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Fulltext The presence of microplastics in commercial salts from different countries

Karami A, Golieskardi A, Keong Choo C, Larat V, Galloway TS, Salamatinia B

Sci Rep, 2017 04 06;7:46173.
PMID: 28383020 DOI: 10.1038/srep46173

The occurrence of microplastics (MPs) in saltwater bodies is relatively well studied, but nothing is known about their presence in most of the commercial salts that are widely consumed by humans across the globe. Here, we extracted MP-like particles larger than 149 μm from 17 salt brands originating from 8 different countries followed by the identification of their polymer composition using micro-Raman spectroscopy. Microplastics were absent in one brand while others contained between 1 to 10 MPs/Kg of salt. Out of the 72 extracted particles, 41.6% were plastic polymers, 23.6% were pigments, 5.50% were amorphous carbon, and 29.1% remained unidentified. The particle size (mean ± SD) was 515 ± 171 μm. The most common plastic polymers were polypropylene (40.0%) and polyethylene (33.3%). Fragments were the primary form of MPs (63.8%) followed by filaments (25.6%) and films (10.6%). According to our results, the low level of anthropogenic particles intake from the salts (maximum 37 particles per individual per annum) warrants negligible health impacts. However, to better understand the health risks associated with salt consumption, further development in extraction protocols are needed to isolate anthropogenic particles smaller than 149 μm.

Matched MeSH terms: Salts/chemistry*
Fulltext Influence of Salts on the Photocatalytic Degradation of Formic Acid in Wastewater

Che Abdul Rahim AN, Yamada S, Bonkohara H, Mestre S, Imai T, Hung YT, et al.

Int J Environ Res Public Health, 2022 Nov 26;19(23).
PMID: 36497814 DOI: 10.3390/ijerph192315736

Conventional wastewater treatment technologies have difficulties in feasibly removing persistent organics. The photocatalytic oxidation of these contaminants offers an economical and environmentally friendly solution. In this study, TiO2 membranes and Ag/TiO2 membranes were prepared and used for the decomposition of dissolved formic acid in wastewater. The photochemical deposition of silver on a TiO2 membrane improved the decomposition rate. The rate doubled by depositing ca. 2.5 mg of Ag per 1 g of TiO2. The influence of salinity on formic acid decomposition was studied. The presence of inorganic salts reduced the treatment performance of the TiO2 membranes to half. Ag/TiO2 membranes had a larger reduction of ca. 40%. The performance was recovered by washing the membranes with water. The anion adsorption on the membrane surface likely caused the performance reduction.

Matched MeSH terms: Salts*
Fulltext Influence of organic molecules on wetting characteristics of mica/H2/brine systems: Implications for hydrogen structural trapping capacities

Ali M, Yekeen N, Pal N, Keshavarz A, Iglauer S, Hoteit H

J Colloid Interface Sci, 2022 Feb 15;608(Pt 2):1739-1749.
PMID: 34742087 DOI: 10.1016/j.jcis.2021.10.080

HYPOTHESIS: Actualization of the hydrogen (H2) economy and decarbonization goals can be achieved with feasible large-scale H2 geo-storage. Geological formations are heterogeneous, and their wetting characteristics play a crucial role in the presence of H2, which controls the pore-scale distribution of the fluids and sealing capacities of caprocks. Organic acids are readily available in geo-storage formations in minute quantities, but they highly tend to increase the hydrophobicity of storage formations. However, there is a paucity of data on the effects of organic acid concentrations and types on the H2-wettability of caprock-representative minerals and their attendant structural trapping capacities.
EXPERIMENT: Geological formations contain organic acids in minute concentrations, with the alkyl chain length ranging from C4 to C26. To fully understand the wetting characteristics of H2 in a natural geological picture, we aged mica mineral surfaces as a representative of the caprock in varying concentrations of organic molecules (with varying numbers of carbon atoms, lignoceric acid C24, lauric acid C12, and hexanoic acid C6) for 7 days. To comprehend the wettability of the mica/H2/brine system, we employed a contact-angle procedure similar to that in natural geo-storage environments (25, 15, and 0.1 MPa and 323 K).
FINDINGS: At the highest investigated pressure (25 MPa) and the highest concentration of lignoceric acid (10-2 mol/L), the mica surface became completely H2 wet with advancing (θa= 106.2°) and receding (θr=97.3°) contact angles. The order of increasing θa and θr with increasing organic acid contaminations is as follows: lignoceric acid > lauric acid > hexanoic acid. The results suggest that H2 gas leakage through the caprock is possible in the presence of organic acids at higher physio-thermal conditions. The influence of organic contamination inherent at realistic geo-storage conditions should be considered to avoid the overprediction of structural trapping capacities and H2 containment security.

Matched MeSH terms: Salts
Natural dead sea salt and retrospective dosimetry

Wahib NB, Abdul Sani SF, Ramli A, Ismail SS, Abdul Jabar MH, Khandaker MU, et al.

Radiat Environ Biophys, 2020 08;59(3):523-537.
PMID: 32462382 DOI: 10.1007/s00411-020-00846-x

Accidents resulting in widespread dispersal of radioactive materials have given rise to a need for materials that are convenient in allowing individual dose assessment. The present study examines natural Dead Sea salt adopted as a model thermoluminescence dosimetry system. Samples were prepared in two different forms, loose-raw and loose-ground, subsequently exposed to 60Co gamma-rays, delivering doses in the range 2-10 Gy. Key thermoluminescence (TL) properties were examined, including glow curves, dose response, sensitivity, reproducibility and fading. Glow curves shapes were found to be independent of given dose, prominent TL peaks for the raw and ground samples appearing in the temperature ranges 361-385 ºC and 366-401 ºC, respectively. The deconvolution of glow curves has been undertaken using GlowFit, resulting in ten overlapping first-order kinetic glow peaks. For both sample forms, the integrated TL yield displays linearity of response with dose, the loose-raw salt showing some 2.5 × the sensitivity of the ground salt. The samples showed similar degrees of fading, with respective residual signals 28 days post-irradiation of 66% and 62% for the ground and raw forms respectively; conversely, confronted by light-induced fading the respective signal losses were 62% and 80%. The effective atomic number of the Dead Sea salt of 16.3 is comparable to that of TLD-200 (Zeff 16.3), suitable as an environmental radiation monitor in accident situations but requiring careful calibration in the reconstruction of soft tissue dose (soft tissue Zeff 7.2). Sample luminescence studies were carried out via Raman and Photoluminescence spectroscopy as well as X-ray diffraction, ionizing radiation dependent variation in lattice structure being found to influence TL response.

Matched MeSH terms: Salts*
Thermal properties analysis and thermal cycling of HITEC molten salt with h-BN nanoparticles for CSP thermal energy storage applications

Suraparaju SK, Aljaerani HA, Samykano M, Kadirgama K, Noor MM, Natarajan SK

Environ Sci Pollut Res Int, 2024 Aug;31(38):50166-50178.
PMID: 38625473 DOI: 10.1007/s11356-024-33151-x

Molten salts are the operational fluid for most concentrated solar power (CSP) systems, which has attracted more attention among the scientific community due to the augmentation of their properties with the doping of nanoparticles. Hexagonal boron nitride (h-BN) nanoparticles were dispersed in HITEC molten salt to create a novel nanofluid and evaluate the h-BN nanoparticles' influence on HITEC thermophysical properties. The influence of nanoparticle concentration (0.1, 0.5, and 1wt.%) of h-BN and HITEC was studied in this research. HITEC and nano-enhanced HITEC molten salt (NEHMS) were characterized using energy-dispersive X-ray spectroscopy (EDX), field emission scanning electron microscopy (FESEM), and Fourier transform infrared spectroscopy (FT-IR). Specific heat capacity, latent heat, and melting temperature were assessed using differential scanning calorimetry (DSC). The maximum working temperature was evaluated with thermogravimetric analysis (TGA). The ideal nanoparticle concentration is 0.1 wt.% h-BN, which results in a 27% increase in heat capacity, a 72% increase in latent heat, and a 7% enhancement in thermal stability. The thermal cycling stability test proved the stability of the enhanced thermophysical properties. The material characterization revealed that the samples with improved thermophysical properties have a homogeneous dispersion of nanoparticles with minor nanoparticle agglomeration. The system advisor model (SAM) simulation comparison of the optimum sample with solar salt and HITEC salt revealed that using the optimum sample increases CSP plant efficiency by 0.4% and reduces power costs by 0.13¢/kWh.

Matched MeSH terms: Salts/chemistry
Fulltext Emerging Two-Dimensional Crystallization of Cucurbit[8]uril Complexes: From Supramolecular Polymers to Nanofibers

Barrio JD, Liu J, Brady RA, Tan CSY, Chiodini S, Ricci M, et al.

J Am Chem Soc, 2019 09 11;141(36):14021-14025.
PMID: 31422657 DOI: 10.1021/jacs.9b07506

The binding of imidazolium salts to cucurbit[8]uril, CB[8], triggers a stepwise self-assembly process with semiflexible polymer chains and crystalline nanostructures as early- and late-stage species, respectively. In such a process, which involves the crystallization of the host-guest complexes, the guest plays a critical role in directing self-assembly toward desirable morphologies. These include platelet-like aggregates and two-dimensional (2D) fibers, which, moreover, exhibit viscoelastic and lyotropic properties. Our observations provide a deeper understanding of the self-assembly of CB[8] complexes, with fundamental implications in the design of functional 2D systems and crystalline materials.

Matched MeSH terms: Salts
Acetic acid as a protic solvent for reducing sulphuric acid concentrations in the production of cellulose nanocrystals alongside transition metal co-catalysts

Lim CSS, Chan EWC, Wong CW

Int J Biol Macromol, 2024 Feb;259(Pt 2):129303.
PMID: 38216018 DOI: 10.1016/j.ijbiomac.2024.129303

Cellulose nanocrystals (CNC) conventionally involve highly concentrated sulphuric acid, which typically resulted in the formation of undesirable by-products. Although less corrosive mineral acids have been explored as alternatives, high concentrations are still required. In this study, CNC was successfully isolated from Leucaena leucocephala wood using mild sulphuric acid with acetic acid as protic solvent, and it was further studied with the addition of Lewis acids in the form of multivalent transition metal salts as co-catalyst. Selected divalent and trivalent transition metal salts including (Cr(NO3)3, Fe(NO3)3, Co(NO3)2, and Ni(NO3)2) were investigated. The morphology, chemical structure, particle size, and physicochemical properties of the CNCs were determined. Controlled depolymerization of cellulose was observed using transmission electron microscopy (TEM). Rod-like morphology for all CNCs was obtained during the hydrolysis process with the smallest CNC particles found at an average length of 278.1 ± 35.1 nm and a diameter of 13.4 ± 3.0 nm. The results showed that higher valence state metal ions resulted in better cellulose hydrolysis efficiency. In addition, the use of transition metal salt as a co-catalyst improved production efficiency and minimised carbonization of CNC while maintaining desired crystallinity and thermal properties.

Matched MeSH terms: Salts
Optimization of C50 Carotenoids Production by Open Fermentation of Halorubrum sp. HRM-150

Ma YC, Gao MR, Yang H, Jiang JY, Xie W, Su WP, et al.

Appl Biochem Biotechnol, 2023 Jun;195(6):3628-3640.
PMID: 36648604 DOI: 10.1007/s12010-023-04319-x

C50 carotenoids, as unique bioactive molecules, have many biological properties, including antioxidant, anticancer, and antibacterial activity, and have a wide range of potential uses in the food, cosmetic, and biomedical industries. The majority of C50 carotenoids are produced by the sterile fermentation of halophilic archaea. This study aims to look at more cost-effective and manageable ways of producing C50 carotenoids. The basic medium, carbon source supplementation, and optimal culture conditions for Halorubrum sp. HRM-150 C50 carotenoids production by open fermentation were examined in this work. The results indicated that Halorubrum sp. HRM-150 grown in natural brine medium grew faster than artificial brine medium. The addition of glucose, sucrose, and lactose (10 g/L) enhanced both biomass and carotenoids productivity, with the highest level reaching 4.53 ± 0.32 μg/mL when glucose was added. According to the findings of orthogonal studies based on the OD600 and carotenoids productivity, the best conditions for open fermentation were salinity 20-25%, rotation speed 150-200 rpm, and pH 7.0-8.2. The up-scaled open fermentation was carried out in a 7 L medium under optimum culture conditions. At 96 h, the OD600 and carotenoids productivity were 9.86 ± 0.51 (dry weight 10.40 ± 1.27 g/L) and 7.31 ± 0.65 μg/mL (701.40 ± 21.51 μg/g dry weight, respectively). When amplified with both universal bacterial primer and archaeal primer in the open fermentation, Halorubrum remained the dominating species, indicating that contamination was kept within an acceptable level. To summarize, open fermentation of Halorubrum is a promising method for producing C50 carotenoids.

Matched MeSH terms: Salts
The role of alternative salt bridges in cold adaptation of a novel psychrophilic laminarinase

Parvizpour S, Razmara J, Shamsir MS, Illias RM, Abdul Murad AM

J Biomol Struct Dyn, 2017 06;35(8):1685-1692.
PMID: 27206405 DOI: 10.1080/07391102.2016.1191043
Matched MeSH terms: Salts/chemistry
Salted fish and nasopharyngeal carcinoma in Malaysia

Armstrong RW, Eng AC

Soc Sci Med, 1983;17(20):1559-67.
PMID: 6635717 DOI: 10.1016/0277-9536(83)90100-4

The evidence for a hypothesis that eating salted fish is associated with nasopharyngeal carcinoma (NPC) is reviewed. The hypothesis was tested among Malaysian Chinese using a matched case-control design. The kinds of salted fish and patterns of use were also investigated in a control group comprising 100 Chinese, 50 Malay and 50 Indian households. During 1980, in Selangor, Malaysia, interviews with 100 Chinese cases of NPC and 100 non-disease controls indicated that salted fish consumption during childhood was a significant risk (relative risk = 3.0, P = 0.04), with an elevated risk for daily as opposed to less frequent consumption. Salted fish consumption during adolescence was a less significant risk, and current consumption not at all. There were 19 kinds of fishes reported as being eaten as salted fish by the 200 control households. There were marked differences between ethnic groups in preference for different kinds: Chinese preferred red snapper (74% of households), Malay jewfish (54%) and Indian red snapper (28%). Salted fish was hardly ever eaten daily by any household; weekly was a moderate frequency in all ethnic groups; less than weekly most common. There were no statistically significant differences between Chinese NPC case and non-disease control participants in kind of salted fish eaten. Results were the same when the data were analyzed by sex, subethnic group and income.

Matched MeSH terms: Salts/adverse effects*
Clinical evaluation of dactilase: a eutonic preparation for the treatment of digestive disorders

Jefferson NC

Med J Malaya, 1967 Jun;21(4):322-5.
PMID: 4230499
Matched MeSH terms: Bile Acids and Salts/therapeutic use*
Fulltext Kinetics Study of Microwave-Assisted Brine Extraction of Lipid from the Microalgae Nannochloropsis sp

Zghaibi N, Omar R, Kamal SMM, Biak DRA, Harun R

Molecules, 2020 Feb 12;25(4).
PMID: 32059440 DOI: 10.3390/molecules25040784

The kinetics of lipid extraction utilizing microwave-assisted extraction (MAE) from Nannochloropsis sp. microalgae were studied using a low cost and green solvent, namely brine (NaCl) solution. The kinetic modelling of the lipid extraction was performed to evaluate the mechanism of the lipid mass transfer using different extraction models, including Fick's Law, First and Second-order Rate Law and the Patricelli mathematical model. The Patricelli mathematical model described the kinetics of lipid extraction well, with the highest average values of determination coefficient (R2 ≥ 0.952) and the lowest average values of mean relative percentage deviation (MRPD ≤ 8.666%). The lipid analysis indicated a positive influence of the microwave temperature and time on the quantity and quality of extracted lipids. SEM analysis of spent microalgae clearly shows an increase in the distorted cell with increase microwave temperature and time, which could be directly correlated to the mechanism of the MAE-brine technique.

Matched MeSH terms: Salts/chemistry*
Purification of exopolysaccharide produced from Lactobacillus spp. using ionic-liquid as adjuvant in alcohol/salt-based aqueous two-phase system for its antidiabetic properties

Raj ST, Puspanadan S, Gan CY, Tan JS

Int J Biol Macromol, 2024 May;267(Pt 2):131376.
PMID: 38608981 DOI: 10.1016/j.ijbiomac.2024.131376

Diabetes is a chronic, metabolic disease characterized by hyperglycemia resulting from either insufficient insulin production or impaired cellular response to insulin. Exopolysaccharides (EPS) produced by Lactobacillus spp. demonstrated promising therapeutic potential in terms of their anti-diabetic properties. Extraction and purification of EPS produced by Lactobacillus acidophilus and Limosilactobacillus reuteri were performed using ethanol precipitation, followed by alcohol/salt based aqueous two-phase system (ATPS). The purification process involved ethanol precipitation followed by an alcohol/salt-based ATPS. The study systematically investigated various purification parameters in ATPS, including ethanol concentration, type and concentration of ionic liquid, type and concentration of salt and pH of salt. Purified EPS contents from L. acidophilus (63.30 μg/mL) and L. reuteri (146.48 μg/mL) were obtained under optimum conditions of ATPS which consisted of 30 % (w/w) ethanol, 25 % (w/w) dipotassium hydrogen phosphate at pH 10 and 2 % (w/w) 1-butyl-3-methylimidazolium octyl sulfate. The extracted EPS content was determined using phenol sulphuric acid method. In α-amylase inhibition tests, the inhibitory rate was found to be 92.52 % (L. reuteri) and 90.64 % (L. acidophilus), while in α-glucosidase inhibition tests, the inhibitory rate was 73.58 % (L. reuteri) and 68.77 % (L. acidophilus), based on the optimized parameters selected in ATPS. These results suggest that the purified EPS derived from the postbiotics of Lactobacillus spp. hold promise as potential antidiabetic agents.

Matched MeSH terms: Salts/chemistry
Fulltext Discovery of Amide-Functionalized Benzimidazolium Salts as Potent α-Glucosidase Inhibitors

Khan IA, Ahmad M, Ashfaq UA, Sultan S, Zaki MEA

Molecules, 2021 Aug 06;26(16).
PMID: 34443347 DOI: 10.3390/molecules26164760

α-Glucosidase inhibitors (AGIs) are used as medicines for the treatment of diabetes mellitus. The α-Glucosidase enzyme is present in the small intestine and is responsible for the breakdown of carbohydrates into sugars. The process results in an increase in blood sugar levels. AGIs slow down the digestion of carbohydrates that is helpful in controlling the sugar levels in the blood after meals. Among heterocyclic compounds, benzimidazole moiety is recognized as a potent bioactive scaffold for its wide range of biologically active derivatives. The aim of this study is to explore the α-glucosidase inhibition ability of benzimidazolium salts. In this study, two novel series of benzimidazolium salts, i.e., 1-benzyl-3-{2-(substituted) amino-2-oxoethyl}-1H-benzo[d]imidazol-3-ium bromide 9a-m and 1-benzyl-3-{2-substituted) amino-2-oxoethyl}-2-methyl-1H-benzo[d] imidazol-3-ium bromide 10a-m were screened for their in vitro α-glucosidase inhibitory potential. These compounds were synthesized through a multistep procedure and were characterized by 1H-NMR, 13C-NMR, and EI-MS techniques. Compound 10d was identified as the potent α-glucosidase inhibitor among the series with an IC50 value of 14 ± 0.013 μM, which is 4-fold higher than the standard drug, acarbose. In addition, compounds 10a, 10e, 10h, 10g, 10k, 10l, and 10m also exhibited pronounced potential for α-glucosidase inhibition with IC50 value ranging from 15 ± 0.037 to 32.27 ± 0.050 µM when compared with the reference drug acarbose (IC50 = 58.8 ± 0.12 μM). A molecular docking study was performed to rationalize the binding interactions of potent inhibitors with the active site of the α-glucosidase enzyme.

Matched MeSH terms: Salts/chemistry
Waste newspaper as cellulose resource of activated carbon by sodium salts for methylene blue and congo red removal

Hao YS, Othman N, Zaini MAA

Int J Biol Macromol, 2024 Oct;277(Pt 4):134353.
PMID: 39089559 DOI: 10.1016/j.ijbiomac.2024.134353

The work was aimed at evaluating the adsorptive properties of waste newspaper (WN) activated carbons chemically produced using sodium salts for methylene blue (MB) and congo red (CR) removal. The activated carbons, designated as AC1, AC2, AC3 and AC4 were prepared through impregnation with NaH2PO4, Na2CO3, NaCl and NaOH, respectively and activation at 500 °C for 1 h. The activated carbons were characterized for surface chemistry, thermal stability, specific area, morphology and composition. The AC1 with a surface area of 917 m2/g exhibits a greater MB capacity of 651 mg/g. Meanwhile, a greater CR capacity was recorded by AC2 at 299 mg/g. The pseudo-second order model fitted well with the kinetic data, while the equilibrium data could be described by Langmuir model. The thermodynamic parameters, i.e.., positive ΔH°, negative ΔG° and positive ΔS° suggest that the adsorption of dyes is endothermic, spontaneous and feasible at high solution temperature. To conclude, WN is a potential cellulose source for producing activated carbon, while NaH2PO4 activation could be employed to convert WN into activated carbon for effective dye wastewater treatment.

Matched MeSH terms: Salts/chemistry
Clathration of Two-Dimensional Coordination Polymers: Synthesis and Structures of [M(4,4'-bpy)(2)(H(2)O)(2)](ClO(4))(2).(2,4'-bpy)(2).H(2)O and [Cu(4,4'-bpy)(2)(H(2)O)(2)](ClO(4))(4).(4,4'-H(2)Bpy) (M = Cd(II), Zn(II) and bpy = Bipyridine)

Tong ML, Ye BH, Cai JW, Chen XM, Ng SW

Inorg Chem, 1998 Jun 01;37(11):2645-2650.
PMID: 11670398

In the presence of guest 2,4'-bpy molecules or under acidic conditions, three compounds, [Cd(4,4'-bpy)(2)(H(2)O)(2)](ClO(4))(2).(2,4'-bpy)(2).H(2)O (1), [Zn(4,4'-bpy)(2)(H(2)O)(2)](ClO(4))(2).(2,4'-bpy)(2).H(2)O (2), and [Cu(4,4'-bpy)(2)(H(2)O)(2)](ClO(4))(4).(4,4'-H(2)bpy) (3), were obtained from the reactions of the metal salts and 4,4'-bpy in an EtOH-H(2)O mixture. 1 has a 2-D square-grid network structure, crystallizing in the monoclinic space group P2/n, with a = 13.231(3) Å, b = 11.669(2) Å, c = 15.019(3) Å, beta = 112.82(3) degrees, Z = 2; 2 is isomorphous with 1, crystallizing in the monoclinic space group P2/n, with a = 13.150(3) Å, b = 11.368(2) Å, c = 14.745(3) Å, beta = 110.60(3) degrees, Z = 2. The square grids superpose on each other into a channel structure, in which each layer consists of two pairs of shared edges, perfectly square-planar with an M(II) ion and a 4,4'-bpy at each corner and side, respectively. The square cavity has dimensions of 11.669(2) x 11.788(2) and 11.368(2) x 11.488(2) Å for 1 and 2, respectively. Every two guest 2,4'-bpy molecules are clathrated in each hydrophobic host cavity and are further stabilized by pi-pi stacking and hydrogen bonding interactions. The NMR spectra clearly confirm that both 1 and 2 contain 4,4'-bpy and 2,4'-bpy molecules in a 1:1 ratio, which have stacking interaction with each other in the solution. 3 crystallizes in the orthorhombic space group Ibam, with a = 11.1283(5) Å, b = 15.5927(8) Å, c = 22.3178(11) Å, Z = 4. 3 is made up of two-dimensional square [Cu(4)(4,4'-bpy)(4)] grids, where the square cavity has dimensions of 11.13 x 11.16 Å. Each [4,4'-H(2)bpy](2+) cation is clathrated in a square cavity and stacks with one pair of opposite edges of the host square cavity in an offset fashion with the face-to-face distance of ca. 3.95 Å. Within each cavity, the [4,4'-H(2)bpy](2+) cation forms twin three-center hydrogen bonds with two pairs of ClO(4)(-) anions. The results suggest that the guest 2,4'-bpy molecules and protonated [4,4'-H(2)bpy](2+) cations present in the reaction systems serve as structure-directing templates in the formation of the crystal structures and exclude self-inclusion of the networks having larger square cavities.

Matched MeSH terms: Salts
Fulltext Potassium aluminium sulphate (Alum) inhibits growth of human axillary malodor-producing skin flora in vitro

Hassanain Al-Talib, Nur Izzati Syamimi Mohd Nasir, Hafizuddin Yaziz, Nur Fatihah Zulkafli, Nur Aqidah Adani, Ahmad Ikhwan Noor Rashidi, et al.

Journal of Clinical and Health Sciences, 2016;1:59-63.

Axillary malodor is caused by microbial biotransformation of non-smelling molecules present in apocrine secretions, into volatile odorous molecules. This study aimed to determine the antimicrobial activities of potassium aluminium salts (alum) against four malodor-producing axillary bacterial flora, as an alternative natural product for reducing axillary malodor.

Matched MeSH terms: Salts
Temperature dependency of aqueous biphasic systems: an alternative approach for exploring the differences between Coulombic-dominated salts and ionic liquids

E Silva FA, Pereira JFB, Kurnia KA, Ventura SPM, Silva AMS, Rogers RD, et al.

Chem Commun (Camb), 2017 Apr 27.
PMID: 28447082 DOI: 10.1039/c7cc02294h

Herein we propose an alternative way to distinguish ionic liquids from Coulombic-dominated salts, based not on their upper limit melting temperature (100 °C), but on the trend of their phase-forming abilities to create aqueous biphasic systems as a function of temperature, in which a wider plethora of interactions can be appraised.

Matched MeSH terms: Salts
Synthesis and characterization of mixed ligand complexes of caffeine, adenine and thiocyanate with some transition metal ions

Shaker SA, Yang Farina, Mahmmod S, Eskender M

Sains Malaysiana, 2010;39.

An ethanolic solution of caffeine was added to an aqueous solution of metal salts and followed by adding ethanolic solution of adenine and an aqueous solution of potassium thiocyanate to give complexes with general formula [M(CA)2(Ad)X2] where CA is caffeine, Ad is adenine, X is thiocyanate ion and M is Co(II), Ni(II), Cu(II), Zn(II) and Cd(II). The resulting products were characterized using UV-visible and infrared spectroscopies. Elemental analyses were performed using C, H, N analysis and atomic absorption techniques. The magnetic susceptibility and the conductivity were also measured. The results suggested that the complexes have octahedral geometry.

Matched MeSH terms: Salts
Possible role of inter-domain salt bridges in oligopeptidase B from Trypanosoma brucei: critical role of Glu172 of non-catalytic β-propeller domain in catalytic activity and Glu490 of catalytic domain in stability of OPB

Fukumoto J, Ismail NI, Kubo M, Kinoshita K, Inoue M, Yuasa K, et al.

J. Biochem., 2013 Nov;154(5):465-73.
PMID: 23946505 DOI: 10.1093/jb/mvt077

Oligopeptidase B (OPB) is a member of the prolyl oligopeptidase (POP) family of serine proteases. OPB in trypanosomes is an important virulence factor and potential pharmaceutical target. Characteristic structural features of POP family members include lack of a propeptide and presence of a β-propeller domain (PD), although the role of the β-PD has yet to be fully understood. In this work, residues Glu(172), Glu(490), Glu(524) and Arg(689) in Trypanosoma brucei OPB (Tb OPB), which are predicted to form inter-domain salt bridges, were substituted for Gln and Ala, respectively. These mutants were evaluated in terms of catalytic properties and stability. A negative effect on kcat/Km was obtained following mutation of Glu(172) or Arg(689). In contrast, the E490Q mutant exhibited markedly decreased thermal stability, although this mutation had less effect on catalytic properties compared to the E172Q and R689A mutants. Trypsin digestion showed that the boundary regions between the β-PD and catalytic domains (CDs) of the E490Q mutant are unfolded with heat treatment. These results indicated that Glu(490) in the CD plays a role in stabilization of Tb OPB, whereas Glu(172) in the β-PD is critical for the catalytic activity of Tb OPB.

Matched MeSH terms: Salts/metabolism; Salts/chemistry

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