Nucleosome levels and toll-like receptor expression during high cut-off haemofiltration: a pilot assessment

Atan R 1 , May C 2 , Bailey SR 3 , Tanudji M 4 , Visvanathan K 5 , Skinner N 6 Show all authors , Bellomo R 7 , Goehl H 8 , Storr M 9

Affiliations 

  • 1 Johor Bahru Clinical School, Monash University Malaysia, Johor, Malaysia. rinaldo.bellomo@austin.org.au
  • 2 Howard Florey Institute, Univerisity of Melbourne, Melbourne, VIC, Australia
  • 3 Faculty of Veterinary Science, University of Melbourne, Melbourne, VIC, Australia
  • 4 Sirtex Medical Ltd, Sydney, NSW, Australia
  • 5 Southern Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC, Australia
  • 6 St. Vincent's Hospital, University of Melbourne, Melbourne, VIC, Australia
  • 7 Australian and New Zealand Intensive Care Research Centre, Melbourne, VIC, Australia
  • 8 Department of Intensive Care, Austin Hospital, Melbourne, VIC, Australia
  • 9 Gambro Dialysatoren GmbH, Research and Development, Hechingen, Germany
Crit Care Resusc, 2015 Dec;17(4):239-43.
PMID: 26640058

Abstract

To measure plasma nucleosome levels and expression of toll-like receptors (TLRs) in a pilot cohort of patients with severe acute kidney injury (AKI) within a randomised controlled trial of continuous venovenous haemofiltration with high cut-off filters (CVVH-HCO) v standard filters (CVVH-std).

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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