Displaying publications 241 - 260 of 1133 in total

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  1. Paul M, Kalimuthu S, Banu C, Marimuthu S
    Trauma Case Rep, 2018 Dec;18:5-7.
    PMID: 30505922 DOI: 10.1016/j.tcr.2018.11.002
    Penetrative neck injury can cause potentially fatal damage to the neck. Removing those fully embedded small foreign bodies secondary to ballistic trauma can be technically challenging. Neck exploration under direct vision may cause more local tissue damage or dislodge the foreign body further. We discussed a case where a small foreign body embedded in the neck caused by ballistic trauma. Successful removal of the foreign body guided by rigid endoscope thru the neck wound was also discussed as a useful tool as it was not ferromagnetic and image intensifier was not available.
    Matched MeSH terms: Neck Injuries
  2. Anjum A, Yazid MD, Fauzi Daud M, Idris J, Ng AMH, Selvi Naicker A, et al.
    Int J Mol Sci, 2020 Oct 13;21(20).
    PMID: 33066029 DOI: 10.3390/ijms21207533
    Spinal cord injury (SCI) is a destructive neurological and pathological state that causes major motor, sensory and autonomic dysfunctions. Its pathophysiology comprises acute and chronic phases and incorporates a cascade of destructive events such as ischemia, oxidative stress, inflammatory events, apoptotic pathways and locomotor dysfunctions. Many therapeutic strategies have been proposed to overcome neurodegenerative events and reduce secondary neuronal damage. Efforts have also been devoted in developing neuroprotective and neuro-regenerative therapies that promote neuronal recovery and outcome. Although varying degrees of success have been achieved, curative accomplishment is still elusive probably due to the complex healing and protective mechanisms involved. Thus, current understanding in this area must be assessed to formulate appropriate treatment modalities to improve SCI recovery. This review aims to promote the understanding of SCI pathophysiology, interrelated or interlinked multimolecular interactions and various methods of neuronal recovery i.e., neuroprotective, immunomodulatory and neuro-regenerative pathways and relevant approaches.
    Matched MeSH terms: Spinal Cord Injuries/metabolism*; Spinal Cord Injuries/pathology; Spinal Cord Injuries/therapy
  3. Siang PG, Ying XT, Dayang Suhana AM, Ing PT
    Med J Malaysia, 2020 05;75(3):281-285.
    PMID: 32467545
    INTRODUCTIONS: Facial nerve palsy (FNP) occurs in 7-10% of temporal bone fractures. The aim of this study was to review the surgical outcome of nine patients with severe to complete traumatic facial nerve (FN) injury.

    METHODS: The patients were evaluated clinically and FNP was graded using the House Brackmann (HB) scale. High resolution computerized tomography (HRCT) of the temporal bone was used to evaluate temporal bone fractures. Transmastoid facial nerve decompression was performed and the facial nerve function was re-evaluated in subsequent follow ups.

    RESULTS: There were five cases with immediate onset and four with delayed onset of FNP. Only three cases had pure temporal bone fractures, the others were associated with other life threatening injuries. The sensitivity and specificity of HRCT temporal bone to detect the obvious facial canal fracture line were 50% and 40% respectively. 75% of patients with immediate onset of HB grade VI FN palsy who were operated within a month recovered completely. Surgeries for the delayed onset FNP were performed at a mean of 70 days (range 51-94). All recovered to HB grade II-III from severe FNP.

    CONCLUSIONS: Our study demonstrated that transmastoid FN decompression surgery was beneficial to traumatic nerve injury. Early intervention resulted in better outcomes. However, FN function could still be salvaged even in delayed FN decompression.

    Matched MeSH terms: Wounds and Injuries/surgery; Facial Nerve Injuries/surgery*
  4. Lim FT, Ogawa S, Parhar IS
    Brain Res, 2016 11 01;1650:60-72.
    PMID: 27568467 DOI: 10.1016/j.brainres.2016.08.033
    Injury to neuronal tissues in the central nervous system (CNS) of mammals results in neural degeneration and sometime leads to loss of function, whereas fish retain a remarkable potential for neuro-regeneration throughout life. Thus, understanding the mechanism of neuro-regeneration in fish CNS would be useful to improve the poor neuro-regenerative capability in mammals. In the present study, we characterized a neuro-regenerative process in the brain of a cichlid, tilapia, Oreochromis niloticus. Morphological observations showed that the damaged brain region (habenula) successfully regrew and reinnervated axonal projections by 60 days post-damage. A fluorescent carbocyanine tracer, DiI tracing revealed a recovery of the major neuronal projection from the regenerated habenula to the interpenduncular nucleus by 60 days post-damage. TUNEL assay showed a significant increase of apoptotic cells (~234%, P<0.01) at one day post-damage, while the number of bromodeoxyuridine (BrdU)-positive proliferative cells were significantly increased (~92%, P<0.05) at 7 days post-damage compared with sham-control fish. To demonstrate a potential role of apoptotic activity in the neuro-regeneration, effects of degenerative neural tissue on cell proliferation were examined in vivo. Implantation of detached neural but not non-neural tissues into the cranial cavity significantly (P<0.01) increased the number of BrdU-positive cells nearby the implantation regions at 3 days after the implantation. Furthermore, local injection of the protein extract and cerebrospinal fluid collected from injured fish brain significantly induced cell proliferation in the brain. These results suggest that factor(s) derived from apoptotic neural cells may play a critical role in the neuro-regeneration in teleost brain.
    Matched MeSH terms: Brain Injuries/metabolism*; Brain Injuries/physiopathology; Brain Injuries/therapy
  5. Aimanan K, Chea CH, Lim KY, Damodaran A
    BMJ Case Rep, 2019 May 24;12(5).
    PMID: 31129637 DOI: 10.1136/bcr-2018-228255
    Pseudoaneurysm of the ankle involving the posterior tibial artery is a rare presentation with only four paediatric cases previously reported in English literature. We report a new case following blunt trauma with the clinical presentation and management strategy. A 6-year-old boy presented with a pulsatile swelling at the medial aspect of ankle following a history of blunt trauma 3 weeks ago. Imaging confirmed pseudoaneurysm involving the distal posterior tibial artery. Excision of the pseudoaneurysm was performed without any complication.
    Matched MeSH terms: Ankle Injuries/complications; Tibial Arteries/injuries
  6. Ismail, M.S., Fareena, Z.
    Medicine & Health, 2020;15(1):294-299.
    MyJurnal
    Aspirasi bendasing boleh mengancam nyawa. Presentasi yang tidak tipikal dan kekurangan pengimejan diagnostik, telah membuatkan kecurigaan klinikal adalah penting. Kami ingin melaporkan kes aspirasi bendasing dalam seorang dewasa yang hadir ke Jabatan Kecemasan dalam keadaan yang tidak sedarkan diri. Lelaki berusia 31 tahun yang lumpuh disebabkan oleh keretakkan ‘cervical 7th fracture’ dihantar ke Jabatan Kecemasan selepas tidak sedarkan diri dan mengalami penurunan peratusan oksigen disebabkan oleh aspirasi bendasing. Ini adalah kes atipikal aspirasi bendasing pada pesakit yang berjaya didiagnosis dan dirawat menggunakan bronkoskopi fleksibel di Jabatan Kecemasan. Aspirasi bendasing pada orang dewasa sering diabaikan terutama jika ia tidak menyebabkan sesak nafas. Indeks kecurigaan yang tinggi diperlukan terutamanya untuk pesakit berisiko tinggi yang menunjukkan simptom atipikal. Bronkoskopi fleksibel dan ‘rigid’ adalah kaedah diagnosis dan rawatan pesakit yang disyaki aspirasi bendasing. Kesimpulannya, pelbagai jenis penemuan klinikal aspirasi bendasing yang tidak aspirasi dalam saluran udara pada orang dewasa telah dipaparkan. Faktor diagnostik yang paling penting adalah indeks klinikal curiga yang tinggi. Walaupun bronkoskopi ‘rigid’ terus menjadi instrumen pilihan untuk menghilangkan bendasing yang tidak aspisasi di saluran udara orang dewasa, tetapi bronkoskop optik gentian optik juga boleh digunakan dalam keadaan yang tertentu.
    Matched MeSH terms: Neck Injuries
  7. Hanifah J, Paiman M, Nawfar AS, Tengku-Muzaffar T, Wan-Azman WS, Faisham WI, et al.
    Malays Orthop J, 2015 Nov;9(3):61-64.
    PMID: 28611914 MyJurnal DOI: 10.5704/MOJ.1511.014
    High velocity pelvic injury with limb vascular injury poses difficulties as immediate surgery for limb reperfusion is indicated. However immediate vascular intervention deviates from conventional principles of damage control following major injuries. We present two cases of this rare combination of injuries. In both cases, early limb revascularization is possible despite presented with multiple injuries and pelvic fracture.
    Matched MeSH terms: Vascular System Injuries
  8. Ling TH, Zakaria AF, Abdullah AT
    J Orthop Surg (Hong Kong), 2017 01;25(1):2309499017690459.
    PMID: 28228050 DOI: 10.1177/2309499017690459
    Neck manipulation is associated with spinal cord injury. However, occurrence of such cases is infrequent. This article presents a 33-year-old gentleman who sustained acute tetraplegia after neck manipulation. The aim of this case report is to create awareness that vigorous neck manipulation could cause injury to the spinal cord.
    Matched MeSH terms: Cervical Vertebrae/injuries*; Spinal Cord Injuries/etiology*
  9. Iqbal QM
    Med J Malaysia, 1977 Mar;31(3):252-5.
    PMID: 904523
    Matched MeSH terms: Hand Injuries/epidemiology; Leg Injuries/epidemiology
  10. Juanna Bahadun, Abou-Hamden, Amal, Anderson, Peter J.
    MyJurnal
    Paediatric facial traumas are often accompanied by other intracranial and non-head injuries. Use of
    Computed Tomography (CT) has increased diagnostic accuracy when compared to plain radiographs alone. Coexisting anomalies can sometimes be a chance finding from the imagings and this highlights the need of a formalreporting by a radiologist. We report a case of a traumatic unilateral condylar fracture with a coexisting life-threatening abnormality detected from careful assessment of the imagings.
    Matched MeSH terms: Facial Injuries
  11. Delikan AE, Namazie M
    Med J Malaysia, 1979 Sep;34(1):42-5.
    PMID: 542150
    Matched MeSH terms: Brain Injuries/therapy*; Brain Stem/injuries
  12. Noor Azlinda Ahmad, Zawani Amirah Rasid, Zuraimy Adzis
    MyJurnal
    Lightning is among the most deadly natural phenomena to mankind. This phenomenon
    is seen to increase globally as well as in Malaysia. Lightning does strike open areas
    such as playing fields and playgrounds and these areas are places people gather.
    Sensors that can detect the early occurrence of lightning have been developed for
    detecting approaching lightning activity in this project. The main objective is to provide
    early lightning warning system to the public and hence to reduce the number of
    fatalities due to lightning strike. The warning circuit was designed and simulated using
    Multism11. Basic operational method of the circuit is based on the comparative
    voltage method using LM339N integrated circuit comparator (IC). Light Emitting Diodes
    (LEDs) were used as indicators to indicate if the incoming voltage level is higher or
    lower than that of the safety level.
    Matched MeSH terms: Lightning Injuries
  13. Radin Umar RZ, Sommerich CM, Lavender SA, Sanders E, Evans KD
    Ergonomics, 2018 Sep;61(9):1173-1186.
    PMID: 29757713 DOI: 10.1080/00140139.2018.1475016
    Sound workplace ergonomics and safety-related interventions may be resisted by employees, and this may be detrimental to multiple stakeholders. Understanding fundamental aspects of decision-making, behavioural change, and learning cycles may provide insights into pathways influencing employees' acceptance of interventions. This manuscript reviews published literature on thinking processes and other topics relevant to decision making and incorporates the findings into two new conceptual frameworks of the workplace change adoption process. Such frameworks are useful for thinking about adoption in different ways and testing changes to traditional intervention implementation processes. Moving forward, it is recommended that future research focuses on systematic exploration of implementation process activities that integrate principles from the research literature on sense-making, decision-making, and learning processes. Such exploration may provide the groundwork for development of specific implementation strategies that are theoretically grounded and provide a revised understanding of how successful intervention adoption processes work. Practitioner summary: Adoption and acceptance of workplace changes may be facilitated through sound implementation strategies. This manuscript explores several principles of sense-making and decision-making processes that can potentially be used by industrial practitioners to inform the design and development of implementation strategies for interventions that improve workplace ergonomics and safety.

    ABBREVIATIONS:  Musculoskeletal Disorders (MSDs); National Institute for Occupational Safety and Health (NIOSH); National Occupational Research Agenda (NORA); Health and Safety Executive (HSE).

    Matched MeSH terms: Musculoskeletal System/injuries; Occupational Injuries/prevention & control*
  14. Hazwan Ab. Wahid, Kow, Ren Yi, Khan, Ed Simor, Komahen, Colin
    MyJurnal
    The occurrence of atlantoaxial rotatory subluxation is fairly uncommon; however, it is
    more common to be encountered in the paediatric population, typically seen after a
    retropharyngeal inflammation or after a minor trauma. Ligamentous laxity, shallower
    and more horizontally oriented facet joints especially at the C1-2 joint making them
    prone to have atlantoaxial subluxation or dislocation. (Copied from article).
    Matched MeSH terms: Spinal Injuries
  15. Syarifah Aisyah, S.A.H., Elvy Suhana, M.R., Srijit, D., Norzana, A.G.
    Medicine & Health, 2016;11(2):117-130.
    MyJurnal
    Ankle injuries are commonly seen in various sports. The main aim of the present
    review was to highlight the normal anatomy of the ankle, mechanism of injuries
    related to sports, congenital abnormalities or anatomical variations related to
    ankle injury and discuss its effective management. A review of literature was done
    to determine the ankle injuries which occur as a result of various sports related
    activities. We documented all sports which involved injury to the ankle joint. The
    anatomy of various structures in the sole of foot and their involvement in injuries
    were discussed at length. The anatomical knowledge of ankle injury may be
    beneficial for future diagnosis and treatment purpose.
    Matched MeSH terms: Ankle Injuries
  16. Mohd Azimie Ahmad, Norazura Ismail, Mohamad Rizza Othman
    MyJurnal
    The trends of safety incident process have been put in the statistical research and development in order to prevent
    and mitigate the phenomenon. One of the incidents is known as dust explosion. It represents a constant hazard to
    industries which includes any manufacturing using and handling combustible dust materials. Lack of sharing and
    know-how on best practices in managing the workplace must be avoided throughout the industries. The severity and
    the consequences of not taking the safety precautions at workplace have not been foreseen by the process team. This
    present paper discusses the best practices in managing the hazards from the catastrophes to happen again. In addition,
    the mitigation response has also been explored thoroughly through database of best practices.
    Matched MeSH terms: Blast Injuries
  17. Ting FF, Sim KS, Lim CP
    Comput Med Imaging Graph, 2018 11;69:82-95.
    PMID: 30219737 DOI: 10.1016/j.compmedimag.2018.08.011
    Computed Tomography (CT) images are widely used for the identification of abnormal brain tissues following infarct and hemorrhage of a stroke. The treatment of this medical condition mainly depends on doctors' experience. While manual lesion delineation by medical doctors is currently considered as the standard approach, it is time-consuming and dependent on each doctor's expertise and experience. In this study, a case-control comparison brain lesion segmentation (CCBLS) method is proposed to segment the region pertaining to brain injury by comparing the voxel intensity of CT images between control subjects and stroke patients. The method is able to segment the brain lesion from the stacked CT images automatically without prior knowledge of the location or the presence of the lesion. The aim is to reduce medical doctors' burden and assist them in making an accurate diagnosis. A case study with 300 sets of CT images from control subjects and stroke patients is conducted. Comparing with other existing methods, the outcome ascertains the effectiveness of the proposed method in detecting brain infarct of stroke patients.
    Matched MeSH terms: Brain Injuries
  18. Abdullahi D, Ahmad Annuar A, Sanusi J
    Ultrastruct Pathol, 2019;43(6):273-289.
    PMID: 31779507 DOI: 10.1080/01913123.2019.1695693
    Spinal cord injury (SCI) results from penetrating or compressive traumatic injury to the spine in humans or by the surgical compression of the spinal cord in experimental animals. In this study, the neuroprotective potential of Spirulina platensis was investigated on ultrastructural and functional recovery of the spinal cord following surgical-induced injury. Twenty-four Sprague-Dawley rats were divided into three groups; sham group, control (trauma) group, and experimental (S. platensis) group (180 mg/kg) of eight rats each. For each group, the rats were then subdivided into two groups to allow measurement at two different timepoints (day 14 and 28) for the microscopic analysis. Rats in the control and experimental S. platensis groups were subjected to partial crush injury at the level of T12 with Inox number 2 modified forceps by compressing on the spinal cord for 30 s. Pairwise comparisons of ultrastructural grading mean scores difference between the control and experimental S. platensis groups reveals that there were significant differences on the axonal ultrastructure, myelin sheath and BBB Score on Day 28; these correlate with the functional locomotor recovery at this timepoint. The results suggest that supplementation with S. platensis induces functional recovery and effective preservation of the spinal cord ultrastructure after SCI. These findings will open new potential avenue for further research into the mechanism of S. platensis-mediated spinal cord repair.
    Matched MeSH terms: Pyramidal Tracts/injuries; Spinal Cord Injuries/pathology*
  19. Amar Singh HSS, Krishnan R
    Family Physician, 1993;5:54-56.
    Matched MeSH terms: Wounds and Injuries
  20. Das S, Palaniandy K, Abu Bakar A, Idris Z, Abdullah JM
    Cureus, 2020 Feb 03;12(2):e6850.
    PMID: 32181085 DOI: 10.7759/cureus.6850
    Cervical spine injuries are rare occurrences in children, especially the congenital anomalies of the atlas vertebra. Any injury involving the craniovertebral junction such as Jefferson fracture, is a valid cause for alarm due to the complex nature of the craniovertebral junction and the morbidity associated with it. We report the case of a 10-year-old male, who had failure of fusion of anterior arch of atlas due to the failure of formation of the anterior midline synchondrosis, and this mimicked a Jefferson fracture. If it was not for the peculiar absence of any corresponding evidence to suggest spinal injury, we might have mistaken this extremely rare but benign anomaly for a Jefferson fracture and subjected the patient to needless surgical treatment. Hence, it is concluded that keen clinical acumen and clear understanding of the developmental anatomy of these patients may be necessary to adequately manage them.
    Matched MeSH terms: Neck Injuries
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