Browse publications by year: 2013

  1. Loy SL, Jan Mohamed HJ
    Int J Food Sci Nutr, 2013 Sep;64(6):668-73.
    PMID: 23594439 DOI: 10.3109/09637486.2013.787398
    This study aimed to assess the relative validity of maternal dietary patterns derived from a semi-quantitative food frequency questionnaire (FFQ). A total of 162 pregnant women aged 19-40-years-old were enrolled from the Universiti Sains Malaysia (USM) Birth Cohort Study in year 2010 and 2011. The FFQ was compared with three 24-h dietary recalls (DRs). Two major dietary patterns were derived from the principle component analysis which are labeled as Healthy and Less-Healthy patterns. The Pearson correlation coefficients between FFQ and DRs for Healthy and Less-Healthy patterns were 0.59 and 0.63, respectively. At least 45% of the participants were correctly classified into the same third from the FFQ and DR for both dietary patterns. The weighted kappa showed moderate agreement for Healthy pattern while good agreement for Less-Healthy pattern between these two dietary assessment methods. Our results indicate reasonable validity of the dietary patterns identified from the FFQ in pregnant women.
    MeSH terms: Adult; Female; Health Promotion; Humans; Malaysia; Patient Compliance/ethnology; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Prospective Studies; Surveys and Questionnaires; Reproducibility of Results; Cohort Studies; Nutrition Assessment*; Nutrition Policy; Principal Component Analysis; Young Adult
  2. Azmin S, Sahathevan R, Suehazlyn Z, Law ZK, Rabani R, Nafisah WY, et al.
    BMC Infect Dis, 2013;13:179.
    PMID: 23594500 DOI: 10.1186/1471-2334-13-179
    BACKGROUND: Dengue is a common illness in the tropics. Equally common are neurological complications that stem from dengue infection. However, to date, parkinsonism following dengue has not been reported in medical literature.
    CASE PRESENTATION: A previously well 18-year old man developed parkinsonism, in addition to other neurological symptoms following serologically confirmed dengue fever. Alternative etiologies were excluded by way of imaging and blood investigations.
    CONCLUSIONS: The authors detail the first reported case of parkinsonism complicating dengue fever. Keeping rare presentations of common illnesses in mind, it behoves clinicians to consider parkinsonism as a complication following dengue infection. This would prevent injudicious treatment with L-dopa and dopamine agonists. Immunosuppression with steroids has been shown to be helpful in certain cases.
    MeSH terms: Adolescent; Brain/radiography; Dengue/complications*; Humans; Magnetic Resonance Imaging; Male; Parkinsonian Disorders/diagnosis*; Parkinsonian Disorders/pathology*
  3. Sidik NA, Khakbaz M, Jahanshaloo L, Samion S, Darus AN
    Nanoscale Res Lett, 2013;8(1):178.
    PMID: 23594696 DOI: 10.1186/1556-276X-8-178
    This paper presents a numerical study of the thermal performance of fins mounted on the bottom wall of a horizontal channel and cooled with either pure water or an Al2O3-water nanofluid. The bottom wall of the channel is heated at a constant temperature and cooled by mixed convection of laminar flow at a relatively low temperature. The results of the numerical simulation indicate that the heat transfer rate of fins is significantly affected by the Reynolds number (Re) and the thermal conductivity of the fins. The influence of the solid volume fraction on the increase of heat transfer is more noticeable at higher values of the Re.
    MeSH terms: Aluminum Oxide; Cold Temperature; Emollients; Hot Temperature; Temperature; Thermal Conductivity; Water; Convection; Phase Transition
  4. Titah HS, Abdullah SR, Mushrifah I, Anuar N, Basri H, Mukhlisin M
    Bull Environ Contam Toxicol, 2013 Jun;90(6):714-9.
    PMID: 23595348 DOI: 10.1007/s00128-013-0996-5
    Wilting, especially of the leaves, was observed as an initial symptom of arsenate [As(V)] to Ludwigia octovalvis (Jacq.) P. H. Raven. The plants tolerated As(V) levels of 39 mg kg⁻¹ for as long as 35 days of exposure. After 91 days, the maximum concentration of As uptake in the plant occurred at As(V) concentration of 65 mg kg⁻¹ while As concentration in the stems, roots and leaves were 6139.9 ± 829.5, 1284.5 ± 242.9 and 1126.1 ± 117.2 mg kg⁻¹, respectively. In conclusion, As(V) could cause toxic effects in L. octovalvis and the plants could uptake and accumulate As in plant tissues.
    MeSH terms: Arsenic/toxicity*; Microscopy, Electron, Scanning; Silicon Dioxide*; Soil Pollutants/toxicity*; Biomass; Onagraceae/drug effects*
  5. Siew WH, Tan KL, Babaei MA, Cheah PS, Ling KH
    PMID: 23596395 DOI: 10.3389/fncel.2013.00041
    Intellectual disability (ID) is one of the many features manifested in various genetic syndromes leading to deficits in cognitive function among affected individuals. ID is a feature affected by polygenes and multiple environmental factors. It leads to a broad spectrum of affected clinical and behavioral characteristics among patients. Until now, the causative mechanism of ID is unknown and the progression of the condition is poorly understood. Advancement in technology and research had identified various genetic abnormalities and defects as the potential cause of ID. However, the link between these abnormalities with ID is remained inconclusive and the roles of many newly discovered genetic components such as non-coding RNAs have not been thoroughly investigated. In this review, we aim to consolidate and assimilate the latest development and findings on a class of small non-coding RNAs known as microRNAs (miRNAs) involvement in ID development and progression with special focus on Down syndrome (DS) and X-linked ID (XLID) [including Fragile X syndrome (FXS)].
  6. Ting A, Chow Y, Tan W
    J Tradit Chin Med, 2013 Feb;33(1):119-24.
    PMID: 23596824
    The increasing popularity and widespread use of traditional Chinese herbs as alternative medicine have sparked an interest in understanding their biosafety, especially in decoctions that are consumed. This study aimed to assess the level of microbial and heavy metal contamination in commonly consumed herbal medicine in Malaysia and the effects of boiling on these contamination levels.
    MeSH terms: Bacteria/classification; Bacteria/growth & development; Bacteria/isolation & purification*; Drug Contamination*; Drugs, Chinese Herbal/analysis*; Plants, Medicinal/microbiology*; Plants, Medicinal/chemistry*; Metals, Heavy/analysis*
  7. Lau BF, Abdullah N, Aminudin N
    J Agric Food Chem, 2013 May 22;61(20):4890-7.
    PMID: 23597270 DOI: 10.1021/jf4002507
    The chemical composition of the tiger's milk mushroom (Lignosus rhinocerotis) from different developmental stages, i.e., the fruit body, sclerotium, and mycelium, was investigated for the first time. The fruit body and sclerotium of L. rhinocerotis were rich in carbohydrates and dietary fibers but low in fat. Protein levels in L. rhinocerotis were moderate, and all essential amino acids, except tryptophan, were present. The mycelium contained high levels of potassium, phosphorus, magnesium, riboflavin, and niacin and appreciable amounts of essential fatty acids. The results indicated that the sclerotium of L. rhinocerotis that was used in ethnomedicine was not superior to the fruit body and mycelium with regard to the nutritional content and bioactive constituents. Our findings provide some insights into the selection of appropriate mushroom part(s) of L. rhinocerotis and proper cultivation techniques for the development of new nutraceuticals or dietary supplements.
    MeSH terms: Dietary Carbohydrates/analysis; Dietary Fats/analysis; Dietary Fiber/analysis; Fatty Acids, Essential/analysis; Fermentation; Minerals/analysis; Nutritive Value*; Polyporaceae/growth & development*; Polyporaceae/chemistry*; Vitamins/analysis; Dietary Supplements/analysis; Mycelium/chemistry; Fruiting Bodies, Fungal/chemistry
  8. Loh SH, Sanagi MM, Wan Ibrahim WA, Hasan MN
    Talanta, 2013 Mar 15;106:200-5.
    PMID: 23598117 DOI: 10.1016/j.talanta.2012.12.032
    A new microextraction procedure termed multi-walled carbon nanotube-impregnated agarose film microextraction (MWCNT-AFME) has been developed. The method utilized multi-walled carbon nanotubes (MWCNTs) immobilized in agarose film to serve as adsorbent in solid phase microextraction (SPME). The film was prepared by mixing the MWCNTs in agarose solution and drying the mixture in oven. Extraction of selected polycyclic aromatic hydrocarbons was performed by inserting a needle through circular MWCNT-impregnated agarose films (5 mm diameter) and the assembly was dipped into an agitated sample solution prior to micro high performance liquid chromatography-ultraviolet analysis. Back extraction was then performed using ultrasonication of the films in 100 μL of solvent. The film was discarded after single use, thus avoiding any analyte carry-over effect. Due to the mesoporous nature of the agarose film, the MWCNTs were immobilized easily within the film and thus allowing for close contact between adsorbent and analytes. Under the optimized extraction conditions, the technique achieved trace LODs in the range of 0.1 to 50 ng L(-1) for the targeted analytes, namely fluoranthene, phenanthrene and benzo[a]pyrene. The method was successfully applied to the analysis of spiked green tea beverage samples with good relative recoveries in the range of 91.1 to 107.2%. The results supported the feasibility of agarose to serve as adsorbent holder in SPME which then minimizes the consumption of chemicals and disposal cost of organic wastes.
    MeSH terms: Adsorption; Benzopyrenes/isolation & purification*; Beverages/analysis*; Chromatography, High Pressure Liquid; Environmental Pollutants/isolation & purification*; Fluorenes/isolation & purification*; Phenanthrenes/isolation & purification*; Sepharose/chemistry*; Sonication; Nanotubes, Carbon; Solid Phase Microextraction/methods
  9. Norizan SN, Yin WF, Chan KG
    Sensors (Basel), 2013;13(4):5117-29.
    PMID: 23598500 DOI: 10.3390/s130405117
    Quorum sensing enables bacteria to control the gene expression in response to the cell density. It regulates a variety of bacterial physiological functions such as biofilm formation, bioluminescence, virulence factors and swarming which has been shown contribute to bacterial pathogenesis. The use of quorum sensing inhibitor would be of particular interest in treating bacterial pathogenicity and infections. In this work, we have tested caffeine as quorum sensing inhibitor by using Chromobacterium violaceum CV026 as a biosensor. We verified that caffeine did not degrade the N-acyl homoserine lactones tested. In this work, it is shown that caffeine could inhibit N-acyl homoserine lactone production and swarming of a human opportunistic pathogen, namely Pseudomonas aeruginosa PA01. To the best of our knowledge, this is the first documentation providing evidence on the presence of anti-quorum sensing activity in caffeine. Our work will allow caffeine to be explored as anti-infective drugs.
    MeSH terms: Anti-Bacterial Agents/pharmacology; Biological Assay; Caffeine/pharmacology*; Chromobacterium/drug effects; Humans; Microbial Sensitivity Tests; Movement/drug effects; Pseudomonas aeruginosa/drug effects*; Quorum Sensing/drug effects*; Acyl-Butyrolactones/metabolism
  10. Singh HJ, Saleh HI, Gupalo S, Omar E
    Sheng Li Xue Bao, 2013 Apr 25;65(2):149-57.
    PMID: 23598870
    Although melatonin supplementation is known to influence numerous physiological functions, little is however known of its effects on pregnancy outcome. This study investigated the effects of melatonin supplementation on pregnancy outcome in Wistar-Kyoto (WKY) and Sprague-Dawley (SD) rats aged 12-13 weeks. Upon confirmation of proestrus, each female rat was housed overnight with a male of the same strain. On the next morning, following confirmation of mating (vaginal smear), WKY female rats were isolated into individual metabolic cages and given 0, 25, 50 or 100 mg/kg per day of melatonin in drinking water from day 1 of pregnancy to day 21 postpartum. SD females were given 0 or 100 mg/kg per day of melatonin. Maternal weight, duration of pregnancy, litter size, birth weight and body weight of pups up to day 42, and pup mortality were recorded. Data were analyzed using ANOVA for repeated measures. Compared to controls, maternal weight gain during pregnancy was significantly lower in melatonin-supplemented dams (P < 0.01). Litter size was significantly smaller in melatonin-supplemented dams (P < 0.01). Mean birth weight of pups was significantly lower only in pups of dams given 100 mg/kg per day of melatonin (P < 0.001). Mean body weight of pups of dams given melatonin was significantly lower than controls (P < 0.01). Pup mortalities were 9.5% and 21.6% in WKY dams given 25 and 100 mg/kg per day of melatonin respectively, and all pup deaths occurred after day 21 of weaning. The results suggest that melatonin supplementation during antenatal and postpartum period appears to adversely affect litter size, pup growth and mortality in WKY and SD rats. The precise mechanism causing the death is not clear.
    MeSH terms: Animals; Body Weight; Female; Litter Size; Melatonin/pharmacology*; Pregnancy; Pregnancy Outcome*; Pregnancy, Animal/drug effects*; Rats, Inbred WKY; Weaning; Rats, Sprague-Dawley; Rats
  11. Wong KW
    J Vasc Access, 2013 Jul-Sep;14(3):306.
    PMID: 23599132 DOI: 10.5301/jva.5000139
    MeSH terms: Adult; Anti-Bacterial Agents/therapeutic use; Catheterization, Central Venous/adverse effects*; Catheterization, Central Venous/instrumentation*; Catheters, Indwelling/adverse effects*; Enterobacteriaceae Infections/diagnosis; Enterobacteriaceae Infections/drug therapy; Enterobacteriaceae Infections/microbiology*; Female; Renal Dialysis*; Humans; Kidney Failure, Chronic/therapy*; Male; Middle Aged; Treatment Outcome; Pantoea/isolation & purification*; Catheter-Related Infections/diagnosis; Catheter-Related Infections/drug therapy; Catheter-Related Infections/microbiology*; Central Venous Catheters/adverse effects*
  12. Tumin M, Noh A, Chong CS, Lim SK, Abdullah N, Ng KP
    Clin Transplant, 2013 May-Jun;27(3):E316-9.
    PMID: 23600843 DOI: 10.1111/ctr.12132
    Malaysians indicating that they did not intend to become organ donors upon their death were surveyed regarding interest in non-fungible financial incentives to be granted to surviving family members. Among the 730 (56% of the total sample of 1311) indicating unwillingness to be donors, 29.6% (216/730) subsequently indicated that they would be willing donors if the government introduced policies that, upon their death, "rewarded your (their) family with incentives for your (their) deeds." Among the 69% (504/730) who insisted that they would not become organ donor even with incentive, nearly 80% (404/501) of them were able to identify relevant incentives they thought should be provided by the state to those who make organ donations upon death. The majority of both groups preferred the state provide medical benefits to a surviving family member, suggesting this may be an attractive policy option for the state to raise the deceased organ donation pool.
    MeSH terms: Adult; Attitude*; Family; Female; Humans; Male; Middle Aged; Motivation*; Tissue and Organ Procurement/economics*; Surveys and Questionnaires; Reward; Tissue Donors/psychology*
  13. Premsenthil M, Manju R, Thanaraj A, Rahman SA, Kah TA
    BMC Ophthalmol, 2013 Apr 19;13:16.
    PMID: 23601160 DOI: 10.1186/1471-2415-13-16
    BACKGROUND: To screen for visual impairment in Malaysian preschool children.

    METHODS: Visual screening was conducted in 400 preschool children aged 4 to 6 years. The screening involved two basic procedures; the distant visual acuity test using the Sheridan Gardiner chart and the depth perception test using the Langs stereoacuity test. Criteria for referral were a visual acuity of 6/12 or less in the better eye or a fail in the depth perception test.

    RESULTS: The prevalence of visual impairment was 5% (95% confidence interval [CI] = 3.3, 7.6). Of the 400 preschool children screened, 20 of them failed the distant visual acuity test or the stereopsis test. Refractive errors were the most common cause of visual impairment (95%, 95% CI = 76.2, 98.8); myopic astigmatism was the commonest type of refractive error (63.2%, 95% CI = 40.8, 80.9).

    CONCLUSION: The study is a small but important step in the effort to understand the problem of visual impairment among our preschool children. Our study showed that it is feasible to measure distant visual acuity and stereopsis in this age group.

    MeSH terms: Child; Child, Preschool; Cross-Sectional Studies; Depth Perception/physiology; Feasibility Studies; Female; Humans; Malaysia/epidemiology; Male; Refractive Errors/epidemiology; Vision Disorders/diagnosis*; Vision Disorders/epidemiology; Vision Disorders/physiopathology; Visual Acuity/physiology; Vision Screening/methods*
  14. Siar CH, Abbas SA
    PMID: 23601220 DOI: 10.1016/j.oooo.2013.02.013
    The aim of this study was to evaluate the expression and localization of tight junction proteins (TJPs) or claudins in the keratocystic odontogenic tumor (KCOT) and to correlate with its biological behavior.
    MeSH terms: Adolescent; Adult; Aged; Cell Nucleus/pathology; Child; Cytoplasm/pathology; Cytoplasmic Granules/ultrastructure; Dentigerous Cyst/pathology*; Epithelial Cells/pathology; Epithelium/pathology; Female; Humans; Immunohistochemistry; Male; Middle Aged; Odontogenic Tumors/pathology*; Radicular Cyst/pathology*; Down-Regulation; Gene Expression; Cell Polarity; Young Adult; Claudins/analysis*; Claudin-1/analysis; Claudin-3/analysis; Claudin-4/analysis; Claudin-5/analysis; Tight Junction Proteins/analysis*
  15. Ramimoghadam D, Hussein MZ, Taufiq-Yap YH
    Chem Cent J, 2013 Apr 20;7(1):71.
    PMID: 23601826 DOI: 10.1186/1752-153X-7-71
    BACKGROUND: A green approach to synthesize nanomaterials using biotemplates has been subjected to intense research due to several advantages. Palm olein as a biotemplate offers the benefits of eco-friendliness, low-cost and scale-up for large scale production. Therefore, the effect of palm olein on morphology and surface properties of ZnO nanostructures were investigated.

    RESULTS: The results indicate that palm olein as a biotemplate can be used to modify the shape and size of ZnO particles synthesized by hydrothermal method. Different morphology including flake-, flower- and three dimensional star-like structures were obtained. FTIR study indicated the reaction between carboxyl group of palm olein and zinc species had taken place. Specific surface area enhanced while no considerable change were observed in optical properties.

    CONCLUSION: Phase-pure ZnO particles were successfully synthesized using palm olein as soft biotemplating agent by hydrothermal method. The physico-chemical properties of the resulting ZnO particles can be tuned using the ratio of palm olein to Zn cation.

  16. Saifullah B, Hussein MZ, Hussein-Al-Ali SH, Arulselvan P, Fakurazi S
    Chem Cent J, 2013;7(1):72.
    PMID: 23601852 DOI: 10.1186/1752-153X-7-72
    Tuberculosis (TB), is caused by the bacteria, Mycobacterium tuberculosis and its a threat to humans since centuries. Depending on the type of TB, its treatment can last for 6-24 months which is a major cause for patients non-compliance and treatment failure. Many adverse effects are associated with the currently available TB medicines, and there has been no new anti-tuberculosis drug on the market for more than 50 year, as the drug development is very lengthy and budget consuming process.Development of the biocompatible nano drug delivery systems with the ability to minimize the side effects of the drugs, protection of the drug from enzymatic degradation. And most importantly the drug delivery systems which can deliver the drug at target site would increase the therapeutic efficacy. Nanovehicles with their tendency to release the drug in a sustained manner would result in the bioavalibilty of the drugs in the body for a longer period of time and this would reduce the dosing frequency in drug administration. The biocompatible nanovehicles with the properties like sustained release of drug of the target site, protection of the drug from physio-chemical degradation, reduction in dosing frequency, and prolong bioavailability of drug in the body would result in the shortening of the treatment duration. All of these factors would improve the patient compliance with chemotherapy of TB.
  17. Sharip S, Michie P, Schall U, Drysdale K, Case V, Sankaranarayanan A, et al.
    Compr Psychiatry, 2013 Oct;54(7):865-72.
    PMID: 23602388 DOI: 10.1016/j.comppsych.2013.03.015
    The present study was undertaken to evaluate the effect of cognitive training in improving trained and untrained cognitive processes in schizophrenia.
    MeSH terms: Activities of Daily Living; Adult; Australia; Cognition*; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Schizophrenia/rehabilitation*; Schizophrenic Psychology*; Social Adjustment; Social Behavior; Social Perception; Cognitive Therapy/methods*; Treatment Outcome; Executive Function*
  18. Basiri A, Murugaiyah V, Osman H, Kumar RS, Kia Y, Ali MA
    Bioorg Med Chem, 2013 Jun 1;21(11):3022-31.
    PMID: 23602518 DOI: 10.1016/j.bmc.2013.03.058
    A series of hitherto unreported pyrido-pyrimidine-2-ones/pyrimidine-2-thiones were synthesized under microwave assisted solvent free reaction conditions in excellent yields and evaluated in vitro for their acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes inhibitory activity. Among the pyridopyrimidine derivatives, 7e and 7l displayed 2.5- and 1.5-fold higher enzyme inhibitory activities against AChE as compared to standard drug, galanthamine, with IC50 of 0.80 and 1.37 μM, respectively. Interestingly, all the compounds except 6k, 7j and 7k displayed higher inhibitory potential against BChE enzyme in comparison to standard with IC50 ranging from 1.18 to 18.90 μM. Molecular modeling simulations of 7e and 7l was performed using three-dimensional structure of Torpedo californica AChE (TcAChE) and human butyrylcholinesterase (hBChE) enzymes to disclose binding interaction and orientation of these molecule into the active site gorge of respective receptors.
    MeSH terms: Acetylcholinesterase/chemistry*; Animals; Butyrylcholinesterase/chemistry*; Cholinesterase Inhibitors/chemical synthesis*; Cholinesterase Inhibitors/chemistry; Galantamine/chemistry; Humans; Microwaves; Pyrimidines/chemical synthesis*; Pyrimidines/chemistry; Structure-Activity Relationship; Torpedo; Catalytic Domain; Molecular Docking Simulation
  19. Ajorlo M, Abdullah RB, Yusoff MK, Halim RA, Hanif AH, Willms WD, et al.
    Environ Monit Assess, 2013 Oct;185(10):8649-58.
    PMID: 23604787 DOI: 10.1007/s10661-013-3201-8
    This study investigates the applicability of multivariate statistical techniques including cluster analysis (CA), discriminant analysis (DA), and factor analysis (FA) for the assessment of seasonal variations in the surface water quality of tropical pastures. The study was carried out in the TPU catchment, Kuala Lumpur, Malaysia. The dataset consisted of 1-year monitoring of 14 parameters at six sampling sites. The CA yielded two groups of similarity between the sampling sites, i.e., less polluted (LP) and moderately polluted (MP) at temporal scale. Fecal coliform (FC), NO3, DO, and pH were significantly related to the stream grouping in the dry season, whereas NH3, BOD, Escherichia coli, and FC were significantly related to the stream grouping in the rainy season. The best predictors for distinguishing clusters in temporal scale were FC, NH3, and E. coli, respectively. FC, E. coli, and BOD with strong positive loadings were introduced as the first varifactors in the dry season which indicates the biological source of variability. EC with a strong positive loading and DO with a strong negative loading were introduced as the first varifactors in the rainy season, which represents the physiochemical source of variability. Multivariate statistical techniques were effective analytical techniques for classification and processing of large datasets of water quality and the identification of major sources of water pollution in tropical pastures.
    MeSH terms: Animal Husbandry/statistics & numerical data; Environmental Monitoring*; Escherichia coli/growth & development; Factor Analysis, Statistical; Feces; Hydrogen-Ion Concentration; Malaysia; Nitrates/analysis; Oxygen/analysis; Rain; Seasons; Water Pollutants, Chemical/analysis*; Water Pollution, Chemical/statistics & numerical data*; Multivariate Analysis; Cluster Analysis; Ecosystem*; Principal Component Analysis; Rivers/microbiology; Rivers/chemistry*; Biological Oxygen Demand Analysis; Water Quality
  20. Lee KS, Yuen KH, Ng WK
    Fish Physiol Biochem, 2013 Dec;39(6):1457-71.
    PMID: 23604920 DOI: 10.1007/s10695-013-9799-1
    Vitamin E, a potent antioxidant consisting of four isomers each (α, β, γ, δ) of tocopherol (T) and tocotrienol (T3), is found naturally in plant oils at different concentrations. In this study, four semi-purified isonitrogenous and isolipidic (10 %) diets containing canola oil, cold-pressed soybean oil, wheat germ oil, or palm fatty acid distillates (PFAD) as the sole vitamin E source were fed to triplicate groups of red hybrid tilapia (Oreochromis sp.) fingerlings (14.82 ± 0.05 g) for 45 days. Vitamin E concentrations and composition were measured in the muscle, liver, skin, and adipose tissue. Deposition of α-T (53.4-93.1 % of total vitamin E) predominated over deposition of other isomers, except in the liver of fish fed the SBO diet, where α-T and γ-T deposition was in the ratio 40:60. T3 deposition (2.6-29.4 %) was only detected in tissues of fish fed the PFAD diet; adipose tissue was the major storage depot. Fish fed the SBO diet contained significantly more (P 
    MeSH terms: Adipose Tissue/metabolism; Animals; Animal Feed/analysis; Body Composition; Fatty Acids/analysis; Liver/metabolism; Muscles/metabolism; Plant Oils*; Random Allocation; Skin/metabolism; Tilapia/growth & development; Tilapia/metabolism*; Thiobarbituric Acid Reactive Substances/metabolism; Aquaculture*; Tocopherols/metabolism*; Tocotrienols/metabolism*
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