MyMedR

Fulltext Prevalence of drug-related emergency department visits at a teaching hospital in Malaysia

Jatau AI, Aung MM, Kamauzaman TH, Rahman AF

Drugs Real World Outcomes, 2015 10 23;2(4):387-395.

PMID: 26689834 DOI: 10.1007/s40801-015-0045-2

BACKGROUND: Data on the prevalence of adverse drug event (ADE)-related emergency department (ED) visits in developing countries are limited. Malaysia is located in South-East Asia, and, to our knowledge, no information exists on ADE-related ED visits.

OBJECTIVE: The objective of this study was to determine the prevalence, preventability, severity, and outcome of drug-related ED visits.

METHODOLOGY: A cross-sectional study was conducted in consenting patients who visited the ED of Hospital Universiti Sains Malaysia over a 6-week period. The ED physician on duty determined whether or not the visit was drug related according to set criteria. Other relevant information was extracted from the patient's medical folder by a clinical pharmacist.

RESULTS: Of the 434 consenting patients, 133 (30.6 %; 95 % confidence interval [CI] 26-35 %) visits were determined to be ADE related; 55.5 % were considered preventable, 11.3 % possibly preventable, and 33.1 % not preventable. Severity was classed as mild in 1.5 %, moderate in 67.7 %, and severe in 30.8 %. The most common ADEs reported were drug therapeutic failure (55.6 %) and adverse drug reactions (32.3 %). The most frequently implicated drugs were antidiabetics (n = 31; 23.3 %), antihypertensives (n = 28; 21.1 %), antibiotics (n = 13; 9.8 %), and anti-asthmatics (n = 11; 8.3 %). A total of 93 patients (69.9 %) were admitted to the ED for observation, 25 (18.8 %) were discharged immediately after consultation, and 15 (11.3 %) were admitted to the ward through the ED.

CONCLUSION: The prevalence of ADE-related ED visits was high; more than one-half of the events were considered preventable and one-third was classed as severe. As such, preventive measures will minimize future occurrences and increase patient safety.

Matched MeSH terms: Prevalence*

Fulltext Awareness of eye complications and prevalence of retinopathy in the first visit to eye clinic among type 2 diabetic patients

Tajunisah I, Wong P, Tan L, Rokiah P, Reddy S

Int J Ophthalmol, 2011;4(5):519-24.

PMID: 22553714 DOI: 10.3980/j.issn.2222-3959.2011.05.12

AIM: To assess the awareness of eye complications and the prevalence of retinopathy, in the first visit to eye clinic, among type 2 diabetic patients attending a tertiary medical centre in Kuala Lumpur, Malaysia.
METHODS: An investigator-administered questionnaire was given to 137 patients with diabetes undergoing first time eye screening in the eye clinic. This was followed by a detailed fundus examination by a senior ophthalmologist to assess for presence of retinopathy.
RESULTS: Almost 86% of respondents were aware of diabetic eye complications, especially in patients who had achieved tertiary educational level (96.3%). The majority of the patients (78.8%) were referred by their physicians and only 20.4% came on their own initiative. Many of the patients (43.8%) did not know how frequent they should go for an eye check-up and 72.3% did not know what treatments were available. Lack of understanding on diabetic eye diseases (68.6%) was the main barrier for most patients for not coming for eye screening earlier. Despite a high level of awareness, only 21.9% had recorded HbA1c level of <6.5% while 31.4% were under the erroneous assumption of having a good blood sugar control. A total of 29.2% had diabetic retinopathy in their first visit eye testing.
CONCLUSION: In the present study, 29.2% of type 2 diabetic patients had retinopathy in their first time eye testing. Although the awareness of diabetic eye complications was high among first time eye screening patients, the appropriate eye care-seeking behavior was comparatively less and should be rectified to prevent the rise of this sight threatening eye disease.
KEYWORDS: awa-reness; diabetic retinopathy; eye complications; eye screening
Study site: Eye clinic, University Malaya Medical Centre (UMMC), Kuala Lumpur, Malaysia

Matched MeSH terms: Prevalence*

Fulltext A review of dengue research in Malaysia

Cheah WK, Ng KS, Marzilawati AR, Lum LC

Med J Malaysia, 2014 Aug;69 Suppl A:59-67.

PMID: 25417953 MyJurnal

Dengue infection is a major cause of morbidity and mortality in Malaysia. To date, much research on dengue infection conducted in Malaysia have been published. One hundred and sixty six articles related to dengue in Malaysia were found from a search through a database dedicated to indexing all original data relevant to medicine published between the years 2000-2013. Ninety articles with clinical relevance and future research implications were selected and reviewed. These papers showed evidence of an exponential increase in the disease epidemic and a varying pattern of prevalent dengue serotypes at different times. The early febrile phase of dengue infection consist of an undifferentiated fever. Clinical suspicion and ability to identify patients at risk of severe dengue infection is important. Treatment of dengue infection involves judicious use of volume expander and supportive care. Potential future research areas are discussed to narrow our current knowledge gaps on dengue infection.

Matched MeSH terms: Prevalence

Fulltext Identification of genotypes of Influenza A virus in Malaysia

Mm R, Kk W, I I, Zz R, H A

Pak J Med Sci, 2014 Sep;30(5):1068-71.

PMID: 25225528 DOI: 10.12669/pjms.305.5224

Influenza is considered as an emerging disease until today. The present study was undertaken to determine the prevalent genotypes of Influenza A virus in Malaysia.

Matched MeSH terms: Prevalence

Fulltext Noise-induced hearing loss among quarry workers in a north-eastern state of malaysia: a study on knowledge, attitude and practice

Ismail AF, Daud A, Ismail Z, Abdullah B

Oman Med J, 2013 Sep;28(5):331-6.

PMID: 24044059 DOI: 10.5001/omj.2013.96

Noise is known to be one of the environmental and occupational hazards listed in the Factory and Machinery Act 1967. Quarries with loud deafening sounds from trucks and machineries pose the risk of noise-induced hearing loss to workers. This study was designed to assess the knowledge, attitude and practice towards noise-induced hearing loss and to determine the prevalence of noise-induced hearing loss and its associated factors among quarry workers in a north-eastern state of Malaysia.

Matched MeSH terms: Prevalence

Fulltext Acute coronary syndrome in women of reproductive age

Idris N, Aznal SS, Chin SP, Wan Ahmad WA, Rosman A, Jeyaindran S, et al.

Int J Womens Health, 2011;3:375-80.

PMID: 22140324 DOI: 10.2147/IJWH.S15825

There is scarce or no data on prevalence and presentation of acute coronary syndrome (ACS) among women of reproductive age. Furthermore, whether women of reproductive age presenting with ACS have the same risk factors as men and older women is not known.

Matched MeSH terms: Prevalence

Fulltext Prevalence of chronic illness and health seeking behaviour in Malaysian Population: Results from the Third National Health Morbidity Survey (NHMS III) 2006

Amal NM, Paramesarvathy R, Tee GH, Gurpreet K, Karuthan C

Med J Malaysia, 2011 Mar;66(1):36-41.

PMID: 23765141 MyJurnal

The third National Health Morbidity Survey was conducted in 2006 on a nationally representative sample of population in Malaysia in order to obtain community-based data and information on the prevalence of chronic illness. Of 57,500 eligible respondents 56710 (98.6%) participated in the study. Estimated overall prevalence of chronic illness in the Malaysian population within a recall period of one year was 15.5% (95% CI 15.1% - 15.9%). Chronic illness was reported significantly higher among the females, 16.8% (16.3 - 17.3). The most common chronic illness was hypertension (7.9%, 7.6 - 8.2), followed by diabetes mellitus (4.0%, 3.8 - 4.2) and highest reported by the Indians (19.7%, 18.4 - 21.0). Among the respondents who had sought treatment for chronic illness from government health facilities, Malays (65.8%) and those with monthly household income of less than RM400 (76.6%) were the highest. Chinese (44.5%) and those with household income of RM5000 and above (54.3%) were the highest groups who sought treatment from the private health facilities. Most of the respondents reported mild illness was the main reason for not seeking treatment for their chronic illness. It is hoped that the results of this survey will help the Ministry of Health Malaysia to enhance health programmes and planning resource allocation in order to improve health status of the population.
Study name: National Health and Morbidity Survey (NHMS-2006)

Matched MeSH terms: Prevalence

Fulltext Prevalence of bronchial asthma among orang asli in peninsular Malaysia

Ngui R, Lim YA, Chow SC, de Bruyne JA, Liam CK

Med J Malaysia, 2011 Mar;66(1):27-31.

PMID: 23765139 MyJurnal

A survey was carried out to determine the prevalence of bronchial asthma and their contributing risk factors among Orang Asli subgroups living in Malaysia using IUATLD questionnaire and spirometry without being discriminatory towards age or gender. Of the 1171 distributed questionnaires, 716 (61.1%) comprising of 62.7% Semai Pahang, 51.3% Temiar, 74.2% Mah Meri, 65.6% Semai Perak, 53.6% Temuan, 53.8% Semelai, 61.1% Jakun and 67.4% Orang Kuala subgroups completed their questionnaire and were included in the data analysis. Participants comprised 549 (76.7%) children and 167 (23.3%) adults, age between 1 to 83 years old, 304 (42.5%) males and 412 (57.5%) females. The overall prevalence of bronchial asthma was 1.4% of which 1.5% was children, 1.3% adults, 1.0% male and 1.7% female, respectively. Of the 8 subgroups surveyed, 5 out of 10 confirmed asthma cases were Semai Pahang, followed by 3 cases among Mah Meri, and one case each among Temuan and Semai Perak subgroups, respectively. This study also demonstrated that the prevalence of self-reported and confirmed bronchial asthma tend to be higher among those who had close contact with pets, smoking individuals and among those who had a family history of asthma.

Matched MeSH terms: Prevalence

Pleuroscopy: early experience in an East malaysian state with high tuberculosis prevalence

Kannan SK, Lin WJ, Teck TS, Azizi AR

J Bronchology Interv Pulmonol, 2009 Oct;16(4):250-3.

PMID: 23168588 DOI: 10.1097/LBR.0b013e3181ba730a

Pleuroscopy using a flexi-rigid tube was introduced in Malaysia in late 2004 as part of the investigation for unexplained pleural effusion. Sabah, an East Malaysian state situated in Borneo, has the highest prevalence of tuberculosis (TB) in Malaysia. Therefore, exudative pleural effusion in Sabah was presumed to be predominantly because of TB.

Matched MeSH terms: Prevalence

Parent-reported pain in non-verbal children and adolescents with cerebral palsy

Jayanath S, Ong LC, Marret MJ, Fauzi AA

Dev Med Child Neurol, 2016 Apr;58(4):395-401.

PMID: 26510627 DOI: 10.1111/dmcn.12943

This cross-sectional study aimed to determine the prevalence, frequency, and intensity of parent-reported pain among non-verbal children with cerebral palsy (CP) and explore associations with medical, demographic, and parental psychosocial factors.

Matched MeSH terms: Prevalence

Fulltext Prevalence, awareness, treatment, control and socio demographic determinants of hypertension in Malaysian adults

Abdul-Razak S, Daher AM, Ramli AS, Ariffin F, Mazapuspavina MY, Ambigga KS, et al.

BMC Public Health, 2016;16(1):351.

PMID: 27097542 DOI: 10.1186/s12889-016-3008-y

Hypertension is the leading cardiovascular risk factor globally as well as in Malaysia. This study aimed to estimate the prevalence, awareness, treatment, control and the socio demographic determinants of hypertension among Malaysian adults.

Matched MeSH terms: Prevalence

Chronic kidney disease in Asia: Protocol for a collaborative overview

Liyanage T, Ninomiya T, Perkovic V, Woodward M, Stirnadel-Farrant H, Matsushita K, et al.

Nephrology (Carlton), 2017 Jun;22(6):456-462.

PMID: 27187157 DOI: 10.1111/nep.12821

AIM: The burden of chronic kidney disease (CKD) is growing rapidly around the world. However, there is limited information on the overall regional prevalence of CKD, as well as the prognostic implications and treatment patterns in Asian region. We have established the Asian Renal Collaboration (ARC) with the goal of consolidating region-wide data regarding CKD.

METHODS: This collaborative project will synthesize data and perform meta-analyses of observational studies conducted in Asia. Studies will be identified through a systematic literature search including abstracts, proceedings of meetings, electronic databases such as MEDLINE and EMBASE. Personal enquiry among collaborators and experts in the region will identify additional studies, or other data sources such as registries. Both cross-sectional and longitudinal studies that describe the prevalence of CKD and its complications will be included, as will longitudinal studies that describe important clinical outcomes for people with CKD. Individual participant data will be sought, where possible, from each of the studies included in the collaboration for baseline parameters and subsequent outcomes, in order to maximize flexibility and consistency of data analyses.

CONCLUSIONS: This study is an initiative offering a unique opportunity to obtain information about the prevalence and manifestations of CKD in Asia, as well as its risk factors. The ARC will also provide insights into important outcomes including progression of CKD, CKD complications, cardiovascular disease and death. These findings will improve our understanding of kidney disease in Asia, and thus help inform service provision, preventive care and further research across the region.

Matched MeSH terms: Prevalence

Fulltext Most prevalent unmet supportive care needs and quality of life of breast cancer patients in a tertiary hospital in Malaysia

Edib Z, Kumarasamy V, Binti Abdullah N, Rizal AM, Al-Dubai SA

Health Qual Life Outcomes, 2016;14:26.

PMID: 26898558 DOI: 10.1186/s12955-016-0428-4

Addressing breast cancer patients' unmet supportive care needs in the early stage of their survivorship have become a prime concern because of its significant association with poor quality of life (QOL), which in turn increases healthcare utilization and costs. There is no study about unmet supportive care needs of breast cancer patients in Malaysia. This study aims to assess the most prevalent unmet supportive care needs of Malaysian breast cancer patients and the association between QOL and patients' characteristics, and their unmet supportive care needs.

Matched MeSH terms: Prevalence

Prevalence of Intestinal Parasites among Food-handlers in Shiraz, Iran

Motazedian MH, Najjari M, Ebrahimipour M, Asgari Q, Mojtabavi S, Mansouri M

Iran J Parasitol, 2015 Oct-Dec;10(4):652-7.

PMID: 26811734

Parasitic intestinal infections are still among socioeconomic problems in the world, especially in developing countries like Iran. Food-handlers that directly deal with production and distribution of foods between societies are one of the most important sources to transmit parasitic infections to humans. The aim of this study was to determine the prevalence of intestinal parasitic infections among food-handlers in Shiraz, Iran.

Matched MeSH terms: Prevalence

Fulltext Impact of chronic obstructive pulmonary disease (COPD) in the Asia-Pacific region: the EPIC Asia population-based survey

Lim S, Lam DC, Muttalif AR, Yunus F, Wongtim S, Lan le TT, et al.

Asia Pac Fam Med, 2015;14(1):4.

PMID: 25937817 DOI: 10.1186/s12930-015-0020-9

Chronic obstructive pulmonary disease (COPD) is a clinical syndrome encompassing a group of chronic, progressive, and debilitating respiratory conditions, that are characterized by incompletely reversible airflow limitation. Within the Asia-Pacific region, prevalence estimates have been derived using various protocols and study methods, and there is little data on the impact of COPD exacerbations. This study aimed to provide a comprehensive picture of the current prevalence and burden of COPD in this region.

Matched MeSH terms: Prevalence

Medicine in Malaysia: ophthalmology

Selvarajah S

Med J Malaysia, 1995 May;50 Suppl A:S79-85.

PMID: 10968023

Matched MeSH terms: Prevalence

Fulltext Prevalence of giardiasis among Malaysian primary school children

Shekhar KC, Prathapa S, Gurpreet K

Med J Malaysia, 1996 Dec;51(4):475-9.

PMID: 10968037

Giardiasis, a gastrointestinal disease caused by Giardia intestinalis is endemic in Malaysia. The prevalence rate has been reported to range from 1.4% to 11.1%. The present study was undertaken between 1992-1994 in three health districts in three states viz. Pahang, Negeri Sembilan and Selangor. Seven thousand five hundred and fifty seven (7557) primary school children between the ages of 6-12 years from the lower socio-economic groups were screened. The prevalence was 0.21%. The study suggests that improved water supply, toilet facilities and sanitation have lowered the prevalence of a waterborne disease in the areas surveyed.

Matched MeSH terms: Prevalence

Fulltext Silicosis among tombstone makers in Malaysia

Jorgensen HS, Singh A

J Occup Med, 1978 Jun;20(6):385, 389, 391.

PMID: 671113

Matched MeSH terms: Prevalence

Fulltext Mapping of the beta-thalassaemia carrier in Sabah: an initial step to strengthen the Thalassaemia Prevention Program in Malaysia

Asit Sena, Saidatul Norbaya Buang, Mohd Shahriel Md Daud, Soh Chin Li, Zaleha Sulaiman, Kaharnisah Mat Noor, et al.

Malaysian Journal of Medicine and Health Sciences, 2019;15(104):13-13.

MyJurnal

Introduction: Thalassaemia is an autosomal recessive disorder affecting 5 percent of the Malaysian population. The state of Sabah has the highest number of transfusion dependent thalassaemia and β-thalassaemia carrier in Malay-sia. For Malaysia to be successful in the prevention of thalassaemia, Sabah needs to be focused on the preventive activities in areas with high prevalence of β-thalassaemia carriers. Thus, identifying the mapping of β-thalassaemia is crucial for planning for prevention activities. The objective of this study was to identify the prevalence of β-thalas-saemia by districts and ethnic groups in Sabah. Methods: This study used data from Form 4 Thalassaemia Screening Records in 2017. The data were cleaned and analysed using Excel spreadsheet to calculate for the national and state specific prevalence of β-thalassaemia carrier. Subsequently, the data was used for mapping of high-risk districts and ethnic groups in Sabah. Results: A total of 31,655 Form 4 students from 242 secondary schools were screened in Sa-bah in 2017 and 1150 (3.6%) were diagnosed as β-thalassemia carrier. The prevalence of β thalassaemia carrier was higher in the West Coast of Sabah which include Kota Marudi District (11.1%), Nabawan (9.0%), Tambunan (8%), Tongod (7.5%), Ranau (7.0%), Kota Belud (5.0%), Kudat (4.6%), Tenom (4.1%) and Tuaran (4.0%). In the East Coast of Sabah, there was only the Beluran District (5.0%) had prevalence that higher than the state average. β-thalassae-mia carriers were more likely to be of Dusun, Kadazan Dusun followed by Bajau, Murut and Rungus ethnic group. Conclusion: The distribution of β-thalassaemia carrier in Sabah was concentrated in the West Coast of Sabah and more common among the Dusun, Kadazan Dusun followed by Bajau, Murut and Rungus ethnic group. Thus, the thalassaemia prevention activities should be focuses in these areas and ethnic groups.

Matched MeSH terms: Prevalence

Prevalence of Chronic Kidney Disease in Asia: A Systematic Review of Population-Based Studies

Khan YH, Mallhi TH, Sarriff A, Khan AH, Tanveer N

J Coll Physicians Surg Pak, 2018 Dec;28(12):960-966.

PMID: 30501836 DOI: 10.29271/jcpsp.2018.12.960

Chronic kidney disease (CKD) is an asymptomatic disease associated with high morbidity and life-threatening complications that lead to decreased life expectancy. Worldwide prevalence of CKD is escalating at an alarming rate. Large population-based representative surveys have been reported in Western countries to estimate the prevalence of the disease. However, there is paucity of data as far as developing nations are concerned. Asia is the world's largest continent accommodating maximum number of under-developed and developing countries with an unclear picture of prevalence of CKD. Current review attempts to give an insight to the prevalence of CKD in this region by combining population-based surveys. This review will assist in estimating the burden of CKD in Asia, so that appropriate control measures could be designed.

Matched MeSH terms: Prevalence

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