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  1. Graft and Button Modification of Technique of Coracoclavicular Joint Reconstruction in Treatment of Chronic Type V Acromioclavicular Joint Dislocation: A Case Report
    Leong YC, Muhammad-Suhairi J
    Malays Orthop J, 2019 Jul;13(2):45-48.
    PMID: 31467652 DOI: 10.5704/MOJ.1907.009
    Treatment of chronic Rockwood's type V Acromioclavicular (AC) joint dislocation remains controversial. We describe a surgical technique to reduce and maintain AC joint using a combination of gracilis autograft with GraftMax™ button (Conmed Inc, Utica, NY). Graft was prepared using running whip stitch technique with No. 5 Hi-Fi high strength suture (ConMed Linvatec, Largo, FL). Our technique reduces intraoperative clavicular and coracoid tunnel fracture and restores anatomical coracoclavicular ligament. At sixth week and third month postoperatively, the patient demonstrated good clinical and radiographic outcome.
    Matched MeSH terms: Humans
  2. A Single Posterolateral Scapular Approach to Drain Post-Traumatic Intramuscular Scapular and Axillary Abscess in an Adolescent: A Case Report
    Khaw YC, Faisham WI
    Malays Orthop J, 2019 Jul;13(2):56-58.
    PMID: 31467655 DOI: 10.5704/MOJ.1907.012
    Scapular abscess is a rare clinical diagnosis. This is a report of an atypical case of extensive intramuscular scapular abscess involving the anterior and posterior aspects of the scapula with extension into the axillary region following minor trauma in a young healthy adolescent, describing a single posterolateral approach to the scapula to evacuate the abscess. Following surgical drainage and antibiotic treatment, patient recovered without any complication.
    Matched MeSH terms: Humans
  3. METOPROLOL SUCCINATE: GENETIC ASPECTS OF INDIVIDUAL SENSITIVITY AND EFFICACY IN PATIENTS WITH OBESITY AND CHRONIC HEART FAILURE
    Gasanov I, Rudyk Y
    Georgian Med News, 2019 Jan.
    PMID: 30829590
    Aim - optimization of the treatment of obesity and chronic heart failure (CHF) patients by identifying key factors for the progression of cardiac decompensation and the principles of using metoprolol succinate, taking into account pharmacogenetic aspects in the complex treatment of this comorbidity. 127 patients with CHF 2nd-3rd stages, 1st-4th functional class by New York Heart Association at the age of 32-87 (61 [57; 65]) years were examined, including 93 men and 34 women. A comparative analysis of certain clinical criteria using the sequential analysis of Wald A.A. The results were statistically plausible with p<0.05. Conducting factor analysis allowed to separate groups of indicators and estimate the specific weight of individual factors in the pathogenesis of combined pathology - obesity and heart failure. The first two factors determine 76.8% of the variability of the indicators, given the indicators that load them, they were given descriptive titles "clinical-hemodynamic factor", "clinical and anthropometric factor". The proposed prognostic protocol provides new possibilities for predicting the efficacy of metoprolol succinate in patients with obesity and chronic heart failure. The developed discriminatory models allow to objectify the criteria for determining the doses of metoprolol succinate in patients with obesity and chronic heart failure - the maximum initial, maximal endpoint, and also to evaluate the expediency of a subsequent stepwise increase in dose. Perspective of further studies - development and clinical approbation of the protocol of the use of metoprolol succinate in patients with CHF in the context of obesity, taking into account the results of the conducted factor analysis and developed prognostic means.
    Matched MeSH terms: Humans
  4. Integrative biomarkers of biologic aging in HIV
    Rajasuriar R, Palmer C, Abdel-Mohsen M, Kamaruzzaman SB
    AIDS, 2019 02 01;33(2):345-347.
    PMID: 30562173 DOI: 10.1097/QAD.0000000000002064
    Matched MeSH terms: Humans
  5. Synergistic effects of VE-TPGS and riboflavin in crosslinking of dentine
    Daood U, Matinlinna JP, Fawzy AS
    Dent Mater, 2019 02;35(2):356-367.
    PMID: 30528297 DOI: 10.1016/j.dental.2018.11.031
    OBJECTIVE: Effect of d-alpha-tocopheryl poly(ethyleneglycol)-1000-succinate (VE-TPGS) with riboflavin-5'-phosphate solution on crosslinking of dentine collagen was investigated to analyze collagen's structural integrity.

    METHODS: VE-TPGS was added to RF-solution, at RF/VE-TPGS (w/w) ratios of 0.125/0.250 and 0.125/0.500. Demineralized dentine beams were used (10wt.% phosphoric acid), rinsed using deionized-water and analysed using ELISA (Human MMP2 ELISA; Human CTSK/Cathepsin-K for MMP2 and Cathepsin K analysis). AFM of dentine collagen-fibrils structure was done before and after dentine specimens' placement in mineralization solution and tested after 14days in artificial saliva/collagenase (AS/Co) solution. The specimens were tested after 24h in mineralization solution for surface/bulk elastic modulus. Nano-indentation was carried out for each specimen on intertubular-dentine with lateral spacing of 400nm. Reduced elastic-modulus and nano-hardness were calculated and collagen content was determined using hydroxyproline-assay. Micro-Raman were performed. TEM was carried out to study structural variations of dentine-collagen in artificial-saliva (collagenase). Data were presented as mean±standard deviation and analyzed by SPSS v.15, by analysis of variance.

    RESULTS: Synergetic effect of VE-TPGS was observed with RF through higher structural integrity of dentine collagen-fibrils shown by TEM/AFM. Superior surface/bulk mechanical stability was shown by nano-indentation/mechanical testing. Improvement in collagenase degradation resistance for hydroxyproline release was observed and lower endogenous-protease release of MMP-2/Cathepsin-K. Raman-analysis analysed chemical interactions between RF and collagen confirming structural-integrity of collagen fibrils after crosslinking. After 24h mineralization, AFM showed mineral depositions in close association with dentine-collagen fibrils with RF/VE-TPGS formulations.

    SIGNIFICANCE: Potential synergetic effect of RF/VE-TPGS was observed by reflection of higher structural integrity and conformational-stability of dentine-collagen fibrils.

    Matched MeSH terms: Humans
  6. Fulltext Experimental Breast Phantom Imaging with Metamaterial-Inspired Nine-Antenna Sensor Array
    Islam MT, Samsuzzaman M, Islam MT, Kibria S
    Sensors (Basel), 2018 Dec 14;18(12).
    PMID: 30558191 DOI: 10.3390/s18124427
    An experimental system for early screening of a breast tumor is presented in this article. The proposed microwave imaging (MI) system consists of a moveable array of nine improved negative-index metamaterial (MTM)-loaded ultrawideband (UWB) antenna sensor with incorporation of a corresponding SRR (split-ring resonator) and CLS (capacitively loaded strip) structure, in a circular array, the stepper motor-based array-mounting stand, the adjustable phantom hanging platform, an RF switching system to control the receivers, and a personal computer-based signal processing and image reconstruction unit using MATLAB. The improved antenna comprises of four-unit cells along one axis, where an individual unit cell integrates a balancing SRR and CLS pair, which makes the antenna radiation omnidirectional over the operating frequencies. The electrical dimensions of this proposed antenna are 0.28λ × 0.20λ × 0.016λ, measured at the lowest operating frequency of 2.97 GHz as the operating bandwidth of this is in between 2.97⁻15 GHz (134.82% bandwidth), with stable directional radiation pattern. SP8T 8 port switch is used to enable the eight receiver antennas to sequentially send a 3⁻8.0 GHz microwave signal to capture the backscattered signal by MATLAB software. A low-cost realistic homogeneous breast phantom with tumor material is developed and measured to test the capability of the imaging system to detect the breast tumors. A post-processing delay-multiply-and-sum (DMAS) algorithm is used to process the recorded backscatter signal to get an image of the breast phantom, and to accurately identify the existence and located area of multiple breast tumor tissues.
    Matched MeSH terms: Humans
  7. Fulltext Generation-y employees and their perceptions of work-life balance
    Bahrain, Mos, Nur Fatihah Abdullah, Bandar, Surena, Sabil, Farida, Abdul Halim, Agatha Lamentan, Muda, Hana, Hamidi, et al.
    Journal of Cognitive Sciences & Human Development, 2018;4(2):28-41.
    MyJurnal
    The objective of this study is to identify the perceptions of Generation Y employees regarding
    work-life balance practices. As increasing numbers of Generation Y enter the workforce,
    questions regarding how they perceive work, family and self-related issues, challenges and
    coping strategies in balancing personal and professional commitments became issues of interests
    for employers. This study uses interviews to collect data from six informants in Generation
    Y and the data were analyzed through content analysis. The results indicate that Generation
    Y employees do indeed have issues and challenges with balancing work and family.
    However, unlike the older generation of employees, Generation Y employees perceive managing
    work-life balance only through segmentation or separation strategies. This particular
    finding indicates that if organizations want to attract and retain these employees they should
    adapt a strategy specifically designed to target this employee group.
    Matched MeSH terms: Humans
  8. Does Vitamin D reduce disease activity in people with multiple sclerosis? A Cochrane Review summary with commentary
    Engkasan JP
    NeuroRehabilitation, 2019;45(1):135-136.
    PMID: 31403951 DOI: 10.3233/NRE-189008
    The aim of this commentary is to discuss in a rehabilitation perspective the recently published Cochrane Review "Vitamin D for the management of multiple sclerosis" by Jagannath et al. (2018)1 under the direct supervision of Cochrane Multiple Sclerosis and rare diseases of the CNS Group. This Cochrane Corner is produced in agreement with NeuroRehabilitation by Cochrane Rehabilitation.
    Matched MeSH terms: Humans
  9. Fulltext Late onset mania post dengue fever in an elderly patient: a case report
    Tengku Mohd Saifuddin, Aida Farina Ismail, Noorul Amilin Harun
    Malaysian Journal of Psychiatry, 2018;27(1):0-0.
    MyJurnal
    Manic symptoms secondary to post dengue fever are rare or might be underreported. Awareness of this phenomenon is important for therapeutic
    considerations of patients. We present a case of late onset mania in an elderly
    gentleman who developed manic symptoms post dengue fever.
    Matched MeSH terms: Humans
  10. Stature estimation in the South-East Asian population: A systematic review
    Ismail NA, Abu Bakar SN, Abdullah N, Shafie MS, Mohd Nor F
    Malays J Pathol, 2019 Aug;41(2):83-89.
    PMID: 31427544
    INTRODUCTION: Stature estimation is population dependent, and population-specific regression equations should be generated for accurate anthropological assessments. Nevertheless, stature estimation data was inaccessible and limited in some of the South-East Asian countries. The systematic review was conducted to analyse the regression equations of stature estimations developed in South-East Asian region.

    MATERIALS AND METHODS: A systematic literature search was performed through SCOPUS database and Google Scholar from January till March 2018. All published articles which developed stature estimation from different types of bone, methods and type of statures (i.e. living stature, forensic stature and cadaveric stature) were included in this study. Risks of biases were also assessed. Population studies with no regression equations were excluded from the study.

    RESULTS: Seven studies that met the inclusion criteria were identified. In the South-East Asia region, regression equations for stature estimation were developed in Thailand and Malaysia. In these studies, bone measurements were done either by radiography, direct bone measurement, or palpation on body surface for anatomical bony prominence. All of these studies used various parts of bones for stature estimation.

    CONCLUSION: The most widely used regression equations for stature estimation in South-East Asian population were from the Thailand population. Further research is recommended to develop regression equations for other South-East Asian countries.

    Matched MeSH terms: Humans
  11. [Mycobacterial lung infection in 8 patients with AIDS: clinical and radiological features]
    Kawana A, Toyota E, Kobayashi N, Kudo K, Genka I, Aoki M, et al.
    Kansenshogaku Zasshi, 1998 Mar;72(3):238-44.
    PMID: 9585697
    The prevalence of mycobacterial infection in AIDS patients has increased in Japan. This report describes details of the clinical and radiological features of eight AIDS patients with mycobacterial disease (6 with M. tuberculosis infection and 2 with M. kansasii infection) in our hospital during the period from October 1995 through February 1997. Six of the 8 were men, and two were women. The mean age was 36.5 years. Six were Japanese, one was from Myanmar, and one was Malaysian. The median CD4 positive T lymphocyte counts (CD4 count) at the time of diagnosis of the M. tuberculosis was 75.5 (range 14-569/microliter, and the M. kansasii was 21.5 (range 19-24)/microliter. Clinical findings and symptoms of all patients were non-specific, but almost all patients had a cough and fever. In the radiographic findings, the patients of the M. tuberculosis group presented multiple hilar and mediastinal lymphadenopathy, miliary shadow, and obstructive pneumonia. Both M. kansasii patients showed a multiple infiltration shadow. There were no drug resistant strains in M. tuberculosis except on isolate with moderate resistant. to Streptomycin. These observations suggest that AIDS-associated mycobacterial disease shows atypical clinical and radiological features in some cases, especially in advanced stages of AIDS. Therefore, we need to recognize the characteristics of the clinical and radiological features of the patients with mycobacterial diseases and AIDS.
    Matched MeSH terms: Humans
  12. Fulltext Perceptions of physicians about clinical pharmacist’s role in Al Qassim’s hospitals in Saudi Arabia
    Ahmed NO, Alrebdi SF, Abdulghani MAM, Baobaid MF
    Malaysian Journal of Public Health Medicine, 2017;17(3):109-116.
    The objective of this study is to explore physician’s perception toward clinical pharmacy services and role of clinical pharmacists in governmental hospitals at Al-Qassim region. An observational cross-sectional survey was conducted. Results: 150 males and 39 females participated giving 75.5% (189 of 250) response rate. Physicians perceptions were found to be high (equal or more than 90% of frequency) in some clinical pharmacy services such as patients’ education and counselling, monitoring of patients’ responses to drug therapy including toxicity/side effects and provision of drug information to healthcare professionals. The physicians showed low perception (less than 76%) in the taking of patients’ medication history on admission, by clinical pharmacists. Conclusion: Physicians’ perception toward clinical pharmacy services and the role of clinical pharmacists was not found to be completely favourable. The reason of this mixed responses and to the accommodating feelings of clinical pharmacy services in clinical setting appear to relate to the state of infrastructure and environments of hospitals. The infrastructure and environments of hospitals need to be updated for an improved accommodation clinical pharmacy services.
    Matched MeSH terms: Humans
  13. Fulltext Isolated sphenoid sinusitis: A big headache
    Ishak NL, Subha ST, Abu Bakar S
    Malays Fam Physician, 2019;14(1):29-30.
    PMID: 31289629
    Matched MeSH terms: Humans
  14. Prince of Songkhla--a new dental faculty
    Bramley P
    Br Dent J, 1990 Jun 09;168(11):426-7.
    PMID: 2361077
    The sophisticated cities, the ancient culture, splendid hotels, wonderful beaches, the variety of food, the beautiful people, the predictable climate and above all the smiling friendliness of the Thais make up some of the exotic attractions extolled by Thailand's tourist industry. For the last 8 years, through the good offices of British Council, several British academics have appreciated all that but have also had the privilege of working alongside Thai colleagues in a much more down-to-earth mode. In 1980 the Thai Government decided that a dental faculty with a target output of 40 DDS graduates per annum should be set up at the Prince of Songkhla University at Hadyai, a town of some 100,000 inhabitants about 1000 km south of Bangkok near the Malaysian border. The university itself is modern, situated on a splendid campus and has a well-established medical faculty. At that time, there were, in Thailand, four dental faculties: two in Bangkok, one in Chiang Mai and one at Khon Kaen. Prince of Songkhla was to be the fifth.
    Matched MeSH terms: Humans
  15. Health beliefs about osteoporosis in a Malaysian population. [Abstract]
    Yeap SS, Goh EML, Das Gupta E, Lee JK
    APLAR Journal of Rheumatology, 2006;9 Suppl 1:A125-A126.
    DOI: 10.1111/j.1479-8077.2006.00199_20.x
    Aims: The aim of this study was to determine the depth of knowledge about osteoporosis (OP) among the public in Malaysia. Methods: A self-administered questionnaire was distributed to attendees of selected health-related public forums in the Klang Valley and Seremban between the months of May to October 2005. Results: 483 questionnaires were returned from 600 given out (80.5%). There were 139 (28.8%) male, 338 (70%) female respondents and 6 (1.2%) not stated. 87.1% respondents had heard of OP. Significantly more women than men had heard of OP (p = 0.015). Mean age was 50.15 ± 14.6 years, 56.7% in the range of 45-64 years. There was no significant difference in the ages of those who had heard of OP and those who had not. 180/338 (53.3%) were postmenopausal females. Those with >10 years of schooling were more likely to have heard of OP (p RM 1000/month (US$270) were more likely to have heard of OP (p =0.022). 22.6% had a positive family history of OP. 63.1% exercised regularly at an average of 4.26 ± 2.78 hours/week. 4.8% were smokers with a median of 10 cigarettes/day. 24.4% drank alcohol with a median of 1 drink/week. However, 70.9% of respondents said that OP led to falls. 89.6% were concerned about osteoporosis. 90.7% agreed that osteoporosis would make daily activities more difficult. The majority obtained their information about osteoporosis from the printed word; newspapers 55.7%, magazines 46.4%, posters/brochures 30.2%, followed by public talks 30%, relatives 29.6%, television 22.8%, medical clinic 22.6% and internet 11.4%. The majority would ask for more information on osteoporosis from their general practitioner 30.6%, followed by other medical specialists such as orthopaedic surgeons 28.4%, hospital specialists 23.8%, rheumatologists 22.4%, followed by friends 15.9%, relatives 14.3% and pharmacists 11.4%. In this self-selected population, knowledge of OP was better among women, the better educated and those earning a higher level of income. Almost 90% of respondents were concerned about getting OP. Their knowledge of OP was obtained from the printed word, which is an important consideration when considering health promotion activities. General practitioners and orthopaedic surgeons need to have a good knowledge of OP.
    Matched MeSH terms: Humans
  16. Teaching NeuroImages: Neuroimaging in hemiplegic migraine
    Tee TY, Khoo CS, Raymond AA, Syazarina SO
    Neurology, 2019 08 06;93(6):e626-e627.
    PMID: 31383811 DOI: 10.1212/WNL.0000000000007905
    Matched MeSH terms: Humans
  17. Cross-cultural adaptation and validation of the Malay health assessment questionnaire for use in rheumatoid arthritis
    Hussein H, Mustafa R, Quek KF, Hassanudin NS, Shahid S
    Int J Rheum Dis, 2008;11(3):237-240.
    DOI: 10.1111/j.1756-185X.2008.00384.x
    Objective: To validate the Malay version of the Health Assessment Questionnaire (Malay-HAQ) for use in Malay-speaking rheumatoid arthritis (RA) patients in the Malaysian setting. The HAQ - Disability Index has been validated in several languages, but not in Malay.Methods: The original HAQ was modified and translated into Malay by two translators, one of whom was aware of the objectives of the Questionnaire and the other as a lay translator. Two sets of Malay-HAQ were distributed to RA patients during their routine follow-up visits; one set to be completed immediately and another set to be completed 2 weeks later. A total of 61 patients completed the two sets of Malay-HAQ. The data collected was analysed using SPSS V. 11.0. Reliability of the data was evaluated using the test-retest method and internal consistency was assessed by Cronbach's alpha.Results: The study showed that the Malay-HAQ is feasible and reliable. The Spearman's correlation coefficient ranged from 0.65 to 0.82, while the internal consistency was 0.88-0.92.Conclusion: The Malay-HAQ is a sensitive, reliable and valid instrument for the measurement of functional status in RA patients in a Malay setting. © 2008 Asia Pacific League of Associations for Rheumatology.
    Matched MeSH terms: Humans
  18. Fulltext Using bootstrapped quantile regression analysis for small sample research in applied linguistics: Some methodological considerations
    Nikitina L, Paidi R, Furuoka F
    PLoS One, 2019;14(1):e0210668.
    PMID: 30640925 DOI: 10.1371/journal.pone.0210668
    Quantitative applied linguistics research often takes place in restricted settings of an intact language classroom, workplace, phonetics laboratory or longitudinal sample. In such settings the samples tend to be small, which raises several methodological problems. The main aim of the current paper is to give a detailed explanation of methodological and practical implications inherent in a robust statistical method called bootstrapped quantile regression (BQR) analysis. Importantly for applied linguistics research, the BQR method could help to deal with methodological difficulties inherent in small sample studies. The current study employed a moderately small sample (N = 27) of students learning the Japanese language in a Malaysian public university. It examined the relationships between the students' language learning motivation (specifically, integrative orientation), the students' images or stereotypes about Japan and their global attitudes toward the target language country and its people. The findings indicated that there was a statistically significant relationship between the students' attitudes toward the target language country and their integrative orientation. In addition, these attitudes were found to be the most constant determinant of the integrative orientation. Besides the applied linguistics research, the BQR method can be used in a variety of the human sciences research where a sample size is small.
    Matched MeSH terms: Humans
  19. Carbon Nanomaterial-Based Electrochemical Biosensors for Foodborne Bacterial Detection
    Muniandy S, Teh SJ, Thong KL, Thiha A, Dinshaw IJ, Lai CW, et al.
    Crit Rev Anal Chem, 2019;49(6):510-533.
    PMID: 30648398 DOI: 10.1080/10408347.2018.1561243
    The development of easy to use, rapid and sensitive methods for direct detection of foodborne bacterial pathogens has become significantly important due to their impact on human health. In recent years, carbon nanomaterials have been adapted in the fabrication of electrochemical biosensors due to their exceptional combination of intrinsic properties such as high conductivity, stability and biocompatibility that render them as a promising candidate for bio-sensing material. The scope of this review is to provide a brief history of the current methods and different types of electrochemical biosensors used for the detection of bacterial pathogens. We primarily focus on the recent progress and applications of graphene, carbon nanotubes and their derivatives in electrochemical biosensors for foodborne bacterial pathogens detection. Finally, the status and future prospects of carbon-based electrochemical biosensors are also reviewed and discussed.
    Matched MeSH terms: Humans
  20. High prevalence of poor sleep quality among secondary school students in Malaysia
    Vignesh R, Ganesh SS, Vengata Subramani M, Ravindran M, Abdul Karim RH
    Med J Malaysia, 2018 12;73(6):444.
    PMID: 30647230
    No abstract provided.
    Matched MeSH terms: Humans
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