Affiliations 

  • 1 University Malaya Medical Center, University Malaya, Division of Respiratory Medicine, Department of Medicine, Lembah Pantai, Kuala Lumpur, Malaysia. scianray@gmail.com
  • 2 Queen Elizabeth Hospital, Respiratory Department, Jalan Penampang, Kota Kinabalu, Sabah, Malaysia
  • 3 Sarawak General Hospital, Department of Medicine, Division of Respiratory Medicine, Jalan Hospital, Kuching, Sarawak, Malaysia
Med J Malaysia, 2024 Jul;79(4):490-493.
PMID: 39086350

Abstract

Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is commonly used to diagnose and stage lung cancer. In clinical practice, cytology specimens from EBUS-TBNA may be low in cellularity, especially with necrotic lesions. Endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) has recently become the preferred method for obtaining histology biopsy. This retrospective cohort study analysed the first 30 patients who have undergone EBUS-TBMC in a tertiary centre in Malaysia. EBUS-TBMC demonstrated a high diagnostic yield and good safety profile. All the samples obtained were adequate for the detection of driver alteration by next-generation sequencing.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.