15-deoxy-isoxeniolide-A, new diterpenoid from a bornean soft coral, Xenia sp

Phan CS 1 , Kamada T 1 , Kobayashi K 2 , Hamada T 2 , Vairappan CS

Affiliations 

  • 1 a Laboratory of Natural Products Chemistry , Institute for Tropical Biology and Conservation, Universiti Malaysia Sabah , Sabah , Malaysia
  • 2 b Graduate School of Science and Engineering , Kagoshima University , Kagoshima , Japan
Nat Prod Res, 2018 Jan;32(2):202-207.
PMID: 28691521 DOI: 10.1080/14786419.2017.1346638

Abstract

A new xenicane diterpenoid, 15-deoxy-isoxeniolide-A (1) along with four known compounds 9-deoxy-isoxeniolide-A (2), isoxeniolide-A (3), xeniolide-A (4) and coraxeniolide-B (5) were isolated from the Bornean soft coral Xenia sp. The structures of these metabolites were elucidated on the basis of spectral analysis, NMR and HRESIMS. Compound 5 showed cytotoxic activity against ATL cell line, S1T.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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