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  1. Fulltext Nonlinear Control of Fouling in Polyethylene Reactors
    Rohman FS, Othman MR, Muhammad D, Azmi A, Idris I, Ilyas RA, et al.
    ACS Omega, 2022 Nov 08;7(44):39648-39661.
    PMID: 36385840 DOI: 10.1021/acsomega.2c03078
    Fouling formation in reactor vessels poses a serious threat to the safe operation of the industrial low-density polyethylene (LDPE) polymerization. Fouling also degrades the polymer quality and causes productivity loss to some extent. In this work, neural Wiener model predictive control (NWMPC) is introduced to address the fouling concern. In addition, a soft sensor model is used to activate the fouling-defouling (F-D) mechanism when the fouling surpasses the thickness limit to prevent vessel overheating. NWMPC is proven to be fast, stable, and robust under various control scenarios. The use of a soft sensor model in conjunction with NWMPC enables the online monitoring and controlling of the F-D processes. When comparison is made with a state space (SSMPC) utilizing only the linear block, NWMPC is found to be able to control the LDPE grade with quicker grade transition and lower resource consumption.
  2. Fulltext Fluorescence multispectral imaging-based diagnostic system for atherosclerosis
    Ho CS, Horiuchi T, Taniguchi H, Umetsu A, Hagisawa K, Iwaya K, et al.
    Biomed Eng Online, 2016 Aug 20;15(1):98.
    PMID: 27542354 DOI: 10.1186/s12938-016-0220-z
    Composition of atherosclerotic arterial walls is rich in lipids such as cholesterol, unlike normal arterial walls. In this study, we aimed to utilize this difference to diagnose atherosclerosis via multispectral fluorescence imaging, which allows for identification of fluorescence originating from the substance in the arterial wall.
  3. Neuroendoscopy for post-infective hydrocephalus in children
    Deopujari CE, Padayachy L, Azmi A, Figaji A, Samantray SK
    Childs Nerv Syst, 2018 10;34(10):1905-1914.
    PMID: 30099619 DOI: 10.1007/s00381-018-3901-z
    The treatment of hydrocephalus has changed in recent years with better imaging and introduction of endoscopic procedures as well as enhanced shunts. Indications of endoscopic third ventriculostomy (ETV) are now more refined with better quantification of outcome. This article reviews the current state of neuroendoscopy for infective hydrocephalus in children. The roles of third ventriculostomy as a primary procedure or after shunt malfunction, endoscopic interventions in multiloculated hydrocephalus and introduction of intraventricular lavage to salvage severely infected children are evaluated.
  4. Fulltext Data for the industrial and municipal environmental wastes hazard contaminants assessment with integration of RES2D techniques and Oasis Montaj software
    Arifin MH, Kayode JS, Ismail KI, Abdullah M, Embrandiri A, Nazer SM, et al.
    Data Brief, 2020 Dec;33:106595.
    PMID: 33318980 DOI: 10.1016/j.dib.2020.106595
    Industrial, and municipal wastes are part of the main sources of environmental hazards as well as groundwater and surface water pollutions. If not well composed, treated, and safely disposed, it could permeate through the subsurface lithologies by reaching down to the underground water aquifers, particularly in zones of unprotected aquifer units. Pollutants, most especially the landfills leachates that encompassed organic contaminants, ammonia, nitrates, total nitrogen, suspended solids, heavy metals and soluble inorganic salts, i.e., soluble nitrogen, sulphur compound, sulphate and chlorides, could posed undesirable environmental impacts due to inappropriate disposals that may give rise to gaseous fumes and leachate formations. An electrical resistivity geophysical technique utilizing the RES2D no-invasive, cost-effective and rapid method of data collection was integrated with the 3D Oasis Montaj software to approximate the volume of the generated rectangular prism model of the contaminants delineated from mixtures of the industrial, and municipal wastes plumes to be 312,000 m 3.
  5. Fulltext Data for the subsurface characterization of Pahang River Basin with the application of Transient Electromagnetic geophysical surveys
    Arifin H, Kayode J, Arifin K, Zahir Z, Abdullah M, Azmi A
    Data Brief, 2020 Jun;30:105491.
    PMID: 32373680 DOI: 10.1016/j.dib.2020.105491
    The Transient Electro-Magnetic (TEM) geophysical technique was deployed to map and characterized the subsurface of Pahang River Basin along the East Coast Peninsula Malaysia. The data aimed at differentiating between the massive zones and the weak zones within the region, to also assess and differentiate the subsurface structures and comes up with recommendations for policy decision, formulation and plans on the flooding impact, surface water and groundwater managements, in addition to other environmental related issues ravaging the area. The data presented in this paper, showed the properties of the subsurface rocks underlain the region as beneficial to the Agriculturists; Climatologists; Engineers; Environmentalists; Geoscientists, Hydrologists and Policy formulation officers. The TEM data collection utilized a 100 m x 100 m single loop coil for both the Transmitter (Tx) loop and the Receiver (Rx) loop to produce a total surface area coverage of 10,000 m2 per survey line along a single profile. The total area covered in the data extended across an average area of 30 km x 40 km in parts of Maran, Temerloh and Jerantut districts, within the State of Pahang, East Coast, Peninsula Malaysia. The conductivity data recorded varied from -20 mS/m to about 440 mS/m at a maximum depth of about 375 m. On the other hand, the resistivity data recorded varied from 0 Oh-m to about 1000 Oh-m. The information derived from the data are intended for potential abstraction by the Malaysian Groundwater Management Board; the Department of Mineral and Geoscience; Department of Irrigation and Drainage; the Pahang State Water Board, and the Department of Agriculture.
  6. Assessing quality of a worksite health promotion programme from participants' views: findings from a qualitative study in Malaysia
    Liau SY, Hassali MA, Shafie AA, Ibrahim MI
    Health Expect, 2014 Feb;17(1):116-28.
    PMID: 22050457 DOI: 10.1111/j.1369-7625.2011.00742.x
    An assessment of the process and outcomes of a health promotion programme is necessary for the continuous improvement of a programme.
  7. Fulltext Compatible extension of the (G'/G)-expansion approach for equations with conformable derivative
    Al-Shawba AA, Abdullah FA, Azmi A, Akbar MA, Nisar KS
    Heliyon, 2023 May;9(5):e15717.
    PMID: 37206045 DOI: 10.1016/j.heliyon.2023.e15717
    In this study, the compatible extensions of the (G'/G)-expansion approach and the generalized (G'/G)-expansion scheme are proposed to generate scores of radical closed-form solutions of nonlinear fractional evolution equations. The originality and improvements of the extensions are confirmed by their application to the fractional space-time paired Burgers equations. The application of the proposed extensions highlights their effectiveness by providing dissimilar solutions for assorted physical forms in nonlinear science. In order to explain some of the wave solutions geometrically, we represent them as two- and three-dimensional graphs. The results demonstrate that the techniques presented in this study are effective and straightforward ways to address a variety of equations in mathematical physics with conformable derivative.
  8. The effect of tailored consumer medicine information on patients with type 2 diabetes mellitus: A randomised controlled interventional study
    Munsour EE, Awaisu A, Hassali MAA, Abdoun E, Dabbous Z, Zahran N, et al.
    Int J Clin Pract, 2020 Aug;74(8):e13527.
    PMID: 32386077 DOI: 10.1111/ijcp.13527
    INTRODUCTION: In patients with diabetes, better health communication is associated with better health outcomes including medication adherence and glycaemic control. The conventional patient information leaflet does not consider the cultural and behavioral perspectives of diverse patient populations. Consumer medicine information (CMI) is a written information about the prescription drugs developed by organisations or individuals other than a drug manufacturer that is intended for distribution to consumers at the time of medication dispensing.

    OBJECTIVE: This study aimed to evaluate the impact of CMI on medication adherence and glycaemic control among patients with type 2 diabetes in Qatar.

    METHODS: We developed and customised CMI for all the anti-diabetic medications used in Qatar. A randomised controlled trial in which the intervention group patients (n = 66) received the customised CMI with usual care, while the control group patients (n = 74) received usual care only, was conducted. Self-reported medication adherence and haemoglobin A1c (HbA1c ) were the primary outcome measures. Glycaemic control and medication adherence parameters were measured at baseline, 3 months, and 6 months in both groups. Medication adherence was measured using the 8-item Morisky Medication Adherence Scale (MMAS-8).

    RESULTS: Although the addition of CMI resulted in better glycaemic control, this did not reach statistical significance, possibly because of the short-term follow-up. The median MMAS-8 score improved from baseline (6.6 [IQR = 1.5]) to 6-month follow-up (7.0 [IQR = 1.00]) in the intervention group. In addition, there was a statistically significant difference between the intervention and the control groups in terms of MMAS-8 score at the third visit (7.0 [IQR = 1.0]) vs 6.5 (IQR = 1.25; P-value = .010).

    CONCLUSION: CMI for anti-diabetic medications when added to usual care has the potential to improve medication adherence and glycaemic control among patients with type 2 diabetes. Therefore, providing better health communication and CMI to patients with diabetes is recommended.

  9. Engineered liposomes mediated approach for targeted colorectal cancer drug Delivery: A review
    Shazleen Ibrahim I, Starlin Chellathurai M, Mahmood S, Hakim Azmi A, Harun N, Ulul Ilmie Ahmad Nazri M, et al.
    Int J Pharm, 2024 Feb 15;651:123735.
    PMID: 38142874 DOI: 10.1016/j.ijpharm.2023.123735
    Colorectal cancer (CRC) continues to be one of the most prevalent and deadliest forms of cancer worldwide, despite notable advancements in its management. The prognosis for metastatic CRC remains discouraging, with a relative 5-year survival rate for stage IV CRC patients. Conventional treatments for advanced malignancies such as chemotherapy, often face limitations in effectively targeting cancer cells resulting in off-target distribution and significant side effects. In the quest for better strategies, researchers have explored numerous alternatives. Among these, nanoparticles (NPs) specifically liposomes have emerged as one of the most promising candidates in developing targeted delivery systems for cancer therapeutics. This review discusses the current approaches employing functionalised liposomes to overcome major biological barriers in therapeutics delivery for CRC treatment. We have also shared our perspectives on the technological development of liposomes for future clinical use and highlighted a few useful insights on the material choices for future research work in CRC.
  10. Fulltext Environmental hazard assessment of industrial and municipal waste materials with the applications of RES2-D method and 3-D Oasis Montaj modeling: A case study at Kepong, Kuala Lumpur, Peninsula Malaysia
    Arifin MH, Kayode JS, Ismail MKI, Abdullah AM, Embrandiri A, Nazer NSM, et al.
    J Hazard Mater, 2021 03 15;406:124282.
    PMID: 33199149 DOI: 10.1016/j.jhazmat.2020.124282
    Environmental hazards, industrial, and municipal wastes geochemical and geophysical assessments were carried out at an industrial waste disposal (IWD) site at Bukit Kepong, Kuala Lumpur, Malaysia. RES2-D geophysical method was applied, capable of identification and quantification of the industrial wastes; buried hazardous materials (BHM) and their effects on the subsurface stratum, from the moderately saturated zones, to fully saturated zones housing the aquifer units underneath the water table. Six RES2-D survey profiles were respectively acquired along E-W, and N-S directions. The perpendicular arrangement of the RES2-D survey lines, was tenaciously designed to make possible, the industrial waste materials (IWM)and municipal solid waste (MSW) quantification, with sufficient length of survey lines set at 200 m, and electrode spacing of 5 m, to cover as much details segments of the IWM and MSW as possible. The six RES2-D inversion results, helped in the subsurface stratum classification into three layers, namely; soft layers, which encompasses the waste materials, with varied resistivity values i.e., 0-100 Ω-m, at 10-15 m depths. The consolidated layers produced varied resistivity values i.e., 101-400 Ω-m, at 15-20 m depths. The bedrock has the highest resistivity values i.e., 401-2000 Ω-m, at depths > 20 m. The estimated volume of the waste materials was 312,000 m 3, using 3-D Oasis Montaj modeling via rectangular prism model generated from the inverted RES2-D. Results from the geochemical analysis helped in the validation of the site as a potential contaminated zone with severe health effects.
  11. Fulltext Kajian audit keselamatan dan kesihatan pekerjaan terhadap aspek fizikal di Kolej Kediaman Dato’ Onn, UKM
    Kadir, A., Kadaruddin, A., Shaharuddin, A., Azahan, A., Muhammad Rizal, R., Lukman, Z.M., et al.
    Malaysian Journal of Community Health, 2011;17(1):9-17.
    MyJurnal
    Background: Safety and health audit study is a part of occupational safety and health risk assesment. Thus, student’s residential audit is important in order tu ensure the safety rules which implemented by the management is appropriate and follow the standard set forth. Furthermore, it also important to determine places, area or situation that might lead to hazard risk so that prevention step could be plan and implement.

    Objective: This study was to determine the safety level of students residential in physical aspects.

    Methods: Safety inspection or audit conducted is in accordance with criteria and indicators listed in the checklists that have been formed based on the audit forms from the Department of Safety and Health (DOSH), National Institute of Safety and health (NIOSH) and the Occupational Safety and Health Committee of UKMs (JKKP). Several indicators are also included in the audit form as to ensure it covers all the technical aspect and suited with the college conditions. The safety level for each of the blocks in KDO is categorized using points and percentage score obtained.

    Results: Based on the overall score, the average safety score in percentage for areas in KDO are preceded by general office with score 85.5% followed by residential blocks with 71.5%, facilities with score 71.2% and administration block with 70.9%. The results of the study show that most of the areas are at least in a safe level.

    Conclusion: Roles of employer and college administration, significant OSH programme and safety audit are important factors as to ensure the safety of student's residential college.
  12. Fulltext Helminthiasis among primary rural school children in Bachok, Kelantan
    Anees, A.H., Zulkifli, A., Azmi, A., Syukri, M.
    Malaysian Journal of Public Health Medicine, 2003;3(2):19-22.
    MyJurnal
    A cross-sectional study on helminthiasis among rural primary schoolchildren aged 9 to 10 years Bachok, Kelaritan was perfumed. A total of 680 schoolchildren participated in the study. Stool specimens were examined for the presence of the ova of Ascaris lumbricoides, Trichuris trichiura and hoolcwonn. The worm load was then measured using the modified Stoll`s volumetric dilution
    technique. The overall prevalence of helminthiasis was 77 .2%. Trichuris trichiura were the commonest type of heminth noted - 66.8%, compared with Ascaris lumlrricoides (49.7%) and hookworm (1.8%). Mixed infections with Ascaris lumlyricoides and Trichuris trichiura was the commonest type of infection 249(41 .5%) . For Ascaris lumbncoides, 34.6% had mild and 5 I .3% had moderate worm load while for Trichurb trichiura, 66.5% had mild and 30.8 % had moderate worm load. Only 14.1% and 2.7% 4 of the schoolchildren had a heavy load of Ascaris lumlwicoides and Trichuris trichiura respectively. All the schookhildren with hookworm were only mildly infected. Targeted mass treatment for rural Mahysian schoolchildren is still essential, especially in areas where poverty and malnutrition are still prevalent.
  13. Fulltext Three-year follow-up of a Traumatic Hemipelvectomy Survivor: A Case Report
    Wan KL, Azlan MS, Syed-Azmi AS, Lattish R, Faisham WI
    Malays Orthop J, 2021 Nov;15(3):143-146.
    PMID: 34966511 DOI: 10.5704/MOJ.2111.024
    The management of a patient with traumatic hemipelvectomy is complex. We report the acute management and rehabilitation of a 21-year-old patient as well as her prosthesis modification. She was able to return to society as a K3 level ambulator.
  14. Fulltext A novel method for the quantification of industrial and municipal waste materials for environmental hazard assessment
    Arifin MH, Kayode JS, Ismail MKI, Abdullah AM, Embrandiri A, Nazer NSM, et al.
    MethodsX, 2021;8:101182.
    PMID: 33365262 DOI: 10.1016/j.mex.2020.101182
    A novel methodological approach was developed to quantified the volume of industrial waste desposal (IWD) site, combined with municipal waste materials (MWM), through the integration of a non-invasive, fast, and less expenssive RES2-D Electrical Resistivity Technique (ERT), using Wenner-Schlumberger electrode array geophysical method with Oasis Montaj software. Underground water bearing structures, and the eco-system are being contaminated through seepage of the plumes emanating from the mixtures of the industrial waste materials (IWM), made of moist cemented soil with municipal solid wastes (MSW) dumped at the site. The distribution of the contiminant hazardous plumes emanating from the waste materials' mixtures within the subsurface structural lithological layers was clearly map and delineated within the near-surface structures, using the triplicate technique to collect samples of the soil with the waste mixtures, and the water analysis for the presence of dissolved ions. The deployed method helped to monitor the seepage of the contaminant leachate plumes to the groundwater aquifer units via the ground surface, through the subsurface stratum lithological layers, and hence, estimation of the waste materials' volume was possibly approximated to be 312,000 m3. In summary, the novel method adopted are as presented below:•The novel method is transferable, reproduce-able, and most importantly, it is unambiguous technique for the quantification of environmental, industrial and municipal waste materials.•It helps to map the distribution of the plumes emanating from the waste materials' mixtures within the subsurface structural lithological layers that was clearly delineated within the near-surface structures underlain the study site.•The procedure helped in the monitoring of leachate contaminants plumes seepages into the surface water bodies and the groundwater aquifer units, via the ground surface, through to the porous subsurface stratum lithological layers.
  15. Spermatic cord metastasis from a medulloblastoma
    Thambi dorai CR, Azmi A, Rahman AJ, Subathra S, Hayati AR, Zulfiqar A
    Pediatr Surg Int, 2001 Nov;17(8):654-6.
    PMID: 11727063
    A 4-year-old boy presented with metastases in the spermatic cord and ribs 2 years after treatment for a primary medulloblastoma (MB). The testis was free of tumor. A MB presenting with a metastasis to the spermatic cord has not been reported to date. The role of a ventriculo-peritoneal shunt in promoting such spread should be considered in planning management.
  16. Fulltext Assessment of transformer health index using different model
    Jasni, J., Azmi, A., Azis, N., Yahaya, M.S., Talib, M.A.
    Pertanika Journal of Science & Technology, 2017;25(102):143-150.
    MyJurnal
    Transformer failures lead to interruption of power supply. Therefore, asset management is important to monitor the efficient functioning of transformers. An important approach in asset management is condition assessment whereby the health status of the transformer is assessed via a health index. There are many methods in determining the final value of a health index. This paper examines how different assessment methods can be used in order to come up with the final health index and output of final health index. The output trend shapes are almost the same for Assessment Model A, B and C except for Assessment Model D. There is no strong correlation between the health index and age of the transformer. Generally, the value of health index of the transformer is reflected by its operation and loading history .This paper hence examines the assessment steps and results that will guide the development of a new approach to determine health index value.
  17. Fulltext General formula for calculating accumulated amount based on average lowest balance concept
    Wahab, Z.A., Embong, R., Isa, N.B.M., Azmi, A.
    Pertanika Journal of Science & Technology, 2018;26(1):317-328.
    MyJurnal
    One of the ways to calculate dividend for an investment is by using average lowest balance (ALB) concept. The existing calculation of dividend based on ALB concept can only be done yearly. This paper discusses on the development of a general formula to calculate the accumulated amount for any period of time, based on the ALB concept that considers different yearly dividend rates. The patterns for each variable and coefficient for the calculated yearly accumulated amount were analysed. The general forms of each variable and coefficient were then combined to form the general formula for calculating the accumulated amount. Validity of the general formula is confirmed by calculating the percentage errors and proven by using mathematical induction.
  18. Fulltext Liver protective effect of chloroform extract of Bauhinia purpurea leaves is attributed partly to its antioxidant action and the presence of flavonoids
    Zakaria ZA, Sahmat A, Hizami Azmi A, Zainol ASN, Omar MH, Balan T, et al.
    Pharm Biol, 2023 Dec;61(1):1152-1161.
    PMID: 37559390 DOI: 10.1080/13880209.2023.2241510
    CONTEXT: Bauhinia purpurea L. (Fabaceae) is used in the Ayurvedic system to treat various oxidative-related ailments (e.g., wounds, ulcers etc.). Therefore, it is believed that the plant also has the potential to alleviate oxidative-related liver damage.

    OBJECTIVE: This study elucidates the hepatoprotective activity of chloroform extract of B. purpurea leaves (CEBP) in paracetamol (PCM)-induced liver injury (PILI) rats.

    MATERIALS AND METHODS: Male Sprague-Dawley rats (n = 6) were pre-treated once daily (p.o.) with CEBP (50-500 mg/kg) for seven consecutive days before being administered (p.o.) a hepatotoxic agent, 3 g/kg PCM. Liver enzyme levels were determined from the collected blood, while the collected liver was used to determine the activity of endogenous antioxidant enzymes and for histopathological examination. CEBP was also subjected to radical scavenging assays and phytochemical analysis.

    RESULTS: CEBP significantly (p 

  19. Surface Modified Nanocellulose and Its Reinforcement in Natural Rubber Matrix Nanocomposites: A Review
    Hakimi NMF, Lee SH, Lum WC, Mohamad SF, Osman Al Edrus SS, Park BD, et al.
    Polymers (Basel), 2021 Sep 24;13(19).
    PMID: 34641056 DOI: 10.3390/polym13193241
    Natural rubber is of significant economic importance owing to its excellent resilience, elasticity, abrasion and impact resistance. Despite that, natural rubber has been identified with some drawbacks such as low modulus and strength and therefore opens up the opportunity for adding a reinforcing agent. Apart from the conventional fillers such as silica, carbon black and lignocellulosic fibers, nanocellulose is also one of the ideal candidates. Nanocellulose is a promising filler with many excellent properties such as renewability, biocompatibility, non-toxicity, reactive surface, low density, high specific surface area, high tensile and elastic modulus. However, it has some limitations in hydrophobicity, solubility and compatibility and therefore it is very difficult to achieve good dispersion and interfacial properties with the natural rubber matrix. Surface modification is often carried out to enhance the interfacial compatibilities between nanocellulose and natural rubber and to alleviate difficulties in dispersing them in polar solvents or polymers. This paper aims to highlight the different surface modification methods employed by several researchers in modifying nanocellulose and its reinforcement effects in the natural rubber matrix. The mechanism of the different surface medication methods has been discussed. The review also lists out the conventional filler that had been used as reinforcing agent for natural rubber. The challenges and future prospective has also been concluded in the last part of this review.
  20. Fulltext Incidence of Healthcare-Associated Infections (HAIs) and the adherence to the HAIs' prevention strategies in a military hospital in Alkharj
    Ahmed NJ, Haseeb A, Elazab EM, Kheir HM, Hassali AA, Khan AH
    Saudi Pharm J, 2021 Oct;29(10):1112-1119.
    PMID: 34703364 DOI: 10.1016/j.jsps.2021.08.012
    Background: Healthcare-associated infections (HAI) are considered one of the most common adverse events in health care service provision. In order to prevent the occurrence of HAIs, it is important to implement several prevention strategies.

    Objectives: This study aims to determine the incidence of healthcare-associated infections in a military hospital in Alkharj and the adherence to the HAIs' prevention strategies.

    Methods: This study included exporting data for all infected cases confirmed by the infection disease specialists in 2019. The data were collected from the reports that were written by infection control unit and infectious disease department.

    Results: The rate of healthcare associated infections (HAIs) in 2019 was 0.43% of total patient admissions. The rate of central line associated bloodstream infections in 2019 was 1.15 per 1000 central line days. The rate of catheter associated urinary tract infections in 2019 was 1.00 per 1000 catheter days. The rate of ventilator associated pneumonia in 2019 was 2.11 per 1000 ventilator days and the rate of surgical site infections in 2019 was 0.41 %.

    Conclusion: The rate of overall healthcare-associated infections (HAI) was low. The compliance rate of health care workers to preventive measures that control HAIs was generally high but there was a need for more awareness particularly regarding personal protective equipment and hand hygiene. So it is important to attend more awareness activities and workshops particularly regarding personal protective equipment and hand hygiene. Furthermore, infection control unit and infectious disease department in the hospital should support the robust HAI prevention programs.

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