Affiliations 

  • 1 Department of BioMedical Engineering, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
Med J Malaysia, 2008 Jul;63 Suppl A:97.
PMID: 19025002

Abstract

Phenotypic variation in biofilm formation is common in clinical isolates of S. epidermidis. In the current study, nearly 5% of all clinical isolates analysed showed phenotypic variation in biofilm forming ability and electrophoretic mobility (EM). This is the first report of S. epidermidis strains irreversibly switching from biofilm-positive to biofilm-negative phenotype by spontaneous deletion of icaADBC genes which represents a new, possibly common mechanism of phenotypic variation.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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