Affiliations 

  • 1 Department of Paediatrics, University Malaya Medical Centre, Kuala Lumpur, Malaysia. Electronic address: kschew@ummc.edu.my
  • 2 Department of Paediatrics, University Malaya Medical Centre, Kuala Lumpur, Malaysia
  • 3 Department of Paediatrics, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia
  • 4 Department of Paediatrics, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia; University Malaya Paediatrics and Child Health Research Group, University Malaya, Kuala Lumpur, Malaysia
Pediatr Neonatol, 2021 01;62(1):49-54.
PMID: 32891528 DOI: 10.1016/j.pedneo.2020.08.009

Abstract

BACKGROUND: Functional gastrointestinal disorders (FGIDs) are common in children. The prevalence of FGIDs varies across the world but is unknown in Malaysia. We aimed to investigate the prevalence of FGIDs in healthy Malaysian infants.

METHODS: This was a cross-sectional study involving healthy infants younger than 12 months of age who attended a well-baby clinic. A universal sampling method was adopted. Children with congenital disorders potentially affecting gastrointestinal functions, chronic debilitating diseases and hypothyroidism were excluded. Rome IV criteria were used to define FGIDs.

RESULTS: Of the total 534 infants recruited (54% males), 92% were born at term; 85% had normal birth weight [range 2.5-4.0 kg], and the mean (±S.D.) age at interview was 6.8 (±3.4) months. Thirty-six percent were breastfed, 29% were formula-fed, and 35% had mixed feeding. Prevalence of infant regurgitation and rumination syndrome was 10.5% and 1.7%, respectively. Prevalence of infant colic was 1.9% (3/160) (infant 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.