Fulltext

Boldine improves endothelial function in diabetic db/db mice through inhibition of angiotensin II-mediated BMP4-oxidative stress cascade

Lau YS 1 , Tian XY , Mustafa MR , Murugan D , Liu J , Zhang Y Show all authors , Lau CW , Huang Y

Affiliations 

  • 1 Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Br J Pharmacol, 2013 Nov;170(6):1190-8.
PMID: 23992296 DOI: 10.1111/bph.12350

Abstract

Boldine is a potent natural antioxidant present in the leaves and bark of the Chilean boldo tree. Here we assessed the protective effects of boldine on endothelium in a range of models of diabetes, ex vivo and in vitro.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

MeSH terms
Similar publications