MyMedR

Displaying publications 1 - 20 of 183 in total

Abstract:

Sort:

Fulltext Evaluating the clinical relevance of codon 594 (g>a) polymorphism of estrogen receptor alpha in knee osteoarthritis

Tawonsawatruk T, Mulpruek P, Hamilton D, Wajanavisit W, Tan S

Malays Orthop J, 2014 Mar;8(1):37-40.
PMID: 25347522 DOI: 10.5704/MOJ.1403.016

It has been reported that oestrogen receptor alpha (ER-α) polymorphisms are associated with knee osteoarthritis (OA). In this study, we assessed whether there was any association between the codon 594 (G>A) polymorphism in ER-α and radiographic features of OA or patient function. Radiographs, WOMAC score and patient reported time of symptom onset were assessed in 194 patients presenting for total knee replacement at Ramathibodi hospital over a one year period. ESR-1 genotyping was assessed. There were 107 (55.15%) patients with common homozygote (GG), 78 (40.20%) patients with heterozygote (GA) and nine (4.65%) patients with rare homozygote (AA). There was poor correlation (r = <0.2) between group difference in the radiographic parameters, time of onset of symptom , or in WOMAC scores. This polymorphism is not associated with the clinical features of knee osteoarthritis. The role of this polymorphism is unlikely then to be used as a biological marker predicting the progression of knee OA.

Matched MeSH terms: Osteoarthritis, Knee*
Fulltext Update on the management of osteoarthritis

Goh EML, Chow SK, Yeap SS

JUMMEC, 2002;7(2):86-91.

Osteoarthritis is the most common joint disorder in the human population. It is characterized by the destruction of articular cartilage and the overgrowth of marginal and subchondral bone. The commonest weight bearing joint affected is that of the knee, affecting over one third of people over Ihe age of 65 years. This article reviews the recent principles of non surgical management of osteoarthritis. This is divided into non drug management such as primary prevention, physiotherapy, occupational therapy and patient education. Drug management will include the use of different types of analgesics. viscosupplementation as well as joint injection. KEY WORDS: Osteoarthritis, management

Matched MeSH terms: Osteoarthritis
Fulltext A 62 year old man with pain and stiffness of hands

Das Gupta E

Malays Fam Physician, 2007;2(1):35.
PMID: 25606078
Matched MeSH terms: Osteoarthritis*
Fulltext Role of exercise in patients with symptomatic knee osteoarthritis

Koh KL

Malays Fam Physician, 2008;3(3):155.
PMID: 25606141
Matched MeSH terms: Osteoarthritis, Knee
Fulltext The past and current updates on diagnostic aspects of osteoarthritis

Tan WM, Lau SF, Ajat M, Mansor R, Abd-Rani PAM, Ng AMH, et al.

Jurnal Veterinar Malaysia, 2017;29(1):7-12.
MyJurnal

Osteoarthritis (OA) is a progressive joint disease leading to the destruction of joint structures, which in turn causes severe and chronic pain to the patient. Since OA is a troubling and disruptive disease, numerous researches have been done into diagnosing this disease, both in the early and the late stages of the disease. Diagnostic modalities such as radiography, computed-tomography (CT), micro-computed tomography (µ-CT), and magnetic resonance imaging (MRI) have been used in OA research. Not only that, more advance measurements and criteria have been established to standardize OA research. Currently, the OA research has been delving into proteomic studies to search for potential disease biomarkers. Biomarkers such as urinary C-terminal telopeptide of collagen type 2 (uCTX-II) and cartilage oligometric protein (COMP) have shown potential to be both diagnostic and prognostic biomarkers. For this review paper, the developments in diagnostic modalities are discussed focusing more on proteomic and biomarker studies.

Matched MeSH terms: Osteoarthritis
Current DMOAD options for the treatment of osteoarthritis

Yeap SS

Clin Exp Rheumatol, 2020 03 05;38(4):802.
PMID: 32141438
Matched MeSH terms: Osteoarthritis/drug therapy*; Osteoarthritis, Knee/drug therapy*
Fulltext Knee pain and functional disability of knee osteoarthritis patients seen at Malaysian government hospitals

Foo CN, Manohar A, Rampal L, Lye MS, Mohd Sidik S, Osman ZJ

Malaysian Journal of Medicine and Health Sciences, 2017;13(2):7-15.
MyJurnal

Introduction: Osteoarthritis (OA) is the main cause of knee pain. It also affects individual’s physical functioning. Anti- inflammatory drugs and knee replacement are the mainstay methods in the management of knee OA in Malaysia. However, patients with knee OA often suffer pain. The general objective of the study is to evaluate the effectiveness of a cognitive behavioural intervention module on knee pain, functional disability and psychological outcomes among knee OA patients attending Orthopedics Clinics in Hospital Putrajaya and Hospital Serdang, Malaysia. This study aims to determine the baseline level of knee pain and functional disability among knee OA patients.
Methods: Baseline results on the knee pain and functional disability were obtained from a two arm parallel- group randomized controlled study. Three hundred patients aged 35 to 75 years diagnosed with knee OA were recruited. A set of pre tested and validated Knee injury and Osteoarthritis Outcome Score (KOOS) questionnaire was used in this study.
Results: Mean baseline of KOOS pain was 56.09 (SD=21.75) and 52.26 (SD=22.08) for the intervention and control groups respectively. Participants in the intervention and control groups had a mean KOOS function in daily living of 61.11 (SD=21.20) and 56.72 (SD=22.13) respectively. Overall mean baseline of KOOS function in sport and recreation was 35.30 (SD=27.38).
Conclusions: Majority of participants had moderate level of knee pain and functional disability in daily living. However, participants had more extreme symptoms of functional disability in sport and recreation. Therefore, interventions to reduce knee pain and functional disability symptoms in knee OA are needed.

Study site: Orthopedics Clinics in Hospital Putrajaya and Hospital Serdang, Malaysia

Matched MeSH terms: Osteoarthritis, Knee*
The effects of Momordica charantia (bitter melon) supplementation in patients with primary knee osteoarthritis: A single-blinded, randomized controlled trial

Soo May L, Sanip Z, Ahmed Shokri A, Abdul Kadir A, Md Lazin MR

Complement Ther Clin Pract, 2018 Aug;32:181-186.
PMID: 30057048 DOI: 10.1016/j.ctcp.2018.06.012

BACKGROUND: Osteoarthritis is a common problem affecting the joints in the elderly, caused disability and consequently decrease the quality of life. The conservative treatment includes the usage of analgesia, but the use of herbal medicine is growing. Momordica charantia or bitter melon has been widely described to have anti-diabetic and anti-inflammatory effects. However, its effect on reducing pain in primary knee osteoarthritis is not well studied. We aim to determine the effects of Momordica charantia in reducing pain among primary knee osteoarthritis patients.
MATERIALS AND METHODS: Thirty-eight and thirty-seven primary knee osteoarthritis patients underwent 3 months of Momordica charantia and placebo supplementation respectively. Three 500 mg per capsule of Momordica charantia were taken thrice daily. Rescue analgesia was allowed as needed. Pain and symptoms throughout the Momordica charantia supplementation period were assessed using Knee Injury and Osteoarthritis Outcome Score and EQ-5D-3L Health questionnaire, while rescue analgesia intake throughout the period of supplementation was measured using analgesic score.
RESULTS: After 3 months supplementation period, body weight, body mass index, and fasting blood glucose reduced significantly in the Momordica charantia group. There were also significant improvements in Knee Injury and Osteoarthritis Outcome Score subscales and EQ-5D-3L dimension score, and reduction in analgesic score. The placebo group had also shown significant improvements in certain Knee Injury and Osteoarthritis Outcome Score subscales and EQ-5D-3L dimension score, but with increased of the analgesic score.
CONCLUSION: Momordica charantia supplementation offers a safe alternative to reducing pain and improving symptoms among the primary knee osteoarthritis patients while reducing the need for analgesia consumption. These beneficial effects can be seen as early as 3 months of supplementation.
Study site: Orthopaedic clinic, Hospital Universiti Sains Malaysia (HUSM), Kelantan, Malaysia

Matched MeSH terms: Osteoarthritis, Knee*
Fulltext Knee associated problems and functional mobility among adults with knee osteoarthritis. [Abstract]

Ajit Singh DK, Ngu ACY, Ahmad MA, Mohd Padzil FA, Hendri ENM, Kamsan SS

Jurnal Sains Kesihatan Malaysia, 2018;16(101):229-230.
MyJurnal

Knee osteoarthritis (KOA) is a major cause of disability and significantly reduce quality of life (QOL). There is limited information about knee associated problems and functional mobility among Malaysian adults with KOA. The aim of our study was to examine knee associated problems and functional mobility among this population. Forty-five (45) adults with KOA with mean age of 65.02 ± 8.083 were recruited from Hospital Canselor Tuanku Muhriz, UKM. Knee associated problems and functional mobility were measured using Knee injury and Osteoarthritis Outcome Scores (KOOS) and Timed-Up and Go (TUG) test respectively. The mean score and standard deviation for TUG test was 11.44 ± 2.69 seconds. Median scores (with interquartile ranges [IQR]) for the KOOS subscale domains were; Symptoms: 80.56, (69.44 to 91.67); Pain: 71.43 (50 to 78.57); Functional Activities of Daily Living: 82.3 (67.65 to 86.76); Sports and Recreation Function: 30 (20 to 60); and Knee-Related Quality of Life: 50 (25 to 75). Generally, participants’ TUG test performance showed that time taken to complete the test was higher than the reference values (7.14 to 8.43 seconds) identified among Malaysian community dwelling older adults with low to high risk of falls. The KOOS scores in adults with KOA in our study is similar to previous reports with Sport and Recreation Function and QOL domains been the most affected. It is important to improve functional mobility and balance in order to decrease falls risk and optimise sport and recreation function and QOL among adults with KOA.
Study site: Pusat Perubatan Universiti Kebangsaan Malaysia (PPUKM), Kuala Lumpur, Malaysia

Matched MeSH terms: Osteoarthritis, Knee*
Fulltext Popliteal artery to tibial plateau distance at the knee level: a radiological study to assess injury risks in osteoarthritic knees using dual source dual energy CT scan

Ezamin, A.R., Hasyma, A.H., Suppiah, S., Suraini, M.S., Arifaizad, A., Paisal, Hussin, et al.

Pertanika Journal of Science & Technology, 2017;25(1):371-378.
MyJurnal

Popliteal artery injury is the most disastrous intraoperative complication during total knee replacement. This study aims to determine the mean distance between the popliteal artery (PA) and the tibial plateau in normal and osteoarthritic patients who underwent Dual Energy CT Angiography (CTA) of the lower limb.
Materials and Methods: All CTA lower limb examinations from January 2013 to October 2014 were retrospectively reviewed. The distance between the PA the tibial plateau distance and the thickness of popliteus muscle were electronically measured. We used modified Kellgren and Lawrence’s Classification to grade the osteoarthritis in patients who underwent CT examinations regardless of symptoms.
Results: There were a total of 126 patients who underwent CTA (93 males and 33 females). 54 of them were Malays, 47 Indians, and 24 Chinese. The mean age of patients was 58 years (range 16 to 92). The mean PA-totibial plateau distance was 9.9 mm for the right lower limb (range 2.5 mm to 17.2 mm) and 10.24 mm for the left (range 5.5 mm to 15.4 mm). There were no significant correlations between PA-to-tibial plateau distance with osteoarthritis grade, age, gender, and racial origin (P > 0.05); however, there was a positive
correlation between PA-to-tibial plateau distances with popliteus muscle thickness (P = 0.000).
Conclusion: Osteoarthritic condition in the knee does not reduce the popliteal artery to the tibial plateau distance. Hence, a higher osteoarthritic grade does not impose additional risks with regards to popliteal artery to tibial plateau distance, with relatively similar arterial injury risks compared to normal knees.

Matched MeSH terms: Osteoarthritis, Knee*
Fulltext Using Design of Experiments Methods for Assessing Peak Contact Pressure to Material Properties of Soft Tissue in Human Knee

Bahraminasab M, Jahan A, Sahari B, Arumugam M, Shamsborhan M, Hassan MR

J Med Eng, 2013;2013:891759.
PMID: 27006925 DOI: 10.1155/2013/891759

Contact pressure in the knee joint is a key element in the mechanisms of knee pain and osteoarthritis. Assessing the contact pressure in tibiofemoral joint is a challenging mechanical problem due to uncertainty in material properties. In this study, a sensitivity analysis of tibiofemoral peak contact pressure to the material properties of the soft tissue was carried out through fractional factorial and Box-Behnken designs. The cartilage was modeled as linear elastic material, and in addition to its elastic modulus, interaction effects of soft tissue material properties were added compared to previous research. The results indicated that elastic modulus of the cartilage is the most effective factor. Interaction effects of axial/radial modulus with elastic modulus of cartilage, circumferential and axial/radial moduli of meniscus were other influential factors. Furthermore this study showed how design of experiment methods can help designers to reduce the number of finite element analyses and to better interpret the results.

Matched MeSH terms: Osteoarthritis
Fulltext The levels of depression, anxiety, stress on pre and post knee Arthroplasty patients

Ardilla Hanim Abdul Razak, Ahmad Hafiz Zulkifly, Ramli Musa, Mohd Shukrimi Awang, Goh, Kian Liang

International Medical Journal Malaysia, 2017;16(11):39-39.
MyJurnal

Total knee arthroplasty represents a major advance in the treatment of
degenerative joint disease. It provides excellent restoration of joint function and pain
relief. The primary indication for total knee arthroplasty is to relieve pain caused by
severe arthritis, with or without significant deformity. This study is to assess
psychological impact pre and post arthroplasty. (Copied from article).

Matched MeSH terms: Osteoarthritis
Systematic review and meta-analysis of the prevalence of neuropathic-like pain and/or pain sensitization in people with knee and hip osteoarthritis

Zolio L, Lim KY, McKenzie JE, Yan MK, Estee M, Hussain SM, et al.

Osteoarthritis Cartilage, 2021 08;29(8):1096-1116.
PMID: 33971205 DOI: 10.1016/j.joca.2021.03.021

OBJECTIVE: To determine the prevalence of neuropathic-like pain (NP) and pain sensitization (PS) defined by self-report questionnaires in knee and hip osteoarthritis, and whether prevalence is potentially explained by disease-severity or affected joint.
DESIGN: MEDLINE, EMBASE, CINAHL were systematically searched (1990-April 2020) for studies describing the prevalence of NP and PS in knee and hip osteoarthritis using self-report questionnaires. Random-effects meta-analysis was performed. Statistical heterogeneity between studies and sub-groups (affected joint and population source as a proxy for disease severity) was assessed (I2 statistic and the Chi-squared test).
RESULTS: From 2,706 non-duplicated references, 39 studies were included (2011-2020). Thirty-six studies reported on knee pain and six on hip pain. For knee osteoarthritis, the pooled prevalence of NP was: using PainDETECT, possible NP(score ≥13) 40% (95%CI 32-48%); probable NP(score >18) 20% (95%CI 15-24%); using Self-Report Leeds Assessment of Neuropathic Symptoms and Signs, 32% (95%CI 26-38%); using Douleur Neuropathique (DN4) 41% (95% CI 24-59%). The prevalence of PS using Central Sensitization Inventory (CSI) was 36% (95% CI 12-59%). For hip osteoarthritis, the pooled prevalence of NP was: using PainDETECT, possible NP 29% (95%CI 22-37%%); probable NP 9% (95%CI 6-13%); using DN4 22% (95%CI 12-31%) in one study. The prevalence of possible NP pain was higher at the knee (40%) than the hip (29%) (difference 11% (95% CI 0-22%), P = 0.05).
CONCLUSIONS: Using self-report questionnaire tools, NP was more prevalent in knee than hip osteoarthritis. The prevalence of NP in knee and hip osteoarthritis were similar for each joint regardless of study population source or tool used. Whether defining NP using self-report questionnaires enables more effective targeted therapy in osteoarthritis requires investigation.

Matched MeSH terms: Osteoarthritis, Hip/physiopathology*; Osteoarthritis, Knee/physiopathology*
Exploring predictors of physical dysfunction associated with proprioception in Malaysian elderly individuals suffering from osteoarthritis of knee

Bhaskar Raj N, Saha S, Saha S, Hashim HA, Mohd Zahir NEB, Huda F

International Medical Journal (Tokyo), 2017;24(3):260-263.

Background: This study was done to identify the problems associated with physical dysfunction in relation to proprioception in osteoarthrosis (OA) of knee. OA is a degenerative joint disorder, which commonly occurs in knee of middle aged and elderly patients, with a high prevalence rate amongst individuals with higher body-mass index. As the Community Orientated Program for Control of Rheumatic Diseases (COPCORD) reported that, 23% of Malaysians aging more than 55 yrs. and 39% of those aged more than 65 yrs. complained of sharp increase in knee pain.
Materials and Methods: From a pool of six-hundred ninety-seven elderly individuals suffering from pain in knee, four-hundred forty-four individuals (two hundred fifty-three females and one-hundred ninety-one male patients) aging between fifty-six to sixty-five years were selected on the basis of Kellgren's (Grade - II) criteria of deficit in proprioception. Participants were subjected to assessment of body-composition analyses using the BOD-POD analyser. Extent of proprioception was evaluated by the Isokinetic device and problems associated with stiffness were evaluated by the 3D motion tracking system.
Results: Following WOMAC assessment protocol, extent of difficulties associated with knee pain was evaluated. Regression analyses reports however revealed that, taller old individuals, if had higher BMI & higher extent of stiffness, were evident as having most difficulty in proprioception.
Conclusion: Significance of perceived stiffness was evident, which in association with different metabolic indices emerged as significant predictor of deficient proprioception and related knee osteoarthrosis. © 2017 Japan Health Sciences University & Japan International Cultural Exchange Foundation.

Matched MeSH terms: Osteoarthritis, Knee*
Fulltext Knee osteoarthritis and its related issues: patients’ perspective

Ahmad MA, Ajit Singh DK, Chua WQ, Abd Rahman NNA, Mohd Padzil FA, Hendri ENM

Jurnal Sains Kesihatan Malaysia, 2018;16(101):171-177.
MyJurnal

Knee osteoarthritis (OA) is a common chronic joint disease that results in pain and disability in many people. Cultural practice may influence patients’ views about their condition, its related issues and management. The aim of our study was to explore the perspective about knee OA and its related issues among Malaysian patients with knee OA. Twelve patients diagnosed with knee OA (8 females and 4 males) attending physiotherapy sessions at a University Hospital, mean age (SD): 67.1(9.4) years and median visual analog scale score of 5/10 participated in this qualitative study. One to one in-depth interviews were conducted, audio recorded and later transcribed verbatim. Three main themes were identified from the transcribed data; knee pain and its’ related issues (reason and aggravating factors of knee pain, coping strategies), impact of knee pain (impact on daily activities and emotions) and physiotherapy management (effects and expectations of physiotherapy, compliance and adherence towards home exercises). Most participants expressed that their knee pain was aggravated by certain movements that had an effect on their daily activities namely squatting. The findings also suggested that physiotherapy management was perceived as secondary prevention rather than a cure. Findings from this study provides information about the perceptions and related issues of patients with knee OA. This information may help health professionals in tailoring patient-centered care and provide better management.
Study site: Physiotherapy department, Pusat Perubatan Universiti Kebangsaan Malaysia (PPUKM), Kuala Lumpur, Malaysia

Matched MeSH terms: Osteoarthritis, Knee*
Fulltext Cost-effectiveness of surgical interventions for the management of osteoarthritis: a systematic review of the literature

Kamaruzaman H, Kinghorn P, Oppong R

BMC Musculoskelet Disord, 2017 05 10;18(1):183.
PMID: 28486957 DOI: 10.1186/s12891-017-1540-2

BACKGROUND: The primary purpose of this study is to assess the existing evidence on the cost-effectiveness of surgical interventions for the management of knee and hip osteoarthritis by systematically reviewing published economic evaluation studies.

METHODS: A systematic review was conducted for the period 2004 to 2016. Electronic databases were searched to identify both trial and model based economic evaluation studies that evaluated surgical interventions for knee and hip osteoarthritis.

RESULTS: A total of 23 studies met the inclusion criteria and an assessment of these studies showed that total knee arthroplasty (TKA), and total hip arthroplasty (THA) showed evidence of cost-effectiveness and improvement in quality of life of the patients when compared to non-operative and non-surgical procedures. On the other hand, even though delaying TKA and THA may lead to some cost savings in the short-run, the results from the study showed that this was not a cost-effective option.

CONCLUSIONS: TKA and THA are cost-effective and should be recommended for the management of patients with end stage/severe knee and hip OA. However, there needs to be additional studies to assess the cost-effectiveness of other surgical interventions in order for definite conclusions to be reached.

Matched MeSH terms: Osteoarthritis, Hip/economics*; Osteoarthritis, Hip/surgery; Osteoarthritis, Knee/economics*; Osteoarthritis, Knee/surgery
Fulltext Adaptation and validation of the malay version of the Osteoarthritis Knee and Hip Quality of Life Questionnaire among knee osteoarthritis patients

Abdul Kadir A, Mohd Arif MF, Ishak A, Hassan II, Mohd Noor N

Biomed Res Int, 2018;2018:4329751.
PMID: 29955601 DOI: 10.1155/2018/4329751

Objective: To adapt and validate the Malay version of Osteoarthritis Knee and Hip Quality of Life (OAKHQOL) questionnaire.

Design: The OAKHQOL was adapted into Malay version using forward-backward translation methodology. It was then validated in a cross-sectional study of 191 patients with knee osteoarthritis (OA). Patients completed the OAKHQOL and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire. Confirmatory analysis, reliability analysis, and Pearson correlation test were performed.

Results: The new five-factor model of 28 items demonstrated an acceptable level of goodness of fit (comparative fit index = 0.915, Tucker-Lewis index = 0.905, incremental fit index = 0.916, chi-squared/degree of freedom = 1.953, and root mean square error of approximation = 0.071), signifying a fit model. The Cronbach's alpha value and the composite reliability of each construct ranged from 0.865 to 0.933 and 0.819 to 0.921, respectively. The Pearson correlation coefficient between the OAKHQOL and the WOMAC showed adequate criterion validity. Known groups validity showed statistical difference in body mass index in physical activity, mental health, and pain construct. The pain domain was statistically different between the age groups.

Conclusion: The Malay version OAKHQOL questionnaire is a valid and reliable instrument to assess health-related quality of life in knee OA patients.

Matched MeSH terms: Osteoarthritis, Hip*; Osteoarthritis, Knee*; Osteoarthritis, Knee/complications*
Fulltext Influence of hip and knee osteoarthritis on dynamic postural control parameters among older fallers

Mat S, Ng CT, Tan MP

J Rehabil Med, 2017 Mar 06;49(3):258-263.
PMID: 28218341 DOI: 10.2340/16501977-2202

OBJECTIVE: To compare the relationship between postural control and knee and hip osteoarthritis in older adults with and without a history of falls.
METHODS: Fallers were those with ≥ 2 falls or 1 injurious fall over 12 months. Non-fallers were volunteers with no falls in the past year. Radiological evidence of osteoarthritis with no reported symptoms was considered "asymptomatic osteoarthritis", while "symptomatic osteoarthritis" was defined as radiographic osteoarthritis with pain or stiffness. Dynamic postural control was quantified with the limits of stability test measured on a balance platform (Neurocom® Balancemaster, California, USA). Parameters assessed were end-point excursion, maximal excursion, and directional control.
RESULTS: A total of 102 older individuals, mean age 73 years (standard deviation 5.7) years were included. The association between falls and poor performance in maximal excursion and directional control was confounded by age and comorbidities. In the same linear equation model with falls, symptomatic osteoarthritis remained independently associated with poor end-point excursion (β-coefficient (95% confidence interval) -6.80 (-12.14 to -1.42)).
CONCLUSION: Poor performance in dynamic postural control (maximal excursion and directional control) among fallers was not accounted for by hip/knee osteoarthritis, but was confounded by old age and comorbidities. Loss of postural control due to hip/knee osteoarthritis is not a risk factor for falls among community-dwelling older adults.
Study site: Departments of Emergency Medicine, Primary Care and Geriatric Medicine, in a teaching hospital in Kuala Lumpur, Malaysia

Matched MeSH terms: Osteoarthritis, Hip/complications; Osteoarthritis, Hip/physiopathology*; Osteoarthritis, Knee/complications; Osteoarthritis, Knee/physiopathology*
Comparing exercise prescription methods in knee osteoarthritis patients in Malaysia

D'Gasper D, Bains BS, Sadeghi H, Kumar P

Acta Medica Bulgarica, 2018;45(1):26-31.
DOI: 10.2478/amb-2018-0005

Aim: This study was a qualitative study that investigated the exercise prescription method in knee osteoarthritis patients in Malaysia. It purposed to find out the most common and effective method used by physiotherapist in prescribing exercises for knee osteoarthritis patients in Malaysia.
Method: This study used a self-administered survey questionnaire. The subjects recruited for this study were diagnosed with knee osteoarthritis, age range of between 50 to 80 years old.The methods of delivery were divided into three categories, which include only verbal instructions, verbal instruction together with demonstration and lastly a combination of all three methods including verbal instruction, demonstration and handouts with diagrams.
Results: The results showed that 52% received their exercise prescription with verbal instruction and together with demonstration, about 43% of them received all three types of methods which included the verbal instruction, demonstration and take home handouts and 5% of them only received verbal instruction. Out of 5% who received verbal instruction alone, only 1% understood the exercises and the remaining 4% did not and 45% out of 52% who received verbal and demonstration method understood the exercises and the remaining 7% did not. 5% who received only verbal instruction did not seem to continue the exercises at home. 52% received verbal instruction together with demonstration, with about 44% of them having continued their exercises but the remaining 8% did not. 43% who received all three methods reported to continue.
Conclusion: The best method of delivering exercises to knee osteoarthritis patients was proven to be the method with a combination of verbal instruction, demonstration together with a take home handout. This method showed very positive outcome and should be implemented and emphasized more in both the government and private sectors of physiotherapy departments.

Matched MeSH terms: Osteoarthritis, Knee*
Fulltext Intra-articular hyaluronic acid (HA) and platelet rich plasma (PRP) injection versus hyaluronic acid (HA) injection alone in patients with grade III and IV knee osteoarthritis (OA): a retrospective study on functional outcome

Saturveithan C, Premganesh G, Fakhrizzaki S, Mahathir M, Karuna K, Rauf K, et al.

Malays Orthop J, 2016 Jul;10(2):35-40.
PMID: 28435559 MyJurnal DOI: 10.5704/MOJ.1607.007

Introduction: Intra-articular hyaluronic acid (HA) is widely utilized in the treatment of knee osteoarthritis whereas platelet rich plasma (PRP) enhances the regeneration of articular cartilage. This study analyses the efficacy of HA and PRP in grade III and IV knee osteoarthritis. Methodology: This is a cross sectional study with retrospective review of 64 patients (101 knees) which includes 56 knees injected with HA+ PRP, and 45 knees with HA only. Results: During the post six months International Knee Documentation Committee (IKDC) evaluation, HA+PRP group showed marked improvement of 24.33 compared to 12.15 in HA group. Decrement in visual analogue score (VAS) in HA+PRP was 1.9 compared to 0.8 in HA group. Conclusion: We propose intra-articular HA and PRP injections as an optional treatment modality in Grade III and IV knee osteoarthritis in terms of functional outcome and pain control for up to six months when arthroplasty is not an option.
Study site: Melaka General Hospital, Malaysia

Matched MeSH terms: Osteoarthritis, Knee*

Filters

Please provide feedback to Administrator (afdal@afpm.org.my)

External Links