Incidence and management of cleft lip and palate in Pakistan

Sharif F 1 , Mahmood F 2 , Azhar MJ 3 , Asif A 1 , Zahid M 4 , Muhammad N 1 Show all authors , Rehman IU 5 , Neil SM 5

Affiliations 

  • 1 Interdisciplinary Research Centre in Biomedical Materials, COMSATS University Islamabad, Lahore Campus, Lahore, Pakistan
  • 2 Department of Plastic Surgery, Children Hospital, Lahore, Pakistan
  • 3 Department of Paediatrics, Avicenna Medical College, Lahore, Pakistan
  • 4 Department of Management and Humanities, Universiti Teknologi PETRONAS, Malaysia
  • 5 Department of Materials Science & Engineering, Kroto Research Institute, University of Sheffield, Sheffield, UK
J Pak Med Assoc, 2019 May;69(5):632-639.
PMID: 31105281

Abstract

OBJECTIVE: To compare the occurrence, distribution and management of clefts of lip and palate in local patients with the available data from India and China.

METHODS: The retrospective study was conducted at the Interdisciplinary Research Centre in Biomedical Materials, COMSATS University Islamabad, Lahore Campus, Lahore, Pakistan, and comprised data related to a three-month period from January to March 2015 at two medical centres in Lahore. Data from Pakistani centres was analysed based on province, gender, age and clefts of lip and palate conditions and Spearman's correlation matrix.

RESULTS: Of the 1574 cases, 1061(67.4%) were from Punjab, 361(23%) Khyber Pakhtunkhwa, 85(5%) Sindh and 67(4.2%) were from Azad Jammu and Kashmir. The incidence of clefts of lip and palate was higher in males than females. There was higher awareness of the need for timely management in new borns with clefts of lip and palate. Some patients seeking secondary treatment were also being surgically corrected. There is no national registry of children born with cleft defect, making it difficult to assess the full scale of the problem..

CONCLUSIONS: Based on available data, it is likely that there are many adults who have not been treated when younger..

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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