Displaying publications 121 - 140 of 378 in total

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  1. Foo KY, Hameed BH
    Adv Colloid Interface Sci, 2010 Sep 15;159(2):130-43.
    PMID: 20673570 DOI: 10.1016/j.cis.2010.06.002
    Water scarcity and pollution rank equal to climate change as the most urgent environmental turmoil for the 21st century. To date, the percolation of textile effluents into the waterways and aquifer systems, remain an intricate conundrum abroad the nations. With the renaissance of activated carbon, there has been a steadily growing interest in the research field. Recently, the adoption of titanium dioxide, a prestigious advanced photo-catalyst which formulates the new growing branch of activated carbon composites for enhancement of adsorption rate and discoloration capacity, has attracted stern consideration and supports worldwide. Confirming the assertion, this paper presents a state of art review of titanium dioxide/activated carbon composites technology, its fundamental background studies, and environmental implications. Moreover, its major challenges together with the future expectation are summarized and discussed. Conclusively, the expanding of activated carbons composites material represents a potentially viable and powerful tool, leading to the plausible improvement of environmental conservation.
    Matched MeSH terms: Surface Properties
  2. Foo ME, Gopinath SCB
    Biomed Pharmacother, 2017 Oct;94:354-361.
    PMID: 28772213 DOI: 10.1016/j.biopha.2017.07.122
    Nanotechnology is the developing field, bringing the materials in the nanoscale level, has been applied in the interdisciplinary sciences. Different nanomaterials, such as gold, silver, zinc, copper and graphene are shown to have a wide range of applications. Among these, graphene is one of the faster upcoming two-dimensional nanomaterials utilized in various fields due to its positive features including the properties of thermal, electrical, strength and elasticity. Biomedical applications of graphene have been widely attested to be popular among academician and industrial partners for creating next generation medical systems and therapies. In this review, we selectively revealed the current applications of graphene in the interdisciplinary medical sciences.
    Matched MeSH terms: Surface Properties
  3. Foo ML, Tan CR, Lim PD, Ooi CW, Tan KW, Chew IML
    Int J Biol Macromol, 2019 Oct 01;138:1064-1071.
    PMID: 31301392 DOI: 10.1016/j.ijbiomac.2019.07.035
    Rod-shape particles have been a good drug carrier due to the long circulatory time, tumor accumulation and high cellular uptake in body. Acid-hydrolysed nanocrystalline cellulose (NCC) from empty fruit bunch exhibited a width of 13-30nm and a length of 150-360nm in rod-shape structure. NCC holds good potential as a bio-based drug carrier owing to its biodegradability and biocompatibility. Fourier-transform infrared spectroscopy results confirmed the binding of curcumin onto the NCC modified with tannic acid (TA) and decylamine (DA). TA-DA modification rendered NCC with a higher level of hydrophobicity, as evidenced by a substantial increase in contact angle from 45° to 73°. The modified NCC had the curcumin-binding efficiency in the range of 95-99%, which is at least twofold higher than the unmodified NCC at any curcumin concentration tested. This remarkable curcumin-binding effciency was comparable to that of commercialized NCC from wood-based origin. This work suggests NCC as a superior and sustainable drug carrier, while TA-DA modification is a promising approach to alter the surface property of NCC for an efficient binding of curcumin.
    Matched MeSH terms: Surface Properties
  4. Gan S, Piao SH, Choi HJ, Zakaria S, Chia CH
    Carbohydr Polym, 2016 Feb 10;137:693-700.
    PMID: 26686181 DOI: 10.1016/j.carbpol.2015.11.035
    Cellulose carbamate (CC) was produced from kenaf core pulp (KCP) via a microwave reactor-assisted method. The formation of CC was confirmed by Fourier transform infrared spectroscopy and nitrogen content analysis. The degree of substitution, zeta potential and size distribution of CC were also determined. The CC was characterized with scanning electron microscopy, X-ray diffraction and thermogravimetry analysis. The CC particles were then dispersed in silicone oil to prepare CC-based anhydrous electric stimuli-responsive electrorheological (ER) fluids. Rhelogical measurement was carried out using rotational rheometer with a high voltage generator in both steady and oscillatory shear modes to examine the effect of electric field strength on the ER characteristics. The results showed that the increase in electric field strength has enhanced the ER properties of CC-based ER fluid due to the chain formation induced by electric polarization among the particles.
    Matched MeSH terms: Surface Properties
  5. Ganguly A, Ian CK, Sheshala R, Sahu PS, Al-Waeli H, Meka VS
    J Mater Sci Mater Med, 2017 Mar;28(3):39.
    PMID: 28144851 DOI: 10.1007/s10856-017-5852-4
    The objective of this study was to prepare periodontal gels using natural polymers such as badam gum, karaya gum and chitosan. These gels were tested for their physical and biochemical properties and assessed for their antibacterial activity against Aggregatibacter actinomycetemcomitans and Streptococcus mutans, two pathogens associated with periodontal disease. Badam gum, karaya gum and chitosan were used to prepare gels of varying concentrations. Moxifloxacin hydrochloride, a known antimicrobial drug was choosen in the present study and it was added to the above gels. The gels were then run through a battery of tests in order to determine their physical properties such as pH and viscosity. Diffusion studies were carried out on the gels containing the drug. Antimicrobial testing of the gels against various bacteria was then carried out to determine the effectiveness of the gels against these pathogens. The results showed that natural polymers can be used to produce gels. These gels do not have inherent antimicrobial properties against A. actinomycetemcomitans and S. mutans. However, they can be used as a transport vehicle to carry and release antimicrobial drugs.
    Matched MeSH terms: Surface Properties
  6. Ganjali Dashti M, Abdeshahian P, Sudesh K, Phua KK
    Biofouling, 2016;32(4):477-87.
    PMID: 26963754 DOI: 10.1080/08927014.2015.1135328
    The objective of this study was to develop an optimized assay for Salmonella Typhi biofilm that mimics the environment of the gallbladder as an experimental model for chronic typhoid fever. Multi-factorial assays are difficult to optimize using traditional one-factor-at-a-time optimization methods. Response surface methodology (RSM) was used to optimize six key variables involved in S. Typhi biofilm formation on cholesterol-coated polypropylene 96-well microtiter plates. The results showed that bile (1.22%), glucose (2%), cholesterol (0.05%) and potassium chloride (0.25%) were critical factors affecting the amount of biofilm produced, but agitation (275 rpm) and sodium chloride (0.5%) had antagonistic effects on each other. Under these optimum conditions the maximum OD reading for biofilm formation was 3.4 (λ600 nm), and the coefficients of variation for intra-plate and inter-plate assays were 3% (n = 20) and 5% (n = 8), respectively. These results showed that RSM is an effective approach for biofilm assay optimization.
    Matched MeSH terms: Surface Properties
  7. Ge Y, Lakshmipriya T, Gopinath SC, Anbu P, Chen Y, Hariri F, et al.
    Int J Nanomedicine, 2019;14:7851-7860.
    PMID: 31632005 DOI: 10.2147/IJN.S222238
    BACKGROUND: Gestational diabetes mellitus is a commonly occurring metabolic disorder during pregnancy, affecting >4% of pregnant women. It is generally defined as the intolerance of glucose with the onset or initial diagnosis during pregnancy. This illness affects the placenta and poses a threat to the baby as it affects the supply of proper oxygen and nutrients.

    PURPOSE: Due to the high percentage of affected pregnant women, it should be mandatory to evaluate glucose levels during pregnancy and there is a need for a continuous monitoring system.

    METHODS: Herein, the investigators modified the interdigitated (di)electrodes (IDE) sensing surface to detect the glucose on covalently immobilized glucose oxidase (GOx) with the graphene. The characterization of graphene and gold nanoparticle (GNP) was performed by high-resolution microscopy.

    RESULTS: Sensitivity was found to be 0.06 mg/mL and to enhance the detection, GOx was complexed with GNP. GNP-GOx was improved the sensitive detection twofold from 0.06 to 0.03 mg/mL, and it also displayed higher levels of current changes at all the concentrations of glucose that were tested. High-performance of the above IDE sensing system was attested by the specificity, reproducibility and higher sensitivity detections. Further, the linear regression analysis indicated the limit of detection to be between 0.02 and 0.03 mg/mL.

    CONCLUSION: This study demonstrated the potential strategy with nanocomposite for diagnosing gestational diabetes mellitus.

    Matched MeSH terms: Surface Properties
  8. Gong QQ, Tay JYS, Veronica N, Xu J, Heng PWS, Zhang YP, et al.
    Pharm Dev Technol, 2023 Feb;28(2):164-175.
    PMID: 36683577 DOI: 10.1080/10837450.2023.2171434
    Surface roughness of carrier particles can impact dry powder inhaler (DPI) performance. There are opposing views on the effect of roughness on DPI performance. Hence, a systematic approach is needed to modify carrier surfaces and evaluate the impact on drug delivery. Carrier particle surfaces were modified by fluid bed coating with saturated lactose containing micronized lactose of different sizes (2, 5 and 8 μm) and coated to different levels (20, 40, 60 and 80%). Their drug delivery performance was assessed by the fine particle fraction (FPF). Roughness parameters, mean arithmetic roughness (Ra) and arithmetic mean height (Sa), of the carrier particles, were also evaluated using optical profilometry and scanning laser microscopy. Generally, particles of higher Ra had higher FPF. Higher Sa resulted in higher FPF only for particles with 60 and 80% coat levels. Reduced contact surface area between the drug particle and rougher carrier particle resulted in easier drug detachment during aerosolization. The 5 µm micronized lactose produced optimal carrier particles with respect to FPF and surface roughness. The study highlighted that with the ideal particles for surface roughening and coating level, surface roughening could be efficiently achieved by fluid bed coating for superior DPI performance.
    Matched MeSH terms: Surface Properties
  9. Gopinath SCB, Xuan S
    Biotechnol Appl Biochem, 2021 Jun;68(3):554-559.
    PMID: 32460382 DOI: 10.1002/bab.1961
    One of the current issues with thyroid tumor is early diagnosis as it makes the higher possibility of curing. This research was focused to detect and quantify the level of specific target sequence complementation of miR-222 with capture DNA sequence on interdigitated electrode (IDE) sensor. The aluminum electrode with the gap and finger sizes of 10 µm was fabricated on silicon wafer, further the surface was amine-functionalized for accommodating carboxylated-DNA probe. With DNA-target RNA complementation, the detection limit was attained to be 1 fM as estimated by a linear regression analysis [y = 1.5325x - 2.1171 R² = 0.9065] and the sensitivity was at the similar level. Current responses were higher by increasing the target RNA sequence concentrations. Control experiments with mismatched/noncomplementary sequences were failed to complement the capture DNA sequence immobilized on IDE, indicating the specific target validation. This research helps diagnosing and identifying the progression with thyroid tumor and miRNA being a potential "marker" in atypia diagnosis.
    Matched MeSH terms: Surface Properties
  10. Guo S, Li Y, Li R, Zhang P, Wang Y, Gopinath SCB, et al.
    Biotechnol Appl Biochem, 2020 May;67(3):383-388.
    PMID: 31876964 DOI: 10.1002/bab.1877
    Abdominal aortic aneurysm (AAA) is a serious, life-threatening vascular disease that presents as an enlarged area of the aorta, which is the main artery that carries blood away from the heart. AAA may occur at any location in the aorta, but it is mainly found in the abdominal region. A ruptured AAA causes serious health issues, including death. Traditional imaging techniques, such as computed tomography angiogram, magnetic resonance imaging, and ultrasound sonography, have been used to identify AAAs. Circulating biomarkers have recently become attractive for diagnosing AAAs due to their cost-effectiveness compared to imaging. Insulin-like growth factor 1 (IGF-1), a secreted hormone vital for human atherosclerotic plaque stability, has been found to be an efficient biomarker for AAA identification. In this report, immunosensing was performed by using an InterDigitated electrode (IDE) sensor to detect circulating levels of IGF-1. The detection limit of IGF-1 was found to be 100 fM with this sensor. Moreover, related protein controls (IGF-2 and IGFBP3) were not detected with the same antibody, indicating selective IGF-1 detection. Thus, immunosensing by using an IDE sensor may help to effectively diagnose AAAs and represents a basic platform for further development.
    Matched MeSH terms: Surface Properties
  11. Gupta S, Parolia A, Jain A, Kundabala M, Mohan M, de Moraes Porto IC
    J Indian Soc Pedod Prev Dent, 2015 Jul-Sep;33(3):245-9.
    PMID: 26156281 DOI: 10.4103/0970-4388.160402
    The aim of this in vitro study was an attempt to investigate the effect of different surface treatments on the bond strength between pre-existing composite and repair composite resin.
    Matched MeSH terms: Surface Properties
  12. Haafiz MK, Hassan A, Zakaria Z, Inuwa IM
    Carbohydr Polym, 2014 Mar 15;103:119-25.
    PMID: 24528708 DOI: 10.1016/j.carbpol.2013.11.055
    The objective of this study is to compare the effect of two different isolation techniques on the physico-chemical and thermal properties of cellulose nanowhiskers (CNW) from oil palm biomass obtained microcrystalline cellulose (MCC). Fourier transform infrared analysis showed that there are no significant changes in the peak positions, suggesting that the treatments did not affect the chemical structure of the cellulose fragment. Scanning electron microscopy showed that the aggregated structure of MCC is broken down after treatment. Transmission electron microscopy revealed that the produced CNW displayed a nanoscale structure. X-ray diffraction analysis indicated that chemical swelling improves the crystallinity of MCC while maintaining the cellulose I structure. Acid hydrolysis however reduced the crystallinity of MCC and displayed the coexistence of cellulose I and II allomorphs. The produced CNW is shown to have a good thermal stability and hence is suitable for a range of applications such as green biodegradable nanocomposites reinforced with CNW.
    Matched MeSH terms: Surface Properties
  13. Hameed BH, Tan IA, Ahmad AL
    J Hazard Mater, 2008 Oct 30;158(2-3):324-32.
    PMID: 18329169 DOI: 10.1016/j.jhazmat.2008.01.088
    Oil palm fibre was used to prepare activated carbon using physiochemical activation method which consisted of potassium hydroxide (KOH) treatment and carbon dioxide (CO(2)) gasification. The effects of three preparation variables: the activation temperature, activation time and chemical impregnation (KOH:char) ratio on methylene blue (MB) uptake from aqueous solutions and activated carbon yield were investigated. Based on the central composite design (CCD), a quadratic model and a two factor interaction (2FI) model were respectively developed to correlate the preparation variables to the MB uptake and carbon yield. From the analysis of variance (ANOVA), the significant factors on each experimental design response were identified. The optimum activated carbon prepared from oil palm fibre was obtained by using activation temperature of 862 degrees C, activation time of 1h and chemical impregnation ratio of 3.1. The optimum activated carbon showed MB uptake of 203.83 mg/g and activated carbon yield of 16.50%. The equilibrium data for adsorption of MB on the optimum activated carbon were well represented by the Langmuir isotherm, giving maximum monolayer adsorption capacity as high as 400mg/g at 30 degrees C.
    Matched MeSH terms: Surface Properties
  14. Hammadi NI, Abba Y, Hezmee MNM, Razak ISA, Jaji AZ, Isa T, et al.
    Pharm Res, 2017 06;34(6):1193-1203.
    PMID: 28382563 DOI: 10.1007/s11095-017-2135-1
    PURPOSE: Here, we explored the formulation of a calcium carbonate nanoparticle delivery system aimed at enhancing docetaxel (DTX) release in breast cancer.

    METHODS: The designed nano- anticancer formulation was characterized thorough X-ray diffraction (XRD), Fourier transformed infrared (FTIR), transmission electron microscopy (TEM) and field emission scanning electron microscopy (FESEM) and Brunauer-Emmett-Teller (BET) methods. The nano- anticancer formulation (DTX- CaCO3NP) was evaluated for drug delivery properties thorough in vitro release study in human body simulated solution at pH 7.4 and intracellular lysosomal pH 4.8.

    RESULTS: Characterization revealed the successful synthesis of DTX- CaCO3NP, which had a sustained release at pH 7.4. TEM showed uniformly distributed pleomorphic shaped pure aragonite particles. The highest entrapment efficiency (96%) and loading content (11.5%) were obtained at docetaxel to nanoparticles ratio of 1:4. The XRD patterns revealed strong crystallizations in all the nanoparticles formulation, while FTIR showed chemical interactions between the drug and nanoparticles with negligible positional shift in the peaks before and after DTX loading. BET analysis showed similar isotherms before and after DTX loading. The designed DTX- CaCO3NP had lower (p  0.05) effects at 48 h and 72 h. However, the DTX- CaCO3NP released less than 80% of bond DTX at 48 and 72 h but showed comparable effects with free DTX.

    CONCLUSIONS: The results showed that the developed DTX- CaCO3NP released DTX slower at pH 7.4 and had comparable cytotoxicity with free DTX at 48 and 72 h in MCF-7 cells.

    Matched MeSH terms: Surface Properties
  15. Hanafi Ismail, Rohani Abdul Majid, Razaina Mat Taib
    MyJurnal
    Linear density polyethylene (LDPE)/thermoplastic sago starch (TPSS), blended with and without the addition of compatibilizer [Polyethylene-grafted-Maleic Anhydride, (PE-g-MA)] were prepared for soil burial test. The test was conducted in the natural soil environment for 3 and 6 months. Different loading of TPSS (10, 20, 30, 40, and 50 wt. %) were used in this study. After soil burial, the blends were evaluated for their tensile properties and scanning electron microscopy (SEM) to observe the surface morphology properties after the test. For LDPE/TPSS, it was observed that the tensile strength decreased with the increase of soil burial time, as well as Young modulus and elongation at break (EB). The LDPE/TPSS/PE-g-MA also showed the same trend for the tensile properties, but with higher properties as compared to uncompatibilized blends. The tensile properties also decreased with the increase in the TPSS loading for both the LDPE/TPSS and LDPE/TPSS/PE-g-MA. Meanwhile,
    the scanning electron microscopy (SEM) on the blend surfaces after the soil burial test showed that degradability increased with the increase in the exposure time as well as the TPSS loading.
    Matched MeSH terms: Surface Properties
  16. Hasan S, Al Ali H, Al-Qubaisi M, Zobir Hussein M, Ismail M, Zainal Z, et al.
    Int J Nanomedicine, 2012;7:3351-63.
    PMID: 22848164 DOI: 10.2147/IJN.S30809
    A controlled-release formulation of an antihistamine, cetirizine, was synthesized using zinc-layered hydroxide as the host and cetirizine as the guest. The resulting well-ordered nanolayered structure, a cetirizine nanocomposite "CETN," had a basal spacing of 33.9 Å, averaged from six harmonics observed from X-ray diffraction. The guest, cetirizine, was arranged in a horizontal bilayer between the zinc-layered hydroxide (ZLH) inorganic interlayers. Fourier transform infrared spectroscopy studies indicated that the intercalation takes place without major change in the structure of the guest and that the thermal stability of the guest in the nanocomposites is markedly enhanced. The loading of the guest in the nanocomposites was estimated to be about 49.4% (w/w). The release study showed that about 96% of the guest could be released in 80 hours by phosphate buffer solution at pH 7.4 compared with about 97% in 73 hours at pH 4.8. It was found that release was governed by pseudo-second order kinetics. Release of histamine from rat basophilic leukemia cells was found to be more sensitive to the intercalated cetirizine in the CETN compared with its free counterpart, with inhibition of 56% and 29%, respectively, at 62.5 ng/mL. The cytotoxicity assay toward Chang liver cells line show the IC₅₀ for CETN and ZLH are 617 and 670 μg/mL, respectively.
    Matched MeSH terms: Surface Properties
  17. Hassan MH
    Med J Malaysia, 2004 May;59 Suppl B:164-5.
    PMID: 15468869
    There has been, and is still, concern about the high elastic modulus of Ti alloys compared to bone. Any reduction in the Young's modulus value of the implant is expected to enhance stress redistribution to the adjacent bone tissues, minimize stress shielding and eventually prolong device lifetime. Dynamic Monte Carlo simulation is used to predict the gradual reduction in Young's modulus values between the bulk of Ti alloys and the modified surface layers due to Ca ion implantation. The simulation can be used as a screening step when applying new alloys and/or coatings.
    Matched MeSH terms: Surface Properties
  18. Heboyan A, Vardanyan A, Karobari MI, Marya A, Avagyan T, Tebyaniyan H, et al.
    Molecules, 2023 Feb 08;28(4).
    PMID: 36838607 DOI: 10.3390/molecules28041619
    The cementation of indirect restoration is one of the most important steps in prosthetic and restorative dentistry. Cementation aims to bond the prosthetic restoration to the prepared enamel or enamel and dentine. Successful cementation protocols prevent biofilm formation at the margin between tooth and restoration and minimize mechanical and biological complications. With the advancements in dental cements, they have been modified to be versatile in terms of handling, curing, and bond strengths. This review presents updates on dental cements, focusing on the composition, properties, advantages, limitations, and indications of the various cements available. Currently, dental restorations are made from various biomaterials, and depending on each clinical case, an appropriate luting material will be selected. There is no luting material that can be universally used. Therefore, it is important to distinguish the physical, mechanical, and biological properties of luting materials in order to identify the best options for each case. Nowadays, the most commonly used dental cements are glass-ionomer and resin cement. The type, shade, thickness of resin cement and the shade of the ceramic, all together, have a tangible influence on the final restoration color. Surface treatments of the restoration increase the microtensile bond strength. Hence, the proper surface treatment protocol of both the substrate and restoration surfaces is needed before cementation. Additionally, the manufacturer's instructions for the thin cement-layer thickness are important for the long-term success of the restoration.
    Matched MeSH terms: Surface Properties
  19. Herawan SG, Ahmad MA, Putra A, Yusof AA
    ScientificWorldJournal, 2013;2013:545948.
    PMID: 24027443 DOI: 10.1155/2013/545948
    Activated carbons are regularly used the treatment of dye wastewater. They can be produced from various organics materials having high level of carbon content. In this study, a novel Pinang frond activated carbon (PFAC) was produced at various CO₂ flow rates in the range of 150-600 mL/min at activation temperature of 800°C for 3 hours. The optimum PFAC sample is found on CO₂ flow rate of 300 mL/min which gives the highest BET surface area and pore volume of 958 m²/g and 0.5469 mL/g, respectively. This sample shows well-developed pore structure with high fixed carbon content of 79.74%. The removal of methylene blue (MB) by 95.8% for initial MB concentration of 50 mg/L and 72.6% for 500 mg/L is achieved via this sample. The PFAC is thus identified to be a suitable adsorbent for removing MB from aqueous solution.
    Matched MeSH terms: Surface Properties
  20. Hisham S, Kadirgama K, Mohammed HA, Kumar A, Ramasamy D, Samykano M, et al.
    Molecules, 2020 Jun 28;25(13).
    PMID: 32605301 DOI: 10.3390/molecules25132975
    Friction and wear are the main factors in the failure of the piston in automobile engines. The objective of this work was to improve the tribological behaviour and lubricant properties using hybrid Cellulose Nanocrystal (CNC) and Copper (II) oxide nanoparticles blended with SAE 40 as a base fluid. The two-step method was used in the hybrid nanofluid preparation. Three different concentrations were prepared in a range of 0.1% to 0.5%. Kinematic viscosity and viscosity index were also identified. The friction and wear behavior were evaluated using a tribometer based on ASTM G181. The CNC-CuO nano lubricant shows a significant improvement in term of viscosity index by 44.3-47.12% while for friction, the coefficient of friction (COF) decreases by 1.5%, respectively, during high and low-speed loads (boundary regime), and 30.95% during a high-speed, and low load (mixed regime). The wear morphologies results also show that a smoother surface was obtained after using CNC-CuO nano lubricant compared to SAE 40.
    Matched MeSH terms: Surface Properties
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