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Fulltext Unsupervised bivariate data clustering for damage assessment of carbon fiber composite laminates

May Z, Alam MK, Mahmud MS, Rahman NAA

PLoS One, 2020;15(11):e0242022.
PMID: 33186372 DOI: 10.1371/journal.pone.0242022

Damage assessment is a key element in structural health monitoring of various industrial applications to understand well and predict the response of the material. The big uncertainty in carbon fiber composite materials response is because of variability in the initiation and propagation of damage. Developing advanced tools to design with composite materials, methods for characterizing several damage modes during operation are required. While there is a significant amount of work on the analysis of acoustic emission (AE) from different composite materials and many loading cases, this research focuses on applying an unsupervised clustering method for separating AE data into several groups with distinct evolution. In this paper, we develop an adaptive sampling and unsupervised bivariate data clustering techniques to characterize the several damage initiations of a composite structure in different lay-ups. An adaptive sampling technique pre-processes the AE features and eliminates redundant AE data samples. The reduction of unnecessary AE data depends on the requirements of the proposed bivariate data clustering technique. The bivariate data clustering technique groups the AE data (dependent variable) with respect to the mechanical data (independent variable) to assess the damage of the composite structure. Tensile experiments on carbon fiber reinforced composite laminates (CFRP) in different orientations are carried out to collect mechanical and AE data and demonstrate the damage modes. Based on the mechanical stress-strain data, the results show the dominant damage regions in different lay-ups of specimens and the definition of the different states of damage. In addition, the states of the damage are observed using Scanning Electron Microscope (SEM) analysis. Based on the AE data, the results show that the strong linear correlation between AE and mechanical energy, and the classification of various modes of damage in all lay-ups of specimens forming clusters of AE energy with respect to the mechanical energy. Furthermore, the validation of the cluster-based characterization and improvement of the sensitivity of the damage modes classification are observed by the combined knowledge of AE and mechanical energy and time-frequency spectrum analysis.

Matched MeSH terms: Materials Testing/methods
Transmission of vibration through glove materials: effects of contact force

Md Rezali KA, Griffin MJ

Ergonomics, 2018 Sep;61(9):1246-1258.
PMID: 29628001 DOI: 10.1080/00140139.2018.1462407

This study investigated effects of applied force on the apparent mass of the hand, the dynamic stiffness of glove materials and the transmission of vibration through gloves to the hand. For 10 subjects, 3 glove materials and 3 contact forces, apparent masses and glove transmissibilities were measured at the palm and at a finger at frequencies in the range 5-300 Hz. The dynamic stiffnesses of the materials were also measured. With increasing force, the dynamic stiffnesses of the materials increased, the apparent mass at the palm increased at frequencies greater than the resonance and the apparent mass at the finger increased at low frequencies. The effects of force on transmissibilities therefore differed between materials and depended on vibration frequency, but changes in apparent mass and dynamic stiffness had predictable effects on material transmissibility. Depending on the glove material, the transmission of vibration through a glove can be increased or decreased when increasing the applied force. Practitioner summary: Increasing the contact force (i.e. push force or grip force) can increase or decrease the transmission of vibration through a glove. The vibration transmissibilities of gloves should be assessed with a range of contact forces to understand their likely influence on the exposure of the hand and fingers to vibration.

Matched MeSH terms: Materials Testing/methods
Fulltext Thermal behavior of cylindrical buckling restrained braces at elevated temperatures

Talebi E, Tahir MM, Zahmatkesh F, Yasreen A, Mirza J

ScientificWorldJournal, 2014;2014:672629.
PMID: 24526915 DOI: 10.1155/2014/672629

The primary focus of this investigation was to analyze sequentially coupled nonlinear thermal stress, using a three-dimensional model. It was meant to shed light on the behavior of Buckling Restraint Brace (BRB) elements with circular cross section, at elevated temperature. Such bracing systems were comprised of a cylindrical steel core encased in a strong concrete-filled steel hollow casing. A debonding agent was rubbed on the core's surface to avoid shear stress transition to the restraining system. The numerical model was verified by the analytical solutions developed by the other researchers. Performance of BRB system under seismic loading at ambient temperature has been well documented. However, its performance in case of fire has yet to be explored. This study showed that the failure of brace may be attributed to material strength reduction and high compressive forces, both due to temperature rise. Furthermore, limiting temperatures in the linear behavior of steel casing and concrete in BRB element for both numerical and analytical simulations were about 196°C and 225°C, respectively. Finally it is concluded that the performance of BRB at elevated temperatures was the same as that seen at room temperature; that is, the steel core yields prior to the restraining system.

Matched MeSH terms: Materials Testing/methods*
Fulltext Strength development of high-strength ductile concrete incorporating Metakaolin and PVA fibers

Nuruddin MF, Khan SU, Shafiq N, Ayub T

ScientificWorldJournal, 2014;2014:387259.
PMID: 24707202 DOI: 10.1155/2014/387259

The mechanical properties of high-strength ductile concrete (HSDC) have been investigated using Metakaolin (MK) as the cement replacing material and PVA fibers. Total twenty-seven (27) mixes of concrete have been examined with varying content of MK and PVA fibers. It has been found that the coarser type PVA fibers provide strengths competitive to control or higher than control. Concrete with coarser type PVA fibers has also refined microstructure, but the microstructure has been undergone with the increase in aspect ratio of fibers. The microstructure of concrete with MK has also more refined and packing of material is much better with MK. PVA fibers not only give higher stiffness but also showed the deflection hardening response. Toughness Index of HSDC reflects the improvement in flexural toughness over the plain concrete and the maximum toughness indices have been observed with 10% MK and 2% volume fraction of PVA fibers.

Matched MeSH terms: Materials Testing/methods*
Sterilisation effect study on granular hydroxyapatite (HA)

Saidu MF, Mashita M, Khadijah K, Fazan F, Khalid KA

Med J Malaysia, 2004 May;59 Suppl B:85-6.
PMID: 15468831

Hydroxyapatite is a calcium phosphate bioceramic that has been shown by many authors to be biocompatible with bioactive properties. It is widely accepted as the best synthetic material available for surgical use as a bone graft substitute. HA granules produced by AMREC-SIRIM from local materials underwent 5 types of sterilisation techniques with different ageing periods. Samples were tested for chemical and phase composition and microbial contamination before and after being sterilised. From the microbiological tests done, none of the unsterilised positive control yielded a positive culture. Results from X-Ray diffraction studies found that all the sterilisation techniques did not chemically degrade or structurally change the HA granules significantly.

Matched MeSH terms: Materials Testing/methods*
Some flexural properties of a nylon denture base polymer

Yunus N, Rashid AA, Azmi LL, Abu-Hassan MI

J Oral Rehabil, 2005 Jan;32(1):65-71.
PMID: 15634304

Nylon denture base material could be a useful alternative to poly (methyl methacrylate) (PMMA) in special circumstances such as patient allergy to the monomer. The aim of this study was to evaluate the flexural properties of a nylon denture base material (Lucitone FRS), a conventional compression-moulded heat-polymerized (Meliodent), a compression-moulded microwave-polymerized (Acron MC) and an injection-moulded microwave-polymerized (Lucitone 199) PMMA polymers. The effect of aldehyde-free, oxygen releasing disinfectant solution (Perform) on these properties was also investigated. The flexural modulus and the flexural strength were assessed with a three-point bending test. Specimens were stored in water at a temperature of 37 degrees C for 30 days. For each material, half of the prepared specimens were randomly selected and immersed in the disinfectant 24 h prior to testing. Results were compared statistically at a confidence level of 95%. The result showed that in both the control and disinfected groups, the flexural modulus of nylon was significantly lower than the three PMMA polymers. The flexural strength of nylon was significantly lower than those of Meliodent and Acron MC but was comparable with Lucitone 199. A 24-h immersion in the disinfecting solution increased the rigidity of nylon denture base material.

Matched MeSH terms: Materials Testing/methods
Fulltext Reducing local scouring at bridge piles using collars and geobags

Akib S, Liana Mamat N, Basser H, Jahangirzadeh A

ScientificWorldJournal, 2014;2014:128635.
PMID: 25247201 DOI: 10.1155/2014/128635

The present study examines the use of collars and geobags for reducing local scour around bridge piles. The efficiency of collars and geobags was studied experimentally. The data from the experiments were compared with data from earlier studies on the use of single piles with a collar and with a geobag. The results showed that using a combination of a steel collar and a geobag yields the most significant scour reduction for the front and rear piles, respectively. Moreover, the independent steel collar showed better efficiency than the independent geobag below the sediment level around the bridge piles.

Matched MeSH terms: Materials Testing/methods
Rate adaptive pacing in an intracardiac pacemaker

Lloyd M, Reynolds D, Sheldon T, Stromberg K, Hudnall JH, Demmer WM, et al.

Heart Rhythm, 2017 02;14(2):200-205.
PMID: 27871854 DOI: 10.1016/j.hrthm.2016.11.016

BACKGROUND: The Micra transcatheter pacemaker was designed to have similar functionality to conventional transvenous VVIR pacing systems. It provides rate adaptive pacing using a programmable 3-axis accelerometer designed to detect patient activity in the presence of cardiac motion.
OBJECTIVE: The purpose of this study was to evaluate the system's performance during treadmill tests to maximum exertion in a subset of patients within the Micra Transcatheter Pacing Study.
METHODS: Patients underwent treadmill testing at 3 or 6 months postimplant with algorithm programming at physician discretion. Normalized sensor rate (SenR) relative to the programmed upper sensor rate was modeled as a function of normalized workload in metabolic equivalents (METS) relative to maximum METS achieved during the test. A normalized METS and SenR were determined at the end of each 1-minute treadmill stage. The proportionality of SenR to workload was evaluated by comparing the slope from this relationship to the prospectively defined tolerance margin (0.65-1.35).
RESULTS: A total of 69 treadmill tests were attempted by 42 patients at 3 and 6 months postimplant. Thirty tests from 20 patients who completed ≥4 stages with an average slope of 0.86 (90% confidence interval 0.77-0.96) confirmed proportionality to workload. On an individual test basis, 25 of 30 point estimates (83.3%) had a normalized slope within the defined tolerance range (range 0.46-1.08).
CONCLUSION: Accelerometer-based rate adaptive pacing was proportional to workload, thus confirming rate adaptive pacing commensurate to workload is achievable with an entirely intracardiac pacing system.

Matched MeSH terms: Materials Testing/methods
Process of prototyping coronary stents from biodegradable Fe-Mn alloys

Hermawan H, Mantovani D

Acta Biomater, 2013 Nov;9(10):8585-92.
PMID: 23665503 DOI: 10.1016/j.actbio.2013.04.027

Biodegradable stents are considered to be a recent innovation, and their feasibility and applicability have been proven in recent years. Research in this area has focused on materials development and biological studies, rather than on how to transform the developed biodegradable materials into the stent itself. Currently available stent technology, the laser cutting-based process, might be adapted to fabricate biodegradable stents. In this work, the fabrication, characterization and testing of biodegradable Fe-Mn stents are described. A standard process for fabricating and testing stainless steel 316L stents was referred to. The influence of process parameters on the physical, metallurgical and mechanical properties of the stents, and the quality of the produced stents, were investigated. It was found that some steps of the standard process such as laser cutting can be directly applied, but changes to parameters are needed for annealing, and alternatives are needed to replace electropolishing.

Matched MeSH terms: Materials Testing/methods*
Polyelectrolyte multi-layers assembly of SiCHA nanopowders and collagen type I on aminolysed PLA films to enhance cell-material interactions

Baba Ismail YM, Ferreira AM, Bretcanu O, Dalgarno K, El Haj AJ

Colloids Surf B Biointerfaces, 2017 Nov 01;159:445-453.
PMID: 28837894 DOI: 10.1016/j.colsurfb.2017.07.086

This paper presents a new approach in assembling bone extracellular matrix components onto PLA films, and investigates the most favourable environment which can be created using the technique for cell-material interactions. Poly (lactic acid) (PLA) films were chemically modified by covalently binding the poly(ethylene imine) (PEI) as to prepare the substrate for immobilization of polyelectrolyte multilayers (PEMs) coating. Negatively charged polyelectrolyte consists of well-dispersed silicon-carbonated hydroxyapatite (SiCHA) nanopowders in hyaluronic acid (Hya) was deposited onto the modified PLA films followed by SiCHA in collagen type I as the positively charged polyelectrolyte. The outermost layer was finally cross-linked by 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrocholoride and N-hydroxysulfosuccinimide sodium salt (EDC/NHS) solutions. The physicochemical features of the coated PLA films were monitored via X-ray Photoelectron Spectroscopy (XPS) and Atomic Force Microscope (AFM). The amounts of calcium and collagen deposited on the surface were qualitatively and quantitatively determined. The surface characterizations suggested that 5-BL has the optimum surface roughness and highest amounts of calcium and collagen depositions among tested films. In vitro human mesenchymal stem cells (hMSCs) cultured on the coated PLA films confirmed that the coating materials greatly improved cell attachment and survival compared to unmodified PLA films. The cell viability, cell proliferation and Alkaline Phosphatase (ALP) expression on 5-BL were found to be the most favourable of the tested films. Hence, this newly developed coating materials assembly could contribute to the improvement of the bioactivity of polymeric materials and structures aimed to bone tissue engineering applications.

Matched MeSH terms: Materials Testing/methods*
Fulltext Partial discharge characteristics of polymer nanocomposite materials in electrical insulation: a review of sample preparation techniques, analysis methods, potential applications, and future trends

Izzati WA, Arief YZ, Adzis Z, Shafanizam M

ScientificWorldJournal, 2014;2014:735070.
PMID: 24558326 DOI: 10.1155/2014/735070

Polymer nanocomposites have recently been attracting attention among researchers in electrical insulating applications from energy storage to power delivery. However, partial discharge has always been a predecessor to major faults and problems in this field. In addition, there is a lot more to explore, as neither the partial discharge characteristic in nanocomposites nor their electrical properties are clearly understood. By adding a small amount of weight percentage (wt%) of nanofillers, the physical, mechanical, and electrical properties of polymers can be greatly enhanced. For instance, nanofillers in nanocomposites such as silica (SiO2), alumina (Al2O3) and titania (TiO2) play a big role in providing a good approach to increasing the dielectric breakdown strength and partial discharge resistance of nanocomposites. Such polymer nanocomposites will be reviewed thoroughly in this paper, with the different experimental and analytical techniques used in previous studies. This paper also provides an academic review about partial discharge in polymer nanocomposites used as electrical insulating material from previous research, covering aspects of preparation, characteristics of the nanocomposite based on experimental works, application in power systems, methods and techniques of experiment and analysis, and future trends.

Matched MeSH terms: Materials Testing/methods*
New bioactive glass-ceramic: synthesis and application in PMMA bone cement composites

Abd Samad H, Jaafar M, Othman R, Kawashita M, Abdul Razak NH

Biomed Mater Eng, 2011;21(4):247-58.
PMID: 22182792 DOI: 10.3233/BME-2011-0673

In present study, a new composition of glass-ceramic was synthesized based on the Na2O-CaO-SiO2-P2O5 glass system. Heat treatment of glass powder was carried out in 2 stages: 600 °C as the nucleation temperature and different temperature on crystallization at 850, 950 and 1000 °C. The glass-ceramic heat-treated at 950 °C was selected as bioactive filler in commercial PMMA bone cement; (PALACOS® LV) due to its ability to form 2 high crystallization phases in comparison with 850 and 1000 °C. The results of this newly glass-ceramic filled PMMA bone cement at 0-16 wt% of filler loading were compared with those of hydroxyapatite (HA). The effect of different filler loading on the setting properties was evaluated. The peak temperature during the polymerization of bone cement decreased when the liquid to powder (L/P) ratio was reduced. The setting time, however, did not show any trend when filler loading was increased. In contrast, dough time was observed to decrease with increased filler loading. Apatite morphology was observed on the surface of the glass-ceramic and selected cement after bioactivity test.

Matched MeSH terms: Materials Testing/methods
Medicinal and cosmetics soap production from Jatropha oil

Shahinuzzaman M, Yaakob Z, Moniruzzaman M

J Cosmet Dermatol, 2016 Jun;15(2):185-93.
PMID: 26777540 DOI: 10.1111/jocd.12209

Soap is the most useful things which we use our everyday life in various cleansing and cosmetics purposes. Jatropha oil is nonedible oil which has more benefits to soap making. It has also cosmetics and medicinal properties. But the presence of toxic Phorbol esters in Jatropha oil is the main constrains to use it. So it is necessary to search a more suitable method for detoxifying the Jatropha oil before the use as the main ingredient of soap production. This review implies a more suitable method for removing phorbol esters from Jatropha oil. Several parameters such as the % yield of pure Jatropha oil soap, TFM value of soap, total alkali content, free caustic alkalinity content, pH, the antimicrobial activity, and CMC value of general soap should be taken into consideration for soap from detoxified Jatropha oil.

Matched MeSH terms: Materials Testing/methods
Fulltext Measurements of the stiffness and thickness of the pavement asphalt layer using the enhanced resonance search method

Zakaria NM, Yusoff NI, Hardwiyono S, Nayan KA, El-Shafie A

ScientificWorldJournal, 2014;2014:594797.
PMID: 25276854 DOI: 10.1155/2014/594797

Enhanced resonance search (ERS) is a nondestructive testing method that has been created to evaluate the quality of a pavement by means of a special instrument called the pavement integrity scanner (PiScanner). This technique can be used to assess the thickness of the road pavement structure and the profile of shear wave velocity by using the principle of surface wave and body wave propagation. In this study, the ERS technique was used to determine the actual thickness of the asphaltic pavement surface layer, while the shear wave velocities obtained were used to determine its dynamic elastic modulus. A total of fifteen locations were identified and the results were then compared with the specifications of the Malaysian PWD, MDD UKM, and IKRAM. It was found that the value of the elastic modulus of materials is between 3929 MPa and 17726 MPa. A comparison of the average thickness of the samples with the design thickness of MDD UKM showed a difference of 20 to 60%. Thickness of the asphalt surface layer followed the specifications of Malaysian PWD and MDD UKM, while some of the values of stiffness obtained are higher than the standard.

Matched MeSH terms: Materials Testing/methods
JectOS® versus PMMA vancomycin-loaded cement: The biomechanical and antimicrobial properties

Singh VA, Wei CC, Haseeb A, Shanmugam R, Ju CS

J Orthop Surg (Hong Kong), 2019 2 26;27(1):2309499018822247.
PMID: 30798727 DOI: 10.1177/2309499018822247

PURPOSE: Bone cement is commonly used as a void filler for bone defects. Antibiotics can be added to bone cement to increase local drug delivery in eradicating infection. After antibiotic elution, nonbiodegradable material becomes an undesirable agent. The purpose of this study was to evaluate effects of addition of vancomycin on the compressive strength of injectable synthetic bone substitute, JectOS®. JectOS, a partially biodegradable cement that over time dissolves and is replaced by bone, could be potentially used as a biodegradable antibiotic carrier.
METHODS: Vancomycin at various concentrations was added to JectOS and polymethyl methacrylate (PMMA). Then, the cement was molded into standardized dimensions for in vitro testing. Cylindrical vancomycin-JectOS samples were subjected to compressive strength. The results obtained were compared to PMMA-vancomycin compressive strength data attained from historical controls. The zone of inhibition was carried out using vancomycin-JectOS and vancomycin-PMMA disk on methicillin-resistant strain culture agar.
RESULTS: With the addition of 2.5%, 5%, and 10% vancomycin, the average compressive strengths reduced to 8.01 ± 0.95 MPa (24.6%), 7.52 ± 0.71 MPa (29.2%), and 7.23 ± 1.34 MPa (31.9%). Addition of vancomycin significantly weakened biomechanical properties of JectOS, but there was no significant difference in the compressive strength at increasing concentrations. The average diameters of zone of inhibition for JectOS-vancomycin were 24.7 ± 1.44 (2.5%) mm, 25.9 ± 0.85 mm (5%), and 26.8 ± 1.81 mm (10%), which outperformed PMMA.
CONCLUSION: JectOS has poor mechanical performance but superior elution property. JectOS-vancomycin cement is suitable as a void filler delivering high local concentration of vancomycin. We recommended using it for contained bone defects that do not require mechanical strength.

Matched MeSH terms: Materials Testing/methods*
Investigation into mechanical, absorption and swelling behaviour of hemp/sisal fibre reinforced bioepoxy hybrid composites: Effects of stacking sequences

Thiagamani SMK, Krishnasamy S, Muthukumar C, Tengsuthiwat J, Nagarajan R, Siengchin S, et al.

Int J Biol Macromol, 2019 Nov 01;140:637-646.
PMID: 31437507 DOI: 10.1016/j.ijbiomac.2019.08.166

This work focuses on the fabrication of hybrid bio-composites using green epoxy as the matrix material, hemp (H) and sisal (S) fibre mats as the reinforcements. The hybrid composite with sisal/hemp fibres were fabricated by cost effective hand lay-up technique, followed by hot press with different stacking sequences. Static properties of the composites such as tensile, compressive, inter-laminar shear strengths (ILSS) and hardness were examined. The physical properties such as density, void content, water absorption and thickness swelling were also analyzed. The experimental results indicate that hybrid composites exhibited minor variation in tensile strength when the stacking sequence was altered. The hybrid composite with the intercalated arrangement (HSHS) exhibited the highest tensile modulus when compared with the other hybrid counterparts. Hybrid composites (SHHS and HSSH) offered 40% higher values of compressive strength than the other layering arrangements. HHHH sample exhibited the highest ILSS value of 4.08 MPa. Typical failure characteristics of the short beam test such as inter-laminar shear cracks in the transverse direction, micro-buckling and fibre rupture were also observed.

Matched MeSH terms: Materials Testing/methods
Fulltext Improving rutting resistance of pavement structures using geosynthetics: an overview

Mirzapour Mounes S, Karim MR, Khodaii A, Almasi MH

ScientificWorldJournal, 2014;2014:764218.
PMID: 24526919 DOI: 10.1155/2014/764218

A pavement structure consists of several layers for the primary purpose of transmitting and distributing traffic loads to the subgrade. Rutting is one form of pavement distresses that may influence the performance of road pavements. Geosynthetics is one type of synthetic materials utilized for improving the performance of pavements against rutting. Various studies have been conducted on using different geosynthetic materials in pavement structures by different researchers. One of the practices is a reinforcing material in asphalt pavements. This paper intends to present and discuss the discoveries from some of the studies on utilizing geosynthetics in flexible pavements as reinforcement against permanent deformation (rutting).

Matched MeSH terms: Materials Testing/methods*
Fulltext Evaluation of new suspension system for limb prosthetics

Gholizadeh H, Abu Osman NA, Eshraghi A, Ali S, Arifin N, Wan Abas WA

Biomed Eng Online, 2014;13:1.
PMID: 24410918 DOI: 10.1186/1475-925X-13-1

Good prosthetic suspension system secures the residual limb inside the prosthetic socket and enables easy donning and doffing. This study aimed to introduce, evaluate and compare a newly designed prosthetic suspension system (HOLO) with the current suspension systems (suction, pin/lock and magnetic systems).

Matched MeSH terms: Materials Testing/methods*
Fulltext Engineering electrospun multicomponent polyurethane scaffolding platform comprising grapeseed oil and honey/propolis for bone tissue regeneration

Chao CY, Mani MP, Jaganathan SK

PLoS One, 2018;13(10):e0205699.
PMID: 30372449 DOI: 10.1371/journal.pone.0205699

Essential oils play an important role in reducing the pain and inflammation caused by bone fracture.In this study, a scaffold was electrospun based on polyurethane (PU), grape seed oil, honey and propolis for bone tissue-engineering applications. The fiber diameter of the electrospun PU/grape seed oil scaffold and PU/grape seed oil/honey/propolis scaffold were observed to be reduced compared to the pristine PU control. FTIR analysis revealed the existence of grape seed oil, honey and propolis in PU identified by CH band peak shift and also hydrogen bond formation. The contact angle of PU/grape seed oil scaffold was found to increase owing to hydrophobic nature and the contact angle for the PU/grape seed/honey oil/propolis scaffold were decreased because of hydrophilic nature. Further, the prepared PU/grape seed oil and PU/grape seed oil/honey/propolis scaffold showed enhanced thermal stability and reduction in surface roughness than the control as revealed in thermogravimetric analysis (TGA) and atomic force microscopy (AFM) analysis. Further, the developed nanocomposite scaffold displayed delayed blood clotting time than the pristine PU in the activated prothrombin time (APTT) and partial thromboplastin time (PT) assay. The hemolytic assay and cytocompatibility studies revealed that the electrospun PU/grape seed oil and PU/grape seed oil/honey/propolis scaffold possess non-toxic behaviour to red blood cells (RBC) and human fibroblast cells (HDF) cells indicating better blood compatibility and cell viability rates. Hence, the newly developed electrospun nanofibrous composite scaffold with desirable characteristics might be used as an alternative candidate for bone tissue engineering applications.

Matched MeSH terms: Materials Testing/methods
Fulltext Electrospun novel nanocomposite comprising polyurethane integrated with ayurveda amla oil for bone tissue engineering

Jaganathan SK, Mani MP

An Acad Bras Cienc, 2020;92(1):e20180369.
PMID: 32236296 DOI: 10.1590/0001-3765202020180369

Ayurveda oil contains numerous source of biological constituents which plays an important role in reducing the pain relief caused during bone fracture. The aim of the study is to fabricate the polyurethane (PU) scaffold for bone tissue engineering added with ayurveda amla oil using electrospinning technique. Scanning Electron Microscopy (SEM) analysis showed that the fabricated nanocomposites showed reduced fiber diameter (758 ± 185.46 nm) than the pristine PU (890 ± 116.91 nm). Fourier Infrared Analysis (FTIR) revealed the existence of amla oil in the PU matrix by hydrogen bond formation. The contact angle results revealed the decreased wettability (116° ± 1.528) of the prepared nanocomposites compared to the pure PU (100° ± 0.5774). The incorporation of amla oil into the PU matrix improved the surface roughness. Further, the coagulation assay indicated that the addition of amla oil into PU delayed the blood clotting times and exhibited less toxic to red blood cells. Hence, the fabricated nanocomposites showed enhanced physicochemical and better blood compatibility parameters which may serve as a potential candidate for bone tissue engineering.

Matched MeSH terms: Materials Testing/methods*

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