Receptor for advanced glycation end-product (RAGE) gene polymorphism 2245G/A is associated with pro-inflammatory, oxidative-glycation markers and sRAGE in diabetic retinopathy

Ng ZX; Kuppusamy UR; Iqbal T; Chua KH

doi:10.1016/j.gene.2013.03.062

Receptor for advanced glycation end-product (RAGE) gene polymorphism 2245G/A is associated with pro-inflammatory, oxidative-glycation markers and sRAGE in diabetic retinopathy

Ng ZX ¹ , Kuppusamy UR , Iqbal T , Chua KH

Affiliations

¹ Department of Biomedical Science, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia

Gene, 2013 Jun 1;521(2):227-33.

PMID: 23545311 DOI: 10.1016/j.gene.2013.03.062

Abstract

Receptor for advanced glycation end-product (RAGE) gene polymorphism 2245G/A is associated with diabetic retinopathy (DR). However, the mechanism on how it affects the disease development is still unclear.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.