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2245G/A polymorphism of the receptor for advanced glycation end-products (RAGE) gene is associated with diabetic retinopathy in the Malaysian population

Ng ZX 1 , Kuppusamy UR , Tajunisah I , Fong KC , Koay AC , Chua KH

Affiliations 

  • 1 Department of Molecular Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia
Br J Ophthalmol, 2012 Feb;96(2):289-92.
PMID: 22116960 DOI: 10.1136/bjophthalmol-2011-300658

Abstract

The receptor for advanced glycation end-products (RAGE) has been implicated in the pathogenesis of diabetic microvascular complications. The aim of this study was to investigate the association between 2245G/A gene polymorphism of the RAGE gene and retinopathy in Malaysian type 2 diabetic patients.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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