Displaying publications 141 - 160 of 15493 in total

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  1. Suraya, A., Emy, S.R., Hamzaini, A.H., Sharifah, M.I.A., Maizatuljamny, M.
    MyJurnal
    Popliteal artery entrapment syndrome is an important infrequent cause of serious disability among young adults and athletes. We hereby describe a case of popliteal artery syndrome and its clinical implications. Physicians should be aware of the possibility of popliteal artery entrapment in young patients presenting with progressive arterial insufficiency.
    Matched MeSH terms: Adult; Young Adult
  2. Halim, A.S., Mohaini, M., L, Chin Keong
    JUMMEC, 2013;16(2):1-10.
    MyJurnal
    Human adipose tissue has been recognized as an alternative source of adult stem cells. The abundance and ease of harvest of adipose tissue has made it suitable for use in regenerative medicine and tissue engineering. Adipose-derived stem cells isolated from human adipose tissue are able to differentiate into several mesenchymal lineages and secrete growth factors that exhibit therapeutic potential. Protein profiles have been established using various isolation methods, which has expanded researchers’ understanding of adipose-derived stem cells in clinical applications. This review highlights the properties, isolation methods, immunophenotype and clinical applications of adipose-derived stem cells.
    Matched MeSH terms: Adult; Adult Stem Cells
  3. Wong, Jyh Eiin, Ahmad Munir Che Muhamed, Poh, Bee Koon
    MyJurnal
    Introduction: Accurate yet inexpensive methods for measuring free-living energy expenditure (EE) are
    much needed. The aim of this study was to determine the feasibility of heart-rate monitoring method
    (HRM) in measuring EE as compared to the established activity diary (AD) method. Methodology:
    Minute-by-minute HRM and an activity diary (AD) were used simultaneously in 34 young adults (18
    females, 16 males; mean age 21.5 ± 1.5 years). Estimates of the EE from HRM were based on individual
    calibration using the Flex-HR procedure while EE from AD were calculated using both individually
    measured and published energy cost of various activities. Total daily energy expenditure (TDEE) and its
    components (EE during sleep, during rest and during physical activity) were compared using Student
    paired-t tests. Results: TDEE from HRM method averaged 8.17 ± 2.00 MJ/day compared to 8.50 ±
    1.28 MJ/day from AD method. Although large intra-individual differences were found (ranging from
    -36.9% to 47.4%), there was no significant difference between the two methods (mean difference -3.6 ± 19.4%). The limits of agreement (mean ± 2SD) were -3.77 and 3.11 MJ/day. There were no significant
    differences for any of the TDEE components between the two methods, except for EE during sleep
    (p
    Matched MeSH terms: Adult; Young Adult
  4. Vosoughi AR, Erfani MA
    Malays Orthop J, 2018 Mar;12(1):57-59.
    PMID: 29725517 DOI: 10.5704/MOJ.1803.014
    Peroneal tendon dislocation in association with medial malleolus fracture is a very rare traumatic injury to the ankle. A 19-year old male patient was referred after injury sustained in a motorcycle accident with car, with concomitant traumatic peroneal tendon dislocation and medial malleolus fracture. The possible mechanism of this unusual injury could have been sudden external rotation force to the pronated foot in full dorsiflexed position of the ankle. Diagnosis of peroneal tendon subluxation or dislocation should be carefully evaluated in patients with single medial malleolus fracture.
    Matched MeSH terms: Adult; Young Adult
  5. Siti Radziah Shaik Alaudeen, Aszrin Abdullah, Azarisman Shah Mohd Shah, Norlelawati Abdul Talib
    MyJurnal
    Copy number variation (CNV) caused by changes in DNA sequences of 1000
    or more bases is implicated with susceptibility to common diseases. A study on CNV
    esv27061 among hypertensive Australian adults reported association with high blood
    pressure (BP). In Malaysia, no study on CNV among hypertensive young adults is
    available. Thus, this investigation aimed to assess the CNV esv27061 of young Malaysian
    adults with high blood pressure using optimized ddPCR. (Copied from article).
    Matched MeSH terms: Adult; Young Adult
  6. Ang KC, Kathirgamanathan S, Ch'ng ES, Abdullah WZ, Yusoff NM, Jahnke CM, et al.
    Thromb Res, 2017 08;156:87-90.
    PMID: 28605660 DOI: 10.1016/j.thromres.2017.06.008
    Matched MeSH terms: Adult; Young Adult
  7. Ferreira CWS, Atan IK, Martin A, Shek KL, Dietz HP
    Int Urogynecol J, 2017 Oct;28(10):1499-1505.
    PMID: 28285396 DOI: 10.1007/s00192-017-3297-4
    INTRODUCTION AND HYPOTHESIS: Female pelvic organ prolapse is highly prevalent and childbirth has been shown to be an important risk factor. The study was carried out to observe if pelvic organ support deteriorates over time following a first birth.

    METHODS: This is a retrospective review using archived data sets of women seen in the context of two prospective perinatal imaging studies. All subjects had undergone a standardised interview, a clinical examination and 4D translabial ultrasound, 3 months and 2-5 years post-partum. Main outcome measures were pelvic organ descent and hiatal area at maximum Valsalva manoeuvre. Means at the two time points were compared using paired Student's t test. Predictors of change over time in continuous variables were explored using linear modelling methods.

    RESULTS: A total of 300 women had at least two postnatal follow-ups. They were first seen on average 0.39 (SD 0.2, range 0.2-2.1) years and again 3.1 (SD 1.5, range 1.4-8) years after the index delivery, with a mean interval of 2.71 (SD 1.5, range 0.7-7.7) years, providing a total of 813 (300 × 2.71) woman-years of observation. On univariate analysis, there was a significant decrease in mobility over time of the bladder neck, bladder, and rectal ampulla (P = < 0.004) and hiatal area (P = 0.012). The degree of improvement was less marked in women with levator avulsion.

    CONCLUSIONS: A significant reduction in pelvic organ descent and hiatal area was noted over a mean of 2.7 years after a first birth.

    Matched MeSH terms: Adult; Young Adult
  8. Hung LC, Nadia R
    Med J Malaysia, 2016 06;71(Suppl 1):79-86.
    PMID: 27801390 MyJurnal
    A total of 39 titles related to rheumatic fever or rheumatic heart disease in Malaysia were found with online literature search dating back to their inceptions and through 2014. Additional publications from conference journals were included. Nine papers were selected based on clinical relevance and future research implications. There were no population-based studies on the incidence or prevalence of ARF or RHD. In the 1980s, the incidence of admission due to ARF ranged from 2 to 21.1 per 100 000 paediatric admission per year. The burden of disease was significant in the adult population; 74.5% of patients with RHD were female, of which 77.1% were in the reproductive age group of 15-45 years old. Rheumatic mitral valve disease constituted almost half (46.7%) of all mitral valve repairs, ranging from 44.8 - 55.8 patients per year from 1997 - 2003. From 2010-2012, mitral valve interventions increased to 184 per year, of which 85.7% were mitral valve repair. In children with ARF, 25.4% - 41.7% had past history of rheumatic fever or RHD. In patients with rheumatic mitral valve disease undergoing surgical or medical interventions, only 6% reported history of ARF, none had history of GABHS pharyngitis or antibiotic prophylaxis. Only 44.7% of patients with RHD on follow-up were on intramuscular benzathine penicillin prophylaxis. Overall, there is scarcity of publications on ARF and RHD in Malaysia. Priority areas for research include determination of the incidence and prevalence of ARF and RHD, identification of high-risk populations, evaluation on the implementation and adherence of secondary preventive measures, identification of subclinical RHD especially amongst the high-risk population, and a surveillance system to monitor and evaluate preventive measures, disease progression and outcomes.
    Matched MeSH terms: Adult; Young Adult
  9. Ekker MS, Boot EM, Singhal AB, Tan KS, Debette S, Tuladhar AM, et al.
    Lancet Neurol, 2018 09;17(9):790-801.
    PMID: 30129475 DOI: 10.1016/S1474-4422(18)30233-3
    Epidemiological evidence suggests that the incidence of ischaemic stroke in young adults (18-50 years) has increased substantially. These patients have a long life expectancy after stroke, and the costs of long-term care pose huge challenges to health-care systems. Although the current recommendations for treatment of young and old (>50 years) patients with stroke are similar, the optimal management of young adult patients with stroke is unknown. They are usually not included in trials, and specific subanalyses limited to young adult patients with stroke are usually not done, owing to lower incidence of stroke and lower prevalence of vascular risk factors in young adults. Progress has been made in identifying patients with a considerable risk of stroke occurrence, such as those with patent foramen ovale. Future prevention studies might result in a decrease in the incidence of stroke and its sequelae in young adults. The development of guidelines specifically devoted to the management of stroke in young adults will be an important step in achieving this aim.
    Matched MeSH terms: Adult; Young Adult
  10. Chan CY, Mohamed N, Ima-Nirwana S, Chin KY
    PMID: 30103534 DOI: 10.3390/ijerph15081727
    Osteoporosis is a major public health problem affecting millions of people worldwide. Increasing knowledge, correcting health belief and promoting osteoprotective practices are effective measures for building and maintaining strong bone throughout ones' life-span. This review aims to summarize the contemporary evidence on the knowledge, beliefs and practice of adolescents and young adults on bone health. We performed literature searches using the PubMed and Scopus databases to identify original studies from 2008 to May 2018 using the search terms "(knowledge OR beliefs OR attitude OR practice OR behaviours OR physical activity OR exercise OR diet OR nutrition) AND (young OR youth OR adolescents OR children OR young adults OR students OR teenager) AND (osteoporosis OR bone health)". Of the 3206 articles found, 34 met the inclusion criteria. Studies showed that most adolescents and young adults had poor knowledge and expressed disinterest in osteoporosis. They believed that other diseases were more serious than osteoporosis, contributing to low perceived susceptibility and seriousness towards this disease. Popular media emerged as a platform to obtain information regarding osteoporosis. The lack of knowledge and misconceptions about osteoporosis led to poor osteoprotective practices. As a conclusion, the current evidence revealed a lack of awareness about osteoporosis among adolescents and young adults. Educational interventions may be useful to improve the awareness of osteoporosis among this population.
    Matched MeSH terms: Adult; Young Adult
  11. Nema SK, Behera G, Poduval M
    Malays Orthop J, 2018 Jul;12(2):65-67.
    PMID: 30112134 DOI: 10.5704/MOJ.1807.016
    We present an unusual case of five months old neglected anterior dislocation of the right elbow joint in a 19-year old man. The patient had been initially treated by a traditional bone setter, but the elbow remained unreduced. He presented to us with pain, deformity and limited range of motion of his right elbow joint. Radiographs revealed an unreduced anterior dislocation of the right elbow joint. We describe the problems encountered during open reduction and rehabilitation and result one year after the operation with the patient having a stable elbow and a functional range of motion.
    Matched MeSH terms: Adult; Young Adult
  12. Hasan MN, Banarjee SK, Ahsan SA, Habib SM, Mahmood M
    Mymensingh Med J, 2018 Oct;27(4):851-858.
    PMID: 30487504
    Mitral stenosis (MS) affects left atrial (LA) function as a result of hemodynamic and myocardial factors that causes significant symptoms and complications. Conventional echocardiographic methods have been practicing to see the improvement of left atrial function after successful percutaneous mitral balloon valvuloplasty (PMBV). Introduction of tissue doppler imaging allows direct and non-invasive measurement of myocardial velocities. The aim of the study was to evaluate LA functions after PMBV using colour tissue doppler imaging. This cross sectional study was performed in Cardiology department of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from March 2014 to February 2015. Forty six (46) patients (28 females, mean age: 28.96±5.78 years) presenting with mitral valve stenosis who fulfilled the indications for PMBV were included in the study. Within 24 hours before PMBV, all the patients underwent colour tissue doppler study in addition to routine conventional echocardiographic examinations. Late diastolic velocities (A') measured at the septal and lateral annuli were recorded. All the measurements were repeated 24 hours after PMBV. The PMBV was done using the Inoue technique. After PMBV mitral valve areas (MVA) were significantly increased. Maximum and mean gradients, LA diameter, LA area, LA volume, systolic pulmonary arterial pressure and mean LA pressures were decreased while septal and lateral A' were significantly (p<0.001) increased. Lateral and septal A' velocities were correlated with MVA and inversely related to LA pressure measured invasively during PMBV. Tissue doppler velocities illustrated improvement of left atrial systolic function after PMBV in relation to decreased mean left atrial pressure and increased mitral valve area. Therefore, tissue doppler Imaging is a useful tool to detect improvement of left atrial systolic function after PMBV in patients with mitral stenosis.
    Matched MeSH terms: Adult; Young Adult
  13. Alammar A, Heshmeh O, Mounajjed R, Goodson M, Hamadah O
    J Esthet Restor Dent, 2018 11;30(6):523-531.
    PMID: 30412347 DOI: 10.1111/jerd.12433
    AIM: The aim of this study was to evaluate and compare conventional and modified lip repositioning surgical techniques used for management of gummy smile involving hyperactive lip elevator muscles.

    METHODS AND MATERIALS: A prospective study was conducted between April 2016 and May 2017. Twenty two adult patients aged 18-38 years with gummy smile ranging from 4 to 6 mm because of soft tissue disorders were included in the study. All patients were treated in the oral and maxillofacial department at Damascus University. The sample was divided into two groups of 11 patients. The first group was treated by the conventional standard technique, and the second group treated by a modified study technique. The amount of gingival display in full smile was evaluated in both groups following each intervention.

    RESULTS: Both groups exhibited a statistically significant reduction in the measurement of gummy smile at month 1 and 6 postoperatively (P  .05). The recent study showed a significant difference in gingival display between 3 and 6 months postoperatively in group 1, but no significant difference in group 2.

    CONCLUSION: This study showed that the modified technique utilized in treating gummy smile has less relapse after surgery, shows excellent cosmesis and compared to the conventional technique, greater sustainability.

    CLINICAL SIGNIFICANCE: The recent increase in demand for an esthetic smile has led to the development a modification of conventional lip repositioning for correcting gummy smile by myotomy of lip elevator muscles. This modified technique offers less relapse and greater stability post-operatively than the conventional technique.

    Matched MeSH terms: Adult; Young Adult
  14. Linnell RM
    Lancet, 1914;183:1608-9.
    DOI: 10.1016/S0140-6736(01)58348-8
    Matched MeSH terms: Adult; Young Adult
  15. Mat Yudin Z, Ali K, Wan Ahmad WMA, Ahmad A, Khamis MF, Brian Graville Monteiro N', et al.
    Eur J Dent Educ, 2020 Feb;24(1):163-168.
    PMID: 31698535 DOI: 10.1111/eje.12480
    AIMS: To evaluate the self-perceived preparedness of final-year dental undergraduate students in dental public universities in Malaysia.

    METHODS: Final-year dental undergraduate students from six dental public universities in Malaysia were invited to participate in an online study using a validated Dental Undergraduates Preparedness Assessment Scale DU-PAS.

    RESULTS: In total, about 245 students responded to the online questionnaire yielding a response rate of 83.05%. The age range of the respondents was 23-29 years with a mean age of 24.36 (SD 0.797). The total score obtained by the respondents was ranged from 48 to 100 with a mean score of 79.56 (SD 13.495). Weaknesses were reported in several clinical skills, cognitive and behavioural attributes.

    CONCLUSIONS: The preparedness of undergraduate students at six dental institutions in Malaysia was comparable to students from developed countries. The dental undergraduate preparedness assessment scale is a useful tool, and dental institutions may be used for self-assessment as well as to obtain feedback from the supervisors.

    Matched MeSH terms: Adult; Young Adult
  16. Smith GH
    Lancet, 1841;37:291-292.
    DOI: 10.1016/S0140-6736(02)81752-4
    Matched MeSH terms: Adult; Young Adult
  17. Sherina MS, Rampal L, Kaneson N
    Objective: This study was conducted to determine the prevalence of anxiety among medical students at a local university in Malaysia and to identify its associated factors.
    Methods: Across-sectional study design was used. Three-hundred and ninety-six medical students at a local university in Malaysia were included in the study. A pre-tested, modified, self-administered Beck Anxiety Inventory (BAI) was used to screen for anxiety.
    Results: Three-hundred-and-ninety-six out of 414 medical students participated (response rate 95.7%).38.4% of the medical students were found to have anxiety.
    Conclusion: The overall prevalence of anxiety among medical students was high (38.4%). Factors found to be significantly associated with anxiety were gender, perceived level of pressure, year of study in medical school, ethnicity and depression(p<0.05).
    Keywords: Anxiety, depression, medical students, prevalence
    Matched MeSH terms: Adult; Young Adult
  18. Berry C, Michelson D, Othman E, Tan JC, Gee B, Hodgekins J, et al.
    Early intervention in psychiatry, 2020 02;14(1):115-123.
    PMID: 31111672 DOI: 10.1111/eip.12832
    AIM: Mental health problems are prevalent among young people in Malaysia yet access to specialist mental health care is extremely limited. More context-specific research is needed to understand the factors affecting help-seeking in youth, when mental health problems typically have first onset. We aimed to explore the attitudes of vulnerable young Malaysians regarding mental health problems including unusual psychological experiences, help-seeking and mental health treatment.

    METHODS: In the present study, nine young people (aged 16-23 years) from low-income backgrounds participated in a semi-structured interview about their perspectives on mental health problems, unusual psychological experiences and help-seeking.

    RESULTS: Four themes were developed using thematic analysis. "Is it that they [have] family problems?" reflected participants' explanatory models of mental health problems. "Maybe in Malaysia" was concerned with perceptions of Malaysian culture as both encouraging of open sharing of problems and experiences, but also potentially stigmatizing. "You have to ask for help" emphasized the importance of mental health help-seeking despite potential stigma. "It depends on the person" addressed the challenges of engaging with psychological therapy.

    CONCLUSIONS: We conclude that young people in Malaysia may hold compassionate, non-stigmatizing views towards people experiencing mental health problems and a desire to increase their knowledge and understandings. Yet societal stigma is a perceived reputational risk that may affect mental health problem disclosure and help-seeking. We suggest that efforts to improve mental health literacy would be valued by young Malaysians and could support reduced stigma and earlier help-seeking.

    Matched MeSH terms: Adult; Young Adult
  19. Matthew TJH, Hussein A
    Cureus, 2018 Dec 04;10(12):e3685.
    PMID: 30761237 DOI: 10.7759/cureus.3685
    Cavernous sinus thrombosis (CST) is an ocular emergency because of its devastating effect and it is prone to cause serious complications. Diagnosis of cavernous sinus thrombosis is a challenging task despite medical advancement. Efforts to promptly diagnose and initiate treatment require a high index of suspicion and a deep understanding of the disease. Unfortunately, patients suffering from CST may not always present with typical symptoms, thus making diagnosis all the more challenging. We would like to describe a 22-year-old man who presented with atypical symptoms and radiological presentations of CST. The patient was admitted and treated in our institution with full recovery demonstrated after the treatment.
    Matched MeSH terms: Adult; Young Adult
  20. Ahmad-Shushami AH, Abdul-Karim S
    Malays Orthop J, 2020 Mar;14(1):28-33.
    PMID: 32296479 DOI: 10.5704/MOJ.2003.005
    Introduction: Football and futsal were the main sports in the Malaysian Games. However, they were associated with a risk of injury. The purpose of the study was to analyse the incidence, circumstances, and characteristics of football and futsal injuries during the Malaysian Games of 2018.

    Materials and method: During the tournament, 14 teams participated in men's football, 12 teams in men's futsal and 11 teams in women's futsal. The biannual event involved athletes aged under 21 years. A medical report form used by FIFA Medical Assessment and Research Centre (F-Marc), was provided to the physiotherapists and team doctors of all the teams to report all injuries after each match.

    Results: The response rate was 84.62% in football and 59.76% in futsal. A total of 48 injuries were reported from 26 football matches, equivalent to 64.64 injuries per 1000 match hours (95%CI 46.35 to 82.93). In futsal, a total of 48 injuries from 41 matches were reported, equivalent to 292.42 injuries per 1000 match hours (95% CI 209.7 to 375.14). The rate of injury in women futsal players was higher compared to men: 358.21 versus 247.04 injuries per 1000 match hours (p=0.224). Futsal recorded higher injuries per 1000 match hours than football (p<0.001).

    Conclusion: The rate of severe injury in futsal and football recorded in the study as compared to previous studies gave rise to serious concerns. Hence, there was an urgent need to pay more attention to injury prevention strategies.

    Matched MeSH terms: Adult; Young Adult
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