MyMedR

Displaying publications 1 - 20 of 220 in total

Abstract:

Sort:

Insects of Tasik Chini with special emphasis on Ichneumonid wasps

Idris A, Ismail S, Haron Y, Suhana Y

Sains Malaysiana, 2009;38.

A preliminary study on selected insect communities of Tasik Chini was conducted from 27th May to 2nd June 2004 along three trails namely trail to Sg. Gumum, trail to Kampung Melai and trail to old tin mining area. A total of eight Malaise traps were installed along the trail to Sg. Gumum while sweeping net and 10 yellow pan traps per trail were used to sample insects along the other two trails. A total of 502 insect individuals consisting of eight orders and 46 families were successfully collected. Of these, the hymenopterans (ants and wasps) had the most number (298 individuals and 11 families) while the Blattaria was the least number (six individuals and two families). Of the hymenopterans, the ichneumonids had the most individuals collected (52) followed by evaniid (50) and vespid wasps (41). For the Coleopterans, Cleridae were the most collected (26) during this short study followed by Anthribidae (13). There were 62 of individuals Odonata consisting of 9 species identified.
Inflammation of the Gums

Intan Suhana MA, Farha A, Hassan BM

Malays Fam Physician, 2020;15(1):71-73.
PMID: 32284812
Fulltext Ankle injuries in sports: anatomical considerations and clinical implications

Syarifah Aisyah, S.A.H., Elvy Suhana, M.R., Srijit, D., Norzana, A.G.

Medicine & Health, 2016;11(2):117-130.
MyJurnal

Ankle injuries are commonly seen in various sports. The main aim of the present
review was to highlight the normal anatomy of the ankle, mechanism of injuries
related to sports, congenital abnormalities or anatomical variations related to
ankle injury and discuss its effective management. A review of literature was done
to determine the ankle injuries which occur as a result of various sports related
activities. We documented all sports which involved injury to the ankle joint. The
anatomy of various structures in the sole of foot and their involvement in injuries
were discussed at length. The anatomical knowledge of ankle injury may be
beneficial for future diagnosis and treatment purpose.
Analysis of major fragrant compounds from Citrus grandis flowers extracts

Zarina Zakaria, Suhana Zakaria, Mohd Azlan Mohd Ishak

Sains Malaysiana, 2010;39.

Various sampling techniques such as hydrodistillation, Soxhlet extraction and solid phase micro extraction (SPME) were used to extract compounds, i.e. the active components attributed to fragrance of C. grandis flowers. Gas chromatograph mass spectrometry was then used to identify and quantify the active components obtained from the techniques. The results thus far showed that, buds and blossoms of this flower which possesses a strong floral-, jasmine- and orange-like aroma contain β-myrcene, limonene, ocimene, linalool and caryophyllene as the major compounds. In hydrodistillation technique the levels of ocimene and linalool detected in blossom were higher than in the bud at 7.37 and 15.93%, respectively, while in the bud, limonene was the highest, i.e. 4.57%. In Soxhlet extraction, however the bud was found to consist of limonene (27.25%), ocimene (5.55%) and linalool (2.97%). The performance of three available SPME fibers was compared to evaluate the recoveries of volatile compounds in C.grandis flowers and 100 μm polydimethylsiloxane was found to be the most effective.
Fulltext Common foot deformities among Malaysian women: wearing incorrectly sized shoes

Shaliza Mohd Shariff, Norazmi Shahlal, Suhana Japar, Asma Ahmad Sharif

Journal of Engineering and Science Research, 2019;3(3):28-32.
MyJurnal

Several foot deformities have been identified in Malaysian women due to wearing shoes which do not fit the size and shape of their feet. Hallux valgus (bunions), corn, cellules and ingrown toenail are among the common deformities experienced by Malaysian women. The root of this issue is that the Malaysian footwear market has adopted foreign shoe size standards such as those from the US and UK. This means that Malaysian women face difficulties in obtaining correctly-sized shoes. Therefore, the aim of this study is to develop and propose a standard shoe sizing system for women in Malaysia based on anthropometric measurements of Malaysian women’s foot sizes and shapes. Women from Malaysia’s primary ethnic groups (Malay, Chinese, and Indian) aged 20 to 60 years old participated in this project, where the anthropometric measurements for their foot size and shapes were obtained using a 3D foot scanner. Regression analysis in the form of Generalized Linear Model (GLM) was performed to determine the association between a few attributes including foot measurements and the existence of the foot deformities. Foot length and Ball girth circumference have significant association with the foot deformities (FL: p = .028 and BG: p = .045). The new standard shoe sizing system has been developed ith more accurate sizes and shapes, it is hoped that the foot deformities problem could be solved or at least reduced the foot pain.
Fulltext Relationship among obesity, physical activity level, physical fitness and academic performance in female secondary school students in Shah Alam

Nurul Amira Mohd Samsudin, Sarina Md. Yusof, Suhana Aiman

Movement Health & Exercise, 2019;8(1):81-89.
MyJurnal

The aim of this study was to determine the relationship among obesity, physical activity level, physical fitness and academic performance among female secondary school students in Shah Alam. Two hundred and fourteen participants (age: 16 years, body height: 156.76 ± 5.65 cm, body mass 59.92 ± 13.35 kg, BMI: 24.41 ± 5.00 kg/m2) participated in this study. Students with a body mass index above 25 kg/m2 were classified as obese. Physical activity level was evaluated by using International Physical Activity Questionnaire (IPAQ), while physical fitness was evaluated by the total score of four fitness components (cardiovascular endurance, muscular endurance, muscular strength, flexibility) measured by SEGAK used in Malaysia secondary schools. Academic performance was assessed by the Average School Grade (ASG) from the Form Three Assessment (PT3) results of the previous year. There was a negative significant relationship between obesity and physical activity level (r = -0.20, p < 0.05), obesity and physical fitness (r = -0.42, p < 0.05), obesity and academic performance (r = 0.49, p < 0.05), physical activity level and physical fitness (r = 0.54, p < 0.05), physical activity level and academic performance (r = -0.14, p < 0.05). and physical fitness and academic performance (r = -0.26, p < 0.05). These results suggested that obesity status, physical activity level and physical fitness could not only affect health status but also academic performance in secondary school students.
Anti-inflammatory effect of Curcuma longa (turmeric) on collagen-induced arthritis: an anatomico-radiological study

Taty Anna K, Elvy Suhana MR, Das S, Faizah O, Hamzaini AH

Clin Ter, 2011;162(3):201-7.
PMID: 21717043

Curcuma longa (CL) or turmeric is an Ayurvedic herb that has been traditionally used to treat inflammatory conditions like rheumatoid arthritis (RA). Collagen-induced arthritis (CIA) is a well established experimental auto-immune mediated polyarthritis in susceptible strains of rodents. The main aim of the study was to observe the inflammatory, macroscopic and radiological changes in the arthritic ankle joints of experimentally collagen-induced arthritis animals treated with or without CL extract.
Surgical outcomes of transmastoid facial nerve decompression: Preliminary data from a Malaysian tertiary hospital from 2013-2018

Siang PG, Ying XT, Dayang Suhana AM, Ing PT

Med J Malaysia, 2020 05;75(3):281-285.
PMID: 32467545

INTRODUCTIONS: Facial nerve palsy (FNP) occurs in 7-10% of temporal bone fractures. The aim of this study was to review the surgical outcome of nine patients with severe to complete traumatic facial nerve (FN) injury.
METHODS: The patients were evaluated clinically and FNP was graded using the House Brackmann (HB) scale. High resolution computerized tomography (HRCT) of the temporal bone was used to evaluate temporal bone fractures. Transmastoid facial nerve decompression was performed and the facial nerve function was re-evaluated in subsequent follow ups.
RESULTS: There were five cases with immediate onset and four with delayed onset of FNP. Only three cases had pure temporal bone fractures, the others were associated with other life threatening injuries. The sensitivity and specificity of HRCT temporal bone to detect the obvious facial canal fracture line were 50% and 40% respectively. 75% of patients with immediate onset of HB grade VI FN palsy who were operated within a month recovered completely. Surgeries for the delayed onset FNP were performed at a mean of 70 days (range 51-94). All recovered to HB grade II-III from severe FNP.
CONCLUSIONS: Our study demonstrated that transmastoid FN decompression surgery was beneficial to traumatic nerve injury. Early intervention resulted in better outcomes. However, FN function could still be salvaged even in delayed FN decompression.
Bluish swelling on the floor of the mouth

Hassan BM, Intan Suhana MA, Megat Mustaqim MI

Malays Fam Physician, 2020;15(1):64-67.
PMID: 32284810
Tobacco use disorder: Prevalence, associated factors and its influence on quality of life among patients on methadone assisted treatment

Moey CH, Yee A, Muhamud Kayat SB

J Addict Dis, 2020 04 24;38(3):263-270.
PMID: 32329412 DOI: 10.1080/10550887.2020.1748990

Background and Objectives: Smoking is the primary cause of preventable death and is highly prevalent among patients on methadone assisted treatment (MAT). This study aims to assess the prevalence of tobacco use disorder (TUD) among patients on MAT, the factors associated with TUD, and to examine the association between TUD and quality of life.Methods: A total of 171 male patients receiving MAT in two Malaysian government hospitals were assessed for TUD, levels of nicotine dependence, relevant associated factors and quality of life using DSM-5 criteria, Fagerström Test for Nicotine Dependence (FTND), Opiate Treatment Index (OTI), Mini-International Neuropsychiatric Interview (M.I.N.I.) and World Health Organization Quality of Life (WHOQOL)-BREF.Results: The prevalence of TUD was 81.3%. Being employed was significantly associated with having a TUD. Among the patients with TUD, the mean FTND score was 3.8 (SD ± 2.0). Being younger, having poorer social function, and presence of current opioid dependence were significantly correlated with higher FTND scores. There was no significant difference in the quality of life between patients with and without TUD. Following multiple linear regression analysis, being unmarried and poor health status were the two factors that significantly predicted a lower quality of life in all four domains of WHOQOL-BREF.Conclusions: Given the high prevalence of TUD among methadone-assisted patients, smoking cessation treatment should be integrated into the MAT program in Malaysia. Also, addressing patients' marital and health issues during MAT can be instrumental in improving their quality of life.
Blue phase liquid crystal: strategies for phase stabilization and device development

Rahman MD, Mohd Said S, Balamurugan S

Sci Technol Adv Mater, 2015 Jun;16(3):033501.
PMID: 27877782

The blue phase liquid crystal (BPLC) is a highly ordered liquid crystal (LC) phase found very close to the LC-isotropic transition. The BPLC has demonstrated potential in next-generation display and photonic technology due to its exceptional properties such as sub-millisecond response time and wide viewing angle. However, BPLC is stable in a very small temperature range (0.5-1 °C) and its driving voltage is very high (∼100 V). To overcome these challenges recent research has focused on solutions which incorporate polymers or nanoparticles into the blue phase to widen the temperature range from around few °C to potentially more than 60 °C. In order to reduce the driving voltage, strategies have been attempted by modifying the device structure by introducing protrusion or corrugated electrodes and vertical field switching mechanism has been proposed. In this paper the effectiveness of the proposed solution will be discussed, in order to assess the potential of BPLC in display technology and beyond.
Effect of Irradiating Puparia of Oriental Fruit Fly (Diptera: Tephritidae) on Adult Survival and Fecundity for Sterile Insect Technique and Quarantine Purposes

Yusof S, Mohamad Dzomir AZ, Yaakop S

J Econ Entomol, 2019 12 09;112(6):2808-2816.
PMID: 31393572 DOI: 10.1093/jee/toz217

The aim of this study was to investigate the effect of gamma irradiation on survivability (adult emergence, sex ratio, adult longevity), fecundity (eggs hatchability, number of eggs produced), and morphological differences in the size of the ovary and testes of unirradiated and irradiated adults of Oriental fruit fly [Bactrocera dorsalis (Hendel)]. A dose of 100 Gy was determined as the minimum needed for inhibitory effects against B. dorsalis that would not deter adult emergence, sex ratio (male:female), and adult longevity, with 82.6 ±7.02, 1:1.09, and 107 ± 24.5, respectively. Doses from 50 to 400 Gy range did not completely prevent the adult emergence; however, the emergence decreased by increasing the radiation dose. Adult survivability significantly decreased among all the treatment groups of B. dorsalis, except for the 50 Gy and unirradiated flies. At a dose of 50 Gy, fertile females showed a significant reduction in fecundity by not producing eggs after mating with the sterile males. Meanwhile, the number of eggs laid decreased with increasing dose and no fertile egg was hatched starting at 100 Gy of irradiation. Testes and ovaries of 20-d old flies irradiated as pupae were smaller than those of control flies. In this study, 100 Gy was concluded as the minimum effective dose for the disinfestation and sterilization of B. dorsalis puparia. Results represent new findings used as a basis for sterile insect technique and quarantine programs for managing B. dorsalis, particularly in Malaysia.
Targeting immunosuppressor cells with nanoparticles in autoimmunity: How far have we come to?

Ahmad S, Al-Hatamleh MAI, Mohamud R

Cell Immunol, 2021 10;368:104412.
PMID: 34340162 DOI: 10.1016/j.cellimm.2021.104412

Autoimmunity is the assault of immune response towards self-antigens, resulting to inflammation and tissue injury. It is staged into three phases and caused by malfunction of immune tolerance. In our body, immune tolerance is synchronized by several immunosuppressor cells such as regulatory T cells and B cells as well as myeloid-derived suppressor cells, which are prominently dysregulated in autoimmunity. Hence, targeting these cell populations serve as a significant potential in the therapy of autoimmunity. Nanotechnology with its advantageous properties is shown to be a remarkable tool as drug delivery system in this field. This review focused on the development of therapeutics in autoimmune diseases utilizing various nanoparticles formulation based on two targeting approaches in autoimmunity, passive and active targeting. Lastly, this review outlined the approved present nanomedicines as well as in clinical evaluations and issues regarding the lack of translation of these nanomedicines into the market, despite the abundant of positive experimental observations.
Gelam honey attenuates ovalbumin-induced airway inflammation in a mice model of allergic asthma

Shamshuddin NSS, Mohd Zohdi R

J Tradit Complement Med, 2018 Jan;8(1):39-45.
PMID: 29321987 DOI: 10.1016/j.jtcme.2016.08.009

Allergic asthma is a chronic inflammatory disorder of the pulmonary airways. Gelam honey has been proven to possess anti-inflammatory property with great potential to treat an inflammatory condition. However, the effect of ingestion of Gelam honey on allergic asthma has never been studied. This study aimed to investigate the efficacy of Gelam honey on the histopathological changes in the lungs of a mice model of allergic asthma. Forty-two Balb/c mice were divided into seven groups: control, I, II, III, IV, V and VI group. All groups except the control were sensitized and challenged with ovalbumin. Mice in groups I, II, III, IV, and V were given honey at a dose of 10% (v/v), 40% (v/v) and 80% (v/v), dexamethasone 3 mg/kg, and phosphate buffered saline (vehicle) respectively, orally once a day for 5 days of the challenged period. Mice were sacrificed 24 h after the last OVA challenged and the lungs were evaluated for histopathological changes by light microscopy. All histopathological parameters such as epithelium thickness, the number of mast cell and mucus expression in Group III significantly improved when compared to Group VI except for subepithelial smooth muscle thickness (p
Oral healthcare seeking behavior of Malaysian adults in urban and rural areas: findings from the National Health and Morbidity Survey 2019

Tan YR, Jawahir S, Doss JG

BMC Oral Health, 2023 Oct 05;23(1):719.
PMID: 37798660 DOI: 10.1186/s12903-023-03470-5

BACKGROUND: The development and implementation of appropriate strategies to enhance oral health in the community can be aided by an understanding of oral healthcare seeking behavior among urban and rural populations. The purpose of this study was to identify the factors associated with oral healthcare seeking behavior of the Malaysians in urban and rural locations who self-reported dental problems.
METHODS: The National Health and Morbidity Survey 2019, a cross-sectional nationwide household survey that focused on non-institutionalised Malaysians, provided the data for this study on adults in Malaysia who were 18 years of age and older. A two-stage stratified random sampling technique was employed to ensure national representativeness. Data was collected using a multilingual (Malay and English), structured, and validated questionnaire via face-to-face interviews from July to October 2019. The dependent variable was oral healthcare seeking behavior (sought oral healthcare and self-medication). Independent variables were predisposing, enabling and health needs factor based on Andersen's Behavioral Model. Descriptive statistics were used to describe the characteristics and oral healthcare seeking behavior of the respondents. The relationship between the independent and dependent variables were investigated using multivariable logistic regression analysis.
RESULTS: The analysis comprised a total of 10,134 respondents, representing about 18.2 million Malaysian adults aged 18 and above. The overall prevalence of Malaysian adults who self-reported dental problems was low (5.5%) and was slightly higher in the rural than urban population. Almost half sought treatment from healthcare practitioners, and almost a quarter self-medicated. Ethnicity was associated with seeking healthcare and self-medication among urban dwellers. Among the rural population, income level was associated with seeking healthcare while education level was associated with self-medication.
CONCLUSION: Disparities in oral healthcare seeking behaviors exist between Malaysians living in urban and rural areas. Future policies should adopt focused strategies that concentrate on oral healthcare accessibility and health literacy of the vulnerable and rural populations to achieve the best oral healthcare for this population group.
Fulltext Mol-ecular structure, DFT studies and Hirshfeld analysis of anthracenyl chalcone derivatives

Zainuri DA, Razak IA, Arshad S

Acta Crystallogr E Crystallogr Commun, 2018 Jun 01;74(Pt 6):780-785.
PMID: 29951229 DOI: 10.1107/S2056989018006527

The mol-ecular and crystal structure of two new chalcone derivatives, (E)-1-(anthracen-9-yl)-3-[4-(piperidin-1-yl)phen-yl]prop-2-en-1-one, C28H25NO, (I), and (E)-1-(anthracen-9-yl)-3-[4-(di-phenyl-amino)-phen-yl]prop-2-en-1-one, C35H25NO, (II), with the fused-ring system at the same position are described. In the crystals of (I) and (II), the mol-ecules are linked via C-H⋯O hydrogen bonds into inversion dimers, forming R22(22) and R22(14) ring motifs, respectively. Weak inter-molecular C-H⋯π inter-actions further help to stabilize the crystal structure, forming a two-dimensional architecture. The mol-ecular structures are optimized using density functional theory (DFT) at B3LYP/6-311 G++(d,p) level and compared with the experimental results. The smallest HOMO-LUMO energy gaps of (I) (exp . 2.76 eV and DFT 3.40 eV) and (II) (exp . 2.70 eV and DFT 3.28 eV) indicates the suitability of these crystals in optoelectronic applications. All inter-molecular contacts and weaker contributions involved in the supra-molecular stabilization are investigated using Hirshfeld surface analysis. The mol-ecular electrostatic potential (MEP) further identifies the positive, negative and neutral electrostatic potential regions of the mol-ecules.
Fulltext The effect of the fused-ring substituent on anthracene chalcones: crystal structural and DFT studies of 1-(anthracen-9-yl)-3-(naphthalen-2-yl)prop-2-en-1-one and 1-(anthracen-9-yl)-3-(pyren-1-yl)prop-2-en-1-one

Zainuri DA, Razak IA, Arshad S

Acta Crystallogr E Crystallogr Commun, 2018 May 01;74(Pt 5):650-655.
PMID: 29850084 DOI: 10.1107/S2056989018005467

The title chalcone compounds, C27H18O (I) and C33H20O (II), were synthesized using a Claisen-Schmidt condensation. Both compounds display an s-trans configuration of the enone moiety. The crystal structures feature inter-molecular C-H⋯O and C-H⋯π inter-actions. Quantum chemical analysis of density functional theory (DFT) with a B3LYP/6-311++G(d,p) basis set has been employed to study the structural properties of the compound. The effect of the inter-molecular inter-actions in the solid state are responsible for the differences between the experimental and theoretical optimized geometrical parameters. The small HOMO-LUMO energy gap in (I) (exp : 3.18 eV and DFT: 3.15 eV) and (II) (exp : 2.76 eV and DFT: 2.95 eV) indicates the suitability of these compounds for optoelectronic applications. The inter-molecular contacts and weak contributions to the supra-molecular stabilization are analysed using Hirshfeld surface analysis.
Fulltext (E)-1,3-Bis(anthracen-9-yl)prop-2-en-1-one: crystal structure and DFT study

Zainuri DA, Razak IA, Arshad S

Acta Crystallogr E Crystallogr Commun, 2018 Apr 01;74(Pt 4):492-496.
PMID: 29765753 DOI: 10.1107/S2056989018003791

The title compound, C31H20O, was synthesized using a Claisen-Schmidt condensation. The enone group adopts an s-trans conformation and the anthracene ring systems are twisted at angles of 85.21 (19) and 83.98 (19)° from the enone plane. In the crystal, mol-ecules are connected into chains along [100] via weak C-H⋯π inter-actions. The observed band gap of 3.03 eV is in excellent agreement with that (3.07 eV) calculated using density functional theory (DFT) at the B3LYP/6-311++G(d,p) level. The Hirshfeld surface analysis indicates a high percentage of C⋯H/H⋯C (41.2%) contacts in the crystal.
Fulltext Crystal structures, DFT studies and UV-visible absorption spectra of two anthracenyl chalcone derivatives

Zainuri DA, Razak IA, Arshad S

Acta Crystallogr E Crystallogr Commun, 2018 Oct 01;74(Pt 10):1491-1496.
PMID: 30319808 DOI: 10.1107/S2056989018013087

The crystal structures of (E)-1-(anthracen-9-yl)-3-(3H-indol-2-yl)prop-2-en-1-one, C25H17NO, and (E)-1-(anthracen-9-yl)-3-[4-(di-methyl-amino)-naphthalen-1-yl]prop-2-en-1-one, C29H23NO, are reported. In each case the anthracene ring system and pendant ring system are almost perpendicular to each other [dihedral angles = 75.57 (7)° and 70.26 (10)°, respectively]. In the extended structures, weak N-H⋯O, C-H⋯O and C-H⋯π inter-actions influence the centrosymmetric crystal packing. Density functional theory calculations were carried out using a 6-311 G++(d,p) basis set and the calculated structures are in good agreement with the crystal structures. The compounds were also characterized by UV-Vis absorption spectroscopy and the smallest (HOMO-LUMO) energy gaps of 2.89 and 2.54 eV indicate the enhanced non-linear responses (inter-molecular charge transfers) of these systems.
Fulltext Crystal structure, spectroscopic characterization and DFT study of two new linear fused-ring chalcones

Zainuri DA, Razak IA, Arshad S

Acta Crystallogr E Crystallogr Commun, 2018 Oct 01;74(Pt 10):1427-1432.
PMID: 30319794 DOI: 10.1107/S2056989018012641

The structures of two new anthracenyl chalcones, namely (E)-1-(anthracen-9-yl)-3-(4-nitro-phen-yl)prop-2-en-1-one, C23H15NO3, and (E)-1-(anthracen-9-yl)-3-(4-iodo-phen-yl)prop-2-en-1-one, C23H15IO are reported. A structural comparative study between the two chalcones was performed and some effects on the geometrical parameters, such as planarity and dihedral angles, are described. The mol-ecular geometry was determined by single-crystal X-ray diffraction, and density functional theory (DFT) at B3LYP with the 6-311++G(d,p) basis set was applied to optimize the ground-state geometry. In addition, inter-molecular inter-actions responsible for the crystal packing were analysed. The electronic properties, such as excitation energies and HOMO-LUMO energies were calculated by time-dependent density functional theory (TD-DFT) and the results complement the experimental findings. The mol-ecular electrostatic potential (MEP) was also investigated at the same level of theory in order to identify and qu-antify the possible reactive sites.

Filters

Please provide feedback to Administrator (afdal@afpm.org.my)

External Links