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Biological Activities of Snowdrop (Galanthus spp., Family Amaryllidaceae)

Kong CK 1 , Low LE 2 , Siew WS 3 , Yap WH 3 , Khaw KY 1 , Ming LC 4 Show all authors , Mocan A 5 , Goh BH 1 , Goh PH 4

Affiliations 

  • 1 Biofunctional Molecule Exploratory (BMEX) Research Group, School of Pharmacy, Monash University Malaysia, Subang Jaya, Malaysia
  • 2 Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
  • 3 School of Biosciences, Taylor's University, Subang Jaya, Malaysia
  • 4 PAPRSB Institute of Health Sciences, Universiti Brunei Darussalam, Gadong, Brunei
  • 5 Department of Pharmaceutical Botany, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
Front Pharmacol, 2020;11:552453.
PMID: 33679383 DOI: 10.3389/fphar.2020.552453

Abstract

Snowdrop is an iconic early spring flowering plant of the genus Galanthus (Amaryllidaceae). Galanthus species (Galanthus spp.) are economically important plants as ornaments. Galanthus spp has gained significance scientific and commercial interest due to the discovery of Galanthamine as symptomatic treatment drug for Alzhiermer disease. This review aims to discuss the bioactivities of Galanthus spp including anticholinesterase, antimicrobial, antioxidant and anticancer potential of the extracts and chemical constituents of Galanthus spp. This review highlights that Galanthus spp. as the exciting sources for drug discovery and nutraceutical development.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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