Displaying publications 101 - 120 of 3950 in total

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  1. Zaini Hamzah, Che Yasmin Amirudin, Seh Datul Riduan, Ahmad Saat
    MyJurnal
    137 Cs is well known man-made radionuclide produced from nuclear industry. Nuclear weapon tests and nuclear accidents had contributed to presence of 137 Cs into the worldwide environment including Malaysia. It has spread out to the entire world through the air and water current. Since Cameron Highlands is located at high altitude, there is a better chance of the 137 Cs to settle down on the trees and later the soil underneath. In this study, the soil samples were taken at the slopes of two different tea plantation areas namely A and B. The soil samples were oven dried, ground, sieved and packed and sealed properly in plastic containers before measurement. Each plastic container contains around 450 g of sample. The measurement of 137 Cs activity concentration was done using HPGe detector gamma spectrometer. The spectrum was analyzed using Gamma Vision software to calculate the activity concentration of 137 Cs with energy peak of 661.66 keV. The activity concentration of 137 Cs found in the samples ranged from 0.23 to 1.90 and 0.11 to 3.01 Bq/kg for tea plantation A and tea plantation B, respectively. From the activity concentration of 137 Cs result, it was comparable to the others research regarding to 137 Cs in the soil around Asian.
    Matched MeSH terms: Water
  2. Zaini Hamzah, Masitah Alias, Ahmad Saat, Abdul Kadir Ishak
    MyJurnal
    The issue of water quality is a never ended issue and becoming more critical when considering the presence of natural radionuclides. Physical parameters and the levels of radionuclides may have some correlation and need further attention. In this study, the former tin mine lake in Kampong Gajah was chosen as a study area for its past historical background which might contribute to attenuation of the levels of natural radionuclides in water. The water samples were collected from different lakes using water sampler and some in-situ measurement were conducted to measure physical parameters as well as surface dose level. The water samples were analyzed for its gross alpha and gross beta activity concentrations using liquid scintillation counting and in-house cocktail method. Gross alpha and beta analyzed using in-house cocktail are in the range of 3.17 to 8.20 Bq/L and 9.89 to 22.20 Bq/L; 1.64 to 8.78 Bq/L and 0.22 to 28.22 Bq/L, respectively for preserved and un-preserved sample. The surface dose rate measured using survey meter is in the range of 0.07 to 0.21 μSv/h and 0.07 to 0.2 μSv/h for surface and 1 meter above the surface of the water, respectively.
    Matched MeSH terms: Water; Water Pollutants, Radioactive; Water Quality
  3. Zaini Hamzah, Wan Noorhayani Wan Rosdi, Abdul Khalik Wood
    MyJurnal
    Well water is a renewable natural resources and one of the drinking water sources. The well water may constituted of dissolved essential chemicals such as K+, Ca''+ and Na+ ; and natural radionuclides such as radioisotopes from uranium-thorium decay series. The geology and mineral composition of the soil will determined the kinds and levels of chemical contents in the groundwater resources. The water flows through the geological formation and dissolved the chemicals before reaching the aquifers. To evaluate how much chemicals and natural radioactive in the water resources, a study has been carried out. Well water samples in this study were taken from 3 districts in Kelantan, which is Bachok, Machang and Kuala Krai. Similarly, in situ water quality parameters were measured using YSI portable water quality parameter include pH, salinity, dissolve oxygen(DO), conductivity, turbidity and total dissolved solids(TDS). The concentrations of K', Ca" and Na' were determined using Energy Dispersive X-ray Fluorescence (EDXRF). Five ml of filtered sample was pipette into the sample cup and, irradiated and measured for 100 seconds counting times. The type of filter used for measuring If+ and Cat{ was Al-thin and default for Nat The ranged of concentration of Kt Ce and Na+ is 23.04-251.89, 3.12-.45.41, and 3.71-125.75 ppm, respectively.
    Matched MeSH terms: Water Quality; Drinking Water; Water Wells; Water Resources
  4. Zaini HBM, Sintang MDB, Pindi W
    Food Sci Nutr, 2020 Oct;8(10):5497-5507.
    PMID: 33133552 DOI: 10.1002/fsn3.1847
    Chicken sausages included with three different quantities of banana (Musa balbisiana) peel powder. The technological properties (cooking yield, texture, water-holding capacity, color, rheology, and texture), composition, and sensory acceptability were assessed. In storage study, lipid oxidation of the best formulation from the sensory score was evaluated. The inclusion of banana peel powder (BPP) raises the nutritional value with regard to an increase in dietary fiber and a reduction in the sausage fat content. The addition of BPP also causes a significant increase in the cooking yield and water-holding capacity. Additionally, storage modulus values increase with the increase in the BPP's concentration. However, with BPP incorporation, a hard texture and darkening of the sausage were observed. Interestingly, our findings exhibit the compromise in microstructural of chicken sausage with high percentage of BPP manifested by the high storage modulus and hardness but with low resistance toward stress, short linear viscoelastic region. This aspect also caused a significant change in the sensory score. The TBA value in the sausage containing 2% BPP exhibited a delay in lipid oxidation up to 55%, prompting its antioxidant potential. Generally, the incorporation of BPP to chicken sausage changes its properties. BPP has been a potential candidate as a value-adding ingredient that may be used during meat preparation since it positively influences the nutritional value and specific technological properties of the food.
    Matched MeSH terms: Water
  5. Zainal-Abidin MH, Hayyan M, Ngoh GC, Wong WF
    ACS Omega, 2020 Jan 28;5(3):1656-1668.
    PMID: 32010840 DOI: 10.1021/acsomega.9b03709
    The application of graphene in the field of drug delivery has attracted massive interest among researchers. However, the high toxicity of graphene has been a drawback for its use in drug delivery. Therefore, to enhance the biocompatibility of graphene, a new route was developed using ternary natural deep eutectic solvents (DESs) as functionalizing agents, which have the capability to incorporate various functional groups and surface modifications. Physicochemical characterization analyses, including field emission scanning electron microscope, fourier-transform infrared spectroscopy, Raman spectroscopy, Brunauer-Emmett-Teller, X-ray diffraction, and energy dispersive X-ray, were used to verify the surface modifications introduced by the functionalization process. Doxorubicin was loaded onto the DES-functionalized graphene. The results exhibited significantly improved drug entrapment efficiency (EE) and drug loading capacity (DLC) compared with pristine graphene and oxidized graphene. Compared with unfunctionalized graphene, functionalization with DES choline chloride (ChCl):sucrose:water (4:1:4) resulted in the highest drug loading capacity (EE of 51.84% and DLC of 25.92%) followed by DES ChCl:glycerol:water (1:2:1) (EE of 51.04% and DLC of 25.52%). Following doxorubicin loading, graphene damaged human breast cancer cell line (MCF-7) through the generation of intracellular reactive oxygen species (>95%) and cell cycle disruption by increase in the cell population at S phase and G2/M phase. Thus, DESs represent promising green functionalizing agents for nanodrug carriers. To the best of our knowledge, this is the first time that DES-functionalized graphene has been used as a nanocarrier for doxorubicin, illustrating the potential application of DESs as functionalizing agents in drug delivery systems.
    Matched MeSH terms: Water
  6. Zainal-Abideen M, Aris A, Yusof F, Abdul-Majid Z, Selamat A, Omar SI
    Water Sci Technol, 2012;65(3):496-503.
    PMID: 22258681 DOI: 10.2166/wst.2012.561
    In this study of coagulation operation, a comparison was made between the optimum jar test values for pH, coagulant and coagulant aid obtained from traditional methods (an adjusted one-factor-at-a-time (OFAT) method) and with central composite design (the standard design of response surface methodology (RSM)). Alum (coagulant) and polymer (coagulant aid) were used to treat a water source with very low pH and high aluminium concentration at Sri-Gading water treatment plant (WTP) Malaysia. The optimum conditions for these factors were chosen when the final turbidity, pH after coagulation and residual aluminium were within 0-5 NTU, 6.5-7.5 and 0-0.20 mg/l respectively. Traditional and RSM jar tests were conducted to find their respective optimum coagulation conditions. It was observed that the optimum dose for alum obtained through the traditional method was 12 mg/l, while the value for polymer was set constant at 0.020 mg/l. Through RSM optimization, the optimum dose for alum was 7 mg/l and for polymer was 0.004 mg/l. Optimum pH for the coagulation operation obtained through traditional methods and RSM was 7.6. The final turbidity, pH after coagulation and residual aluminium recorded were all within acceptable limits. The RSM method was demonstrated to be an appropriate approach for the optimization and was validated by a further test.
    Matched MeSH terms: Water/chemistry*; Water Supply/standards*; Water Purification/methods*
  7. Zainal Z, Hui LK, Hussein MZ, Abdullah AH, Hamadneh IM
    J Hazard Mater, 2009 May 15;164(1):138-45.
    PMID: 18809254 DOI: 10.1016/j.jhazmat.2008.07.154
    In this paper, the newly explored TiO(2)-Chitosan/Glass was suggested as a promising alternative material to conventional means of wastewater treatment. Characterization of TiO(2)-Chitosan/Glass photocatalyst was studied with SEM-EDX, XRD, and Fourier transform infrared spectroscopy (FTIR) analysis. The combination effect of photodegradation-adsorption process for the removal of methyl orange (MO), an acid dye of the monoazo series occur promisingly when four layers of TiO(2)-Chitosan/Glass photocatalyst was used for MO removal. Approximately, 87.0% of total MO removal was achieved. The reactive -NH(2), -OH, and metal oxide contents in the prepared photocatalyst responsible for the photodegradation-adsorption effect were confirmed by FTIR study. Similarly, MO removal behavior was well supported by SEM-EDX and XRD analysis. Significant dependence of MO removal on the TiO(2)-Chitosan loading can be explained in terms of relationship between quantum yield of photocatalytic reactions and photocatalyst structure/activity. Hence, the research work done thus far suggests a new method, having both the advantages of photodegradation-adsorption process in the abatement of various wastewater pollutants.
    Matched MeSH terms: Water Purification/methods*
  8. Zainal Z, Lee CY, Hussein MZ, Kassim A, Yusof NA
    J Hazard Mater, 2007 Jul 19;146(1-2):73-80.
    PMID: 17196740
    Mixed dye consists of six commercial dyes and textile effluents from cotton dyeing process were treated by electrochemical-assisted photodegradation under halogen lamp illumination. Two types of effluents were collected which are samples before and after undergone pre-treatment at the factory wastewater treatment plant. The photodegradation process was studied by evaluating the changes in concentration employing UV-vis spectrophotometer (UV-vis) and total organic carbon (TOC) analysis. The photoelectrochemical degradation of mixed dye was found to follow the Langmuir Hinshelwood pseudo-first order kinetic while pseudo-second order kinetic model for effluents by using TOC analyses. The chemical oxygen demand (COD) and biochemical oxygen demand (BOD) values of mixed dye and raw effluents were reported. Photoelectrochemical characteristic of pollutants was studied using the cyclic voltammetry technique. Raw effluent was found to exhibit stronger reduction behaviour at cathodic bias potential but slightly less photoresponse at anodic bias than mixed dye.
    Matched MeSH terms: Water Pollutants, Chemical/radiation effects*; Water Pollutants, Chemical/chemistry*; Water Purification/methods
  9. Zainal Z, Lee CY, Hussein MZ, Kassim A, Yusof NA
    J Hazard Mater, 2005 Feb 14;118(1-3):197-203.
    PMID: 15721544
    Electrochemical-assisted photodegradation of methyl orange has been investigated using TiO2 thin films. The films were prepared by sol-gel dip-coating method. Several operational parameters to achieve optimum efficiency of this electrochemical-assisted photodegradation system have been tested. Photoelectrochemical degradation was studied using different light sources and light intensity. The light sources chosen ranged from ultraviolet to visible light. The effect of agitation of the solution at different speeds has also been studied. Slight improvement of photodegradation rate was observed by applying higher agitation speed. Investigation on the electrode after repeated usages show the electrode can be reused up to 20 times with percentage of deficiency less than 15%. The study on the effect of solution temperature indicated that the activation energy of the methyl orange degradation is 18.63 kJ mol(-1).
    Matched MeSH terms: Water Movements; Water Purification/methods*
  10. Zainal Z, Hui LK, Hussein MZ, Taufiq-Yap YH, Abdullah AH, Ramli I
    J Hazard Mater, 2005 Oct 17;125(1-3):113-20.
    PMID: 15996813
    The photodegradation of various dyes in aqueous solution was studied. Experiments were carried out using glass coated titanium dioxide thin film as photocatalyst. Photodegradation processes of methylene blue (MB), methyl orange (MO), indigo carmine (IC), chicago sky blue 6B (CSB), and mixed dye (MD, mixture of the four mentioned single dye) were reported. As each photodegradation system is pH dependent, the photodegradation experiment was carried out in each dye photodegradation reactive pH range at approximately 28 degrees C. The dyes removal efficiency was studied and compared using UV-vis spectrophotometer analysis. The total removal of each dye was: methylene blue (90.3%), methyl orange (98.5%), indigo carmine (92.4%), chicago sky blue 6B (60.3%), and mixed dyes (70.1%), respectively. The characteristic of the photocatalyst was investigated using X-ray diffractometer (XRD). The amount of each dye intermediate produced in the photodegradation process was also determined with the help of total organic carbon (TOC) analysis.
    Matched MeSH terms: Water/chemistry*; Water Pollutants, Chemical/isolation & purification*; Water Pollution, Chemical/prevention & control*
  11. Zainal N, Azimah E, Hassan Z, Abu Hassan H, Hashim M
    Sains Malaysiana, 2014;43:1557-1564.
    In this work, the emission efficiency of InxGa1-xN based light emitting diodes (LEDs) had been numerically investigated with the variation of the number of quantum well. From our calculation, we found that non-uniformity of carriers distribution (especially electron) in the wells leads to serious inhomogeneity of radiative recombination distribution that would degrade the efficiency of the LED with more wells. However, the problem was minimized when the selected quantum barriers were doped with a reasonable doping level. Comparison with other reported experimental works were also included. At the end of this work, we proposed several types of preferable LEDs designs with optimum structural parameters.
    Matched MeSH terms: Water Wells
  12. Zainal H, Jamil A, Md Nor N, Tang MM
    Skin Res Technol, 2020 Jan;26(1):91-98.
    PMID: 31535769 DOI: 10.1111/srt.12768
    BACKGROUND: Defective skin's acidic mantle is a component of atopic dermatitis (AD) pathophysiology. We mapped the skin pH and determine its relationship with transepidermal water loss (TEWL), hydration and disease severity.

    MATERIALS AND METHODS: A cross-sectional study involving patients aged ≥18 years. Eczema Area and Severity Index (EASI) was assessed. Skin pH, TEWL and hydration were measured at 18 pre-determined sites.

    RESULTS: Forty-eight patients participated, 33(68.8%) females and 15(31.3%) males aged 28.46 ± 12.07 years. The overall skin pH was 5.32 ± 0.68 ranging from 5.16 ± 0.75 to 5.52 ± 0.59. The lowest pH 5.16 ± 0.75 was at anterior leg, popliteal fossae 5.18 ± 0.67, lower back 5.21 ± 0.64, forehead 5.22 ± 0.62, upper back 5.25 ± 0.65 and neck 5.26 ± 0.76. Highest pH was at the cheek 5.52 ± 0.59, anterior thigh 5.47 ± 0.68, dorsal arm 5.46 ± 0.68, volar arm 5.43 ± 0.67 and abdomen 5.39 ± 0.67. Lesional areas' pH (5.40 ± 0.13) was higher than nonlesional (5.27 ± 0.14), P = .01. pH at AD predilection sites was significantly lower non-predilection sites (5.26 ± 0.59 vs 5.34 ± 0.64). pH did not correlate with TEWL (r = .23, P = .12), EASI (r = .19, P = .20) and itch (r = .06, P = .70) but correlated with hydration r = -.33, P = .02.

    CONCLUSION: Skin pH was lower at AD predilection sites. There was no correlation between pH with AD severity and TEWL, pH correlated with hydration.

    Matched MeSH terms: Water Loss, Insensible/physiology*
  13. Zainal Abidin, M., Shamsudin, R., Othman, Z., Abdul Rahman, R.
    MyJurnal
    Cantaloupes continue to ripen after harvesting which is caused by ethylene production due to climacteric behaviour during postharvest storage. In this study, the cantaloupe fruits harvested at commercial maturity were evaluated for quality attributes during three weeks of storage at 10°C and a relative humidity (RH) of 90±5%. In addition, fresh-cut samples were stored for a further 19 days at 2°C and 87% RH. The fresh-cut samples were prepared on a weekly basis by dipping into deionised water (control) at 2°C for 1 minute. The effect of postharvest storage of cantaloupe on the physico-chemical properties and microbial activity was observed prior to fresh-cut processing. It was found that firmness, luminosity (L*), and titratable acidity (TA) decreased, while total soluble solids (TSS), pH, TSS:TA ratio, microbial activity (total plate count (TPC) and yeast and mould (YM)) of the fresh-cut increased over the postharvest storage period of the fruit. Meanwhile, the orange colour and the intensity (hue angle, hab, and chromaticity) of the flesh did not differ significantly during storage. The cantaloupe stored for three weeks at a low temperature indicated a successful potential for fresh-cut processing due to good maintenance of the product quality.
    Matched MeSH terms: Water
  14. Zainal Abidin MH, Abd Halim KB, Huyop F, Tengku Abdul Hamid TH, Abdul Wahab R, Abdul Hamid AA
    J Mol Graph Model, 2019 07;90:219-225.
    PMID: 31103914 DOI: 10.1016/j.jmgm.2019.05.003
    Dehalogenase E (DehE) is a non-stereospecific enzyme produced by the soil bacterium, Rhizobium sp. RC1. Till now, the catalytic mechanism of DehE remains unclear although several literature concerning its structure and function are available. Since DehE is non-stereospecific, the enzyme was hypothesized to follow a 'direct attack mechanism' for the catalytic breakdown of a haloacid. For a molecular insight, the DehE modelled structure was docked in silico with the substrate 2-chloropropionic acid (2CP) in the active site. The ideal position of DehE residues that allowed a direct attack mechanism was then assessed via molecular dynamics (MD) simulation. It was revealed that the essential catalytic water was hydrogen bonded to the 'water-bearer', Asn114, at a relatively constant distance of ∼2.0 Å after 50 ns. The same water molecule was also closely sited to the catalytic Asp189 at an average distance of ∼2.0 Å, signifying the imperative role of the latter to initiate proton abstraction for water activation. This reaction was crucial to promote a direct attack on the α-carbon of 2CP to eject the halide ion. The water molecule was oriented favourably towards the α-carbon of 2CP at an angle of ∼75°, mirrored by the formation of stable enzyme-substrate orientations throughout the simulation. The data therefore substantiated that the degradation of a haloacid by DehE followed a 'direct attack mechanism'. Hence, this study offers valuable information into future advancements in the engineering of haloacid dehalogenases with improved activity and selectivity, as well as functionality in solvents other than water.
    Matched MeSH terms: Water/metabolism
  15. Zainab Ngaini, Rafeah Wahi, Dayang Halimatulzahara, Nur An-Nisaa’ Mohd Yusoff
    MyJurnal
    Oil pollution remains a serious concern especially in Malaysia. Many strategies have been employed to overcome oil pollution. In this research, sago waste material abundantly found in Sarawak was used and chemically modified into an oil adsorbent . Sago waste cellulosic residues were modified using fatty acid derivatives. The capability of the chemically modified sago waste to absorb oil from aqueous solution was studied and compared with the untreated sago waste. The modified sago waste showed higher hydrophobicity than the untreated sago waste, implying that it is less affinity for water and also an excellent affinity for oil. This chemically modified sago waste would be the most suitable for applications where engine oil (i.e., Shell Helix HX5) is to be removed from an aqueous environment. The modified sago waste selectively absorbs the oil and remains on the surface and is to be removed when the application is complete.
    Matched MeSH terms: Water
  16. Zain S, Roslani N, Hashim R, Anuar N, Suja F, Basri N, et al.
    Fossil fuels (petroleum, natural gas and coal) are the main resources for generating electricity. However, they have been major contributors to environmental problems. One potential alternative to explore is the use of microbial fuel cells (MFCs), which generate electricity using microorganisms. MFCs uses catalytic reactions activated by microorganisms to convert energy preserved in the chemical bonds between organic molecules into electrical energy. MFC has the ability to generate electricity during the wastewater treatment process while simultaneously treating the pollutants. This study investigated the potential of using different types of mixed cultures (raw sewage, mixed liquor from the aeration tank & return waste activated sludge) from an activated sludge treatment plant in MFCs for electricity generation and pollutant removals (COD & total kjeldahl nitrogen, TKN). The MFC in this study was designed as a dual-chambered system, in which the chambers were separated by a NafionTM membrane using a mixed culture of wastewater as a biocatalyst. The maximum power density generated using activated sludge was 9.053 mW/cm2, with 26.8% COD removal and 40% TKN removal. It is demonstrated that MFC offers great potential to optimize power generation using mixed cultures of wastewater.
    Matched MeSH terms: Waste Water
  17. Zain NN, Abu Bakar NK, Mohamad S, Saleh NM
    PMID: 24161875 DOI: 10.1016/j.saa.2013.09.129
    A greener method based on cloud point extraction was developed for removing phenol species including 2,4-dichlorophenol (2,4-DCP), 2,4,6-trichlorophenol (2,4,6-TCP) and 4-nitrophenol (4-NP) in water samples by using the UV-Vis spectrophotometric method. The non-ionic surfactant DC193C was chosen as an extraction solvent due to its low water content in a surfactant rich phase and it is well-known as an environmentally-friendly solvent. The parameters affecting the extraction efficiency such as pH, temperature and incubation time, concentration of surfactant and salt, amount of surfactant and water content were evaluated and optimized. The proposed method was successfully applied for removing phenol species in real water samples.
    Matched MeSH terms: Water/analysis; Water Pollutants, Chemical/isolation & purification*; Water Purification/methods*
  18. Zain NA, Ismail MR, Mahmood M, Puteh A, Ibrahim MH
    Molecules, 2014;19(2):1795-819.
    PMID: 24504074 DOI: 10.3390/molecules19021795
    The use of periodical water stress and potassium fertilization may enhance rice tolerance to drought stress and improve the crop's instantaneous water use efficiency without much yield reduction. This study was conducted to assess the effects of different periodical water stress combined with potassium fertilization regimes on growth, yield, leaf gas exchanges and biochemical changes in rice grown in pots and compare them with standard local rice grower practices. Five treatments including (1) standard local grower's practice (control, 80CF = 80 kg K2O/ha + control flooding); (2) 120PW15 = 120 kg K2O/ha + periodical water stress for 15 days; (3) 120DS15V = 120 kg K2O/ha + drought stress for 15 days during the vegetative stage; (4) 120DS25V = 120 kg K2O/ha + drought stress for 25 days and (5) 120DS15R = 120 kg K2O/ha + drought stress for 15 days during the reproductive stage, were evaluated in this experiment. Control and 120PW15 treatments were stopped at 100 DAS, and continuously saturated conditions were applied until harvest. It was found that rice under 120PW15 treatment showed tolerance to drought stress evidenced by increased water use efficiency, peroxidase (POX), catalase (CAT) and proline levels, maximum efficiency of photosystem II (fv/fm) and lower minimal fluorescence (fo), compared to other treatments. Path coefficient analysis revealed that most of parameters contribute directly rather than indirectly to rice yield. In this experiment, there were four factors that are directly involved with rice yield: grain soluble sugar, photosynthesis, water use efficiency and total chlorophyll content. The residual factors affecting rice yield are observed to be quite low in the experiment (0.350), confirming that rice yield was mostly influenced by the parameters measured during the study.
    Matched MeSH terms: Water/metabolism*
  19. Zain MA, Pandy V, Majeed ABA, Wong WF, Mohamed Z
    Exp Anim, 2019 Feb 26;68(1):113-124.
    PMID: 30393276 DOI: 10.1538/expanim.18-0078
    Chronic stress has been associated with impairment of memory, learning, and social cognition. In animal studies, chronic stress has been shown to impair rodent sociability behaviour which mimics social withdrawal as observed in depression patients. The effect of chronic stress on social recognition, however, is uncertain. Moreover, with reference to spatial learning and memory, the effect of chronic stress is dependent on the type of behavioural task: an appetitively or aversively motivated tasks. The effect of chronic stress was consistent in impairing spatial learning and memory in the appetitive task; however, the effect was inconsistent in an aversive task like the Morris water maze. Thus, we aimed to investigate the effect of chronic restraint stress on sociability and social recognition by using a modified protocol of the three-chamber paradigm and the effect of chronic restraint stress on spatial learning and memory by using the Morris water maze test in young adult C57BL/6J male mice. The present report also describes a modified protocol of the three-chamber paradigm. Our modification is based on measurement of sniffing behaviour, which is a direct social interaction that represents sociability. We used the chronic restraint stress paradigm for 6 h/day for 21 days to induce depression-like symptoms in male C57BL/6J mice which were validated by forced-swim test. We observed that the stressed group had impairments in their sociability behaviour but that social recognition was not affected. Furthermore, we confirmed that chronic stress produced no significant impairment in spatial learning and memory of the mice in the water maze.
    Matched MeSH terms: Water
  20. Zailina H, Najibah H, Aiezzati AN, Praveena SM, Patimah I
    Biomed Res Int, 2014;2014:797603.
    PMID: 25530970 DOI: 10.1155/2014/797603
    A cross-sectional study was carried out to determine the arsenic (As) and cadmium (Cd) concentrations in blood, urine, and drinking water as well as the health implications on 100 residents in an urban and a rural community. Results showed the blood As, urinary Cd, DNA damage, and water As and Cs were significantly (P < 0.001) higher in the rural community. Findings showed significant (P < 0.005) correlations between blood As and DNA damage with household income, years of residence, and total glasses of daily water consumption among the rural residents. The urinary NAG concentrations, years of residence, milk powder intake (glass/week), and seafood intake (per week) were significantly correlated (P < 0.005) with urinary Cd concentrations among respondents. In addition, urinary Cd level significantly influenced the urinary NAG concentrations (P < 0.001). The rural respondents experienced significantly higher lymphocyte DNA damage and blood As influenced by their years of residence and water consumption. The Cd in drinking water also resulted in the rural respondents having significantly higher urinary NAG which had a significant relationship with urinary Cd.
    Matched MeSH terms: Drinking Water/chemistry*
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