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Changes in Metabolic Hormones in Malaysian Young Adults following Helicobacter pylori Eradication

Yap TW 1 , Leow AH 2 , Azmi AN 2 , Francois F 3 , Perez-Perez GI 4 , Blaser MJ 4 Show all authors , Poh BH 5 , Loke MF 1 , Goh KL 2 , Vadivelu J 1

Affiliations 

  • 1 Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia
  • 2 Department of Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia
  • 3 New York University Cancer Institute, New York University School of Medicine, New York, New York, United States of America; Department of Medicine, New York University School of Medicine, New York, New York, United States of America
  • 4 Department of Medicine, New York University School of Medicine, New York, New York, United States of America; Department of Microbiology, New York University School of Medicine, New York, New York, United States of America
  • 5 BP Healthcare, 30250 Ipoh, Perak, Malaysia
PLoS One, 2015;10(8):e0135771.
PMID: 26291794 DOI: 10.1371/journal.pone.0135771

Abstract

More than half of the world's adults carry Helicobacter pylori. The eradication of H. pylori may affect the regulation of human metabolic hormones. The aim of this study was to evaluate the effect of H. pylori eradication on meal-associated changes in appetite-controlled insulinotropic and digestive hormones, and to assess post-eradication changes in body mass index as part of a currently on-going multicentre ESSAY (Eradication Study in Stable Adults/Youths) study.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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