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Using sosial cognitive theory to understand exercise maintenance in women breast cancer survivors adopting Guolin Qigong

Nadiah Diyana Tan Abdullah, Khor, Poy Hua, Mazanah Muhamad

Movement Health & Exercise, 2013;2(1):47-52.
MyJurnal

The purpose of this study is to explore and understand the exercise maintenance in women with breast cancer survivors adopting Guolin Qigong using the Social Cognitive Theory related constructs. A qualitative approach using in-depth interviews were employed in this study. 22 participants of the Malaysia Guolin Qigong Association from five regions in Peninsular Malaysia were purposely selected to participate in this study. Data was collected through a series of audiotapes during the interview sessions. They were asked on how do they maintain in their Guolin Qigong exercise. Three themes related to the Social Cognitive Theory constructs emerged from the data collected. (i) Personal Factors; (ii) Environmental Factors and (iii) Tailored Program. The belief in Guolin Qigong or in an exercise program is crucial in helping one to maintain with the exercise program and this findings is consistent with literature that those responded favourably to an exercise will have greater positive attitudes to exercise maintenance. To keep these women maintain the exercise it is important that these women have friends who understand them better to share their experiences related to their disease. It has been suggested that connecting to other survivors contributes to the survivors' positive well-being and to deal with their everyday living. Lastly, the type of exercise should be tailored to the physical condition of these women to keep them sustain the exercise. This theory can be used by the health practitioners to develop more effective interventions for increasing exercise maintenance in sedentary cancer survivors by taking into special attention personal factors particularly one's beliefs and inner motivation. Having to embark and engage into an exercise program of their preferred choice will help one to maintain an exercise program.

Matched MeSH terms: Attention
Fulltext Use of Chinese herbal medicine and health-related quality of life among cancer patients in Johor, Malaysia

Loke, Mi Mi, Chong, Kah Hui, Noor Salihah Zakaria, Hayati Mohd Yusof

Malays J Nutr, 2017;23(2):227-238.
MyJurnal

Introduction: Chinese Herbal Medicine (CHM) is becoming increasingly popular among cancer patients worldwide. While health-related quality of life (HRQoL) in relation to cancer outcomes has attracted global attention, there are few studies on CHM use and HRQoL among cancer patients in Malaysia. This study attempted to determine the association between use of CHM, including the types, reasons, and beliefs, and HRQoL among Malaysian cancer patients.
Methods: A cross-sectional study was conducted among 120 cancer patients (60 male and 60 female) recruited from government oncology clinics in Johor state. A purposive non-probability sampling was applied to recruit respondents.
Results: Use of CHM was reported by about half of the patients (49.2%). Common types of CHM used included Chinese herbal extracts (27.5%), Sabah snake grass (12.2%), and ginger (11.5%). The median score for overall belief in CHM significantly differed between
CHM users (71.7%) and non-users (65.0%) (p<0.001). The HRQoL was generally reported as ‘good’ with high scores for overall functioning scales and low scores for symptom scales. However, no significant difference in HRQoL between CHM users and non-users was noted. ‘Social Functioning’ scores between both groups showed a significant difference (p < 0.001) with respect to sex, with females scoring higher than males. No significant association was noted between CHM use and socio-demographic characteristics except for sex.
Conclusion: There is a high prevalence of self-prescription of CHM among the cancer patients studied. Nonetheless use of CHM did not show any significant difference in terms of quality of life among CHM users.
Study site: Oncology clinics, Hospital Sultan Ismail (Johor Bahru) and Hospital Sultanah Nora Ismail (Batu Pahat), Johor, Malaysia

Matched MeSH terms: Attention
Urogenital Vascular Anomalies with Bilateral Kinking of Ureter: A Case Report

Tadipi S, Sadashiv R, Muralidharan S, Pimid M

Malays J Med Sci, 2015 Nov;22(6):67-70.
PMID: 28223889

Variations in the urogenital vascular anomalies in the abdomen are very common. However, they warrant attention due to their importance in operative, diagnostic, and endovascular procedures. During routine dissection of abdomen in a male cadaver, unique urogenital vascular anomalies were observed. On the right side, the right renal artery was found to be originated from the abdominal aorta at the level of L2 and divided into five branches; the right testicular artery and inferior suprarenal artery originated from the lower branch. We also observed, accessory renal artery arising from abdominal aorta at the level of L3 and double renal veins on right side. On the left side, we found left renal artery originating from the abdominal aorta at the level of L2 and divided into two branches. Double testicular (medial and lateral) arteries were also observed. In addition to these vascular variations, bilateral kinking of ureter at the pelviureteric junction was also observed. Although the variations in the origin of urogenital vessels in the abdomen are common, deeper understanding of the urogenital vascular variations and their relations to adjacent structures is significant during surgical and radiological procedures.

Matched MeSH terms: Attention
Fulltext Unveiling the Hurdles in Cultivating Humanistic Physicians in the Clinical Setting: An Exploratory Study

Mustika R, Soemantri D

Malays J Med Sci, 2020 May;27(3):117-124.
PMID: 32684812 DOI: 10.21315/mjms2020.27.3.12

Background: The importance of cultivating a humanistic physician has gained attention in medical education. Humanistic values are established in early education and medical schools should provide a suitable environment to nurture and grow these values into professional identity. The clinical setting has a significant impact due to its direct involvement of students in real-life situations.
Objectives: The present study aims to explore the hurdles in cultivating humanistic physicians in the clinical setting.
Methods: We conducted a qualitative study involving medical students in the clinical phase, as well as residents, clinical teachers, and module administrators in the clinical setting under study.
Results: Respondents from different groups of stakeholders shared the same definition for 'humanistic physician': a physician who provides patient-centred care while demonstrating empathy, respect, compassion, integrity, knowledge, competence and a collaborative spirit. Despite changes in the healthcare system and technological advancements, humanistic physicians are still needed.
Conclusion: Cultivating humanistic physicians is a complex process, requiring various methods and assessments. Role models play a significant role in this process, which included not only clinical teachers but also peers. Feedback from peers was perceived as an important factor. The key hurdles identified were negative role models, and a less humanistic learning environment and the students' personal backgrounds.

Matched MeSH terms: Attention
Unsteady free convection flow between two vertical parallel plates with newtonian heating

Fasihah Zulkiflee, Ahmad Qushairi Mohamad, Sharidan Shafie, Arshad Khan

MATEMATIKA, 2019;35(2):117-127.
MyJurnal

Free convection flow in a boundary layer region is a motion that results from the interaction of gravity with density differences within a fluid. These differences occur due to temperature or concentration gradients or due to their composition. Studies per- taining free convection flows of incompressible viscous fluids have received much attention in recent years both theoretically (exact or approximate solutions) and experimentally. The situation where the heat be transported to the convective fluid via a bounding sur- face having finite heat capacity is known as Newtonian heating (or conjugate convective flows). In this paper, the unsteady free convection flow of an incompressible viscous fluid between two parallel plates with Newtonian heating is studied. Appropriate non- dimensional variables are used to reduce the dimensional governing equations along with imposed initial and boundary conditions into dimensionless forms. The exact solutions for velocity and temperature are obtained using the Laplace transform technique. The corresponding expressions for skin friction and Nusselt number are also calculated. The graphical results are displayed to illustrate the influence of various embedded parameters such as Newtonian heating parameter and Grashof number. The results show that the effect of Newtonian heating parameter increases the Nusselt number but reduces the skin friction.

Matched MeSH terms: Attention
Fulltext Undiagnosed chicken meat aspiration as a cause of difficult-to-ventilate in a boy with traumatic brain injury

Mohd Ariff NA, Mazlan MZ, Mat Hassan ME, Seevaunnamtum PA, Wan Muhd Shukeri WF, Nik Mohamad NA, et al.

Respir Med Case Rep, 2018;23:93-95.
PMID: 29387523 DOI: 10.1016/j.rmcr.2018.01.001

Introduction: Bronchoscopy is a commonly used procedure in the context of aspiration in the Intensive Care Unit setting. Despite its ability to remove mucus plug and undigested gastric contents, aspiration of gastric content into the trachea is one of the most feared complications among anesthesiologist.
Discussion: The scenario is made worst if the aspiration causes acute hypoxemic respiratory failure immediately post intubation. However, in the event of desaturation, the quick decision to proceed with bronchoscopy is a challenging task to the anesthesiologist without knowing the causes.
Case presentation: We present a case of a 12-year-old boy who had a difficult-to-ventilate scenario post transferring and immediately connected to ventilator in operation theatre (OT) from portable ventilator from the emergency department. She was successfully managed by bronchoscopy.
Conclusion: Special attention should be given to the difficult-to-ventilate scenario post intubation of traumatic brain injury patient prior to operation. Prompt diagnosis and bronchoscope-assisted removal of foreign body was found to be a successful to reduce morbidity and mortality.

Matched MeSH terms: Attention
Fulltext Understanding Myths in Pregnancy and Childbirth and the Potential Adverse Consequences: A Systematic Review

Ahmad N, Nor SFS, Daud F

Malays J Med Sci, 2019 Jul;26(4):17-27.
PMID: 31496890 MyJurnal DOI: 10.21315/mjms2019.26.4.3

The trend of choosing natural birth at home without proper supervision is gaining more attention and popularity in Malaysia. This is partly due to wrong beliefs of modern medical care. It prompts the need to explore further into other myths and wrong beliefs present in communities around the world surrounding pregnancy and childbirth that may lead to harmful consequences. A total of 25 literatures were selected and reviewed. The most reported wrong belief is the eating behaviour such as avoiding certain nutritious fruits besides eating saffron to produce fairer skinned babies which in fact contains high doses of saffron that may lead to miscarriage. The most worrying myth however, is that unregulated birth attendants such as doulas have the necessary knowledge and skills to manage complications in labour which may well end up in perinatal or even maternal death. Other myths suggested that modern medical care such as vaginal examinations and baby's heart monitoring in labour as unnecessary. A well-enforced health education programme by well-trained healthcare personnel besides sufficient number of antenatal care visits are needed to overcome these myths, wrong beliefs and practices. In conclusion, potential harmful beliefs and practices in pregnancy and childbirth are still abound in today's communities, not just in least developed and developing countries but also in developed countries. Women and children are two very vulnerable groups, therefore debunking myths and eliminating harmful practices should be one of a healthcare provider priority especially those in the primary care settings as they are the closest to the community.

Matched MeSH terms: Attention
Tumor-responsive dynamic nanoassemblies for targeted imaging, therapy and microenvironment manipulation

Low LE, Wu J, Lee J, Tey BT, Goh BH, Gao J, et al.

J Control Release, 2020 Aug 10;324:69-103.
PMID: 32423874 DOI: 10.1016/j.jconrel.2020.05.014

The recent designs of dynamic nanoassemblies exploiting the tumor-targeting properties have received increasing attention for tumor imaging and therapy due to their tumor-specific delivery and enhanced antitumor efficacy. However, these designs are mainly focused on the macroscopic tumor therapeutic effect, while the nano-bio interactions in the tumor microenvironment (TME) remain poorly understood. This review aims to provide an overview of the development of tumor-responsive nanoassemblies towards the imaging, therapy and TME modulation in the tumor site. The tumor biology leading to TME formation and the potential TME properties for the practicable design of tumor-targeting nanoassemblies has been outlined. Furthermore, the various approaches for TME modification and the realization via dynamic nanoassemblies for enhanced tumor therapy were reviewed. Lastly, the prospects of these methods were briefly discussed. These strategies may inspire the development of new combinational cancer therapeutics.

Matched MeSH terms: Attention
Fulltext Trends of prevalence of anaemia among adolescents in a middle-income country: a cohort study

Vanitha Krishnan, Hazreen Abdul Majid, Rafdzah Ahmad Zaki, Muhammad Yazid Jalaludin

Malaysian Journal of Medicine and Health Sciences, 2019;15(104):105-105.
MyJurnal

Introduction: Anaemia is a significant public health problem among adolescents globally but there is limited data in many countries, including Malaysia. This study aims to investigate the 5-years incidence of anemia among Malaysian adolescents by gender, ethnicity, locality of schools, Body Mass Index, stature and diet intake. Methods: A secondary analysis of existing data from MyHeART study was conducted within a closed cohort of 528 adolescents (aged 13 years) attended 15 public secondary schools from Kuala Lumpur, Selangor and Perak. The adolescents who were followed up at 15 and 17 years old had completed haemoglobin assessment, anthropometric measurements and -days diet history. The data was cleaned and missingness was handled accordingly with multiple imputation. SPSS Software version 21 was used to analyse the data, with Generalised Estimating Equation (GEE) showing the effect of time on the trajectory of prevalence of anaemia over the 5 years. Results: The prevalence or incidence? of anaemia in 2012, 2014 and 2016 was 7.9% (95%CI: 5.0-12.3), 13.9% (95%CI: 10.0-19.0) and 15.8% (95%CI:11.3-21.7). In females, anaemia increased from 11.1% (95%CI:6.7-18.7) to 15.7% (11.4-21.3) and 23.1%(95%CI: 16.8-31.0); the change was significant from 13 to 15 years old. Similar trend was noticed in those who are stunted, overweight/obese, in both urban/rural schools and didn’t meet their daily recommended nutrient intake for total calorie, protein and iron. Conclusion: Anaemia is increasing in trend among the adolescents over the years and deems attention from the relevant stakeholders to create a robust anemia prevention program.

Matched MeSH terms: Attention
Fulltext Treatment of river water of Sg. Pusu by using magnesium oxide (MGO) coated with chitosan

Nik Nur Syafika Pahri, Nur Huda Syazwani Jafri, Husna Ahmad Tajuddin, Yusilawati Ahmad Nor

Biological and Natural Resources Engineering Journal, 2019;2(1):10-25.
MyJurnal

Effective treatment of wastewater is crucial in order to achieve a sustainable development. For instance, highly efficient treatment processes with low capital requirements are the major prerequisite for implementation of the advanced wastewater treatment operations. Among various available treatment methods, the application of coagulation-flocculation process by using natural coagulant; chitosan has vast advantages such as low operating cost, environmental friendly and highly effective in the wastewater treatment operations. The application of nanotechnology in numerous treatment techniques are considered as the most significant advances in water and wastewater treatment practices. The utilization of magnesium oxide (MgO) as nano-adsorbent has recently gained attention as a potential treatment method in water remediation particularly for treating effluents with high amount of organic dyes and heavy metals due to its high treatment efficiency, low cost, versatility and environment compatibility. The purpose of this study was to determine the effectiveness of coagulation-flocculation process when using novel coagulant in which MgO coated with chitosan by investigating the percentage removal of several significant parameters which were turbidity, chemical oxygen demand (COD) and suspended solid. The removal efficiencies were determined throughout a series of experiments carried out using a standard jar test procedure in which three different coagulants; chitosan, MgO coated with chitosan and MgO were tested on water samples taken from Sg. Pusu. In addition, a set of experiments was designed using response surface methodology (RSM) in order to optimize adsorption of chitosan into MgO. The experiments were conducted at various concentrations of chitosan (10-30 mg/ml) and selected MgO dosage ranges (10-30 mg). From the obtained results, it was found that chitosan-MgO coagulant has good removal efficiencies of turbidity, chemical oxygen demand (COD) and suspended solids at 92%, 91%, and 98% respectively from the optimization of adsorption of chitosan-MgO. The MgO coated with chitosan is the best coagulant in this study compared to chitosan and MgO alone because of the ability of treating the river water with up to 90 % removal for all the main parameters. The results showed that coagulation-flocculation is effective as a treatment for treating river water.

Matched MeSH terms: Attention
Fulltext Timing of Surgery and Surgical Strategies in Symptomatic Brainstem Cavernomas: Review of the Literature

Rajagopal N, Kawase T, Mohammad AA, Seng LB, Yamada Y, Kato Y

Asian J Neurosurg, 2019 4 3;14(1):15-27.
PMID: 30937003 DOI: 10.4103/ajns.AJNS_158_18

Brainstem cavernomas (BSCs) are angiographically occult, benign low flow vascular malformations that pose a significant surgical challenge due to their eloquent location. The present study includes an extensive review of the literature and three illustrative cases of BSC with emphasis on the timing of surgery: surgical approaches, usage of intraoperative monitoring, and complication avoidance. A systematic search was performed using the PubMed database was from January 1, 1999, to June 2018. The relevant articles were reviewed with particular attention to hemorrhage rates, timing of surgery, indications for surgery, surgical approaches, and outcome. Along with this, a retrospective analysis of three cases of symptomatic BSC, who were operated for the same, during the year 2018 in our institute was conducted. All the three patients presented with at least 1 episode of hemorrhage before surgery. Of these, one patient was operated immediately due to altered sensorium whereas the other two were operated after at least 4 weeks of the hemorrhagic episode. The patients who were operated in the subacute phase of bleed were seen to have liquefaction of hematoma, thus providing a good surgical demarcation and thereby reduced surgery-related trauma to the surrounding eloquent structures. Two patients improved neurologically during the immediate postoperative period, whereas one had transient worsening of neurological deficits during the immediate postoperative period in the form of additional cranial nerve palsies which completely improved on follow-up after 2 months. Radical resection is recommended in all patients with symptomatic BSCs. Surgery should be considered after the first or the second episode of hemorrhage as multiple rebleeds can cause exacerbation of deficits and sometimes mortality as well. Considering surgical timing, anywhere between 4 and 6 weeks or the subacute phase of the hemorrhage is considered appropriate. The aims of surgical intervention must be to improve preoperative function, minimize surgical morbidity and to reduce hemorrhagic rates. In spite of the significant surgical morbidity associated with BSCs, appropriate patient selection, meticulous surgical planning with adjuncts such as intraoperative monitoring and neuronavigation will go a long way in avoidance of major postoperative complications.

Matched MeSH terms: Attention
Time sharing in working memory processing

Barrouillet P, Camos V, Minamoto T, Nishiyama S, Chooi WT, Morita A, et al.

J Exp Psychol Learn Mem Cogn, 2023 Oct;49(10):1539-1556.
PMID: 37307321 DOI: 10.1037/xlm0001261

Although working memory (WM) is usually defined as a cognitive system coordinating processing and storage in the short term, in most WM models, memory aspects have been developed more fully than processing systems, and many studies of WM tasks have tended to focus on memory performance. The present study investigated WM functioning without focusing exclusively on short-term memory performance by presenting participants with an n-back task on letters, n varying from 0 to 2, each letter being followed by a tone discrimination task involving from one to three tones. Predictions regarding the reciprocal effects of these tasks on each other were motivated by the time-based resource-sharing (TBRS) theoretical framework for WM that assumes the temporal sharing of attention between processing and memory. Although, as predicted, increasing the n value had a detrimental effect on tone discrimination in terms of accuracy and response times, and increasing the number of tones disrupted speed and accuracy on n-back performance, the overall pattern of results did not perfectly fit the TBRS predictions. Nonetheless, the main alternative models of WM do not seem to offer a complete account. The present findings point toward the need to use a larger range of tasks and situations in designing and testing models of WM. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Matched MeSH terms: Attention/physiology
Time course of inhibition of return in a spatial cueing paradigm with distractors

Eng V, Lim A, Janssen SMJ, Satel J

Acta Psychol (Amst), 2018 Feb;183:51-57.
PMID: 29328938 DOI: 10.1016/j.actpsy.2017.12.011

Studies of endogenous and exogenous attentional orienting in spatial cueing paradigms have been used to investigate inhibition of return, a behavioral phenomenon characterized by delayed reaction time in response to recently attended locations. When eye movements are suppressed, attention is covertly oriented to central or peripheral stimuli. Overt orienting, on the other hand, requires explicit eye movements to the stimuli. The present study examined the time course of slowed reaction times to previously attended locations when distractors are introduced into overt and covert orienting tasks. In a series of experiments, manual responses were required to targets following central and peripheral cues at three different cue-target intervals, with and without activated oculomotor systems. The results demonstrate that, when eye movements are suppressed, behavioral inhibition is reduced or delayed in magnitude by the presence of a distractor relative to conditions without distractors. However, the time course of behavioral inhibition when eye movements are required remains similar with or without distractors.

Matched MeSH terms: Attention/physiology
Fulltext Three-dimensional cell culture at the frontiers of in vitro cancer research: present perspectives

Lee, Soo Leng, Zainal Ariff Abdul Rahman, Tsujigiwa, Hidetsugu, Takabatake, Kiyofumi, Nakano, Keisuke, Chai, Wen Lin, et al.

Ann Dent, 2016;23(1):13-22.
MyJurnal

In recent years, three-dimensional (3D) in vitro cell culture models have earned great attention, especially in the field of human cancer disease modelling research as they provide a promising alternative towards the conventional two-dimensional (2D) monolayer culture of cells with improved tissue organization. In 2D cell culture systems, the complexity of cells on a planar surface does not accurately reflects the in vivo cellular microenvironment. Cells propagated in 3D cell culture model, on the other hand, exhibit physiologically relevant cell-to-cell interactions and cell-to-extracellular matrix (ECM) interactions, important in maintaining a normal homeostasis and specificity of tissues. This review gives an overview on 2D models and their limitations, followed by 3D cell culture models, their advantages, drawbacks and challenges in present perspectives. The review also highlights the dissimilarities of 2D and 3D models and the applicability of 3D models in current cancer research

Matched MeSH terms: Attention
Thinking, learning and learning disabilities

Sinniah, Davendralingam

Malaysian Journal of Child Health, 1997;9(2):160-165.
MyJurnal

Thinking is something that we do all through our lives - an activity thcit possibly antedates our very birth itself Yet our children and we are not told about thinking or taught about the thinking process that dominates our lives, possibly, because of our own limited under-standing. Consequently, children are told to be logical and are discouraged from thinking differently, because it is the only type of think-ing we know and can understand. Methods of assessing their performance based on logical thinking underestimate their true potentials. The creative potentials of these children, 40% of who are right-brained need to be harnessed by approaches to learning that utilize methods of teaching and assessment, appropriate for their style of thinking. Another group of children, who need special attention, are those with learning disabilities that have been ignored, but can be corrected with appropriate programmes that provide a comprehensive approach to regular and special education.

Matched MeSH terms: Attention
Fulltext Thickness Optimization of Thin-Film Tandem Organic Solar Cell

Bangash KA, Kazmi SAA, Farooq W, Ayub S, Musarat MA, Alaloul WS, et al.

Micromachines (Basel), 2021 May 05;12(5).
PMID: 34062988 DOI: 10.3390/mi12050518

The polymer solar cells also known as organic solar cells (OSCs) have drawn attention due to their cynosure in industrial manufacturing because of their promising properties such as low weight, highly flexible, and low-cost production. However, low η restricts the utilization of OSCs for potential applications such as low-cost energy harvesting devices. In this paper, OSCs structure based on a triple-junction tandem scheme is reported with three different absorber materials to enhance the absorption of photons which in turn improves the η, as well as its correlating performance parameters. The investigated structure gives the higher value of η = 14.33% with Jsc = 16.87 (mA/m2), Voc = 1.0 (V), and FF = 84.97% by utilizing a stack of three different absorber layers with different band energies. The proposed structure was tested under 1.5 (AM) with 1 sun (W/m2). The impact of the top, middle, and bottom subcells' thickness on η was analyzed with a terse to find the optimum thickness for three subcells to extract high η. The optimized structure was then tested with different electrode combinations, and the highest η was recorded with FTO/Ag. Moreover, the effect of upsurge temperature was also demonstrated on the investigated schematic, and it was observed that the upsurge temperature affects the photovoltaic (PV) parameters of the optimized cell and η decreases from 14.33% to 11.40% when the temperature of the device rises from 300 to 400 K.

Matched MeSH terms: Attention
Thermoseparating aqueous two-phase systems: Recent trends and mechanisms

Leong YK, Lan JC, Loh HS, Ling TC, Ooi CW, Show PL

J Sep Sci, 2016 Feb;39(4):640-7.
PMID: 26447739 DOI: 10.1002/jssc.201500667

Having the benefits of being environmentally friendly, providing a mild environment for bioseparation, and scalability, aqueous two-phase systems (ATPSs) have increasingly caught the attention of industry and researchers for their application in the isolation and recovery of bioproducts. The limitations of conventional ATPSs give rise to the development of temperature-induced ATPSs that have distinctive thermoseparating properties and easy recyclability. This review starts with a brief introduction to thermoseparating ATPSs, including its history, unique characteristics and advantages, and lastly, key factors that influence partitioning. The underlying mechanism of temperature-induced ATPSs is covered together with a summary of recent applications. Thermoseparating ATPSs have been proven as a solution to the demand for economically favorable and environmentally friendly industrial-scale bioextraction and purification techniques.

Matched MeSH terms: Attention
Fulltext Therapeutic effects of conditioned - DPBS from amniotic stem cells on lactating cow mastitis

Ting WJ, Shaw SW, Hii LY, Lin TY, Chang SC, Liu KY, et al.

Taiwan J Obstet Gynecol, 2020 Jul;59(4):520-526.
PMID: 32653123 DOI: 10.1016/j.tjog.2020.05.009

OBJECTIVE: Bovine mastitis results in economic loss due to decrease in milk production. Antibiotic ointments are commonly used for treating. However, residue and anti-microbial resistance warranted attention progressively. Fortunately, stem cell anti-inflammatory properties and paracrine expression of cytokines accelerates wound healing and suppresses inflammatory reactions in mastitis. The objective of this study is to use the conditioned-Dulbecco's pluripotent stem cells (DPBS) from amniotic membrane stem cells (AMSCs) in treating bovine mastitis.
MATERIALS AND METHODS: The cows with mastitis were divided into two groups. In antibiotic control group, the cows were given tetraneomycin ointment. In conditioned-DPBS of AMSCs treatment group, amniotic membrane was collected for AMSCs after delivery. With expression of surface antigen and potential of tri-linage differentiation, AMSCs were injected into mammary glands. Then, milk was sampled every three days to monitor the effect of both treatments. The quality of milk was measured with pH, titratable acidity, free calcium ions and somatic cell count.
RESULTS: Our results demonstrated the Bovine AMSCs expressed CD44, low levels of CD4 and no CD105. Bovine AMSCs demonstrated the differentiation capability in the tri-cell lineages. Mastitis treatment with conditioned-DPBS from AMSCs (experimental group) and conventional antibiotics (control group) showed insignificant difference in pH value and titratable acidity. The level of ionic calcium concentration in the conditioned-DPBS group decreased from 3rd day to 12th day, while the level in the antibiotic group decreased from 0 day to 12th day. The somatic cell number was similar in both groups, which meet the standard of Taiwan milk collection.
CONCLUSION: In conclusion, conditioned-DPBS from bovine AMSCs has the therapeutic potential to treat bovine mastitis and may replace antibiotics therapy in the future.

Matched MeSH terms: Attention
Fulltext Theoretical analysis of numerical integration rule for nonlinear goursat problem

Deraman, R.F., Mahayadin, M., Mohd Ruslan, S.Z., Othman, N.I., Nasir, M.A.S.

Journal of Advanced Research in Applied Sciences and Engineering Technology, 2016;5(1):1-6.
MyJurnal

Many nonlinear problems that arise in various science and engineering fields can be
modelled by the Goursat partial differential equations. Modelling these non-linear
problems using the Goursat partial differential equations has not received much
attention especially the theoretical aspect . The proposed scheme of solution is
supported by examining a nonlinear Goursat problem. The verification of the
theoretical results from several series of numerical experiments are discussed. Results
obtained from Taylor series expansion show that the proposed new scheme is
consistent. By using the von Neumann analysis and essence of stability, the proposed
new scheme is found to be unconditionally stable. In addition, the trend of the
numerical results shows that the new scheme is also convergent.

Matched MeSH terms: Attention
Fulltext Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds

Zainal Baharum, Abdah Md Akim, Roslida Abdul Hamid, Taufiq Yap Yun Hin, Rosmin Kasran

Trop Life Sci Res, 2016;27(1):21-42.
MyJurnal

Plants have been a good source of therapeutic agents for thousands of years;
an impressive number of modern drugs used for treating human diseases are derived from
natural sources. The Theobroma cacao tree, or cocoa, has recently garnered increasing
attention and become the subject of research due to its antioxidant properties, which are
related to potential anti-cancer effects. In the past few years, identifying and developing
active compounds or extracts from the cocoa bean that might exert anti-cancer effects
have become an important area of health- and biomedicine-related research. This review
provides an updated overview of T. cacao in terms of its potential anti-cancer compounds
and their extraction, in vitro bioassay, purification, and identification. This article also
discusses the advantages and disadvantages of the techniques described and reviews the
processes for future perspectives of analytical methods from the viewpoint of anti-cancer
compound discovery.

Matched MeSH terms: Attention

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