Affiliations 

  • 1 Universiti Kebangsaan Malaysia
  • 2 KPJ Healthcare University College
  • 3 Hospital Kuala Lumpur
Jurnal Sains Kesihatan Malaysia, 2017;15(22):137-144.
MyJurnal

Abstract

Daily food intake of women may affect their bone health by altering their bone mineral density (BMD) as the lack of certain
nutrients may affect bone integrity whilst, BMD also can be a predictor of breast cancer. To date, many studies have been
conducted to discuss on association of BMD and mammographic breast density (MBD) and how both are related to breast
cancer risks but no consideration has been made on dietary intake. Therefore, this study was designed to determine
the association of dietary intake with BMD and other breast cancer risk factors. A cross-sectional study on 76 pre- and
postmenopausal women above 40 years underwent mammogram screening and Dual Energy X-ray Absorptiometry (DEXA)
was conducted in Hospital Kuala Lumpur (HKL) for the duration of 1 year. Purposive sampling method was used to choose
the respondents. Women who are diagnosed with breast cancer and underwent cancer treatment were excluded from this
study. DEXA unit (Hologic Discovery W, Hologic, Inc) were used to measure BMD at the femoral neck and lumbar spine in
grams per centimetre squared (g/cm2
) and they were classified into normal and abnormal group based on the T-scores.
The subjects were asked about their daily dietary pattern for a duration of three days using Diet History Questionnaire
(DHQ). The mean of selected characteristics were compared between groups. Additionally, binary logistic regression was
used to determine the association between diet intake with BMD and other risk factors of breast cancer. The total number
of pre- and postmenopausal women who consented to participate in this study are equal. The mean age was 47.1 years
and 54.9 years for premenopausal and postmenopausal women respectively. The results indicate only menopausal age of
the women was statistically significant (p < 0.05). A number of 17% premenopausal and 9% of postmenopausal women
showed to have family history of breast cancer, however, it was not statistically significant (p = 0.12). There was no
significant difference in daily energy intake of food in both groups (p = 0.22). None of the nutrients in daily food intake
showed to be statistically significant. Menstrual status showed an association with BMD with p < 0.05 and the remaining
risk factors did not show any association. Logistic regression revealed that only menstrual status had correlation with
BMD in both groups. This study provided the dietary pattern and the effects on bone health. The association of other risk
factors of breast cancer with BMD were also analysed and most of it showed a negative association.