Displaying publications 161 - 180 of 349 in total

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  1. Islam KMM, Asadullah MN
    PLoS One, 2018;13(1):e0190807.
    PMID: 29351305 DOI: 10.1371/journal.pone.0190807
    Using government secondary school English language textbooks from Malaysia, Indonesia, Pakistan and Bangladesh, we conducted a quantitative content analysis in order to identify gender stereotypes in school education. In total, 21 categories of exclusion and quality of representation were used to study gender stereotypes. Our analysis confirms a pro-male bias in textbooks: the aggregate female share is 40.4% in textual and pictorial indicators combined. Female occupations are mostly traditional and less prestigious while the characters are predominantly introverted and passive in terms of personality traits. Women are also shown to be mostly involved in domestic and in-door activities while men have a higher presence in professional roles. Systematic underrepresentation of females is evident regardless of whether we look at the text or pictures. A cross-country analysis shows that the female share in picture content is only 35.2% in Malaysia and Bangladesh. Overall, the proportion of female to male characters (text and pictures combined) is balanced in Malaysia and Indonesia (44.4% and 44.1% respectively) while this share is only 24.4% and 37.3% in Pakistani and Bangladeshi textbooks respectively. The finding of underrepresentation of women in Pakistani textbooks, in terms of quality and quantity, is robust to the selection of province-, grade- and subject-specific textbooks, as well as the range and type of categories used.
    Matched MeSH terms: Bangladesh
  2. Alam S, Dhar A, Hasan M, Richi FT, Emon NU, Aziz MA, et al.
    Molecules, 2022 Dec 08;27(24).
    PMID: 36557843 DOI: 10.3390/molecules27248709
    Diabetes mellitus is a life-threatening disorder affecting people of all ages and adversely disrupts their daily functions. Despite the availability of numerous synthetic-antidiabetic medications and insulin, the demand for the development of novel antidiabetic medications is increasing due to the adverse effects and growth of resistance to commercial drugs in the long-term usage. Hence, antidiabetic phytochemicals isolated from fruit plants can be a very nifty option to develop life-saving novel antidiabetic therapeutics, employing several pathways and MoAs (mechanism of actions). This review focuses on the antidiabetic potential of commonly available Bangladeshi fruits and other plant parts, such as seeds, fruit peals, leaves, and roots, along with isolated phytochemicals from these phytosources based on lab findings and mechanism of actions. Several fruits, such as orange, lemon, amla, tamarind, and others, can produce remarkable antidiabetic actions and can be dietary alternatives to antidiabetic therapies. Besides, isolated phytochemicals from these plants, such as swertisin, quercetin, rutin, naringenin, and other prospective phytochemicals, also demonstrated their candidacy for further exploration to be established as antidiabetic leads. Thus, it can be considered that fruits are one of the most valuable gifts of plants packed with a wide spectrum of bioactive phytochemicals and are widely consumed as dietary items and medicinal therapies in different civilizations and cultures. This review will provide a better understanding of diabetes management by consuming fruits and other plant parts as well as deliver innovative hints for the researchers to develop novel drugs from these plant parts and/or their phytochemicals.
    Matched MeSH terms: Bangladesh
  3. Siraz MMM, Roy D, Dewan MJ, Alam MS, A M J, Rashid MB, et al.
    Environ Monit Assess, 2023 Feb 10;195(3):382.
    PMID: 36759352 DOI: 10.1007/s10661-023-10921-7
    This is the first attempt in the world to depict the vertical distribution of radionuclides in the soil samples along several heights (900 feet, 1550 feet, and 1650 feet) of Marayon Tong hill in the Chittagong Hill Tracts, Bandarban by HPGe gamma-ray spectrometry. The average activity concentrations of 232Th, 226Ra, and 40K were found to be 37.15 ± 3.76 Bqkg-1, 19.69 ± 2.15 Bqkg-1, and 347.82 ± 24.50 Bqkg-1, respectively, where in most cases, 232Th exceeded the world average value of 30 Bqkg-1. According to soil characterization, soils ranged from slightly acidic to moderately acidic, with low soluble salts. The radium equivalent activity, outdoor and indoor absorbed dose rate, external and internal hazard indices, external and internal effective dose rates, gamma level index, and excess lifetime cancer risk were evaluated and found to be below the recommended or world average values; but a measurable activity of 137Cs was found at soils collected from ground level and at an altitude of 1550 feet, which possibly arises from the nuclear fallout. The evaluation of cumulative radiation doses to the inhabitants via periodic measurement is recommended due to the elevated levels of 232Th.This pioneering work in mapping the vertical distribution of naturally occurring radioactive materials (NORMs) can be an essential factual baseline data for the scientific community that may be used to evaluate the variation in NORMs in the future, especially after the commissioning of the Rooppur Nuclear Power Plant in Bangladesh in 2024.
    Matched MeSH terms: Bangladesh
  4. Shah IH
    Environ Sci Pollut Res Int, 2021 Jan;28(3):2707-2718.
    PMID: 32892281 DOI: 10.1007/s11356-020-10662-x
    The efficient consumption of material and energy resources, with minimal carbon emissions and maximum economic output, is globally significant. This study examines the metabolic transition of resource use and CO2 emissions in nine of the largest economies of East, South, and Southeast Asia. A data envelopment model has been developed to assess the efficiency of domestic material consumption and CO2 emissions during 1971-2016 at three levels of analysis. The single-country analysis results reveal that China has made the most rapid efficiency transformation during 1971-2016 followed by Japan and South Korea, while the rest of the countries in South and Southeast Asia have not illustrated significant improvements. Results from the analysis of socio-economically grouped countries show that Japan and Bangladesh are the relatively efficient economies in East and South Asia, respectively. Among Southeast Asian countries, both Indonesia and Malaysia were found to be efficient. Based on the regional analysis comparing all nine countries, Japan has consistently remained a relatively efficient economy while China-despite rapid improvements-remains a relatively inefficient economy. To this end, Japan had the lowest material and CO2 intensities compared to all other countries. Based on our results, technological advancement, industry structure, and scale of traded goods and services were found to have a significant impact (the impact of per capita income was less pronounced) on a country's effective resource utilization and carbon mitigation.
    Matched MeSH terms: Bangladesh
  5. Abbasi MA, Parveen S, Khan S, Kamal MA
    Environ Sci Pollut Res Int, 2020 May;27(15):18029-18043.
    PMID: 32170610 DOI: 10.1007/s11356-020-08262-w
    The developing world is facing pivotal challenges in recent times. Among these, global warming has ominous repercussions on every segment of society, thus tracing its underlying causes is imperative. This research attempts to investigate the impact of urbanization and energy consumption on carbon dioxide emissions (CO2) for a panel of 8 Asian countries (Bangladesh, China, India, Indonesia, Malaysia, Nepal, Pakistan, and Sri Lanka) over the period 1982 to 2017. The analyses are executed using panel co-integration and Granger causality techniques. The main findings of panel co-integration reveal a long-run relationship between urbanization, energy consumption, and CO2 emissions. Furthermore, the results indicate a positive and significant impact of urbanization and energy consumption on CO2 emissions, indicating that urban development and high energy consumptions are barriers to improve environmental quality in the long run. The results also highlight bi-directional causality between energy consumption and urbanization, while unidirectional causality exists between energy consumption and CO2 emissions. Based on the obtained results, this study offers useful policy implications for plummeting carbon emissions.
    Matched MeSH terms: Bangladesh
  6. Siraz MMM, Kamal MH, Khan ZH, Alam MS, Al Mahmud J, Rashid MB, et al.
    Environ Monit Assess, 2023 Aug 10;195(9):1028.
    PMID: 37558890 DOI: 10.1007/s10661-023-11636-5
    This study marks the first-ever assessment of radiological hazards linked to the sands and rocks of Patuartek Sea Beach, situated along one of the world's longest sea beaches in Cox' Bazar of Bangladesh. Through the utilization of an HPGe detector, a comprehensive analysis of the activity concentrations of 226Ra, 232Th, and 40 K was conducted, and their activity ranged from 7 to 23 Bq/kg, 9-58 Bq/kg, and 172-340 Bq/kg, respectively, in soils, and 19-24 Bq/kg, 27-39 Bq/kg, and 340-410 Bq/kg, respectively, in rocks. Some sand samples exhibited elevated levels of 232Th, while the rock samples displayed higher levels of 40 K compared to the global average. The radiological hazard parameters were assessed, and no values surpassed the recommended limits set by several international organizations. Hence, the sands and rocks of Patuartek sea beach pose no significant radiological risk to the residents or tourists. The findings of this study provide crucial insights for the development of a radiological baseline map in the country, which is important due to the commissioning of the country's first nuclear power plant Rooppur Nuclear Power Plant. The data may also stimulate interest in the rare-earth minerals present in the area, which is important for the electronics industry, thorium-based nuclear fuel cycles.
    Matched MeSH terms: Bangladesh
  7. Jobaer MA, Ashrafi S, Ahsan M, Hasan CM, Rashid MA, Islam SN, et al.
    Molecules, 2023 May 19;28(10).
    PMID: 37241926 DOI: 10.3390/molecules28104186
    Gynura procumbens (Lour.) Merr. (Family: Asteraceae) is a tropical Asian medicinal plant found in Thailand, China, Malaysia, Indonesia, and Vietnam. It has long been utilized to treat a variety of health concerns in numerous countries around the world, such as renal discomfort, constipation, diabetes mellitus, rheumatism, and hypertension. The chemical investigation resulted in the isolation and characterization of six compounds from the methanol (MeOH) extract of the leaves of Gynura procumbens, which were identified as phytol (1), lupeol (2), stigmasterol (3), friedelanol acetate (4), β-amyrin (5), and a mixture of stigmasterol and β-sitosterol (6). In-depth investigations of the high-resolution 1H NMR and 13C NMR spectroscopic data from the isolated compounds, along with comparisons to previously published data, were used to clarify their structures. Among these, the occurrence of Compounds 1 and 4 in this plant are reported for the first time. The crude methanolic extract (CME) and its different partitionates, i.e., petroleum ether (PESF), chloroform (CSF), ethyl acetate (EASF), and aqueous (AQSF) soluble fractions, were subjected to antioxidant, cytotoxic, thrombolytic, and anti-diabetic activities. In a DPPH free radical scavenging assay, EASF showed the maximum activity, with an IC50 value of 10.78 µg/mL. On the other hand, CSF displayed the highest cytotoxic effect with an LC50 value of 1.94 µg/mL compared to 0.464 µg/mL for vincristine sulphate. In a thrombolytic assay, the crude methanolic extract exhibited the highest activity (63.77%) compared to standard streptokinase (70.78%). During the assay for anti-diabetic activity, the PESF showed 70.37% of glucose-lowering activity, where standard glibenclamide showed 63.24% of glucose-reducing activity.
    Matched MeSH terms: Bangladesh
  8. Huq AK, Jamal JA, Stanslas J
    PMID: 24834098 DOI: 10.1155/2014/782830
    Persicaria hydropiper (L.) Delarbre, belonging to Polygonaceae family, is a common weed found in most of the temperate countries including Bangladesh, China, Malaysia, and Japan. The plant is also referred to as "marsh pepper" or "smart weed." It appears to be a useful herb with evidence-based medicinal properties. The present work addresses the botanical description, traditional uses, phytochemistry, pharmacology, and toxicology of P. hydropiper. All plant parts have been commonly used in the traditional systems of medicines. Flavonoids are the major group of phytochemical components followed by drimane-type sesquiterpenes and sesquiterpenoids, as well as phenylpropanoids. Different extracts and plant parts showed remarkable pharmacological activities including antioxidant, antibacterial, antifungal, antihelminth, antifeedant, cytotoxicity, anti-inflammatory, antinociceptive, oestrogenicity, antifertility, antiadipogenicity, and neuroprotection. Mutagenicity and acute and subchronic toxicities of the plant were also reported. P. hydropiper has tremendous medicinal properties that could further be investigated for the development of evidence-based herbal products.
    Matched MeSH terms: Bangladesh
  9. Islam MS, Al Bakky A, Ahmed S, Islam MT, Antu UB, Saikat MSM, et al.
    Food Chem Toxicol, 2024 Nov;193:115005.
    PMID: 39284411 DOI: 10.1016/j.fct.2024.115005
    As a cereal crop, maize ranked third place after wheat and rice in terms of land area coverage for its cultivation, and in Bangladesh, it ranked second place after rice in its production. As the substitution of wheat products, maize has been used widely in baking for human consumption and animal fodder. However, maize grown in this soil around the coal-burning power plant may cause heavy metals uptake that poses a risk to humans. The study was conducted at the maize fields in the Ganges delta floodplain soils of Bangladesh to know the concentration of eight heavy metals (Ni, Cr, Cd, Mn, As, Cu, Zn, and Pb) in soil and maize samples using an inductively coupled plasma mass spectrometer (ICP-MS) and to estimate the risk of heavy metals in maize grains. Mean concentrations of heavy metals (mg/kg) in soil were in decreasing order of Zn (10.12) > Cu (10.02) > Mn (5.48) > Ni (4.95) > Cr (3.72) > As (0.51) > Pb (0.27) > Cd (0.23). The plant tissues showed the descending order of heavy metal concentration as roots > grains > stems > leaves. BCF values for As, Cd, Pb, and Mn in roots were higher than 1.0, indicating considerable accumulation of these elements in maize via roots. Total hazard quotient (ƩTHQ) of heavy metals through maize grain consumption was 3.7E+00 and 3.9E+00 for adults and children, respectively, indicating non-cancer risk to the consumers. Anthropogenic influences contributed to the heavy metals enrichment in the Ganges delta floodplain soils around the thermal plant, and potential risks (non-carcinogenic and carcinogenic) were observed due to the consumption of maize grain cultivated in the study area.
    Matched MeSH terms: Bangladesh
  10. Kafy AA, Dey NN, Saha M, Altuwaijri HA, Fattah MA, Rahaman ZA, et al.
    J Environ Manage, 2024 Nov;370:122427.
    PMID: 39305877 DOI: 10.1016/j.jenvman.2024.122427
    Climate change and rapid urbanization are dramatically altering coastal ecosystems worldwide, with significant implications for land surface temperatures (LST) and carbon stock concentration (CSC). This study investigates the impacts of day and night time LST dynamics on CSC in Cox's Bazar, Bangladesh, from 1996 to 2021, with future projections to 2041. Using Landsat and MODIS imagery, we found that mean daytime LST increased by 3.57 °C over the 25-year period, while nighttime LST showed a slight decrease of 0.05 °C. Concurrently, areas with no carbon storage increased by 355.78%, while high and very high CSC zones declined by 14.15% and 47.78%, respectively. The Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST) model estimated a 28.64 km2 reduction in high CSC areas from 1996 to 2021. Statistical analysis revealed strong negative correlations between LST and vegetation indices (R2 = -0.795 to -0.842, p 32 °C, while areas with LST <24 °C may decrease to 1.68%. These observations underscore the pressing necessity for sustainable strategies in urban planning and conservation in swiftly evolving coastal areas, especially considering the challenges posed by climate change and population growth.
    Matched MeSH terms: Bangladesh
  11. Adam RI, Rajaratnam S, Sufian FD, Njogu L
    PLoS One, 2025;20(1):e0314284.
    PMID: 39792835 DOI: 10.1371/journal.pone.0314284
    Gender equality and women's empowerment have been increasingly emphasised in food production systems, including fisheries and aquaculture. Accurate assessment and understanding of the state, progress and changes in women's empowerment in the sub-sectors is required. We applied the project level Women's Empowerment in Fisheries and Aquaculture Index (pro-WEFI), which is based on the project-level women's empowerment in agriculture index (pro-WEAI) to standardize the measurement of women's agency and empowerment in fisheries and aquaculture. Drawing on a survey conducted in north-western Bangladesh, we examined quantitative pro-WEFI data collected from 217 households engaged in aquaculture. Only 33% of the women and 48% of the men in the sample achieved empowerment in aquaculture, attaining scores of 0.75 and above. The mean disempowerment score (1-3DE) revealed that both women and men failed to achieve adequacy on average in nearly 28% of the indicators. Nearly 40% of the dual adult households did not attain gender parity with women achieving lower adequacy scores than men from the same household. Women's disempowerment was primarily driven by lack of autonomy in their use of income (18.5%), inability to visit important locations (17.4%), and inadequate access to and decision making on financial services (13.4%). Our findings emphasize the significance of conducting comprehensive assessments of women's empowerment in aquaculture initiatives and its various domains and indicators inform the development of targeted and effective interventions. By identifying domains where gender inequality is most pronounced, projects can better design interventions to create targeted impacts in critical areas.
    Matched MeSH terms: Bangladesh
  12. Jain D
    Int J Gynaecol Obstet, 2025 Mar;168(3):1345-1351.
    PMID: 39711117 DOI: 10.1002/ijgo.16119
    In Asia as elsewhere, strict regulations on who is authorized to provide abortion services and to prescribe or dispense medical abortion adversely impact access, especially for marginalized persons and residents in remote areas. The WHO's 2022 Abortion Care Guideline provides an important framework for states to formulate and implement policies to serve sexual and reproductive rights of access to abortion services. The Guideline calls for decriminalization of abortion services to increase authorization to provide abortion services and to promote self-managed medical abortion. This review examines the legal and policy frameworks of Bangladesh, India, Indonesia, Malaysia, and Nepal against the WHO Guideline. Legal and policy reforms successfully introduced in Bangladesh and Nepal to grow the provider base allow healthcare systems to expand safe abortion. This review outlines further challenges where the WHO Guideline on decriminalization and availability of medical abortion is disregarded and advocates a reproductive justice approach promoting egalitarian access to services even among the most marginalized.
    Matched MeSH terms: Bangladesh
  13. Zahid M, Rahman F, Chowdhury A, Rana SH, Ansaari S, Lim AK, et al.
    BMJ Open, 2025 Feb 25;15(2):e089007.
    PMID: 40000077 DOI: 10.1136/bmjopen-2024-089007
    INTRODUCTION: People with tuberculosis (TB) who continue to smoke are more likely to have poor health outcomes than those who quit. Established smoking cessation approaches such as mHealth may help patients with TB quit smoking. This paper summarises the methodology proposed to assess the effectiveness and cost-effectiveness of mTB-Tobacco (an mHealth intervention) in helping patients with TB stop smoking and have improved health outcomes.

    METHODS AND ANALYSIS: A two-arm, parallel, open-label, multicentre, cluster randomised, two-stage adaptive design trial is proposed to first evaluate the superiority of mTB-Tobacco, compared with usual care and then the non-inferiority of mTB-tobacco compared with face-to-face behaviour support. Study settings include TB treatment centres in Bangladesh and Pakistan. The study population includes adult patients, newly diagnosed (within 4 weeks) with pulmonary TB disease, daily smokers, willing to quit and have access to mobile phones. The primary outcome includes biochemically verified continuous smoking abstinence assessed at 6 months per Russell Standard. A generalised linear mixed-effects model will be used to assess the impact of mTB-Tobacco intervention on continuous outcomes, incorporating fixed effects for the intervention, random effects for clusters and relevant covariates. Cost-effectiveness analysis will be done to estimate the cost per quitter and cost per quality-adjusted life year gained, calculate the incremental cost-effectiveness ratios to establish the value for money for mTB-Tobacco.

    ETHICS AND DISSEMINATION: This trial will be conducted in compliance with International Council on Harmonisation - Good Clinical Practice guidelines and the Declaration of Helsinki. The study has been approved by the ethics committees of the University of Edinburgh Medical School Research Ethics Committee (EMREC) of UK, the Bangladesh Medical Research Council (BMRC) and the National Bioethics Committee (PMRC) of Pakistan. The results of this trial will be disseminated in peer-reviewed journals and presented in academic conferences.

    TRIAL REGISTRATION NUMBER: ISRCTN86971818 (https://doi.org/10.1186/ISRCTN86971818); pre-enrolment, submission date: 29 August 2023; registration date: 11 September 2023.

    Matched MeSH terms: Bangladesh
  14. Terao M, Akter S, Yasin MG, Nakao R, Kato H, Alam MZ, et al.
    Infect Genet Evol, 2015 Apr;31:53-60.
    PMID: 25620376 DOI: 10.1016/j.meegid.2015.01.011
    Babesia gibsoni is a tick-borne hemoprotozoan parasite of dogs that often causes fever and hemolytic illness. Detection of B. gibsoni has been predominantly reported in Asian countries, including Japan, Korea, Taiwan, Malaysia, Bangladesh and India. The present study shows the first molecular characterization of B. gibsoni detected from dogs in Bangladesh. Blood samples were collected on FTA® Elute cards from 50 stray dogs in Mymensingh District in Bangladesh. DNA eluted from the cards was subjected to nested PCR for the 18S rRNA gene of Babesia species. Approximately 800bp PCR products were detected in 15 of 50 dogs (30%). Based on restriction fragment length polymorphism (RFLP) and direct sequencing of the PCR products, all parasite isolates were identified as B. gibsoni. Furthermore, the BgTRAP (B. gibsoni thrombospondin-related adhesive protein) gene fragments were detected in 13 of 15 18S rRNA gene PCR positive blood samples. Phylogenetic analysis of the BgTRAP gene revealed that B. gibsoni parasites in Bangladesh formed a cluster, which was genetically different from other Asian B. gibsoni isolates. In addition, tandem repeat analysis of the BgTRAP gene clearly showed considerable genetic variation among Bangladeshi isolates. These results suggested that B. gibsoni parasites in a different genetic clade are endemic in dogs in Bangladesh. Further studies are required to elucidate the origin, distribution, vector and pathogenesis of B. gibsoni parasites circulating in dogs in Bangladesh.
    Matched MeSH terms: Bangladesh/epidemiology
  15. Hossain MG, Bharati P, Aik S, Lestrel PE, Abeer A, Kamarul T
    J Biosoc Sci, 2012 Jul;44(4):385-99.
    PMID: 22340969 DOI: 10.1017/S002193201200003X
    Body mass index (BMI) is a good indicator of nutritional status in a population. In underdeveloped countries like Bangladesh, this indicator provides a method that can assist intervention to help eradicate many preventable diseases. This study aimed to report on changes in the BMI of married Bangladeshi women who were born in the past three decades and its association with socio-demographic factors. Data for 10,115 married and currently non-pregnant Bangladeshi women were extracted from the 2007 Bangladesh Demographic and Health Survey (BDHS). The age range of the sample was 15-49 years. The mean BMI was 20.85 ± 3.66 kg/m(2), and a decreasing tendency in BMI was found among birth year cohorts from 1972 to 1992. It was found that the proportion of underweight females has been increasing in those born during the last 20 years of the study period (1972 to 1992). Body mass index increased with increasing age, education level of the woman and her husband, wealth index, age at first marriage and age at first delivery, and decreased with increasing number of ever-born children. Lower BMI was especially pronounced among women who were living in rural areas, non-Muslims, employed women, women not living with their husbands (separated) or those who had delivered at home or non-Caesarean delivery.
    Matched MeSH terms: Bangladesh/epidemiology
  16. Wkly. Epidemiol. Rec., 2010 Feb 19;85(8):64-7.
    PMID: 20210044
    Matched MeSH terms: Bangladesh/epidemiology
  17. Kaku Y
    Uirusu, 2004 Dec;54(2):237-42.
    PMID: 15745162
    Nipah virus (NiV), emerged in Peninsular Malaysia, caused an outbreak of severe febrile encephalitis in humans and respiratory diseases in pigs between 1998 and 1999. By May of 1999, the death of 105 humans and the culling of about 1.1 million pigs were reported. Fruitbats of Pteropid species were identified as the natural reservoir hosts. The epidemiological studies suggested that NiV was introduced into pig farms by fruitbats, and was than transmitted to humans (mainly pig farmers) and other animals such as dogs, cats and horses. In 2004, NiV reappeared in Bangladesh with greater lethality. In contrast to the Malaysia case, epidemiologic characteristics of this outbreak suggested the possibility of fruitbats-to-person, or person-to-person transmission. In this article, the epidemiological comparison between two outbreaks in Malaysia and Bangladesh, and the new-trends of virological studies of NiV will be discussed.
    Matched MeSH terms: Bangladesh/epidemiology
  18. Kamruzzaman M, Rabbani MG, Saw A, Sayem MA, Hossain MG
    BMC Womens Health, 2015;15:54.
    PMID: 26219633 DOI: 10.1186/s12905-015-0211-4
    Anemia is one of the most common public health problems globally, and high prevalence has been reported among women of reproductive age, especially in developing countries. This study was conducted to evaluate differentials in the prevalence of anemia among non-pregnant, ever-married women of reproductive age in Bangladesh, and to examine associations with demographic, socioeconomic, and nutritional factors.
    Matched MeSH terms: Bangladesh/epidemiology
  19. Hooper C, Debnath PP, Biswas S, van Aerle R, Bateman KS, Basak SK, et al.
    Viruses, 2020 10 02;12(10).
    PMID: 33023199 DOI: 10.3390/v12101120
    Mass mortalities of the larval stage of the giant freshwater prawn, Macrobrachium rosenbergii, have been occurring in Bangladesh since 2011. Mortalities can reach 100% and have resulted in an 80% decline in the number of hatcheries actively producing M. rosenbergii. To investigate a causative agent for the mortalities, a disease challenge was carried out using infected material from a hatchery experiencing mortalities. Moribund larvae from the challenge were prepared for metatranscriptomic sequencing. De novo virus assembly revealed a 29 kb single‑stranded positive-sense RNA virus with similarities in key protein motif sequences to yellow head virus (YHV), an RNA virus that causes mass mortalities in marine shrimp aquaculture, and other viruses in the Nidovirales order. Primers were designed against the novel virus and used to screen cDNA from larvae sampled from hatcheries in the South of Bangladesh from two consecutive years. Larvae from all hatcheries screened from both years were positive by PCR for the novel virus, including larvae from a hatchery that at the point of sampling appeared healthy, but later experienced mortalities. These screens suggest that the virus is widespread in M. rosenbergii hatchery culture in southern Bangladesh, and that early detection of the virus can be achieved by PCR. The hypothesised protein motifs of Macrobrachium rosenbergii golda virus (MrGV) suggest that it is likely to be a new species within the Nidovirales order. Biosecurity measures should be taken in order to mitigate global spread through the movement of post-larvae within and between countries, which has previously been linked to other virus outbreaks in crustacean aquaculture.
    Matched MeSH terms: Bangladesh/epidemiology
  20. Rafi A, Sayeed Z, Sultana P, Aik S, Hossain G
    BMC Health Serv Res, 2020 Jul 09;20(1):633.
    PMID: 32646521 DOI: 10.1186/s12913-020-05505-x
    BACKGROUND: Delayed hospital presentation is a hindrance to the optimum clinical outcome of modern therapies of Myocardial infarction (MI). This study aimed to investigate the significant factors associated with prolonged pre-hospital delay and the impact of this delay on in-hospital mortality among patients with MI in Northern Bangladesh.

    METHODS: This cross sectional study was conducted in December 2019 in cardiology ward of a 1000-bed tertiary care hospital of Bangladesh. Patients admitted in the ward with the diagnosis of myocardial infarction were included in the study. Socio demographic data, clinical features and patients' health seeking behavior was collected in a structured questionnaire from the patients. Median with interquartile range (IQR) of pre hospital delay were calculated and compared between different groups. Chi-square (χ2) test and binary logistic regression were used to estimate the determinants of pre-hospital delay and effect of pre-hospital delay on in-hospital mortality.

    RESULTS: Three hundred thirty-seven patients was enrolled in the study and their median (IQR) pre-hospital delay was 9.0 (13.0) hours. 39.5% patients admitted in the specialized hospital within 6 h. In logistic regression, determinants of pre-hospital delay were patients age (for

    Matched MeSH terms: Bangladesh/epidemiology
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