Browse publications by year: 2010

  1. Cheng HM
    Adv Physiol Educ, 2010 Mar;34(1):20-1.
    PMID: 20237230 DOI: 10.1152/advan.00096.2009
    MeSH terms: Awards and Prizes; Competitive Behavior*; Education, Medical, Undergraduate/methods*; Educational Measurement; Group Processes; Humans; Motivation*; Physiology/education*; Schools, Medical*; Students, Medical/psychology*; Teaching/methods*; Program Development; Comprehension
  2. Khoo TL, Halim AS, Saad AZ, Dorai AA
    Burns, 2010 Sep;36(6):897-904.
    PMID: 20299154 DOI: 10.1016/j.burns.2009.03.007
    Glycerol-preserved skin allograft (GPA) plays a crucial role in the management of burns. Its indications include wound-bed preparation, definitive dressing and sandwich grafting technique.
    MeSH terms: Adolescent; Adult; Aged; Aged, 80 and over; Burns/pathology; Burns/surgery*; Child; Child, Preschool; Female; Glycerol*; Graft Survival; Humans; Infant; Length of Stay; Male; Middle Aged; Preservatives, Pharmaceutical*; Tissue Preservation/methods*; Transplantation, Autologous; Skin Transplantation/methods*; Young Adult
  3. Sakeena MH, Muthanna FA, Ghassan ZA, Kanakal MM, Elrashid SM, Munavvar AS, et al.
    J Oleo Sci, 2010;59(4):223-8.
    PMID: 20299769
    The aim of the present study is to formulate and investigate the potential of nanoemulsion formulation for topical delivery of ketoprofen. In this study, Palm Oil Esters (POEs) a newly introduced oil by Universiti Putra Malaysia researchers was chosen for the oil phase of the nanoemulsion, because the oil was reported to be a good vehicle for pharmaceutical use. Oil-in-water nanoemulsion was prepared by spontaneous emulsification method. The droplets size was studied by laser scattering spectroscopy (Nanophox) and Transmission Electron Microscopy (TEM). Franz diffusion cells were used, to determine the drug release and drug transferred through methyl acetate cellulose membrane (artificial membrane). The results of droplets size analysis shows the droplets are in the range of nanoemulsion which is below than 500 nm. The in vitro release profile shows a sufficient percentage of drugs released through the methyl acetate cellulose membrane. This initial study showed that the nanoemulsion formulated using POEs has great potential for topical delivery of ketoprofen.
    MeSH terms: Administration, Topical; Cell Membrane Permeability; Chemistry, Pharmaceutical; Emulsions; Esters*; Ketoprofen/administration & dosage*; Ketoprofen/pharmacokinetics; Membranes, Artificial; Methylcellulose; Particle Size; Plant Oils*; Water; Drug Delivery Systems*; Nanoparticles*
  4. Matsui M, Hamidy A, Murphy RW, Khonsue W, Yambun P, Shimada T, et al.
    Mol Phylogenet Evol, 2010 Jul;56(1):259-72.
    PMID: 20302957 DOI: 10.1016/j.ympev.2010.03.014
    By investigating genealogical relationships, we estimated the phylogenetic history and biogeography in the megophryid genus Leptobrachium (sensu lato, including Vibrissaphora) from southern China, Indochina, Thailand and the Sundaland. The genealogical relationships among the 30 named and unnamed taxa were estimated using 2009 bp of sequences from the mitochondrial DNA genes 12S rRNA, tRNA(val), and 16S rRNA using maximum parsimony, maximum likelihood, and Bayesian inference methods. The genus Leptobrachium was a well-supported monophyletic group that contained two major clades. One clade had three subclades primarily from disjunct regions including Borneo, Peninsular Malaysia and Java, and Thailand. The Bornean subclade included one species each from the Philippines and Sumatra. The other major clade consisted of two subclades, one from Indochina and the other from southern China (Vibrissaphora). Divergence times estimated an old evolutionary history of each subclade, one that could not be explained by the geohistory of Southeast Asian major landmasses.
    MeSH terms: Animals; Anura/classification*; Anura/genetics; Asia, Southeastern; Bayes Theorem; DNA, Mitochondrial/genetics*; Geography; Models, Genetic; Phylogeny*; Likelihood Functions; Sequence Alignment; Sequence Analysis, DNA; Evolution, Molecular*; Genes, Mitochondrial
  5. Chan CH, Tiwari A, Fong DY, Ho PC
    Int J Nurs Stud, 2010 Jul;47(7):918-25.
    PMID: 20303490 DOI: 10.1016/j.ijnurstu.2010.01.003
    BACKGROUND: Post-traumatic stress disorder is one of the most prevalent mental health sequelae of intimate partner violence, and as a result, it has been extensively documented in Western literature. However, whether abused women from non-Western cultures experience similar post-traumatic responses to intimate partner violence is less documented.

    OBJECTIVES: The objectives of this paper were (1) to review the literature for information about post-traumatic stress disorder among Chinese women survivors of intimate partner violence; (2) to provide a synthesis of the literature on post-traumatic stress disorder among abused Chinese women; and (3) to identify implications for practice and to suggest directions for research relating to post-traumatic stress disorder among abused Chinese women.

    DESIGN: A systematic review of the literature.

    DATA SOURCES: Following a systematic search for relevant literature in computerized databases and manual searches of English and Chinese language publications, five papers reporting on four studies conducted in China, Taiwan, Malaysia, and the United States were included in the review.

    REVIEW METHODS: Abstracts meeting the inclusion criteria were reviewed independently by two of the authors and any discrepancies were resolved by discussion. Full papers for selected abstracts were then retrieved and assessed independently by the same reviewers.

    RESULTS: The present literature review revealed a paucity of information relating to post-traumatic stress disorder symptoms or diagnoses in abused Chinese women. Nevertheless, a link between post-traumatic stress disorder and intimate partner violence was demonstrated by the reviewed papers.

    CONCLUSIONS: Caution should be exercised when making comparison of the findings across the four studies because of the inherent methodological differences. Also, as the assessment tools have not been validated for culture-bound interpretation of trauma and symptom manifestation, comparisons of findings for Chinese women to women in Western literature should be undertaken with due consideration. Implications for practice and recommendations for future research are discussed.

    MeSH terms: China; Female; Humans; Sexual Partners*; Stress Disorders, Post-Traumatic/epidemiology*; Domestic Violence*; Survivors*
  6. Wibowo TC, Saad N
    ISA Trans, 2010 Jul;49(3):335-47.
    PMID: 20304404 DOI: 10.1016/j.isatra.2010.02.005
    This paper discusses the empirical modeling using system identification technique with a focus on an interacting series process. The study is carried out experimentally using a gaseous pilot plant as the process, in which the dynamic of such a plant exhibits the typical dynamic of an interacting series process. Three practical approaches are investigated and their performances are evaluated. The models developed are also examined in real-time implementation of a linear model predictive control. The selected model is able to reproduce the main dynamic characteristics of the plant in open-loop and produces zero steady-state errors in closed-loop control system. Several issues concerning the identification process and the construction of a MIMO state space model for a series interacting process are deliberated.
    MeSH terms: Algorithms; Computer Systems; Forecasting; Gases; Industry/methods*; Pilot Projects; Reproducibility of Results; Models, Statistical*; Linear Models
  7. Kamil RN, Yusup S
    Bioresour Technol, 2010 Aug;101(15):5877-84.
    PMID: 20304636 DOI: 10.1016/j.biortech.2010.02.084
    A mathematical model describing chemical kinetics of transesterification of palm-based methyl esters with trimethylolpropane has been developed. The model was developed by utilizing nonlinear regression method, which is an efficient and powerful way to determine rate constants for both forward and reverse reactions. A comparison with previous study which excludes the reverse reactions was made. The model was based on the reverse mechanism of transesterification reactions and describes concentration changes of trimethylolpropane, monoesters and diesters production. The developed model was validated against data from the literature. The reaction rate constants were determined using MATLAB version 7.2 and the ratios of rate constants obtained were well in agreement with those reported in the literature. A good correlation between model simulations and experimental data was observed. It was proven that both methods were able to predict the rate constants with plausible accuracy.
    MeSH terms: Computer Simulation; Esterification; Esters/chemistry*; Kinetics; Models, Chemical*; Propylene Glycols/chemistry*; Arecaceae/chemistry*
  8. Wilting A, Cord A, Hearn AJ, Hesse D, Mohamed A, Traeholdt C, et al.
    PLoS One, 2010;5(3):e9612.
    PMID: 20305809 DOI: 10.1371/journal.pone.0009612
    The flat-headed cat (Prionailurus planiceps) is one of the world's least known, highly threatened felids with a distribution restricted to tropical lowland rainforests in Peninsular Thailand/Malaysia, Borneo and Sumatra. Throughout its geographic range large-scale anthropogenic transformation processes, including the pollution of fresh-water river systems and landscape fragmentation, raise concerns regarding its conservation status. Despite an increasing number of camera-trapping field surveys for carnivores in South-East Asia during the past two decades, few of these studies recorded the flat-headed cat.
    MeSH terms: Animals; Asia, Southeastern; Cats/physiology*; Conservation of Natural Resources; Geography; Humans; Models, Biological; Population Density*; Models, Statistical; Computational Biology/methods; Extinction, Biological; Endangered Species*
  9. Lord AT, Mohandas K, Somanath S, Ambu S
    PMID: 20307325 DOI: 10.1186/1476-0711-9-11
    The aim of this study was to investigate the presence of multidrug resistant yeasts in the faeces of synanthropic wild birds from the Bangsar suburb of Kuala Lumpur.
    MeSH terms: Animals; Antifungal Agents/pharmacology*; Birds/microbiology*; Environmental Monitoring; Face/microbiology; Humans; Malaysia; Mycoses/microbiology; Mycoses/transmission; Yeasts/classification; Yeasts/drug effects*; Yeasts/isolation & purification; Drug Resistance, Multiple, Fungal*
  10. Hussain AI, Cordeiro M, Sevilla E, Liu J
    Vaccine, 2010 May 14;28(22):3848-55.
    PMID: 20307595 DOI: 10.1016/j.vaccine.2010.03.005
    Currently MedImmune manufactures cold-adapted (ca) live, attenuated influenza vaccine (LAIV) from specific-pathogen free (SPF) chicken eggs. Difficulties in production scale-up and potential exposure of chicken flocks to avian influenza viruses especially in the event of a pandemic influenza outbreak have prompted evaluation and development of alternative non-egg based influenza vaccine manufacturing technologies. As part of MedImmune's effort to develop the live attenuated influenza vaccine (LAIV) using cell culture production technologies we have investigated the use of high yielding, cloned MDCK cells as a substrate for vaccine production by assessing host range and virus replication of influenza virus produced from both SPF egg and MDCK cell production technologies. In addition to cloned MDCK cells the indicator cell lines used to evaluate the impact of producing LAIV in cells on host range and replication included two human cell lines: human lung carcinoma (A549) cells and human muco-epidermoid bronchiolar carcinoma (NCI H292) cells. The influenza viruses used to infect the indicators cell lines represented both the egg and cell culture manufacturing processes and included virus strains that composed the 2006-2007 influenza seasonal trivalent vaccine (A/New Caledonia/20/99 (H1N1), A/Wisconsin/67/05 (H3N2) and B/Malaysia/2506/04). Results from this study demonstrate remarkable similarity between influenza viruses representing the current commercial egg produced and developmental MDCK cell produced vaccine production platforms. MedImmune's high yielding cloned MDCK cells used for the cell culture based vaccine production were highly permissive to both egg and cell produced ca attenuated influenza viruses. Both the A549 and NCI H292 cells regardless of production system were less permissive to influenza A and B viruses than the MDCK cells. Irrespective of the indicator cell line used the replication properties were similar between egg and the cell produced influenza viruses. Based on these study results we conclude that the MDCK cell produced and egg produced vaccine strains are highly comparable.
    MeSH terms: Animals; Chickens; Dogs; Eggs/virology; Hemagglutination Inhibition Tests; Humans; Influenza Vaccines/biosynthesis*; Influenza Vaccines/immunology; RNA, Viral/analysis; Vaccines, Attenuated/biosynthesis; Vaccines, Attenuated/immunology; Virus Replication*; Cell Line, Tumor; Influenza A Virus, H1N1 Subtype/growth & development*; Influenza A Virus, H1N1 Subtype/immunology; Influenza A Virus, H1N1 Subtype/physiology; Influenza A Virus, H3N2 Subtype/growth & development*; Influenza A Virus, H3N2 Subtype/immunology; Influenza A Virus, H3N2 Subtype/physiology
  11. Chacko JP, Joseph C
    J Oral Maxillofac Surg, 2010 Apr;68(4):943-4.
    PMID: 20307780 DOI: 10.1016/j.joms.2009.04.009
    MeSH terms: Exostoses/surgery*; Humans; Surgical Flaps*; Stents; Oral Surgical Procedures/methods*; Reconstructive Surgical Procedures/methods; Palate, Hard/surgery*
  12. Maizura H, Retneswari M, Moe H, Hoe VC, Bulgiba A
    Occup Med (Lond), 2010 May;60(3):219-24.
    PMID: 20308258 DOI: 10.1093/occmed/kqq001
    Information on job strain exposure among Malaysian workers in multinational companies is limited.
    MeSH terms: Adult; Child; Employment/organization & administration; Employment/psychology*; Epidemiologic Methods; Female; Humans; Job Satisfaction; Malaysia/epidemiology; Male; Occupational Diseases/epidemiology*; Personnel Management*; Professional Competence; Socioeconomic Factors; Stress, Psychological/epidemiology*; Organizational Culture; Internationality
  13. Ratnalingam V, Eu AL, Ng GL, Taharin R, John E
    Cornea, 2010 May;29(5):485-9.
    PMID: 20308876 DOI: 10.1097/ICO.0b013e3181c29696
    To evaluate the recurrence rate, surgical time, and postoperative pain between conjunctival autografting with sutures and with fibrin adhesive in pterygium surgery.
    MeSH terms: Adult; Aged; Aged, 80 and over; Conjunctiva/transplantation*; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Postoperative Complications; Prospective Studies; Pterygium/ethnology; Pterygium/pathology; Pterygium/surgery*; Suture Techniques*; Time Factors; Tissue Adhesives/therapeutic use*; Transplantation, Autologous; Fibrin Tissue Adhesive/therapeutic use*; Secondary Prevention
  14. Alzoubi AS, Kandaiya S, Shukri A, Elsherbieny E
    Australas Phys Eng Sci Med, 2010 Jun;33(2):137-44.
    PMID: 20309667 DOI: 10.1007/s13246-010-0011-y
    Second cancer induction in the contralateral breast (CB) is an issue of some concern in breast radiotherapy especially for women under the age of 45 years at the time of treatment. The CB dose from 2-field and 3-field techniques in post-mastectomy chest wall irradiations in an anthropomorphic phantom as well as in patients were measured using thermoluminescent dosimeters (TLDs) at the local radiotherapy center. Breast and chest wall radiotherapy treatments were planned conformally (3D-CRT) and delivered using 6-MV photons. The measured CB dose at the surface fell sharply with distance from the field edge. However, the average ratio of the measured to the calculated CB dose using the pencil beam algorithm at the surface was approximately 53%. The mean and median measured internal dose at the posterior border of CB in a phantom was 5.47+/-0.22 cGy and 5.44 cGy, respectively. The internal CB dose was relatively independent of depth. In the present study the internal CB dose is 2.1-4.1% of the prescribed dose which is comparable to the values reported by other authors.
    MeSH terms: Adult; Aged; Breast Neoplasms/radiotherapy*; Female; Humans; Malaysia; Middle Aged; Neoplasms, Radiation-Induced/etiology; Radiotherapy Dosage; Risk Factors; Thermoluminescent Dosimetry; Neoplasms, Second Primary/etiology; Phantoms, Imaging; Radiotherapy, Conformal/adverse effects; Thoracic Wall/radiation effects
  15. Ismail M, Al-Naqeeb G, Mamat WA, Ahmad Z
    Nutr Metab (Lond), 2010;7:23.
    PMID: 20331906 DOI: 10.1186/1743-7075-7-23
    Gamma-oryzanol (OR), a phytosteryl ferulate mixture extracted from rice bran oil, has a wide spectrum of biological activities in particular, it has antioxidant properties.
  16. Lee ES, Kim LH, Abdullah WA, Peh SC
    Pathobiology, 2010;77(2):96-105.
    PMID: 20332669 DOI: 10.1159/000278291
    This study aimed to examine (1) the expression of P16 protein relative to sites of presentation, immunophenotypic subgroups and proliferative indices of tumour cells, and (2) the relationship between p16 gene alterations and P16 protein overexpression in 70 cases of diffuse large B cell lymphoma (DLBCL).
    MeSH terms: Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Gene Expression Regulation, Neoplastic*; Lymphoma, Large B-Cell, Diffuse/genetics; Lymphoma, Large B-Cell, Diffuse/metabolism*; Lymphoma, Large B-Cell, Diffuse/pathology; In Situ Hybridization, Fluorescence; Cyclin-Dependent Kinase Inhibitor p16/genetics; Cyclin-Dependent Kinase Inhibitor p16/metabolism*; Genes, p16*; Cell Proliferation
  17. Zyoud SH, Awang R, Sulaiman SA, Al-Jabi SW
    Pharmacoepidemiol Drug Saf, 2010 May;19(5):511-7.
    PMID: 20333776 DOI: 10.1002/pds.1940
    Acetaminophen poisoning is a common clinical problem, and early identification of patients with more severe poisoning is key to improving outcomes.
    MeSH terms: Acetaminophen/poisoning*; Adult; Bilirubin/blood; Creatinine/blood; Diarrhea/chemically induced; Diarrhea/diagnosis; Diarrhea/epidemiology*; Female; Humans; Length of Stay; Malaysia/epidemiology; Male; Nausea/chemically induced; Nausea/diagnosis; Nausea/epidemiology*; Potassium/blood; Prognosis; Prothrombin Time; Retrospective Studies; Vomiting/chemically induced; Vomiting/diagnosis; Vomiting/epidemiology*; Cohort Studies; Prevalence; Logistic Models; Pharmacoepidemiology; Statistics, Nonparametric; Analgesics, Non-Narcotic/poisoning*; Young Adult; Drug-Induced Liver Injury/diagnosis; Drug-Induced Liver Injury/epidemiology; Drug-Induced Liver Injury/prevention & control
  18. Zamri-Saad M, Amal MN, Siti-Zahrah A
    J Comp Pathol, 2010 Aug-Oct;143(2-3):227-9.
    PMID: 20334871 DOI: 10.1016/j.jcpa.2010.01.020
    The pathological changes present in 300 red tilapias (Oreochromis spp.) naturally infected by Streptococcus agalactiae are described. The most consistent gross findings were marked congestion of internal organs, particularly the liver, spleen and kidneys. Other features included exophthalmos, softening of the brain and the occasional accumulation of fluid within the abdominal cavity. Microscopical examination confirmed the presence of marked congestion of the liver, spleen and kidneys. The endothelial cells lining major blood vessels of the liver and occasionally the spleen were swollen and vacuolated. There was evidence of vascular thrombosis with infarction of surrounding tissue. Bacterial colonies were noted within and immediately surrounding the affected blood vessels. The meninges were thickened by the infiltration of numerous heterophils. Similar infiltrates of heterophils and lymphocytes were observed in the lamina propria of the intestine. The kidneys were severely congested and haemorrhagic, with extensive interstitial nephritis.
    MeSH terms: Animals; Disease Outbreaks; Fish Diseases/epidemiology; Fish Diseases/pathology*; Fisheries; Kidney/pathology; Liver/pathology; Malaysia/epidemiology; Meninges/pathology; Spleen/pathology; Streptococcal Infections/epidemiology; Streptococcal Infections/pathology; Streptococcal Infections/veterinary*; Streptococcus agalactiae*; Tilapia/microbiology*
  19. Syed-Mohamad SM, Ali SH, Mat-Husin MN
    Health Inf Manag, 2010;39(1):30-5.
    PMID: 20335647
    This paper describes the method used to develop the One Stop Crisis Centre (OSCC) Portal, an open source web-based electronic patient record system (EPR) for the One Stop Crisis Center, Hospital Universiti Sains Malaysia (HUSM) in Kelantan, Malaysia. Features and functionalities of the system are presented to demonstrate the workflow. Use of the OSCC Portal improved data integration and data communication and contributed to improvements in care management. With implementation of the OSCC portal, improved coordination between disciplines and standardisation of data in HUSM were noticed. It is expected that this will in turn result in improved data confidentiality and data integrity. The collected data will also be useful for quality assessment and research. Other low-resource centers with limited computer hardware and access to open-source software could benefit from this endeavour.
    MeSH terms: Computer Communication Networks; Hospital Information Systems; Humans; Malaysia; Software; Systems Integration; Internet*; Electronic Health Records*
  20. Kong KW, Khoo HE, Prasad KN, Ismail A, Tan CP, Rajab NF
    Molecules, 2010 Feb 23;15(2):959-87.
    PMID: 20335956 DOI: 10.3390/molecules15020959
    By-products derived from food processing are attractive source for their valuable bioactive components and color pigments. These by-products are useful for development as functional foods, nutraceuticals, food ingredients, additives, and also as cosmetic products. Lycopene is a bioactive red colored pigment naturally occurring in plants. Industrial by-products obtained from the plants are the good sources of lycopene. Interest in lycopene is increasing due to increasing evidence proving its preventive properties toward numerous diseases. In vitro, in vivo and ex vivo studies have demonstrated that lycopene-rich foods are inversely associated to diseases such as cancers, cardiovascular diseases, diabetes, and others. This paper also reviews the properties, absorption, transportation, and distribution of lycopene and its by-products in human body. The mechanism of action and interaction of lycopene with other bioactive compounds are also discussed, because these are the crucial features for beneficial role of lycopene. However, information on the effect of food processing on lycopene stability and availability was discussed for better understanding of its characteristics.
    MeSH terms: Antioxidants/metabolism; Biological Products/metabolism*; Carotenoids/blood; Carotenoids/metabolism*; Carotenoids/chemistry; Food; Humans; Pigmentation*; Pigments, Biological/metabolism*
External Links