Chemopreventive Effect of Phaleria macrocarpa on Colorectal Cancer Aberrant Crypt Foci In vivo

Shwter AN 1 , Abdullah NA 2 , Alshawsh MA 3 , El-Seedi HR 4 , Al-Henhena NA 5 , Khalifa SA 6 Show all authors , Abdulla MA 7

Affiliations 

  • 1 Department of Biomedical Science, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. Electronic address: abd_um@yahoo.com
  • 2 Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. Electronic address: noraziza@um.edu.my
  • 3 Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. Electronic address: alshaweshmam@um.edu.my
  • 4 Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia; Division of Pharmacognosy, Department of Medicinal Chemistry, Uppsala University, Box 574, SE-75 123, Uppsala, Sweden. Electronic address: hesham.el-seedi@fkog.uu.su
  • 5 Department of Biomedical Science, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. Electronic address: nalhenhena@yahoo.com
  • 6 Department of Experimental Hematology, Karolinska University Hospital, SE-141 86 Stockholm, Sweden. Electronic address: shaden.khalifa.2014@gmail.com
  • 7 Department of Biomedical Science, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. Electronic address: ammeen@um.edu.my
J Ethnopharmacol, 2016 Aug 1.
PMID: 27492327 DOI: 10.1016/j.jep.2016.08.002

Abstract

Natural products are important ingredients for pharmaceutical applications specifically new entities for treating cancer and other diseases. Phaleria macrocarpa is native of Indonesia and considered as a prolific source of bioactive substances useful for chemoprevention.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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