Affiliations 

  • 1 School of Healthy Aging, Aesthetic and Regenerative Medicine, Faculty of Medicine and Health Sciences, UCSI University, 56000, Cheras, Kuala Lumpur, Malaysia
  • 2 Ikigai Medical Centre, Dubai Mall, Dubai, United Arab Emirates
  • 3 Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400, Serdang, Malaysia
  • 4 School of Healthy Aging, Aesthetic and Regenerative Medicine, Faculty of Medicine and Health Sciences, UCSI University, 56000, Cheras, Kuala Lumpur, Malaysia. cktan@ucsiuniversity.edu.my
Sci Rep, 2025 Jan 28;15(1):3507.
PMID: 39875543 DOI: 10.1038/s41598-025-87680-7

Abstract

Opuntia ficus-indica (OFi) is a major fruit source prevalent in semiarid and arid regions across various countries worldwide. It is widely recognised for its potential health benefits; however, most studies investigating its effects have been limited to pre-clinical models, highlighting the need for further validation through clinical trials. This study aimed to evaluate the effectiveness of OFi supplementation in enhancing antioxidant levels. Fifty healthy participants, aged 18 years and older, including males and females, received a daily OFi supplement of 1500 mg for 3 months. These findings revealed a significant 48.1% increase in salivary total antioxidant capacity (TAC) (P 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.