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Aras Hormon Testosteron dan Progesteron dalam Kelawar Cynopterus brachyotis di Kampus Universiti Kebangsaan Malaysia (Concentration of Testosterone and Progesterone Homones in Cynopterus Brachyotis Bats in the Universiti Kebangsaan Malaysia Campus)

Kong KH, Zubaid A., Alias Bin Kamis

Sains Malaysiana, 1997;26.

Cynopterus brachyotis, a fruit, leaf and nectar eating bat is a common frugivorous bat in Southeast Asia. In the present study, changes in the reproductive hormones of these bats were measured. Bats were captured and blood samples were taken monthly for seven months (January to July 1997) in the surrounding areas of Universiti Kebangsaan Malaysia (UKM) campus in Bangi. The concentration of the reproductive hormones in the blood, such as testosterone (male) and progesterone (female) were measured using ELISA. The results showed that body weight and concentration of reproductive hormones was correlated with the monthly rainfall. Abundance of food during the rainy season was believed to be the important factor in influencing body weight gain and increase in reproductive hormone synthesis.
Cynopterus brachyotis merupakan kelawar frugivor pemakan buah-buahan, daun dan nektar yang lazim di Asia Tenggara. Matlamat penyelidikan ini ialah untuk menentukan aras hormon yang dirembeskan oleh gonad kelawar frugivor ini, Kelawar-kelawar ini telah ditangkap dan diambil sampel darah pada setiap bulan selama tujuh bulan (Januari hingga Julai 1997) di sekitar kampus Universiti Kebangsaan Malaysia (UKM) di Bangi. Aras hormon pembiakan, iaitu testosteron pada kelawar jantan dan progesteron pada betina ditentukan dengan menggunakan kaedah ELISA. Hasil kajian menunjukkan bahawa berat badan dan aras hormon pembiakan berkait rapat dengan jumlah taburan hujan bulanan. Kelimpahan sumber makanan pada masa taburan hujan yang tinggi dipercayai merangsang pertambahan berat badan dan sintesis hormon pembiakan pada kelawar ini.

Matched MeSH terms: Body Weight
Fulltext Arterial stiffness and its association with dyslipidemia

Razman, M.R., Jamaluddin, A.R., Ellyda, M.N., Seikh, F.A.

International Medical Journal Malaysia, 2013;12(2):59-66.
MyJurnal

Cardiovascular diseases (CVD) are the leading cause of mortality in Malaysia as well as in other countries. It is associated with many risk factors, such as increasing age, hypertension, diabetes, dyslipidemia, oxidative stress and autonomic dysfunction and arterial stiffness. The objectives of this study were to measure the prevalence of arterial stiffness and to assess its association with dyslipidemia. Methods: A cross sectional study was conducted in a rural community in Malaysia involving 146 subjects. Data were collected using an interviewer administered questionnaire which included three sections – sociodemographic characteristics, personal profile, and past medical history. In addition, Seca Body Meter (Seca 220) was used to measure height and weight. Sphygmomanometer (OMRON Automatic Blood Pressure Monitor HEM 907) and SphygmoCor-AtCor MM3 SERIAL/RS-232 were used for blood pressure and augmentation index (AIx) measurement. Data were analysed using the SPSS for Windows, Version 18.0. Results: The mean age of respondents was 49.5 years, SD±15.6. The prevalence of arterial stiffness was 23.3% (95% Confidence Interval (CI): 16.44 – 30.16). The prevalence of dyslipidemia was 82.9% (95% CI: 76.79 – 89.01). Multivariate logistic regression revealed that total cholesterol was significantly associated with arterial stiffness (OR=4.56, CI 1.10-18.90). Conclusion: The prevalence of dyslipidemia was high. Despite an insignificant association between dyslipidemia and AIx, there is a significant association between TC level and AIx.

Matched MeSH terms: Body Weight
Fulltext Ascariasis, trichuriasis, and growth of schoolchildren in Northeastern Peninsular Malaysia

Raj SM, Naing NN

Southeast Asian J. Trop. Med. Public Health, 1998 Dec;29(4):729-34.
PMID: 10772554

A study to determine the effect of antihelminthic treatment on growth and nutritional status was undertaken on 103 children in the second grade of primary school, 71 of whom were found to be infected with Ascaris lumbricoides or Trichuris trichiura. The median Ascaris and Trichuris intensities in the infected group were 19,600 (range; 0-488,000) and 2,800 (range; 0-84,600) eggs per gram of feces respectively. Forty-three children harbored both types of worm. Fourteen weeks after two 400 mg doses of albendazole were administered to infected children, the increases in weight, height, weight for age, height for age and weight for height were significantly higher among infected children than controls who were uninfected at baseline. The observed gains were independent of sex and socioeconomic status. Decrease in log transformed Trichuris intensity correlated with increases in weight (r=0.24; p=0.02) and weight for age (r=0.20; p=0.06) but decrease in Ascaris intensity did not correlate with increases in any of the anthropometric parameters. The results suggest that antihelminthic treatment has beneficial short-term effects on growth and nutritional status of a modest magnitude among early primary schoolchildren in the area.

Matched MeSH terms: Body Weight
Fulltext Ascaris and Trichuris do not contribute to growth retardation in primary school children

Lai KP, Kaur H, Mathias RG, Ow-Yang CK

Southeast Asian J. Trop. Med. Public Health, 1995 Jun;26(2):322-8.
PMID: 8629068

To access the effectiveness of the treatment of soil-transmitted helminthiasis (STH) on the growth of primary school children, 353 children were block stratified to receive either mebendazole plus pyrantel oxantel pamoate every three months or a placebo. The children were followed for two years with 89% completing the trial. Follow-up stools indicated that the treatment was efficacious for ascariasis and trichuriasis. There was virtually no hookworm infection. The children were malnourished as measured by the number below -2 SD of height and weight standards. There was no difference in height or weight between the treatment and control groups by sex initially or at the end of two years of follow-up. The treatment of Ascaris and Trichuris had no effect on growth parameters. The effect of STH on growth may be mediated through hookworm infections.

Matched MeSH terms: Body Weight
Fulltext Asperuloside Enhances Taste Perception and Prevents Weight Gain in High-Fat Fed Mice

Ishaq M, Tran D, Wu Y, Nowak K, Deans BJ, Xin JTZ, et al.

Front Endocrinol (Lausanne), 2021;12:615446.
PMID: 33927690 DOI: 10.3389/fendo.2021.615446

Asperuloside is an iridoid glycoside found in many medicinal plants that has produced promising anti-obesity results in animal models. In previous studies, three months of asperuloside administration reduced food intake, body weight, and adipose masses in rats consuming a high fat diet (HFD). However, the mechanisms by which asperuloside exerts its anti-obesity properties were not clarified. Here, we investigated homeostatic and nutrient-sensing mechanisms regulating food intake in mice consuming HFD. We confirmed the anti-obesity properties of asperuloside and, importantly, we identified some mechanisms that could be responsible for its therapeutic effect. Asperuloside reduced body weight and food intake in mice consuming HFD by 10.5 and 12.8% respectively, with no effect on mice eating a standard chow diet. Fasting glucose and plasma insulin were also significantly reduced. Mechanistically, asperuloside significantly reduced hypothalamic mRNA ghrelin, leptin, and pro-opiomelanocortin in mice consuming HFD. The expression of fat lingual receptors (CD36, FFAR1-4), CB1R and sweet lingual receptors (TAS1R2-3) was increased almost 2-fold by the administration of asperuloside. Our findings suggest that asperuloside might exert its therapeutic effects by altering nutrient-sensing receptors in the oral cavity as well as hypothalamic receptors involved in food intake when mice are exposed to obesogenic diets. This signaling pathway is known to influence the subtle hypothalamic equilibrium between energy homeostasis and reward-induced overeating responses. The present pre-clinical study demonstrated that targeting the gustatory system through asperuloside administration could represent a promising and effective new anti-obesity strategy.

Matched MeSH terms: Body Weight/drug effects*
Assessment of growth and feeding practices in children with cleft lip and palate

Gopinath VK, Muda WA

Southeast Asian J. Trop. Med. Public Health, 2005 Jan;36(1):254-8.
PMID: 15906679

Feeding difficulties in cleft lip and palate (CLP) infants is commonly observed and is the most traumatic experience the family has to face. These infants are undernourished and have compromised growth. The purpose of this study was to 1) assess general health and growth parameters in children with CLP and in normal children; and 2) investigate the feeding methods of CLP infants and normal infants. A total of 221 children from birth to six years of both sexes, with CLP (60 children) and normal (161 children) were selected. The CLP and normal children were divided into three subgroups by age. The practice of feeding the infants in subgroup I was assessed using standard piloted questionnaires. The assessment of growth was done at baseline and at six months in all the subgroups.The general well being of the children was assessed by noting the number of common infections. Results showed that a significantly higher percentage of mothers with normal babies (p < 0.01) had a positive attitude towards breast feeding. When compared to normal children, CLP children were more susceptible to infections (p < 0.05) and measured significantly lower on the height growth curve(p < 0.05). Hence, height can be used to monitor growth in CLP children.

Matched MeSH terms: Body Weight
Fulltext Assessment of muscle mass and its association with protein intake in a multi-ethnic Asian population: relevance in chronic kidney disease

Teo BW, Toh QC, Chan XW, Xu H, Li JL, Lee EJ

Asia Pac J Clin Nutr, 2014;23(4):619-25.
PMID: 25516320 DOI: 10.6133/apjcn.2014.23.4.01

Clinical practice guidelines recommend objective nutritional assessments in managing chronic kidney disease (CKD) patients but were developed while referencing to a North-American population. Specific recommendations for assessing muscle mass were suggested (mid-arm circumference, MAC; corrected mid-arm muscle area, cAMA; mid-arm muscle circumference, MAMC). This study aimed to assess correlation and association of these assessments with dietary protein intake in a multi-ethnic Asian population of healthy and CKD patients.

Matched MeSH terms: Body Weight
Assessment of proximate composition and tetrodotoxin content in the muscle of yellow puffer fish, xenopterus naritus (richardson 1848) from Sarawak, Malaysia

Mohd Nor Azman, A., Samsur, M., Mohammed, M., Fasihuddin, B.A.

International Food Research Journal, 2015;22(6):2280-2287.
MyJurnal

This study is to report the proximate compositions as well as tetrodotoxin (TTX) content in the muscles of yellow puffer fish Xenopterus naritus that collected from Kg. Manggut and Kabong, Sarawak. The internal organs of 26 and 20 specimens from Kg. Manggut and Kabong respectively were removed by the local people that had skills and experiences with the preparation of yellow puffer fish. In general, the moisture contents were ranging between 75.2% and 80.6%. X. naritus from Kabong showed higher crude protein contents (88.2% dry weight) than the same species from Kg. Manggut (87.9% dry weight) and not significantly different (p>0.05). X. naritus from Kg. Manggut demonstrated a significantly higher (p

Matched MeSH terms: Body Weight
Assessment of pubertal development in juvenile male rats after sub-acute exposure to bisphenol A and nonylphenol

Tan BL, Kassim NM, Mohd MA

Toxicol Lett, 2003 Aug 28;143(3):261-70.
PMID: 12849686

The effects of bisphenol A and nonylphenol on pubertal development in the intact juvenile/peripubertal male Sprague-Dawley rats was observed in this study from PND23-52/53. Two groups of rats were administered orally with either 100 mg/kg body weight of nonylphenol or bisphenol A. Another group of rats were administered orally with a mixture of 100 mg/kg body weight of nonylphenol and bisphenol A. Control group was administered with the vehicle of Tween-80 with corn oil (1:9 v/v). Observations made in this study included growth, age at preputial separation, thyroid, liver, testis and kidney weight and histology, epididymal and seminal vesicle plus coagulation gland weight. Nonylphenol and bisphenol A have been observed to cause delay in puberty onset as well as testicular damage in the treatment groups when compared to the control; spermatogenesis was affected in most treated rats. Bisphenol A also caused the enlargement of the kidney and hydronephrosis. Administration of nonylphenol and bisphenol A as a mixture has caused less than additive effects.

Matched MeSH terms: Body Weight/drug effects
Fulltext Association of physical activity score with cardio-pulmonary function parameters and VO2 max in healthy young adults of Sabah, Malaysia

Urban John Arnold D’Souza, Vinod Kumar S., Nagesh Chodankar

Malaysian Journal of Medicine and Health Sciences, 2019;15(106):46-46.
MyJurnal

Introduction: Regular physical activity and VO2 max are correlated directly. Physical anthropometry physical ac-tivity, lung function and cardiac parameters such as systolic, diastolic blood pressure and resting heart rate are the important baseline parameters in relation to the a healthy life. In this study, a comprehensive determination of these parameters were planned among the common ethnicities of Sabah. This study in turn aims at making the sedentary people to make physically active and implicate a possible relationship between cardio-respiratory parameters with the physical activity levels. Methods: A total of 385 young adult Sabah, Malaysia college students with n=148 males and n= 237 females were randomly selected from the different colleges in Kota Kinabalu. Ethical clearance was received from Faculty of Medicine & Health Sciences UMS, and the participants were briefed on the procedures with their voluntary consent. IPAQ-Score/Met-Min/Week, BMI, resting heart rate, blood pressure, lung function parameters – forced vital capacity, peak expiratory flow rate etc were estimated by standard techniques. Data was analyzed, a regression analysis and ANOVA was performed to assess the relationship between independent and dependent variables. Results: Physical activity level has a significant correlation with the dependent variables of this study. VO2max is significantly and inversely related to body weight, BMI, blood pressure and pulse rate, whereas physical activity level is directly correlated. A weak positive correlation for VO2 max with lung function parameters.Conclusion: Physical activity, VO2 max and cardio-respiratory parameters; interdependently correlated and regular activity contributed to the rate of oxygen consumption.

Matched MeSH terms: Body Weight
Fulltext Association between anthropometric status, dietary intake and physical activity with bone health status among premenopausal Chinese women in the Klang Valley, Malaysia

Yee, Y.S.S., Zaitun, Y., Chan, Y.M., Norhaizan, M.E.

Malays J Nutr, 2013;19(3):293-302.
MyJurnal

Introduction: There is a lack of information on bone health status of premenopausal women in Malaysia. This study investigated the bone health status of premenopausal women and its associations with anthropometric, dietary and physical activity. Methods: Bone mineral density (BMD) was measured using dual X-ray absorptiometry (DEXA) at the lumbar spine, femoral neck, total hip and total body. Serum osteocalcin, parathyroid hormone (PTH), beta-crosslaps were also determined. Results: A total of 73 Chinese premenopausal women were recruited in the study with a mean age of 39.3 ± 5.0 years. Average BMI, body fat percentage and lean body mass were 22.2 ± 3.4 kg/m2, 33.9 ± 4.6% and 34.5 ± 4.4 kg, respectively. Mean BMD at the spine, total hip, femoral neck, and total body were 1.025 ± 0.118 g/cm2, 0.876 ± 0.109 g/cm2, 0.739 ± 0.110 g/cm2, and 1.061 ± 0.755 g/cm2, respectively. Their serum beta-crosslaps and PTH were within normal range, but serum osteocalcin (8.5 ± 4.2 ng/ ml) was low. On average, calorie intake (1506 ± 427 kcal/ day) was below the Malaysian Recommended Nutrient Intake (RNI) while their calcium intake achieved only 67% of RNI. Their mean metabolic equivalent score (MET) was 771.4 ± 926.1 min/week. Body weight and related indices (BMI, lean mass, fat mass) were significantly positively correlated with BMD at all skeletal sites. Conclusion: The study revealed that Chinese premenopausal women in the Klang Valley have low calcium intake and low level of physical activity.

Matched MeSH terms: Body Weight
Fulltext Association between dietary inflammatory index and body fat percentage among newly diagnosed breast cancer patients

Ng WH, Abu Zaid Z, Mohd Yusof BN, Amin Nordin S, Lim PY

Ann Med, 2023;55(2):2303399.
PMID: 38242100 DOI: 10.1080/07853890.2024.2303399

BACKGROUND: Obesity, particularly excessive body fat, is an established risk factor and substantial prognostic determinant in breast cancer. Recent studies suggested that diet-related inflammation plays a key role in obesity. This study aimed to determine the association between energy-adjusted dietary inflammatory index (E-DII) and body composition, particularly body fat percentage, among patients with newly diagnosed breast cancer.
MATERIALS AND METHODS: This cross-sectional study was conducted on 124 breast cancer outpatients within the first year of diagnosis and yet to commence oncological treatment. Body composition parameters [body weight, body mass index (BMI), body fat percentage, fat mass over fat-free mass ratio (FM/FFM), muscle mass, and visceral fat] were obtained using a bioelectrical impedance analyzer. Body fat percentage was categorized into two groups which were normal (<35%) and high (≥35%). The E-DII was calculated from the validated 165-items Food Frequency Questionnaire (FFQ) and categorized into three groups or tertiles. Multiple logistic regression analysis was used to determine the association between the E-DII and body fat percentage.
RESULTS: Mean body weight, body fat percentage, FM/FFM, and visceral fat increased as E-DII increased from the lowest tertile (T1) to the most pro-inflammatory tertile (T3) (p for trend <0.05). E-DII was positively associated with body fat percentage (OR 2.952; 95% CI 1.154-7.556; p = 0.024) and remained significant after adjustment for cancer stage, age, physical activity, ethnicity, smoking history, and presence of comorbidities. Compared to T1, participants in T3 had a significantly lower consumption of fiber, vitamin A, beta-carotene, vitamin C, iron, thiamine, riboflavin, niacin, vitamin B6, folic acid, zinc, magnesium, and selenium, but a higher intake of total fat, saturated fat, and monounsaturated fatty acids.
CONCLUSIONS: A higher E-DII was associated with increased body fat percentage, suggesting the potential of advocating anti-inflammatory diet to combat obesity among newly diagnosed breast cancer patients.

Matched MeSH terms: Body Weight
Fulltext Association between drinking water sources and diarrhea with malnutrition among kindergarten's children in Baghdad city, Iraq

Hasanain, F.G., Jamsiah, M., Zaleha, M.I., Azmi M. Tamil, Mohammed, A.A.

Malaysian Journal of Public Health Medicine, 2012;12(1):45-48.
MyJurnal

Malnutrition is associated with childhood diseases such as diarrhea or other severe illness. Children who suffer from
repeated episodes of diarrhea are more likely to suffer from malnutrition. In addition, the source of drinking water is
a very important factor affecting the nutritional status. The objective of this study was to find out the prevalence of
malnutrition condition among children aged 3 to 5 years old and the factors associated with it. A cross sectional study
using simple random sampling was conducted among 220 children aged 3 to 5 years old from four kindergartens in
Baghdad city, Iraq. Nutritional assessment was carried out using the indicator weight-for-age z-score based on World
Health Organization cut off points. Acute malnutrition was found in 18.2 % of the respondents. In this study 65 % of
the respondents used tap water to drink as compared to 35 % who used sterilized bottles as source of drinking water.
The environmental factors mainly the source of drinking water was significantly associated with child nutritional
status (p=0.034). The prevalence of diarrhea and admissions to the hospital due to diarrhea were also significantly
associated with malnutrition (p < 0.01, p

Matched MeSH terms: Body Weight
Fulltext Association between eating behaviour and weight gain among primary school children in Bandar Baru Bangi, Selangor

Norliza Ahmad, Munn-Sann Lye, Zalilah Mohd Shariff, Firdaus Mukhtar, Lim Poh Ying

Malaysian Journal of Medicine and Health Sciences, 2019;15(104):86-86.
MyJurnal

Introduction: Childhood obesity is increasing in prevalence in Malaysia. Excess in dietary intake and inadequate physical activity contribute to the development of obesity among children. The objective of this study was to de-termine the association between eating behaviour and excess weight among primary school children in an urban community in Malaysia. Methods: This is a baseline data of a randomized control field trial of a family-based inter-vention to reduce adiposity in overweight and obese children. It involved five primary government schools in Bandar Baru Bangi, Selangor. The inclusion criteria include parent-child dyad; children aged 7 to 10 years with body mass index (BMI) z-score of +1 standard deviation or more. Parents completed the validated self-administered Children Eating Behaviour Questionnaire (CEBQ). This questionnaire assessed children’s eating behaviour that includes food responsiveness, enjoyment of food, emotional overeating, desire to drink, slowness in eating, satiety responsiveness, emotional undereating and food fussiness. The children’s weight and height were measured and the BMI z-score was calculated. The association between CEBQ subscales and obesity was assessed using multiple linear regression, adjusted for sex and family income. Results: One hundred and thirty-four parent-child dyads had participated in this study. The food responsiveness was found to be significant with excess weight (β = 0.094, 95% CI: 0.02-0.17, p= 0.014). Conclusion: The food responsiveness subscale was associated with excess weight. This eating behaviour need to be taken into consideration in the development and implementation of health campaign targeted at the re-duction of childhood obesity.

Matched MeSH terms: Body Weight
Fulltext Association between functional dentition with inadequate calorie intake and underweight in elderly people living in “Pondok” in Kelantan

Seman, K., Abdul Manaf, H., Ismail, A.R.

Archives of Orofacial Sciences, 2007;2(1):10-19.
MyJurnal

This study was to investigate the association between functional dentition with inadequate calorie intake and underweight in elderly people living in “Pondok” in Kelantan. A cross-sectional study participated by 369 elderly people was carried out. A simple random sampling method was utilized for the selection of the subjects. Subjects were interviewed using a structured form to collect information about subjects’ demographic background and self-reported health status. The 24-hour recall method was used to provide information on the subject’s exact food intake during the previous 24 hours. Body mass index was calculated from subjects’ weight and height, followed by oral assessment. The “Nutrical Software” was used for nutrient calculation, followed by SPSS version 11.5 for data analysis. The response rate was 95.6%. Majority of the respondents were female (92.4%). The percentage of subjects who had inadequate calorie intake and underweight was 71.0% and 25.7% respectively. The percentage of edentulism was 81.0%. The proportion of elderly with compromised functional dentition was 48.2% and majority was edentate elderly without wearing any complete dentures or wearing defective dentures, 23.6% and 56.2% respectively, while 20.2% was dentate elderly. The odds of having inadequate calorie intake and getting underweight among elderly with a compromised functional dentition was 3.7 times and 42.0 times respectively, compared to elderly with a non-compromised functional dentition. There was a significant association between inadequate calorie intake and underweight with functional dentition among elderly living in “Pondok” in Kelantan.

Matched MeSH terms: Body Weight
Fulltext Association between household food insecurity and nutritional outcomes among children in Northeastern of Peninsular Malaysia

Ali Naser I, Jalil R, Wan Muda WM, Wan Nik WS, Mohd Shariff Z, Abdullah MR

Nutr Res Pract, 2014 Jun;8(3):304-11.
PMID: 24944776 DOI: 10.4162/nrp.2014.8.3.304

BACKGROUND/OBJECTIVES: The purpose of the study was to investigate the relationship between household food insecurity and nutritional status of children in low-income households. A cross sectional study involved a survey of households (n = 223) receiving the financial assistance.
SUBJECTS/METHODS: Eligible mothers that fulfilled the inclusion criteria such as non-pregnant, non-lactating mothers, aged 18 to 55 years with their youngest children aged 2 to 12 years, were purposively selected. The Radimer/Cornell hunger and food-insecurity instrument was administered and children's height and weight were measured.
RESULTS: About 16.1% of the households were food secure, while 83.9% experienced some kind of food insecurity. Out of food insecure category, 29.6% households were food insecure, 19.3% women were individual food insecure and 35.0% fell into the child hunger category. Education of the mother (P = 0.047), household size (P = 0.024), number of children (P = 0.024), number of children going to school (P = 0.048), total monthly income (P < 0.001), income per capital (P < 0.001), number of household members contributing to the income (P = 0.018) and food expenditure (P = 0.006) were significant risk factors for household food insecurity. The prevalence of underweight, stunting and wasting in children were 61.0%, 61.4% and 30.6% respectively. Based on multinomial logistic regression, children in food-insecure households were 2.15 times more likely to be underweight and three times to be stunted than children in the food-secure households.
CONCLUSIONS: The findings suggest that household food insecurity is associated with the nutritional status of the children in the rural area of Northeastern Peninsular Malaysia.
KEYWORDS: Northeastern Peninsular Malaysia; child hunger; household food insecurity; nutritional status

Matched MeSH terms: Body Weight
Fulltext Association between polymorphisms of insulin and insulin receptor gene with childhood obesity in malay population

Christinal Teh Pey Wen, Nurul Adibah Nizam, Abdul Rahman Jamal, Wan Zurinah Wan Ngah, Chong, Pei Nee, Poh, Bee Koon

Jurnal Sains Kesihatan Malaysia, 2016;14(1):5-9.
MyJurnal

Childhood obesity is a global epidemic, which leads to the increasing number of studies on genetic locations associated with obesity-related traits. Polymorphisms of insulin (INS) gene have been shown to be associated with obesity-related phenotypes in Europeans; while insulin receptor (INSR) gene has been associated with energy regulation. Therefore, this study was conducted to investigate the association between the INS (rs689) and INSR (rs3745551) gene polymorphisms with childhood obesity risk in a Malay childhood population. Normal weight (538) and overweight or obese (557) children aged 6-12 years old were genotyped using semi-automated Sequenom iPLEX® Gold. Body mass index (BMI) was calculated from measured body weight and height. The rs689 (T/T: 0.006, A/T: 0.159 and A/A: 0.835) and rs3745551 (G/G: 0.054, A/G: 0.378 and A/A: 0.568) genotype distributions were consistent with Hardy Weinberg equilibrium. The T-minor allele frequency for rs689 was 8.6% and G-minor allele frequency for rs3745551 was 24.3%. Minor allele of INS gene polymorphisms significantly increased risk of obesity among Malay children (sex- and age-adjusted
OR=1.580; 95%CI: 1.134-2.201). However, INSR gene polymorphisms were not significantly associated with childhood obesity. In conclusion, the polymorphisms of INS gene, rather than INSR gene, were associated with childhood obesity in the Malay population.

Matched MeSH terms: Body Weight
Fulltext Association between ready-to-eat cereal consumption and anthropometric status among primary school children in Kuala Lumpur, Malaysia

Koo, H.C., Suriyani, M.Y., Ruzita, A.T.

Malays J Nutr, 2014;20(3):367-375.
MyJurnal

Introduction: The consumption of ready-to-eat cereals (RTECs) has been associated with lower anthropometric status as well as a lower risk of childhood obesity. This relationship has not been investigated among school children in Malaysia. This study aimed to determine the association between consumption of RTECs and anthropometric status among primary school children in Kuala Lumpur. Method: In this cross-sectional study, a total of 208 school children aged 10 and 11 years were recruited from Kuala Lumpur, Malaysia. Information on socio-demographics, RTECs consumption and anthropometric measurements (height, weight and waist circumference) were obtained. Results: The overall median body mass index (BMI) and waist circumference (WC) were 17.95(IqR 6.45) kg/m2 and 57.35 (IqR 13.00) cm, respectively. The majority of the children (73%) consumed RTECs. The prevalence of obesity was 23.1%, with more boys (31%) than girls (17.4%) being obese. Meanwhile, 16.8% of the children were overweight. BMI (U=3335.50, z=-2.278, p=0.023) and WC (U=3273.50, z=-2.440, p=0.015) of those who consumed RTECs were significantly lower than those who did not consume RTECs. Meanwhile, children who did not consume RTECs were significantly more likely to develop abdominal adiposity than those who consumed RTECS, X2(2, N=208) =7.61, p=0.022. Conclusion: Children who consumed RTECs have significantly lower BMI and WC, as well as a lower chance of developing abdominal adiposity. Consumption of RTECs indicates an overall healthy lifestyle with an excellent nutritional profile to promote healthy body weight in children and decreased risk of childhood obesity.

Matched MeSH terms: Body Weight
Fulltext Association between socioeconomic status and obesity among 12-year-old Malaysian adolescents

Ahmad A, Zulaily N, Shahril MR, Syed Abdullah EFH, Ahmed A

PLoS One, 2018;13(7):e0200577.
PMID: 30044842 DOI: 10.1371/journal.pone.0200577

The epidemic of obesity in developed countries is commonly associated with poor dietary habit and sedentary lifestyle. However, other determinants, including education background and family income, may contribute towards the problem especially in developing countries. This study aimed to determine the influence of socioeconomic status (SES) on obesity among 12-year-old school adolescents in Terengganu, Malaysia. Body weight and height were measured and BMI was categorised based on WHO z-score cut-off points. Information was obtained from self-reported questionnaire on parents' education background, family income and occupation. A total of 3,798 school adolescents aged 12 years (44% boys and 56% girls) were recruited. There was no significant difference in BMI status between boys and girls, or between rural and urban participants. There were significant differences between BMI categories and gender, household income and SES level within rural areas. In the urban areas, significant differences were found between BMI categories and gender, parents' occupational and educational level, household income and size, and SES level. A logistic regression model found several SES factors to be predictors of obesity in this population, namely, gender, household size, father's occupation level, household income level and SES level. Each component of SES has been significantly associated with the BMI category of school adolescents, particularly in the urban areas. This suggests the requirement of multifaceted approaches, including the role of family, society and authorities, in the effort to curtail adolescent obesity.

Matched MeSH terms: Body Weight
Fulltext Association between the school environment and children's body mass index in Terengganu: A cross sectional study

Wafa SW, Ghazalli R

PLoS One, 2020;15(4):e0232000.
PMID: 32330177 DOI: 10.1371/journal.pone.0232000

With the on-going interest in implementing school policies to address the problem of childhood obesity in Malaysia, there is urgent need for information about the association between school environment and children's weight status. This study aims to investigate the association between school environmental factors (physical, economic, political and sociocultural) with BMI of school children in Terengganu. The school environment factors were assessed using a set of validated whole-school environmental mapping questionnaires, consisting of 76 criteria with four domains; physical environment (41 criteria), economic environment (nine criteria), political environment (nine criteria) and sociocultural environment (17 criteria). This involved face-to-face interview sessions with 32 teachers from 16 schools (eight rural and eight urban). In addition, 400 school children aged between 9 and 11 years of the selected schools were assessed for BMI (WHO 2007 reference chart), dietary intake (food frequency questionnaire (FFQ)) and physical activity level (physical activity questionnaire for children (PAQ-C)). Multiple regression was used to examine the association between school environment factors and BMI of the school children. Seven school environment criteria were found to be associated with BMI of school children when it was adjusted for calorie intake and physical activity level. About 33.4% of the variation in BMI of school children was explained by health professional involvement, simple exercise before class, encouragement to walk/ride bicycle to/from school, no high-calorie food sold, healthy options of foods and drinks at tuck shop, availability of policy on physical activity and training teacher as a role model. Policy makers should make urgent actions to address the obesogenic features of school environments. It should strive towards setting up healthy school environment and improving school curricula to promote healthy behaviours among the school children.

Matched MeSH terms: Body Weight

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