Browse publications by year: 2023

  1. Thomas DC, Nain RA
    Data Brief, 2023 Jun;48:109193.
    PMID: 37213558 DOI: 10.1016/j.dib.2023.109193
    Pressure injuries are a significant problem in healthcare, and understanding the knowledge and practices of nurses in this area is critical to improving patient outcomes. This article presents dataset concerning a survey conducted to assess the knowledge, attitudes, and practices of pressure injury prevention and care among nurses in public hospitals in the West Coast division of Sabah, Malaysia. The study involved 448 nurses who completed a structured questionnaire between April and December 2021, using the Malay version of the Pieper-Zulkowski-Pressure Ulcer Knowledge Test (PZ-PUKT) 2016 questionnaire. The questionnaire included socio-demographic information and three outcome measures related to pressure injury prevention. Quantitative descriptive statistical analysis was used to analyze the survey results. The data suggest that this survey provides insights into nurses' knowledge, attitudes, and practices regarding pressure injury prevention and could inform the development of interventions to improve the prevention and management of pressure injuries in public hospitals.
  2. Wong LP, Alias H, Farid NDN, Yusop SM, Musa Z, Hu Z, et al.
    Front Public Health, 2023;11:1158698.
    PMID: 37213607 DOI: 10.3389/fpubh.2023.1158698
    INTRODUCTION: This study aims to shed light on parent-child relationships and the psychological health of parents from low-income families after the easing of the COVID-19 pandemic restrictions.

    METHODS: This cross-sectional study recruited 553 parents of children aged 13-24 years in low-income community settings. The Parent-Child Conflict scale of the Parental Environment Questionnaire (PEQ) was used to measure parent-child conflict. Psychological distress was assessed using the Depression, Anxiety, and Stress Scale short form (DASS-21).

    RESULTS: The study revealed a low level of parent-child conflict in the overall study population, with a median PEQ of 48.0 (interquartile range [IQR] 36 to 48). Concerning demographics, married parents reported a likelihood of having a higher level of parent-child conflict over 3 times higher than single parents (OR = 3.18 95%, CI 1.30-7.75). More parent-child conflicts were also found in parents aged 60-72 years old who were unemployed, retired, or housewives and from lower-income groups. In regard to lifestyle factors, a higher level of physical activity and having enough sleep were associated with lower levels of parent-child conflict. Only approximately 1% of the participants reported symptoms of depression, anxiety, or stress.

    DISCUSSION: Low risk exists for parent-child conflict and psychological sequelae following the easing of the COVID-19 pandemic restrictions, which could be due to various support measures implemented by the government. Vulnerable parents identified as being at risk of parent-child conflict warrant attention in future advocacy efforts.

    MeSH terms: Adolescent; Adult; Aged; Child; Female; Humans; Malaysia/epidemiology; Male; Middle Aged; Parent-Child Relations*; Parents; Poverty; Surveys and Questionnaires; Residence Characteristics; Stress, Psychological; Infection Control*; Family Conflict; Pandemics*
  3. Caron RM, Jamshed SQ, Goodman MS, Kang S
    Front Public Health, 2023;11:1204113.
    PMID: 37213627 DOI: 10.3389/fpubh.2023.1204113
    MeSH terms: Female; Health Education*; Health Promotion*; Humans
  4. Mohamed W
    Am J Neurodegener Dis, 2023;12(2):23-41.
    PMID: 37213711
    Parkinson's disease (PD), the most common motoric neurodegenerative illness, has been extensively researched to better understand its complex pathophysiology. Nearly 80% of genome-wide association studies have been conducted on persons of European ancestry, indicating a lack of diversity in human genetics. Disparate representation may result in disparities that impede the equitable adoption of personalized medicine and may also limit our knowledge of illness etiology. Even though Parkinson's disease (PD) is a global affliction, the AfrAbia population remains understudied. We conducted a dynamic and longitudinal bibliometric analysis to investigate existing studies on Parkinson's disease genetics in the AfrAbia area and identify data gaps and possible new research avenues. All PD papers concentrating on PD genetics were found using the search terms "Parkinson's Disease", "Genetics", and "Africa" in the PubMed/MEDLINE database. Only English publications published between 1992 and 2023 were chosen using filters. Original English-language research publications disclosing genetic results on Parkinson's disease in non-European Africans were examined for inclusion. Two sets of independent reviewers discovered and extracted pertinent data. The bibliometric study was carried out using the R software packages Bibliometrix and Biblioshiny. The narrowed search yielded 43 publications, all published between 2006 and 2022. Yet, after applying filters and considering the inclusion requirements, the search results comprise just 16 original articles out of 43 articles. There were 27 articles eliminated. This study puts emphasis on the critical need for more diverse participant demographics in Parkinson's disease investigations. AfrAbia-PD-Genetic Consortium (AAPDGC) is GP2 initiative that helps to represent AfrAbia PD genetics.
  5. Azis KA, Al-Chalabi MMM, Mat Johar SFN, Wan Sulaiman WA
    Cureus, 2023 Apr;15(4):e37751.
    PMID: 37214021 DOI: 10.7759/cureus.37751
    Breast implant surgery typically improves patient breast satisfaction and health-related quality of life. However, breast implants are also linked to long-term local problems like capsular contracture and breast discomfort. Chest pain is one of the reasons that patients with breast implants seek consultations, which is not typically attributable to cardiovascular reasons. The potential reasons for atypical chest pain are diverse. The absence of a precise diagnosis may also result in incorrect examinations and management, leading to further worry and wasted work time. A 55-year-old woman with a breast implant 10 years prior to the incident, presented with atypical chest pain on and off for a year and was treated as a case of unstable angina, costochondritis, and vasospastic spasm. Despite multiple visits, her symptoms did not resolve. Later, the patient presented with a lump over the left breast, associated with constitutional symptoms. Examination revealed a left breast implant with capsular contracture grade III, and ultrasonography showed signs of a ruptured implant. Symptoms eventually resolved after the removal of the breast implant.
  6. Ng HK, Puah SM, Teh CSJ, Idris N, Chua KH
    PeerJ, 2023;11:e15304.
    PMID: 37214089 DOI: 10.7717/peerj.15304
    BACKGROUND: Acinetobacter baumannii was reported to have resistance towards carbapenems and the ability to form an air-liquid biofilm (pellicle) which contributes to their virulence. The GacSA two-component system has been previously shown to play a role in pellicle formation. Therefore, this study aims to detect the presence of gacA and gacS genes in carbapenem-resistant Acinetobacter baumannii (CRAB) isolates recovered from patients in intensive care units and to investigate their pellicle forming ability.

    METHODS: The gacS and gacA genes were screened in 96 clinical CRAB isolates using PCR assay. Pellicle formation assay was performed in Mueller Hinton medium and Luria Bertani medium using borosilicate glass tubes and polypropylene plastic tubes. The biomass of the pellicle was quantitated using the crystal violet staining assay. The selected isolates were further assessed for their motility using semi-solid agar and monitored in real-time using real-time cell analyser (RTCA).

    RESULTS: All 96 clinical CRAB isolates carried the gacS and gacA genes, however, only four isolates (AB21, AB34, AB69 and AB97) displayed the ability of pellicle-formation phenotypically. These four pellicle-forming isolates produced robust pellicles in Mueller Hinton medium with better performance in borosilicate glass tubes in which biomass with OD570 ranging from 1.984 ± 0.383 to 2.272 ± 0.376 was recorded. The decrease in cell index starting from 13 hours obtained from the impedance-based RTCA showed that pellicle-forming isolates had entered the growth stage of pellicle development.

    CONCLUSION: These four pellicle-forming clinical CRAB isolates could be potentially more virulent, therefore further investigation is warranted to provide insights into their pathogenic mechanisms.

    MeSH terms: beta-Lactamases/genetics; Humans; Microbial Sensitivity Tests; Carbapenems/pharmacology
  7. Teo SH, Ong TK, Merican AM, Hashim MS, Ng WM, Al-Fayyadh MZM, et al.
    Indian J Orthop, 2023 Jun;57(6):847-855.
    PMID: 37214363 DOI: 10.1007/s43465-023-00874-x
    BACKGROUND: Accurate planning for patellar instability correction is important in obtaining good post-operative outcome. The main challenge in the current two-dimensional (2-D) computed tomographic (CT) scans method is the difficulty in choosing reliable bony landmarks. This study aimed to compare the reliabilities between the 2-D and three-dimensional (3-D) methods of measuring tibial tubercle-trochlear groove (TT-TG) distance. We hypothesize that the proposed 3-D method will result in measurements with narrower error margin, providing higher reliability and accuracy.

    MATERIALS AND METHODS: We traced CT scans of 106 knees with no patellofemoral pathology from 59 subjects from the database system and converted all 2-D images into 3-D models to determine the values for each parameter. We compared the intra- and interobserver reliability of each method using intraclass correlation (ICC) and Bland-Altman method.

    RESULTS: The values of TT-TG measured by 2-D and 3-D methods were 16.1 ± 4.6 mm and 16.2 ± 4.2 mm, respectively. The ICC values of both methods were comparable (95% limits of agreement between the same observer: - 3.3 to 3.8 mm versus - 2.4 to 2.7 mm and different observers: - 4.3 to 4.9 mm versus - 3.9 to 2.7 mm), with 3-D method results in narrower limits of agreement.

    CONCLUSION: TT-TG measurement is reliable using the 2-D method without using advanced radiographic software. The 3-D method of measuring TT-TG provides measurement with narrower variation when compared with the 2-D method. However, both TT-TG distances' measurement methods in the current study were comparable as the variations are not significant.

  8. Mansour NO, Elnaem MH, Abdelaziz DH, Barakat M, Dehele IS, Elrggal ME, et al.
    Front Pharmacol, 2023;14:1185277.
    PMID: 37214454 DOI: 10.3389/fphar.2023.1185277
    Objectives: Traumatic brain injury (TBI) is one of the top causes of morbidity and mortality worldwide. The review aimed to discuss and summarize the current evidence on the effectiveness of adjuvant neuroprotective treatments in terms of their effect on brain injury biomarkers in TBI patients. Methods: To identify relevant studies, four scholarly databases, including PubMed, Cochrane, Scopus, and Google Scholar, were systematically searched using predefined search terms. English-language randomized controlled clinical trials reporting changes in brain injury biomarkers, namely, neuron-specific enolase (NSE), glial fibrillary acid protein (GFAP), ubiquitin carboxyl-terminal esterase L1 (UCHL1) and/or S100 beta (S100 ß), were included. The methodological quality of the included studies was assessed using the Cochrane risk-of-bias tool. Results: A total of eleven studies with eight different therapeutic options were investigated; of them, tetracyclines, metformin, and memantine were discovered to be promising choices that could improve neurological outcomes in TBI patients. The most utilized serum biomarkers were NSE and S100 ß followed by GFAP, while none of the included studies quantified UCHL1. The heterogeneity in injury severity categories and measurement timing may affect the overall evaluation of the clinical efficacy of potential therapies. Therefore, unified measurement protocols are highly warranted to inform clinical decisions. Conclusion: Few therapeutic options showed promising results as an adjuvant to standard care in patients with TBI. Several considerations for future work must be directed towards standardizing monitoring biomarkers. Investigating the pharmacotherapy effectiveness using a multimodal biomarker panel is needed. Finally, employing stratified randomization in future clinical trials concerning potential confounders, including age, trauma severity levels, and type, is crucial to inform clinical decisions. Clinical Trial Registration: [https://www.crd.york.ac.uk/prospero/dis], identifier [CRD42022316327].
  9. Kamimura Y, Lee CY, Yamasako J, Nishikawa M
    Zookeys, 2023;1146:115-134.
    PMID: 37214591 DOI: 10.3897/zookeys.1146.98248
    Euborellia (Anisolabididae: Anisolabidinae) is one of the most speciose genera of earwigs (Dermaptera), and its species-level classification is difficult. To settle the classification of brachypterous species with abbreviated tegmina recorded from East and Southeast Asia, we examined the morphology and reproductive isolation of three tentative Euborellia species, and analyzed the DNA barcoding region of the mitochondrial cytochrome oxidase subunit I (COI) gene. The observed complete reproductive isolation among the three Euborellia taxa and considerable differentiation in the COI sequences clearly show that each should be treated as a separate species. Based on morphology, distribution and the DNA sequence, we identify Euborellia sp. 1 of Malaysia as E.annulata (Fabricius), a circumtropical cosmopolitan with no records of a fully winged form. Samples from Ioto Island (= Iwo-jima Island: Ogasawara Islands, southern Japan) were also identified as this species. Euborellia sp. 3, from the main islands of Japan, was generally larger and lacked a Y-shaped pigmented area on the penis lobe, which is characteristic of Euborellia sp. 1. We propose reinstating E.pallipes (Shiraki) as the oldest name for this taxon. Euborellia sp. 2, even the brachypterous form, can be distinguished from these two species by its paler coloration (particularly the femora), ecarinate post-abdomen, and the shape of the male genitalia (parameres). We tentatively identify this species as E.philippinensis Srivastava based on the morphology of the brachypterous form, although the macropterous form cannot be distinguished from E.femoralis (Dohrn).
  10. Mohamad Nor N, Nasrul SN, Zakaria ND, Abdul Razak K
    ACS Omega, 2023 May 16;8(19):16587-16599.
    PMID: 37214679 DOI: 10.1021/acsomega.2c07085
    In this work, indium tin oxide (ITO) electrodes were functionalized with varying 3-aminopropyltriethoxysilane (APTES) concentration percentages (0.5, 0.75, 1.0, and 2.0 wt %) to obtain the optimum conditions for the assembly of the as-synthesized gold nanoparticles (AuNPs). The AuNP coverage, wettability, and electrochemical performance of the modified electrodes were evaluated. The AuNP/0.75% APTES-ITO-modified electrode exhibited uniform coverage of AuNPs and high electrochemical performance for the simultaneous detection of Cd(II), Pb(II), and Cu(II) ions. Under the optimum conditions, the AuNP/0.75% APTES-ITO-modified electrode showed a linear detection range of 5-120 ppb and limit of detection of 0.73, 0.90, and 0.49 ppb for the simultaneous detection of Cd(II), Pb(II), and Cu(II) ions, respectively, via square wave anodic stripping voltammetry. The modified electrode demonstrated good anti-interference toward other heavy metal ions, good reproducibility, and suitability for application in environmental sample analysis.
  11. Hussain S, Javed W, Tajammal A, Khalid M, Rasool N, Riaz M, et al.
    ACS Omega, 2023 May 16;8(19):16600-16611.
    PMID: 37214690 DOI: 10.1021/acsomega.2c06785
    Current studies were performed to investigate the phytochemistry, synergistic antibacterial, antioxidant, and hemolytic activities of ethanolic and aqueous extracts of Azadirachta indica (EA and WA) and Cymbopogon citratus (EC and WC) leaves. Fourier transform infrared data verified the existence of alcoholic, carboxylic, aldehydic, phenyl, and bromo moieties in plant leaves. The ethanolic extracts (EA and EC) were significantly richer in phenolics and flavonoids as compared to the aqueous extracts (WA and WC). The ethanolic extract of C. citratus (EC) contained higher concentrations of caffeic acid (1.432 mg/g), synapic acid (6.743 mg/g), and benzoic acid (7.431 mg/g) as compared to all other extracts, whereas chlorogenic acid (0.311 mg/g) was present only in the aqueous extract of A. indica (WA). Food preservative properties of C. citratus can be due to the presence of benzoic acid (7.431 mg/g). -Gas chromatography-mass spectrometry analysis demonstrated the presence of 36 and 23 compounds in A. indica and C. citratus leaves, respectively. Inductively coupled plasma analysis was used to determine the concentration of 26 metals (Al, As, B, Ba, Ca, Cd, Co, Cr, Cu, Fe, K, Mg, Mn, Mo, Na, Ni, Pb, Sb, Se, Si, Sn, Sr, V, Zn, Zr, Ti); the metal concentrations were higher in aqueous extracts as compared to the ethanolic extracts. The extracts were generally richer in calcium (3000-7858 ppm), potassium (13662-53,750 ppm), and sodium (3181-8445 ppm) and hence can be used in food supplements as a source of these metals. Antioxidant potential (DDPH method) of C. citratus ethanolic extract was the highest (74.50 ± 0.66%), whereas it was the lowest (32.22 ± 0.28%) for the aqueous extract of A. indica. Synergistic inhibition of bacteria (Staphylococcus aureus and Escherichia coli) was observed when the aqueous extracts of both the plants were mixed together in certain ratios (v/v). The highest antibacterial potential was exhibited by the pure extract of C. citratus, which was even higher than that of the standard drug (ciprofloxacin). The plant extracts and their mixtures were more active against S. aureus as compared to E. coli. No toxic hemolytic effects were observed for the investigated extracts indicating their safe medicinal uses for human beings.
  12. Ramalingam K, Vellaiyan S, Venkatesan EP, Khan SA, Mahmoud Z, Saleel CA
    ACS Omega, 2023 May 16;8(19):16545-16560.
    PMID: 37214702 DOI: 10.1021/acsomega.3c00387
    Under the roof of solid industrialization and accelerated intensification of multiple ranges of mobilization, a huge rise in precious fuel consumption and pollution was observed. Based on the recent hardships of fossil fuels, experts are undoubtedly eager in carrying out their research in renewable environment-friendly fuels. There have been many reviews of works considering the parameters and standards of biodiesel, which is only from various vegetable and seed oils. But very little review work was carried out on only plant-based biofuel. Plant-based fuel has a lower viscosity and higher volatility properties. The target of this review was to make a bridge to overcome these research gaps. This review extensively studies the biological background, production outcome, properties, and reliability of plant-based biofuel and also deeply investigates the feasibility of usage in a diesel engine. From deep investigation it was identified that most of the low viscous fuel had higher brake thermal efficiency (BTE) (2% to 4%) and NOx emission (5% to 10%) than high viscous biodiesel. The formation of hydrocarbon (HC), CO, and smoke emission was similar to high viscous biodiesel. Overall, the low viscous fuel effectively improves the engine behaviors.
  13. Fonte L, Lim BH, Sarmiento ME, Acosta A
    Front Immunol, 2023;14:1210743.
    PMID: 37215137 DOI: 10.3389/fimmu.2023.1210743
    MeSH terms: Animals; Helminthiasis*; Trichinellosis*; Trichinella spiralis*
  14. Jalaudin Basha NN, Adzuan Hafiz NB, Osman MS, Abu Bakar NF
    Front Toxicol, 2023;5:1135081.
    PMID: 37215383 DOI: 10.3389/ftox.2023.1135081
    Microplastic (MP) particles are considered noxious pollutants due to their presence in aquatic habitats at almost every level of the food chain. Thus, the entry of MP particles into marine waterbodies has triggered a common research interest. Until recently, the toxicity of polystyrene towards aquatic creatures in comparison to other polymers has not been widely investigated. This article provides an extensive overview of the occurrence of microplastic particles, the route of polystyrene (PS) in the aquatic ecosystem, the PS properties characterization, and its noxious effects on the aquatic biota, particularly fishes and microalgae. Alarming high levels of polystyrene were found in urban, coastal, and rural surface waters and sediments. The fast-screening technique began with a stereoscope to determine the polystyrene particles' shape, size, and color on the organism. SEM and complemented by micro FTIR or Raman spectroscopy were used to evaluate MP's polymer structures. The findings present evidence suggesting that polystyrene buildup in fish can have long-term and unknown consequences. Meanwhile, the presence of polystyrene on microalgae causes a decrease in chlorophyll concentration and photosynthetic activity, which may disrupt photosynthesis by interfering with the electron characters and leading to the production of reactive oxygen species (ROS).
  15. Ng YJ, Ling A, Nam LJ, Tylors PS, Bin Maliki AH, Wan Ali SA
    J Surg Case Rep, 2023 May;2023(5):rjad254.
    PMID: 37215624 DOI: 10.1093/jscr/rjad254
    Guillain Barre syndrome (GBS) as a complication of hyaluronic acid (HA) exposure is an extremely rare occurrence. We report a case of GBS, acute motor sensory axonal neuropathy (AMSAN) variant, after a HA breast enhancement procedure. A 41-year-old lady underwent a HA breast enhancement procedure from an unlicensed beautician and developed anaphylaxis followed by bilateral breast abscess and neurological deficits involving both motor and sensory components. The AMSAN variant of GBS was diagnosed from the cytoalbuminologic dissociation and nerve conduction study. Her GBS and breast abscess were managed with plasmapheresis and bilateral mastectomy. In this case, GBS was highly suspected to be caused by HA with possible impurities. To the author's knowledge, the association between HA and GBS has not been reported or known, and further studies are required to establish this association. To prevent mortality and morbidity, breast enhancement procedures should be performed by trained professionals with properly vetted products.
  16. Pt E, H Y, Y A, A A, J SN
    Heliyon, 2023 May;9(5):e15819.
    PMID: 37215784 DOI: 10.1016/j.heliyon.2023.e15819
    This study was aimed to assess internal and external factors related to youths' consumption behavior towards roasted chicken products. Qualitative interview was conducted with 30 selected respondents aged 15-20, 21-25 and 26 to 30 from a university and two high schools at Serdang, Selangor. An audio recorder was used to gather qualitative data over two months. A thematic content analysis was applied to identify the needed information, comprising of transcription, coding and theme development. Results disclosed that respondents in this study implied physiological attributes (delicious, tastiness, crispy texture, good flavour, brown colour, smoky aroma, own eating preference), personality attributes (availability, good hygiene, health concern), reference groups (friends, family members) and culture (family lifestyle, early life feeding behaviour) as significant factors that drive their purchase of roasted chicken products. This study's results also disclosed that the most prioritized factors were brown colour, health concern, friends and family lifestyle. The results of this study further identify physiological and personality attributes as internal factors, and reference groups and culture as external factors. Hence, this study concluded that internal factors (physiological, personality) and external factors (reference groups, culture) as essential factors in influencing youths' purchase of roasted chicken products. Thus, this study's outcome is beneficial for the vendors to boost their sales as well as promoting better ways of selecting foods to reduce the risk of non-communicable diseases amongst the youth in Malaysia.
  17. Abdullahi I, Hashim S, Sayyed MI, Ghoshal SK
    Heliyon, 2023 May;9(5):e15906.
    PMID: 37215796 DOI: 10.1016/j.heliyon.2023.e15906
    This paper reports an intense up-conversion luminescence from Dy3+-doped strontium-telluro-alumino-magnesium-borate glasses for the first time. The samples were made via the melt-quenching method and characterized to determine the influence of various CuO nanoparticles contents change on their up-conversion emission traits. Absorption spectral data were used to calculate the Judd-Ofelt intensity parameters. The sample without CuO nanoparticles revealed two intense photoluminescence up-conversion emission peaks at 478 and 570 nm. In addition, CuO nanoparticles-activated sample displayed about 1.4-fold up-conversion emission intensity improvement due to strong light absorption in the visible to the infrared region at 799 nm excitation. The stimulated emission cross-section of the CuO nanoparticles-activated glasses was increased from 102.4 × 10-23 to 1301.1 × 10-23 cm2 (nearly 10-fold amplification) while the branching ratio was reduced to 66.9%. Thus, CuO nanoparticles as an additive in the current glass matrix enhanced the up-conversion emission and strengthened the associated nonlinear optical properties. CIE 1931 color matching revealed the influence of CuO in modifying the up-conversion color coordinates, thereby improving the white color purity. The achieved up-conversion emission coupled with the color tunability of the proposed glasses may be advantageous for the up-conversion UV tunable laser making.
  18. Jamei E, Chau HW, Seyedmahmoudian M, Mekhilef SS, Sami FA
    Heliyon, 2023 May;9(5):e15917.
    PMID: 37215798 DOI: 10.1016/j.heliyon.2023.e15917
    In the past few decades, the air temperature of built environment and energy demand of buildings has been increased, particularly in summer. As a consequence, the number of heat waves, heat-related mortality and morbidity have increased. The wide application of air conditioning and high level of energy use are inevitable to save people's lives, particularly in hot and temperate climates. Under these circumstances, this study offers a scoping review of the articles published between 2000 and 2020 to evaluate the role of green roofs in building energy use in hot and temperate climates. Given the ongoing trend of urban overheating, the scope of this review is limited to hot-humid, temperate and hot-dry climate zones. This scoping review shows the benefits of green roofs for reducing the demand of building energy in different climate zones and highlights the higher magnitude of energy saving in temperate climates than hot-humid or hot-dry climates provided that the green roofs are well-irrigated and uninsulated. According to the review of the articles published between 2000 and 2020, the reduction in cooling load is maximum (mean 50.2%) in temperate climate zones for well-irrigated green roofs. The effectiveness in saving cooling load reduces in hot-humid and hot-dry climate zones with means of 10% and 14.8% respectively. Green roof's design elements also strongly influence the potential in saving energy, and the effectiveness is heavily influenced by background climatic conditions. The findings of this study assist building designers and communities to better understand the amount of energy savings due to green roofs and present the results in different climates quantitatively.
  19. Setyawati LU, Nurhidayah W, Khairul Ikram NK, Mohd Fuad WE, Muchtaridi M
    Heliyon, 2023 May;9(5):e16045.
    PMID: 37215800 DOI: 10.1016/j.heliyon.2023.e16045
    Alpha mangostin (AM), the main xanthone derivative contained in mangosteen pericarp (Garcinia mangostana/GM), has many pharmacological activities such as antioxidant, antiproliferation, antiinflammatory, and anticancer. Several general toxicity studies of AM have been previously reported to assess the safety profile of AM. Toxicity studies were carried out by various methods such as on test animals, interventions, and various routes of administration, but the test results have not been well documented. Our study aimed to systematically summarizes research on the safety profile of GM containing AM through general toxicity tests to get the LD50 and NOAEL values, and so, can be used as a database related to AM toxicity profiles. This could facilitate other researchers in determining further development of GM-or-AM-based products. Pubmed, Google scholar, ScienceDirect, and EBSCO were chosen to collect the articles while ARRIVE 2.0 was used to evaluate the quality and risk-of-bias of the in vivo toxicity studies included in this systematic review. A total of 20 articles met the eligibility criteria and were reviewed to predict the LD50 and NOAEL of AM. The results showed that the LD50 of AM is between >15.480 mg/kgBW to ≤6000 mg/kgBW while the NOAEL value is between <100 and ≤2000 mg/kgBW.
  20. Wang G, Alias SB, Sun Z, Wang F, Fan A, Hu H
    Heliyon, 2023 May;9(5):e16112.
    PMID: 37215850 DOI: 10.1016/j.heliyon.2023.e16112
    Influential nodes identification technology is one of the important topics which has been widely applied to logistics node location, social information dissemination, transportation network carrying, biological virus dissemination, power network anti-destruction, etc. At present, a large number of influential nodes identification methods have been studied, but the algorithms that are simple to execute, have high accuracy and can be better applied to real networks are still the focus of research. Therefore, due to the advantages of simple to execute in voting mechanism, a novel algorithm based on adaptive adjustment of voting ability (AAVA) to identify the influential nodes is presented by considering the local attributes of node and the voting contribution of its neighbor nodes, to solve the problem of low accuracy and discrimination of the existing algorithms. This proposed algorithm uses the similarity between the voting node and the voted node to dynamically adjust its voting ability without setting any parameters, so that a node can contribute different voting abilities to different neighbor nodes. To verify the performance of AAVA algorithm, the running results of 13 algorithms are analyzed and compared on 10 different networks with the SIR model as a reference. The experimental results show that the influential nodes identified by AAVA have high consistency with SIR model in Top-10 nodes and Kendall correlation, and have better infection effect of the network. Therefore, it is proved that AAV algorithm has high accuracy and effectiveness, and can be applied to real complex networks of different types and sizes.
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