Displaying publications 821 - 840 of 5421 in total

Abstract:
Sort:
  1. Bailout left main bioresorbable vascular scaffolding for the treatment of iatrogenic coronary dissection induced by guiding catheter and sticky ABSORB bioresorbable vascular scaffold balloon
    Yew KL
    Int J Cardiol, 2015;187:527-9.
    PMID: 25846666 DOI: 10.1016/j.ijcard.2015.03.432
    Matched MeSH terms: Coronary Artery Disease/surgery; Coronary Artery Disease/therapy*; Iatrogenic Disease
  2. Search for monotop signatures in proton-proton collisions at √s=8  TeV
    Khachatryan V, Sirunyan AM, Tumasyan A, Adam W, Bergauer T, Dragicevic M, et al.
    Phys Rev Lett, 2015 Mar 13;114(10):101801.
    PMID: 25815923
    Results are presented from a search for new decaying massive particles whose presence is inferred from an imbalance in transverse momentum and which are produced in association with a single top quark that decays into a bottom quark and two light quarks. The measurement is performed using 19.7  fb^{-1} of data from proton-proton collisions at a center-of-mass energy of 8 TeV, collected with the CMS detector at the CERN LHC. No deviations from the standard model predictions are observed and lower limits are set on the masses of new invisible bosons. In particular, scalar and vector particles, with masses below 330 and 650 GeV, respectively, are excluded at 95% confidence level, thereby substantially extending a previous limit published by the CDF Collaboration.
    Matched MeSH terms: Disease Vectors
  3. A novel 2-step approach combining the NAFLD fibrosis score and liver stiffness measurement for predicting advanced fibrosis
    Chan WK, Nik Mustapha NR, Mahadeva S
    Hepatol Int, 2015 Oct;9(4):594-602.
    PMID: 25788185 DOI: 10.1007/s12072-014-9596-7
    BACKGROUND: The non-alcoholic fatty liver disease (NAFLD) fibrosis score (NFS) is indeterminate in a proportion of NAFLD patients. Combining the NFS with liver stiffness measurement (LSM) may improve prediction of advanced fibrosis. We aim to evaluate the NFS and LSM in predicting advanced fibrosis in NAFLD patients.

    METHODS: The NFS was calculated and LSM obtained for consecutive adult NAFLD patients scheduled for liver biopsy. The accuracy of predicting advanced fibrosis using either modality and in combination were assessed. An algorithm combining the NFS and LSM was developed from a training cohort and subsequently tested in a validation cohort.

    RESULTS: There were 101 and 46 patients in the training and validation cohort, respectively. In the training cohort, the percentages of misclassifications using the NFS alone, LSM alone, LSM alone (with grey zone), both tests for all patients and a 2-step approach using LSM only for patients with indeterminate and high NFS were 5.0, 28.7, 2.0, 2.0 and 4.0 %, respectively. The percentages of patients requiring liver biopsy were 30.7, 0, 36.6, 36.6 and 18.8 %, respectively. In the validation cohort, the percentages of misclassifications were 8.7, 28.3, 2.2, 2.2 and 8.7 %, respectively. The percentages of patients requiring liver biopsy were 28.3, 0, 41.3, 43.5 and 19.6 %, respectively.

    CONCLUSIONS: The novel 2-step approach further reduced the number of patients requiring a liver biopsy whilst maintaining the accuracy to predict advanced fibrosis. The combination of NFS and LSM for all patients provided no apparent advantage over using either of the tests alone.

    Matched MeSH terms: Disease Progression; Non-alcoholic Fatty Liver Disease/complications; Non-alcoholic Fatty Liver Disease/physiopathology
  4. Fulltext Homocysteine, folate, vitamin B12, and cardiovascular risk in Indians, Malays, and Chinese in Singapore
    Hughes K, Ong CN
    J Epidemiol Community Health, 2000 Jan;54(1):31-4.
    PMID: 10692959
    OBJECTIVE: To examine the hypothesis that the higher rates of coronary heart disease (CHD) in Indians (South Asians) compared with Malays and Chinese is partly attributable to differences in blood concentrations of homocysteine, and related blood concentrations of folate and vitamin B12.
    DESIGN: Cross sectional study of the general population.
    SETTING: Singapore.
    PARTICIPANTS: Random sample of 726 fasting subjects aged 30 to 69 years.
    MAIN RESULTS: Mean plasma total homocysteine concentrations did not show significant ethnic differences; values were Indians (men 16.2 and women 11.5 mumol/l), Malays (men 15.0 and women 12.5 mumol/l), and Chinese (men 15.3 and women 12.2 mumol/l). Similarly, the proportions with high plasma homocysteine (> 14.0 mumol/l) showed no important ethnic differences being, Indians (men 60.0 and women 21.9%), Malays (men 53.9 and women 37.8%), and Chinese (men 56.6 and women 30.6%). Mean plasma folate concentrations were lower in Indians (men 8.7 and women 10.9 nmol/l) and Malays (men 8.5 and women 10.8 nmol/l), than Chinese (men 9.7 and women 13.8 nmol/l). Similarly, the proportions with low plasma folate (< 6.8 nmol/l) were higher in Indians (men 44.9 and women 36.6%) and Malays (men 45.3 and women 24.5%) than Chinese (men 31.4 and women 12.6%). Mean plasma vitamin B12 concentrations were lowest in Indians (men 352.5 and women 350.7 pmol/l), then Chinese (men 371.1 and women 373.7 pmol/l), and then Malays (men 430.5 and women 486.0 pmol/l).
    CONCLUSION: While there were ethnic differences for plasma folate and vitamin B12 (in particular lower levels in Indians), there was no evidence that homocysteine plays any part in the differential ethnic risk from CHD in Singapore and in particular the increased susceptibility of Indians to the disease.
    Matched MeSH terms: Coronary Disease/blood; Coronary Disease/ethnology*; Disease Susceptibility
  5. Fulltext Assessment and management of chronic cough
    Wong CMM, Lim KH, Liam CK
    Med J Malaysia, 2002 Dec;57(4):515-23; quiz 524-5.
    PMID: 12733182
    Matched MeSH terms: Chronic Disease
  6. Vitamin E in cardiovascular disease: has the die been cast?
    Yusoff K
    Asia Pac J Clin Nutr, 2002;11 Suppl 7:S443-7.
    PMID: 12492632
    Cardiovascular disease, in particular coronary artery disease (CAD), remains the most important cause of morbidity and mortality in developed countries and, in the near future, more so in the developing world. Atherosclerotic plaque formation is the underlying basis for CAD. Growth of the plaque leads to coronary stenosis, causing a progressive decrease in blood flow that results in angina pectoris. Acute myocardial infarction and unstable angina were recently recognised as related to plaque rupture, not progressive coronary stenosis. Acute thrombus formation causes an abrupt coronary occlusion. The characteristics of the fibrin cap, contents of the plaque, rheological factors and active inflammation within the plaque contribute to plaque rupture. Oxidative processes are important in plaque formation. Oxidized low density lipoproteins (LDL) but not unoxidized LDL is engulfed by resident intimal macrophages, transforming them into foam cells which develop into fatty streaks, the precursors of the atherosclerotic plaque. Inflammation is important both in plaque formation and rupture. Animal studies have shown that antioxidants reduce plaque formation and lead to plaque stabilisation. In humans, high intakes of antioxidants are associated with lower incidence of CAD, despite high serum cholesterol levels. This observation suggests a role for inflammation in CAD and that reducing inflammation using antioxidants may ameliorate these processes. Men and women with high intakes of vitamin E were found to have less CAD. Vitamin E supplementation was associated with a significant reduction in myocardial infarction and cardiovascular events in the incidence of recurrent myocardial infarction. In the hierarchy of evidence in evidence-based medicine, data from large placebo-controlled clinical trials is considered necessary. Results from various mega-trials have not shown benefits (nor adverse effects) conferred by vitamin E supplementation, suggesting that vitamin E has no role in the treatment of CAD. These results do not seem to confirm, at the clinical level, the effect of antioxidants against active inflammation during plaque rupture. However, a closer examination of these studies showed a number of limitations, rendering them inconclusive in addressing the role of vitamin E in CAD prevention and treatment. Further studies that specifically address the issue of vitamin E in the pathogenesis of atherosclerosis and in the treatment of CAD need be performed. These studies should use the more potent antioxidant property of alpha-tocotrienol vitamin E.
    Matched MeSH terms: Coronary Artery Disease/etiology*; Coronary Artery Disease/metabolism; Coronary Artery Disease/prevention & control
  7. Vestibular nerve section in a child with intractable Menière's disease
    See GB, Mahmud MR, Zurin AA, Putra SH, Saim LB
    Int J Pediatr Otorhinolaryngol, 2002 May 31;64(1):61-4.
    PMID: 12020915
    Clinical presentation of Menière's disease in children is not as typical as in adults. The triad of vertigo, tinnitus and deafness are not usually elicited, diagnosis often being made after years of follow up and batteries of investigation. A case of Menière's disease in a 3-year-old boy is presented. The diagnosis was only obvious at the age of 8 when the triad of vertigo, deafness and tinnitus were present. His disease progressed despite a trial of intratympanic gentamicin injections and endolymphatic sac decompression. Vestibular nerve section was subsequently performed for his intractable disease. Following the procedure he was asymptomatic and able to attend school.
    Matched MeSH terms: Meniere Disease/complications; Meniere Disease/drug therapy; Meniere Disease/surgery*
  8. Current status of coronary risk factors among rural Malays in Malaysia
    Nawawi HM, Nor IM, Noor IM, Karim NA, Arshad F, Khan R, et al.
    J Cardiovasc Risk, 2002 Feb;9(1):17-23.
    PMID: 11984213
    Coronary heart disease (CHD) is the leading cause of death in Malaysia, despite its status as a developing country. The rural population is thought to be at low risk.
    Matched MeSH terms: Coronary Disease/blood; Coronary Disease/etiology*; Coronary Disease/epidemiology*
  9. The goat as a model for studies of pneumonic pasteurellosis caused by Pasteurella multocida
    Zamri-Saad M, Effendy WM, Maswati MA, Salim N, Sheikh-Omar AR
    Br. Vet. J., 1996 Jul;152(4):453-8.
    PMID: 8791853
    A model of pneumonic pasteurellosis has been established in goats using Pasteurella multocida harvested from pneumonic lungs of goats (types A and D), rabbits (type A) and sheep (type D). The resultant infections were acute, subacute or chronic. The gross and histological lesions of the subacute and chronic infections were typical of pneumonic pasteurellosis. P. multocida type D produced significantly (P < 0.01) more severe lesions when compared with other isolates. There were strong correlations between the clinical signs and the severity of lesions.
    Matched MeSH terms: Acute Disease; Chronic Disease; Disease Models, Animal*
  10. Inborn errors of metabolic diseases in Malaysia: a preliminary report of maple syrup urine diseases for 1993
    Zakiah I, Ashikin YN, Aisiah SM, Ismail HI
    Southeast Asian J. Trop. Med. Public Health, 1995;26 Suppl 1:134-6.
    PMID: 8629092
    The Malaysian level of health care has greatly improved so that many of the infectious diseases are now under control. However, perinatal death or death due to unknown childhood diseases remains high (10.3%) being second on the list of causes of death amongst Malaysians. Could inborn metabolic diseases be the main cause of death among these children? Recently, with our success in the development of confirmatory techniques for amino acid disorders using high performance liquid chromatography (HPLC), we have examined 404 samples received from all over the country in 1993. Each specimen with abnormal findings from screening tests by one-dimensional thin layer chromatography was confirmed using HPLC. 41% had generalized aminoacidurias and 4.2% had maple syrup urine disease (MSUD). Patients were aged between 11 days to 6 years. Most of them were Malay males and presented with a history suggestive of MSUD. With this preliminary finding, further studies will be carried out in order to have an investigation and management protocol for the diseases and more importantly to formulate a strategy of screening for the country.
    Matched MeSH terms: Maple Syrup Urine Disease/diagnosis*; Maple Syrup Urine Disease/metabolism; Maple Syrup Urine Disease/epidemiology
  11. Fulltext Chronic osteomyelitis due to Burkholderia pseudomallei
    Kareem BA, Aiyar S, Marshal DS
    Med J Malaysia, 1995 Mar;50(1):116.
    PMID: 7752966
    Matched MeSH terms: Chronic Disease
  12. Fulltext Acute suppurative dacryoadenitis
    Krishnasamy M, Chandran S
    Med J Malaysia, 1987 Jun;42(2):137-8.
    PMID: 3503190
    Acute dacroadenitis is a rare condition. This case illustrates the acute onset, typical pain and tenderness in the upper outer eye of an enlarged lacrimal gland with purulent discharge. Good response to antibiotics is usual.
    Matched MeSH terms: Acute Disease
  13. Cardiovascular disease in a West Malaysian town. A survey in general practice
    Balasundaram R
    Trans R Soc Trop Med Hyg, 1970;64(4):607-14.
    PMID: 5485621 DOI: 10.1016/0035-9203(70)90085-4
    The pattern and incidence of cardiovascular disease was studied in a general practice in an urban-rural area in the west coast of West Malaysia. Hypertension, rheumatic heart disease and congenital heart disease accounted for 85% of the 476 patients with evidence of cardiovascular disease. Ischaemic heart disease, arteriosclerotic heart disease and other conditions accounted for the rest. Emphasis is laid on the salient features of incidence in general practice. Comparison is made with previous clinical and pathological studies from this region.
    Study site: General practjce clinic, Telok Anson [Teluk Intan], District of Lower Perak, Malaysia
    Matched MeSH terms: Coronary Disease/epidemiology; Rheumatic Heart Disease/epidemiology
  14. Acute arterial embolism
    Saw HS
    Med J Malaysia, 1977 Dec;32(2):157-60.
    PMID: 614484
    Matched MeSH terms: Acute Disease
  15. Fulltext Anatomical variations of thenar muscle of hand, among Cadavers In Universiti Putra Malaysia (UPM)
    Che Norma Mat Taib, Jegathis Prushothuman, Muhammad Adib Farhan Abdullah, Mohamad Aris, Mohd Moklas
    Malaysian Journal of Medicine and Health Sciences, 2019;15(107):86-86.
    MyJurnal
    Introduction: Detailed information of structural and functional anatomy of thenar muscle is very significant in order to improve diagnostic and various conditions of hand surgeries so that the function of hand movement can be re-stored and to prevent further iatrogenic injuries. Methods: In this study, fifty hands were dissected to determine the variation in each of the thenar muscle. Results: Only the abductor pollicis brevis showed significant findings. Normal formation of one belly in abductor pollicis brevis represented 72.0% (18) and 84.0% (21) for the left and right hands, respectively. Variations according to the number of belly of the abductor pollicis brevis were also observed. One of the variations is the absence of the abductor pollicis brevis, 4.0% (1) in the right hand. Two belly formations of abductor pollicis brevis were observed, 28.0% (7) and 12.0% (3) for left and right sides of hand respectively. Thus, more variations were observed to occur on the left hand (7) compared to the right hand (4). Many studies describe about the variations of each thenar muscle, but few literatures were found discussing on the association of thenar muscle variation with the sides of hand. Using the Fisher Exact Test, it showed that there was no significant associa-tion of variations in the thenar muscle in relation to the sides of hand. Conclusion: This study conclude that there is no consistency between variations of the thenar muscle in relation to the sides of hand. However, clinical awareness of these variations is important in the context of compartment syndrome, use of the aberrant structures as grafting material in reconstructive surgery and proper interpretation of imaging modalities.
    Matched MeSH terms: Iatrogenic Disease
  16. Fulltext Fractal-Fractional Mathematical Model Addressing the Situation of Corona Virus in Pakistan
    Shah K, Arfan M, Mahariq I, Ahmadian A, Salahshour S, Ferrara M
    Results Phys, 2020 Dec;19:103560.
    PMID: 33200064 DOI: 10.1016/j.rinp.2020.103560
    This work is the consideration of a fractal fractional mathematical model on the transmission and control of corona virus (COVID-19), in which the total population of an infected area is divided into susceptible, infected and recovered classes. We consider a fractal-fractional order

    SIR

    type model for investigation of Covid-19. To realize the transmission and control of corona virus in a much better way, first we study the stability of the corresponding deterministic model using next generation matrix along with basic reproduction number. After this, we study the qualitative analysis using "fixed point theory" approach. Next, we use fractional Adams-Bashforth approach for investigation of approximate solution to the considered model. At the end numerical simulation are been given by matlab to provide the validity of mathematical system having the arbitrary order and fractal dimension.
    Matched MeSH terms: Disease Susceptibility
  17. Meteorological multivariable approximation and prediction with classical VAR-DCC approach
    Siti Mariam Norrulashikin, Fadhilah Yusof, Ibrahim Lawal Kane
    Sains Malaysiana, 2018;47:409-417.
    The vector autoregressive (VAR) approach is useful in many situations involving model development for multivariables
    time series. VAR model was utilised in this study and applied in modelling and forecasting four meteorological variables.
    The variables are n rainfall data, humidity, wind speed and temperature. However, the model failed to address the
    heteroscedasticity problem found in the variables, as such, multivariate GARCH, namely, dynamic conditional correlation
    (DCC) was incorporated in the VAR model to confiscate the problem of heteroscedasticity. The results showed that the use
    of the VAR coupled with the recognition of time-varying variances DCC produced good forecasts over long forecasting
    horizons as compared with VAR model alone.
    Matched MeSH terms: Disease Vectors
  18. Fulltext Life After Covid19: The New Normal
    Mohd Yusof Ibrahim, Sadia Choudhury Shimmi
    Borneo Journal of Medical Sciences, 2020;14(2):1-3.
    MyJurnal
    “If you hear of an outbreak of plague in a land, do not enter it; if the plague breaks out in a place while you are in it, do not leave that place”, reported by Sahih Al-Bukhari. This was the phrase quoted by Prophet Muhammad 14 centuries ago concerning both in disease spread and prevention. The relevancy of this statement is now widely seen and surge by the social media in a hashtag of “stay home” on an international level due to pandemic of COVID-19 disease.
    Matched MeSH terms: Disease Outbreaks
  19. Fulltext Molecular and pathogenicity of infectious bronchitis virus (Gammacoronavirus) in Japanese quail (Coturnix japonica)
    Fadhilah AS, Kai TH, Lokman HI, Yasmin NAR, Hafandi A, Hasliza AH, et al.
    Poult Sci, 2020 Jun;99(6):2937-2943.
    PMID: 32475428 DOI: 10.1016/j.psj.2020.01.026
    Infectious bronchitis virus (IBV) infection is highly infectious respiratory disease in poultry industry with significant economic importance. The prevalence of IBV in quail industry in Malaysia was not well documented; therefore, its actual role in the epidemiology of the disease is relatively unknown. This study was to determine the susceptibility of Japanese quail, as one of the species in commercial poultry industry, toward IBV. In addition, it will also give a potential impact on the overall health management in the quail industry even though it had been established that quail are resistant to diseases affecting poultry. Moreover, to the best of our knowledge, it is the first experimental study on IBV inoculation in quail. In this experimental study, 20 quails were divided into 4 groups (n = 5 for group A, B, and C, n = 5 for control group). The quails in group A, B, and C were infected via intraocular and intranasal routes with 0.2 mL of 10 × 5 EID50 of the virus. Clinical signs, gross lesions, positive detection of virus, and trachea histopathological scoring were used to assess the susceptibility of these Japanese quails. The results have indicated mild ruffled feathers and watery feces in these inoculated birds. Trachea, lung, and kidney were subjected to one-step reverse transcription polymerase chain reaction for virus detection. The virus was found from trachea and lung samples, whereas it was absent from all kidney samples. Only 3 quails were found with gross lesions. There was a significant difference of tracheal lesion by 0.009 ± 0.845 (P < 0.05) within the treatment groups. In summary, Japanese quails might be susceptible to IBV.
    Matched MeSH terms: Disease Susceptibility/epidemiology; Disease Susceptibility/veterinary*; Disease Susceptibility/virology
  20. The economic burden of chronic obstructive pulmonary disease (COPD) in the USA, Europe, and Asia: results from a systematic review of the literature
    Anees Ur Rehman, Ahmad Hassali MA, Muhammad SA, Shah S, Abbas S, Hyder Ali IAB, et al.
    Expert Rev Pharmacoecon Outcomes Res, 2020 Dec;20(6):661-672.
    PMID: 31596632 DOI: 10.1080/14737167.2020.1678385
    Background: Lack of information about economic burden of COPD is a major cause of lack of attention to this chronic condition from governments and policymakers. Objective: To find the economic burden of COPD in Asia, USA and Europe, and to identify the key cost driving factors in management of COPD patients. Methodology: Relevant studies assessing the cost of COPD from patient perspective or societal perspective were retrieved by thoroughly searching PUBMED, SCIENCE DIRECT, GOOGLE SCHOLAR, SCOPUS, and SAGE Premier Databases. Results: In the USA annual per patient direct medical cost and hospitalization cost were reported as $10,367 and $6852, respectively. In Asia annual per patient direct medical cost in Iran, Korea and Singapore was reported as $1544, $3077, and $2335, respectively. However, annual per patient hospitalization cost in Iran, Korea, Singapore, India, China, and Turkey was reported as $865, $1371, $1868, $296, $1477 and $1031, respectively. In Europe annual per patient direct medical cost was reported as $11,787, $10,552, $8644, $8203, $7760, $3190, $1889, $2162, and $2254 in Norway, Denmark, Germany, Italy, Sweden, Greece, Spain, Belgium, and Serbia, respectively. Conclusion: Limiting the disease to early stage and preventing exacerbations may reduce the cost of management of COPD.
    Matched MeSH terms: Pulmonary Disease, Chronic Obstructive/economics*; Pulmonary Disease, Chronic Obstructive/epidemiology; Pulmonary Disease, Chronic Obstructive/therapy
Related Terms
Filters
Contact Us

Please provide feedback to Administrator (afdal@afpm.org.my)

External Links