to RM2120. Based on the per capita poverty line income of RM84.38, it was found that 14.1% of the households earned less than RM42.19, which can be considered as hard-core poor, while 32.7% were poor (monthly per capita income between RM42.19 and RM84.38). Slightly more than half (52.7%) earned income above the poverty line. The average family size was 4.5, ranging from 1 through to 16. The majority of the heads of households (56.6%) had between 3 and 6 years of education, and 14.5% did not receive any formal education. The prevalence of stunting among children 0-5 years of age was 26%, while 31.5% were underweight and 3.8% wasted. Among children aged between 5 and 9 years, almost the same pattern of nutritional status was noted. The overall percentages of stunting, underweight and wasting among these children were 29.2%, 26.1% and 0.62%, respectively. Analysis on nutritional status according to income level showed a noticeable difference in the prevalence of malnutrition in children above and below the poverty line income. The Student's t-test indicated significant differences in weight-for-age and weight-for-height between the two poverty line income for children below 5 years of age. Pearson's correlation coefficient showed a significant correlation between height-for-age with household size (r = -0.26, p<0.05), and monthly per capita income with weight-for-height (r = 0.25, p<0.05). There was a highly significant correlation between acreage of land cultivated and weight-for-height (r = 0.42, p<0.01), and weight-for-age (r = 0.25, p<0.05). The findings indicated the influence of socio-economic factors on the nutritional status of children.
    Matched MeSH terms: Biomedical Research
  9. Fulltext Mapping the Age of Laboratory Rabbit Strains to Human
    Sengupta P, Dutta S
    Int J Prev Med, 2020;11:194.
    PMID: 33815718 DOI: 10.4103/ijpvm.IJPVM_530_18
    Rabbit strains find immense application in biomedical research with every strain having their discrete advantage in specific research endeavor. Acceptability of rabbit strains as laboratory animals owes to their breeding ease, availability, cost-effectiveness, ethical conveniences, larger size, compared to rats and mice, and responsiveness. With respect to different life phases, the article displays that one human year is equivalent to: (1) in developmental phase, 56.77 days for New Zealand White (NZW) and New Zealand Red (NZR) rabbits, 71.01 days for Dutch belted and Polish rabbits, and 85.28 days for Californian rabbits; (2) in the prepubertal phase, 13.04 days for NZW and Dutch belted, 15.65 days for NZR and Californian, and 10.43 days for Polish rabbits; (3) in the adult phase, 18.25 days for NZW and Californian rabbits, 22.75 days for NZR, and 12 days for Dutch Belted and Polish rabbits; (4) during reproductive senescence, 42.94 days for NZW, NZR and Californian rabbits, 28.62 days for Dutch belted, and 25.05 days for Polish rabbits; (5) in the post-senescence phase, 50.34 days for NZW, 25.17 days for NZR, Dutch Belted and Californian and 31.46 days for Polish rabbits. The laboratory rabbit strains differ in various physiological, developmental and genetic make-ups, which also reflect upon the correlation of their age at different life stages with that of a human. The present article aids selection of laboratory rabbit strain of accurate age as per experimental need, by precisely relating the same with age of human considering different life stages.
    Matched MeSH terms: Biomedical Research
  10. Fulltext Intervention for Diabetes with Education, Advancement and Support (IDEAS) study: protocol for a cluster randomised controlled trial
    Lee JY, Chan CK, Chua SS, Ng CJ, Paraidathathu T, Lee KK, et al.
    BMC Health Serv Res, 2016 Sep 29;16(1):524.
    PMID: 27683021 DOI: 10.1186/s12913-016-1782-y
    BACKGROUND: The high market penetration of mobile phones has triggered an opportunity to combine mobile technology with health care to overcome challenges in today's health care setting. Although Malaysia has a high Internet and mobile penetration rate, evaluations of the efficacy of incorporating this technology in diabetes care is not common. We report the development of a telemonitoring coaching system, using the United Kingdom (UK) Medical Research Council (MRC) framework, for patients with type 2 diabetes mellitus.

    METHODS: The Intervention for Diabetes with Education, Technological Advancement and Support (IDEAS) study is a telemonitoring programme based on an empowerment philosophy to enable participants to be responsible for their own health decision and behaviour. An iterative cycle of development, piloting, and collating qualitative and quantitative data will be used to inform and refine the intervention. To increase compliance, the intervention will be designed to encourage self-management using simple, non-technical knowledge. The primary outcomes will be HbA1c, blood pressure, total cholesterol, and quality of life and diabetes self-efficacy. In addition, an economic analysis on health service utilisation will be collected.

    DISCUSSION: The mixed-method approach in this study will allow for a holistic overview of using telemonitoring in diabetes care. This design enables researchers to understand the effectiveness of telemonitoring as well as provide insights towards the receptiveness of incorporating information technology amongst type 2 diabetes patients in a community setting.

    TRIAL REGISTRATION: ClinicalTrials.gov NCT02466880 Registered 2 June 2015.
    Matched MeSH terms: Biomedical Research
  11. Fulltext Evaluation of two cell culture media in culturing rat full term amniotic fluid cells
    Ferdaos, N., Karuppiah, T., Rosli, R., Yazid, M. N., Nordin, N.
    Malaysian Journal of Medicine and Health Sciences, 2011;7(2):81-85.
    MyJurnal
    Introduction: Amniotic fluid (AF) consists of heterogenous population of cells with high diagnostic
    and therapeutic values. The study of rat amniotic fluid cells is very limited, despite the extensive use
    of this animal model in biomedical research. Primary culture of rat AF cells, especially from full term pregnancies has not been well established. Here we attempt to determine the suitable medium in
    culturing rat AF cells that would enhance the cell viability, growth rate and heterogeneity. Methods:
    The cell viability, growth rate and heterogeneity of rat AF cells were compared upon culturing the
    primary cells in two different media; Amniomax or RPMI. Cell viability study was carried out using
    trypan blue staining, while the growth rate was monitored based on the time required to passage the cells (population doubling time in hour). The heterogeneity of cells was examined based on the morphology of the cells. Statistical analysis was performed using t-test. Results: Amniomax was observed to provide a better culture condition in culturing rat AF cells as the cells are more viable, grow faster and more heterogenous as compared to the cells grown in RPMI. Conclusion: Amniomax is a more suitable medium for high quality and viability of full term rat AF cell culture, as compared to RPMI. Thus, warranting propagation of more rat AF cells for biomedical research.
    Matched MeSH terms: Biomedical Research
  12. Fulltext Impacts of gender bias
    Khalib, A.L., Suriyati, A.A.
    Malaysian Journal of Community Health, 2007;13(1):1-10.
    MyJurnal
    Gender bias are most obvious in the distribution of income and wealth. This reflects women’s unequal position in the labour market , their less favorable treatment in most social security systems and their lower status within the household. Discrimination against women is also evident in the political sphere. Their access to power is not commensurate with their numbers, their needs or their contributions as citizens. As well as affecting women’s physical and mental health, gender bias also affect the quality of the services they receive. In most developed countries, women are offered equal access to basic health care. However their use of those service may be hindered by a number of gender related factors which are likely to affect poor women in particular. In health organization, gender bias gives significant impact to the evaluation of staff performance, increase stress level and miscommunication. It is also influence the leadership style and also can create ‘glass ceiling’ phenomenon. Job dissatisfaction , absenteeism and high turn over are also the consequences of gender bias. Alongside the development of gender sensitive methods of routine data collection, gender bias in health research will also need to be addressed. Most biomedical research continues to be based on the unstated assumption that women and men are physiologically similar in all respects apart from their reproductive systems. Other biological differences are ignored, as are the social/gender differences that have such a major impact on health.
    Matched MeSH terms: Biomedical Research
  13. Fulltext Respiratory symptoms and pulmonary function among male steel workers in Terengganu, Malaysia
    Nurul, A.H., Shamsul Bahri, M.T., Noor Hassim, I.
    Malaysian Journal of Public Health Medicine, 2014;14(1):10-18.
    MyJurnal
    A cross sectional study was carried out to determine the relationship between dust exposure and pulmonary function in male steel workers in Terengganu, Malaysia. The investigation included spirometric testing and detailed personal interviews using a structured questionnaire adopted from British Medical Research Council (BRMC) Questionnaire on respiratory symptoms. Respiratory symptoms commonly reported by the male workers were morning phlegm (33.1%), shortness of breath (31.9%), chest tightness (30.4%), and morning cough (17.8%). Age and duration of employment were among the factors associated with respiratory symptoms (p
    Matched MeSH terms: Biomedical Research
  14. Fulltext Influenza surveillance in Malaysia: 1997 - 2001
    Nor Shahidah, Ismail Merican, Raman Ismail
    Malaysian Journal of Public Health Medicine, 2003;3(1):11-15.
    MyJurnal
    Influenza has always been wrongly perceived as a minor disease which is no dwerent than common cold. Influenza affecting all age groups cause a considerable morbidity and mortality although the data are not well established in Asia Pacwc. In the United States, it claims similar order of mortality as that due to car accidents. Inflluenza A and B can cause epidemic human disease. New Influenza virus variants develop frequently due to antigenic dry?. The rapid evolution of both influenza A and B virus is responsible for annual influenza epidemics in humans. Although in Malaysia, Influenza Surveillance began in 1954, the disease awareness is still low. It is
    prudent to continue the surveillance throughout in order to monitor the seasonal trend, circulating strain as well to prepare us from an epidemic or pandemic. Institute for Medical Research, being the sole WHO National Reference lab in this country committed in improving the Influenza Surveillance which will involve all the states in Malaysia in the near future.
    Matched MeSH terms: Biomedical Research
  15. Fulltext Computerized Morphometric Analysis of Eryptosis
    Jacob SS, Prasad K, Rao P, Kamath A, Hegde RB, Baby PM, et al.
    Front Physiol, 2019;10:1230.
    PMID: 31649550 DOI: 10.3389/fphys.2019.01230
    Eryptosis is the suicidal destruction-process of erythrocytes, much like apoptosis of nucleated cells, in the course of which the stressed red cell undergoes cell-shrinkage, vesiculation and externalization of membrane phosphatidylserine. Currently, there exist numerous methods to detect eryptosis, both morphometrically and biochemically. This study aimed to design a simple but sensitive, automated computerized approach to instantaneously detect eryptotic red cells and quantify their hallmark morphological characteristics. Red cells from 17 healthy volunteers were exposed to normal Ringer and hyperosmotic stress with sodium chloride, following which morphometric comparisons were conducted from their photomicrographs. The proposed method was found to significantly detect and differentiate normal and eryptotic red cells, based on variations in their structural markers. The receiver operating characteristic curve analysis for each of the markers showed a significant discriminatory accuracy with high sensitivity, specificity and area under the curve values. The software-based technique was then validated with RBCs in malaria. This model, quantifies eryptosis morphometrically in real-time, with minimal manual intervention, providing a new window to explore eryptosis triggered by different stressors and diseases and can find wide application in laboratories of hematology, blood banks and medical research.
    Matched MeSH terms: Biomedical Research
  16. Body plethysmography for measuring airway resistance in patients with bilateral vocal fold immobility
    Sairin ME, Mat Baki M, Manap RA, Puteh SEW, Azman M, Mohamed AS
    Auris Nasus Larynx, 2020 Oct;47(5):842-848.
    PMID: 32273190 DOI: 10.1016/j.anl.2020.03.004
    OBJECTIVE: This study investigated the reliability of body plethysmography in comparison to spirometry in objectively measuring upper airway functions.

    METHODS: The study population consisted of 53 participants, 23 patients with BVFI after endolaryngeal laser posterior cordectomy and 30 healthy volunteers. All of them had body plethysmography (airway resistance, Raw), spirometry (ratio of forced expiratory flow at 50% to forced inspiratory flow at 50%, FEF50/FIF50 and peak inspiratory flow, PIF), 6 min-walking-test (6MWT) and Medical Research Council (MRC) dyspnea scale measurements. The tests were repeated and reliability was evaluated using intraclass correlation (ICC) and Spearman correlation.

    RESULTS: The reliability of Raw was high with ICC of 0.92, comparable to the spirometry measurements: FEF50/FIF50(ICC = 0.72) and PIF (ICC = 0.97). The mean of Raw was significantly higher in patient group. A strong significant correlation between Raw and MRC dyspnea scale (r = 0.79; p<0.05) and a moderate negative correlation between Raw and 6MWT (r = 0.4; p<0.05) was demonstrated.

    CONCLUSION: Body plethysmography (Raw) is a reliable tool in objective measurement of upper airway resistance that reflects the patient's perception of breathlessness. A larger number of participants are necessary to confirm this finding.

    Matched MeSH terms: Biomedical Research
  17. Fulltext Discovery of novel genic-SSR markers from transcriptome dataset of an important non-human primate, Macaca fascicularis
    Chang W, Ee-Uli J, Ng WL, Rovie-Ryan JJ, Tan SG, Yong CSY
    Sci Rep, 2019 06 11;9(1):8504.
    PMID: 31186469 DOI: 10.1038/s41598-019-44870-4
    Macaca fascicularis, also known as the cynomolgus macaque, is an important non-human primate animal model used in biomedical research. It is an Old-World primate widely distributed in Southeast Asia and is one of the most abundant macaque species in Malaysia. However, the genetic structure of wild cynomolgus macaque populations in Malaysia has not been thoroughly elucidated. In this study, we developed genic-simple sequence repeat (genic-SSR) markers from an in-house transcriptome dataset generated from the Malaysian cynomolgus macaque via RNA sequencing, and applied these markers on 26 cynomolgus macaque individuals. A collection of 14,751 genic-SSRs were identified, where 13,709 were perfect SSRs. Dinucleotide repeats were the most common repeat motifs with a frequency of 65.05%, followed by trinucleotide repeats (20.55%). Subsequently, we designed 300 pairs of primers based on perfect di- and trinucleotide SSRs, in which 105 SSRs were associated with functional genes. A subset of 30 SSR markers were randomly selected and validated, yielding 19 polymorphic markers with an average polymorphism information content value of 0.431. The development of genic-SSR markers in this study is indeed timely to provide useful markers for functional and population genetic studies of the cynomolgus macaque and other related non-human primate species.
    Matched MeSH terms: Biomedical Research
  18. Fulltext The Effect of Repetitive Transcranial Magnetic Stimulation on Postural Stability After Acute Stroke: A Clinical Trial
    Forogh B, Ahadi T, Nazari M, Sajadi S, Abdul Latif L, Akhavan Hejazi SM, et al.
    Basic Clin Neurosci, 2017 Sep-Oct;8(5):405-411.
    PMID: 29167727 DOI: 10.18869/nirp.bcn.8.5.405
    Introduction: Balance impairment is a common problem and a major cause of motor disability after stroke. Therefore, this study aimed to investigate whether low-frequency repetitive Transcranial Magnetic Stimulation (rTMS) improves the postural balance problems in stroke patients.

    Methods: This randomized double blind clinical trial with 12 weeks follow-up was conducted on stroke patients. Treatment was carried with 1 Hz rTMS in contralateral brain hemisphere over the primary motor area for 20 minutes (1200 pulses) for 5 consecutive days. Static postural stability, Medical Research Council (MRC), Berg Balance Scale (BBS), and Fugl-Meyer assessments were evaluated immediately, 3 weeks and 12 weeks after intervention.

    Results: A total of 26 patients were enrolled (age range=53 to 79 years; 61.5% were male) in this study. Administering rTMS produced a significant recovery based on BBS (df=86, 7; F=7.4; P=0.01), Fugl-Meyer Scale (df=86, 7; F=8.7; P<0.001), MRC score (df=87, 7; F=2.9; P=0.01), and static postural stability (df=87, 7; F=9.8; P<0.001) during the 12 weeks follow-up.

    Conclusion: According to the findings, rTMS as an adjuvant therapy may improve the static postural stability, falling risk, coordination, motor recovery, and muscle strength in patients with stroke.
    Matched MeSH terms: Biomedical Research
  19. Fulltext The Nigerian Bioinformatics and Genomics Network (NBGN): a collaborative platform to advance bioinformatics and genomics in Nigeria
    Fatumo S, Ebenezer TE, Ekenna C, Isewon I, Ahmad U, Adetunji C, et al.
    Glob Health Epidemiol Genom, 2020;5:e3.
    PMID: 32742665 DOI: 10.1017/gheg.2020.3
    Africa plays a central importance role in the human origins, and disease susceptibility, agriculture and biodiversity conservation. Nigeria as the most populous and most diverse country in Africa, owing to its 250 ethnic groups and over 500 different native languages is imperative to any global genomic initiative. The newly inaugurated Nigerian Bioinformatics and Genomics Network (NBGN) becomes necessary to facilitate research collaborative activities and foster opportunities for skills' development amongst Nigerian bioinformatics and genomics investigators. NBGN aims to advance and sustain the fields of genomics and bioinformatics in Nigeria by serving as a vehicle to foster collaboration, provision of new opportunities for interactions between various interdisciplinary subfields of genomics, computational biology and bioinformatics as this will provide opportunities for early career researchers. To provide the foundation for sustainable collaborations, the network organises conferences, workshops, trainings and create opportunities for collaborative research studies and internships, recognise excellence, openly share information and create opportunities for more Nigerians to develop the necessary skills to exceed in genomics and bioinformatics. NBGN currently has attracted more than 650 members around the world. Research collaborations between Nigeria, Africa and the West will grow and all stakeholders, including funding partners, African scientists, researchers across the globe, physicians and patients will be the eventual winners. The exponential membership growth and diversity of research interests of NBGN just within weeks of its establishment and the unanticipated attendance of its activities suggest the significant importance of the network to bioinformatics and genomics research in Nigeria.
    Matched MeSH terms: Biomedical Research
  20. Malaysian Twin Registry
    Jahanfar S, Jaffar SH
    Twin Res Hum Genet, 2013 Feb;16(1):246-7.
    PMID: 23110917 DOI: 10.1017/thg.2012.80
    The National Malaysian Twin Registry was established in Royal College of Medicine, Perak, University Kuala Lumpur (UniKL) in June 2008 through a grant provided by UniKL. The general objective is to facilitate scientific research involving participation of twins and their family members in order to answer questions of health and wellbeing relevant to Malaysians. Recruitment is done via mass media, poster, and pamphlets. We now have 266 adult and 204 children twins registered. Several research projects including reproductive health study of twins and the role of co-bedding on growth and development of children are carried out. Registry holds annual activities for twins and seeks to provide health-related information for twins. We seek international collaboration.
    Matched MeSH terms: Biomedical Research*
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