In-Hospital Coronary Revascularization Rates and Post-Discharge Mortality Risk in Non-ST-Segment Elevation Acute Coronary Syndrome

Bueno H 1 , Rossello X 2 , Pocock SJ 3 , Van de Werf F 4 , Chin CT 5 , Danchin N 6 Show all authors , Lee SW 7 , Medina J 8 , Huo Y 9

Affiliations 

  • 1 Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain; Instituto de Investigación i+12 and Cardiology Department, Hospital Universitario 12 de Octubre, Madrid, Spain; Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain. Electronic address: hector.bueno@cnic.es
  • 2 Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain; London School of Hygiene and Tropical Medicine, London, United Kingdom; CIBER de Enfermedades CardioVasculares, Madrid, Spain. Electronic address: https://twitter.com/RosselloXavier
  • 3 London School of Hygiene and Tropical Medicine, London, United Kingdom
  • 4 Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium
  • 5 National Heart Centre Singapore, Singapore
  • 6 Hôpital Européen Georges Pompidou & René Descartes University, Paris, France
  • 7 Queen Mary Hospital, Hong Kong SAR, China
  • 8 Global Medical Affairs, AstraZeneca, Madrid, Spain
  • 9 Beijing University First Hospital, Beijing, China
J Am Coll Cardiol, 2019 09 17;74(11):1454-1461.
PMID: 31514947 DOI: 10.1016/j.jacc.2019.06.068

Abstract

BACKGROUND: The relationship between in-hospital coronary revascularization rate (CRR) and post-discharge mortality rates in survivors of non-ST-segment elevation acute coronary syndrome (NSTE-ACS) at a system level is unclear.

OBJECTIVES: The purpose of this study was to evaluate CRR and 2-year post-discharge mortality rate (2YMR) in NSTE-ACS.

METHODS: CRR and 2YMR were analyzed by hospital rate of CRR (in deciles), by country, and by world region in 11,931 patients with NSTE-ACS who survived to discharge and were enrolled in the EPICOR (long-tErm follow uP of antithrombotic management patterns In acute CORonary syndrome patients) and EPICOR Asia: twin multinational, observational, prospective cohort studies.

RESULTS: Significant differences in patient baseline characteristics, medical therapies, CRR, and 2YMR were found. Mean CRR ranged from 0.0% to 96.8% in the first and tenth decile, respectively (p 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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