Displaying publications 21 - 40 of 66 in total

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  1. Berhanuddin Muhamad Asyraf, Tong, Wah Lim
    Malaysian Dental Journal, 2016;2016(2):0-0.
    MyJurnal
    In nowadays world, aesthetic dentistry has becoming a trend with the improvement of dental technology and materials. Composite resin becomes the material of choice as it offers good aesthetics, longevity and allow for minimally intervention approach. There are various ways of composite restorative techniques recommended to make out the best restorative outcome. Direct restorative technique promise acceptable cost, appointment time and color matching but it is a challenge for the clinician especially for extensive cavities. Indirect technique is good for extended cavity and providing less operator error, however, it requires multiple appointments, higher cost and laboratory involvement. Computer-aided design/ computer-aided manufacturing (CAD/CAM) technology might reduce the number of appointments, however, it will cause more financial burden to the patient and the clinician. Therefore, semi-direct technique was introduced, it combines the benefits of direct and indirect technique and this technique can be done without the use of any advanced technology and give out a good treatment outcome.
    Matched MeSH terms: Computer-Aided Design
  2. Chan YJ, Chong MF, Law CL
    Bioresour Technol, 2012 Dec;125:145-57.
    PMID: 23026327 DOI: 10.1016/j.biortech.2012.08.118
    Thermophilic treatment of palm oil mill effluent (POME) was studied in a novel integrated anaerobic-aerobic bioreactor (IAAB). The IAAB was subjected to a program of steady-state operation over a range of organic loading rate (OLR)s, up to 30 g COD/L day in order to evaluate its treatment capacity. The thermophilic IAAB achieved high chemical oxygen demand (COD), biochemical oxygen demand (BOD) and total suspended solids (TSS) removal efficiencies of more than 99% for OLR up to 18.5 g COD/L day. High methane yield of 0.32 LCH(4) (STP)/g COD(removed) with compliance of the final treated effluent to the discharge limit were achieved. This is higher than that of the mesophilic system due to the higher maximum specific growth rate (μ(max)) of the thermophilic microorganisms. Besides, coupling the model of Grau second order model (anaerobic system) with the model of Monod (aerobic system) will completely define the IAAB system.
    Matched MeSH terms: Computer-Aided Design
  3. Chen J, Ahmad R, Suenaga H, Li W, Sasaki K, Swain M, et al.
    PLoS One, 2015;10(7):e0132552.
    PMID: 26161878 DOI: 10.1371/journal.pone.0132552
    With ever-growing aging population and demand for denture treatments, pressure-induced mucosa lesion and residual ridge resorption remain main sources of clinical complications. Conventional denture design and fabrication are challenged for its labor and experience intensity, urgently necessitating an automatic procedure. This study aims to develop a fully automatic procedure enabling shape optimization and additive manufacturing of removable partial dentures (RPD), to maximize the uniformity of contact pressure distribution on the mucosa, thereby reducing associated clinical complications. A 3D heterogeneous finite element (FE) model was constructed from CT scan, and the critical tissue of mucosa was modeled as a hyperelastic material from in vivo clinical data. A contact shape optimization algorithm was developed based on the bi-directional evolutionary structural optimization (BESO) technique. Both initial and optimized dentures were prototyped by 3D printing technology and evaluated with in vitro tests. Through the optimization, the peak contact pressure was reduced by 70%, and the uniformity was improved by 63%. In vitro tests verified the effectiveness of this procedure, and the hydrostatic pressure induced in the mucosa is well below clinical pressure-pain thresholds (PPT), potentially lessening risk of residual ridge resorption. This proposed computational optimization and additive fabrication procedure provides a novel method for fast denture design and adjustment at low cost, with quantitative guidelines and computer aided design and manufacturing (CAD/CAM) for a specific patient. The integration of digitalized modeling, computational optimization, and free-form fabrication enables more efficient clinical adaptation. The customized optimal denture design is expected to minimize pain/discomfort and potentially reduce long-term residual ridge resorption.
    Matched MeSH terms: Computer-Aided Design*
  4. Cheung JPY, Cheung PWH, Shigematsu H, Takahashi S, Kwan MK, Chan CYW, et al.
    J Orthop Surg (Hong Kong), 2020 6 13;28(2):2309499020930291.
    PMID: 32529908 DOI: 10.1177/2309499020930291
    PURPOSE: To determine consensus among Asia-Pacific surgeons regarding nonoperative management for adolescent idiopathic scoliosis (AIS).

    METHODS: An online REDCap questionnaire was circulated to surgeons in the Asia-Pacific region during the period of July 2019 to September 2019 to inquire about various components of nonoperative treatment for AIS. Aspects under study included access to screening, when MRIs were obtained, quality-of-life assessments used, role of scoliosis-specific exercises, bracing criteria, type of brace used, maturity parameters used, brace wear regimen, follow-up criteria, and how braces were weaned. Comparisons were made between middle-high income and low-income countries, and experience with nonoperative treatment.

    RESULTS: A total of 103 responses were collected. About half (52.4%) of the responders had scoliosis screening programs and were particularly situated in middle-high income countries. Up to 34% obtained MRIs for all cases, while most would obtain MRIs for neurological problems. The brace criteria were highly variable and was usually based on menarche status (74.7%), age (59%), and Risser staging (92.8%). Up to 52.4% of surgeons elected to brace patients with large curves before offering surgery. Only 28% of responders utilized CAD-CAM techniques for brace fabrication and most (76.8%) still utilized negative molds. There were no standardized criteria for brace weaning.

    CONCLUSION: There are highly variable practices related to nonoperative treatment for AIS and may be related to availability of resources in certain countries. Relative consensus was achieved for when MRI should be obtained and an acceptable brace compliance should be more than 16 hours a day.

    Matched MeSH terms: Computer-Aided Design
  5. Choong YS, Lee YV, Soong JX, Law CT, Lim YY
    Adv Exp Med Biol, 2017;1053:221-243.
    PMID: 29549642 DOI: 10.1007/978-3-319-72077-7_11
    The use of monoclonal antibody as the next generation protein therapeutics with remarkable success has surged the development of antibody engineering to design molecules for optimizing affinity, better efficacy, greater safety and therapeutic function. Therefore, computational methods have become increasingly important to generate hypotheses, interpret and guide experimental works. In this chapter, we discussed the overall antibody design by computational approches.
    Matched MeSH terms: Computer-Aided Design*
  6. Farook TH, Abdullah JY, Jamayet NB, Alam MK
    J Prosthet Dent, 2021 Feb 15.
    PMID: 33602541 DOI: 10.1016/j.prosdent.2020.07.039
    STATEMENT OF PROBLEM: Computer-aided design (CAD) of maxillofacial prostheses is a hardware-intensive process. The greater the mesh detail is, the more processing power is required from the computer. A reduction in mesh quality has been shown to reduce workload on computers, yet no reference value of reduction is present for intraoral prostheses that can be applied during the design.

    PURPOSE: The purpose of this simulation study was to establish a reference percentage value that can be used to effectively reduce the size and polygons of the 3D mesh without drastically affecting the dimensions of the prosthesis itself.

    MATERIAL AND METHODS: Fifteen different maxillary palatal defects were simulated on a dental cast and scanned to create 3D casts. Digital bulbs were fabricated from the casts. Conventional bulbs for the defects were fabricated, scanned, and compared with the digital bulb to serve as a control. The polygon parameters of digital bulbs were then reduced by different percentages (75%, 50%, 25%, 10%, 5%, and 1% of the original mesh) which created a total of 105 meshes across 7 mesh groups. The reduced mesh files were compared individually with the original design in an open-source point cloud comparison software program. The parameters of comparison used in this study were Hausdorff distance (HD), Dice similarity coefficient (DSC), and volume.

    RESULTS: The reduction in file size was directly proportional to the amount of mesh reduction. There were minute yet insignificant differences in volume (P>.05) across all mesh groups, with significant differences (P

    Matched MeSH terms: Computer-Aided Design
  7. Farook TH, Jamayet NB, Abdullah JY, Asif JA, Rajion ZA, Alam MK
    Comput Biol Med, 2020 03;118:103646.
    PMID: 32174323 DOI: 10.1016/j.compbiomed.2020.103646
    OBJECTIVE: To design and compare the outcome of commercial (CS) and open source (OS) software-based 3D prosthetic templates for rehabilitation of maxillofacial defects using a low powered personal computer setup.

    METHOD: Medical image data for five types of defects were selected, segmented, converted and decimated to 3D polygon models on a personal computer. The models were transferred to a computer aided design (CAD) software which aided in designing the prosthesis according to the virtual models. Two templates were designed for each defect, one by an OS (free) system and one by CS. The parameters for analyses were the virtual volume, Dice similarity coefficient (DSC) and Hausdorff's distance (HD) and were executed by the OS point cloud comparison tool.

    RESULT: There was no significant difference (p > 0.05) between CS and OS when comparing the volume of the template outputs. While HD was within 0.05-4.33 mm, evaluation of the percentage similarity and spatial overlap following the DSC showed an average similarity of 67.7% between the two groups. The highest similarity was with orbito-facial prostheses (88.5%) and the lowest with facial plate prosthetics (28.7%).

    CONCLUSION: Although CS and OS pipelines are capable of producing templates which are aesthetically and volumetrically similar, there are slight comparative discrepancies in the landmark position and spatial overlap. This is dependent on the software, associated commands and experienced decision-making. CAD-based templates can be planned on current personal computers following appropriate decimation.

    Matched MeSH terms: Computer-Aided Design*
  8. Farook TH, Barman A, Abdullah JY, Jamayet NB
    J Prosthodont, 2021 Jun;30(5):420-429.
    PMID: 33200429 DOI: 10.1111/jopr.13286
    PURPOSE: Mesh optimization reduces the texture quality of 3D models in order to reduce storage file size and computational load on a personal computer. This study aims to explore mesh optimization using open source (free) software in the context of prosthodontic application.

    MATERIALS AND METHODS: An auricular prosthesis, a complete denture, and anterior and posterior crowns were constructed using conventional methods and laser scanned to create computerized 3D meshes. The meshes were optimized independently by four computer-aided design software (Meshmixer, Meshlab, Blender, and SculptGL) to 100%, 90%, 75%, 50%, and 25% levels of original file size. Upon optimization, the following parameters were virtually evaluated and compared; mesh vertices, file size, mesh surface area (SA), mesh volume (V), interpoint discrepancies (geometric similarity based on virtual point overlapping), and spatial similarity (volumetric similarity based on shape overlapping). The influence of software and optimization on surface area and volume of each prosthesis was evaluated independently using multiple linear regression.

    RESULTS: There were clear observable differences in vertices, file size, surface area, and volume. The choice of software significantly influenced the overall virtual parameters of auricular prosthesis [SA: F(4,15) = 12.93, R2 = 0.67, p < 0.001. V: F(4,15) = 9.33, R2 = 0.64, p < 0.001] and complete denture [SA: F(4,15) = 10.81, R2 = 0.67, p < 0.001. V: F(4,15) = 3.50, R2 = 0.34, p = 0.030] across optimization levels. Interpoint discrepancies were however limited to <0.1mm and volumetric similarity was >97%.

    CONCLUSION: Open-source mesh optimization of smaller dental prostheses in this study produced minimal loss of geometric and volumetric details. SculptGL models were most influenced by the amount of optimization performed.

    Matched MeSH terms: Computer-Aided Design
  9. Farook TH, Jamayet NB, Asif JA, Din AS, Mahyuddin MN, Alam MK
    Sci Rep, 2021 04 19;11(1):8469.
    PMID: 33875672 DOI: 10.1038/s41598-021-87240-9
    Palatal defects are rehabilitated by fabricating maxillofacial prostheses called obturators. The treatment incorporates taking deviously unpredictable impressions to facsimile the palatal defects into plaster casts for obturator fabrication in the dental laboratory. The casts are then digitally stored using expensive hardware to prevent physical damage or data loss and, when required, future obturators are digitally designed, and 3D printed. Our objective was to construct and validate an economic in-house smartphone-integrated stereophotogrammetry (SPINS) 3D scanner and to evaluate its accuracy in designing prosthetics using open source/free (OS/F) digital pipeline. Palatal defect models were scanned using SPINS and its accuracy was compared against the standard laser scanner for virtual area and volumetric parameters. SPINS derived 3D models were then used to design obturators by using (OS/F) software. The resultant obturators were virtually compared against standard medical software designs. There were no significant differences in any of the virtual parameters when evaluating the accuracy of both SPINS, as well as OS/F derived obturators. However, limitations in the design process resulted in minimal dissimilarities. With further improvements, SPINS based prosthetic rehabilitation could create a viable, low cost method for rural and developing health services to embrace maxillofacial record keeping and digitised prosthetic rehabilitation.
    Matched MeSH terms: Computer-Aided Design
  10. Farook TH, Rashid F, Jamayet NB, Abdullah JY, Dudley J, Khursheed Alam M
    J Prosthet Dent, 2022 Oct;128(4):830-836.
    PMID: 33642077 DOI: 10.1016/j.prosdent.2020.12.041
    STATEMENT OF PROBLEM: The anatomic complexity of the ear challenges conventional maxillofacial prosthetic rehabilitation. The introduction of specialized scanning hardware integrated into computer-aided design and computer-aided manufacturing (CAD-CAM) workflows has mitigated these challenges. Currently, the scanning hardware required for digital data acquisition is expensive and not readily available for prosthodontists in developing regions.

    PURPOSE: The purpose of this virtual analysis study was to compare the accuracy and precision of 3-dimensional (3D) ear models generated by scanning gypsum casts with a smartphone camera and a desktop laser scanner.

    MATERIAL AND METHODS: Six ear casts were fabricated from green dental gypsum and scanned with a laser scanner. The resultant 3D models were exported as standard tessellation language (STL) files. A stereophotogrammetry system was fabricated by using a motorized turntable and an automated microcontroller photograph capturing interface. A total of 48 images were captured from 2 angles on the arc (20 degrees and 40 degrees from the base of the turntable) with an image overlap of 15 degrees, controlled by a stepper motor. Ear 1 was placed on the turntable and captured 5 times with smartphone 1 and tested for precision. Then, ears 1 to 6 were scanned once with a laser scanner and with smartphones 1 and 2. The images were converted into 3D casts and compared for accuracy against their laser scanned counterparts for surface area, volume, interpoint mismatches, and spatial overlap. Acceptability thresholds were set at <0.5 mm for interpoint mismatches and >0.70 for spatial overlap.

    RESULTS: The test for smartphone precision in comparison with that of the laser scanner showed a difference in surface area of 774.22 ±295.27 mm2 (6.9% less area) and in volume of 4228.60 ±2276.89 mm3 (13.4% more volume). Both acceptability thresholds were also met. The test for accuracy among smartphones 1, 2, and the laser scanner showed no statistically significant differences (P>.05) in all 4 parameters among the groups while also meeting both acceptability thresholds.

    CONCLUSIONS: Smartphone cameras used to capture 48 overlapping gypsum cast ear images in a controlled environment generated 3D models parametrically similar to those produced by standard laser scanners.

    Matched MeSH terms: Computer-Aided Design
  11. Farook TH, Ahmed S, Jamayet NB, Rashid F, Barman A, Sidhu P, et al.
    Sci Rep, 2023 Jan 28;13(1):1561.
    PMID: 36709380 DOI: 10.1038/s41598-023-28442-1
    The current multiphase, invitro study developed and validated a 3-dimensional convolutional neural network (3D-CNN) to generate partial dental crowns (PDC) for use in restorative dentistry. The effectiveness of desktop laser and intraoral scanners in generating data for the purpose of 3D-CNN was first evaluated (phase 1). There were no significant differences in surface area [t-stat(df) = - 0.01 (10), mean difference = - 0.058, P > 0.99] and volume [t-stat(df) = 0.357(10)]. However, the intraoral scans were chosen for phase 2 as they produced a greater level of volumetric details (343.83 ± 43.52 mm3) compared to desktop laser scanning (322.70 ± 40.15 mm3). In phase 2, 120 tooth preparations were digitally synthesized from intraoral scans, and two clinicians designed the respective PDCs using computer-aided design (CAD) workflows on a personal computer setup. Statistical comparison by 3-factor ANOVA demonstrated significant differences in surface area (P 
    Matched MeSH terms: Computer-Aided Design*
  12. Goo CL, Tan KB
    Case Rep Dent, 2017;2017:9373818.
    PMID: 28396807 DOI: 10.1155/2017/9373818
    This report describes the clinical and technical aspects in the oral rehabilitation of an edentulous patient with knife-edge ridge at the mandibular anterior edentulous region, using implant-retained overdentures. The application of computer-aided design and computer-aided manufacturing (CAD/CAM) in the fabrication of the overdenture framework simplifies the laboratory process of the implant prostheses. The Nobel Procera CAD/CAM System was utilised to produce a lightweight titanium overdenture bar with locator attachments. It is proposed that the digital workflow of CAD/CAM milled implant overdenture bar allows us to avoid numerous technical steps and possibility of casting errors involved in the conventional casting of such bars.
    Matched MeSH terms: Computer-Aided Design
  13. Hashim Y, Sidek O
    J Nanosci Nanotechnol, 2013 Jan;13(1):242-9.
    PMID: 23646723
    This study is the first to demonstrate dimensional optimization of nanowire-complementary metal-oxide-semiconductor inverter. Noise margins and inflection voltage of transfer characteristics are used as limiting factors in this optimization. Results indicate that optimization depends on both dimensions ratio and digital voltage level (Vdd). Diameter optimization reveals that when Vdd increases, the optimized value of (Dp/Dn) decreases. Channel length optimization results show that when Vdd increases, the optimized value of Ln decreases and that of (Lp/Ln) increases. Dimension ratio optimization reveals that when Vdd increases, the optimized value of Kp/Kn decreases, and silicon nanowire transistor with suitable dimensions (higher Dp and Ln with lower Lp and Dn) can be fabricated.
    Matched MeSH terms: Computer-Aided Design
  14. Hassan LA, Goo CL
    Dent Mater J, 2021 Sep 30;40(5):1189-1195.
    PMID: 34078778 DOI: 10.4012/dmj.2020-408
    This research aimed to evaluate the effect of cement space on the marginal discrepancy and retention of computer-aided design/computer-aided manufacturing (CAD/CAM) crowns. A total of 30 premolar Frasaco teeth were machined to receive crowns with cement spaces of 70, 90, and 110 μm. The marginal discrepancy measurements were done before and after cementation. Pull-off test was conducted using universal testing machine (UTM). Data was analyzed using two-way mixed ANOVA with post-hoc Bonferroni test and Kruskal-Wallis test. The crowns with cement space of 70 μm showed a significantly higher absolute marginal discrepancy than those with 90 and 110 μm. No significant effect on the crown retention was found. Within the limitations of this study, modifying cement space to 90 μm and 110 μm may improve the marginal adaptation of CAD/CAM crown, whereas adjusting cement space from 70 to 110 μm did not significantly affect the crown retention.
    Matched MeSH terms: Computer-Aided Design
  15. Hollister SJ, Lin CY, Lin CY, Schek RD, Taboas JM, Flanagan CL, et al.
    Med J Malaysia, 2004 May;59 Suppl B:131-2.
    PMID: 15468853
    Matched MeSH terms: Computer-Aided Design*
  16. Ibrahim MD, Amran SNA, Yunos YS, Rahman MRA, Mohtar MZ, Wong LK, et al.
    Appl Bionics Biomech, 2018;2018:7854321.
    PMID: 29853998 DOI: 10.1155/2018/7854321
    The skin of a fast swimming shark reveals riblet structures that help reduce the shark's skin friction drag, enhancing its efficiency and speed while moving in the water. Inspired by the structure of the shark skin denticles, our team has carried out a study as an effort in improving the hydrodynamic design of marine vessels through hull design modification which was inspired by this riblet structure of shark skin denticle. Our study covers on macroscaled design modification. This is an attempt to propose an alternative for a better economical and practical modification to obtain a more optimum cruising characteristics for marine vessels. The models used for this study are constructed using computer-aided design (CAD) software, and computational fluid dynamic (CFD) simulations are then carried out to predict the effectiveness of the hydrodynamic effects of the biomimetic shark skins on those models. Interestingly, the numerical calculated results obtained show that the presence of biomimetic shark skin implemented on the vessels give about 3.75% reduction of drag coefficient as well as reducing up to 3.89% in drag force experienced by the vessels. Theoretically, as force drag can be reduced, it can lead to a more efficient vessel with a better cruising speed. This will give better impact to shipping or marine industries around the world. However, it can be suggested that an experimental procedure is best to be conducted to verify the numerical result that has been obtained for further improvement on this research.
    Matched MeSH terms: Computer-Aided Design
  17. Ishak MI, Kadir MR, Sulaiman E, Kasim NH
    Int J Oral Maxillofac Implants, 2013 May-Jun;28(3):e151-60.
    PMID: 23748334 DOI: 10.11607/jomi.2304
    To compare the extramaxillary approach with the widely used intrasinus approach via finite element method.
    Matched MeSH terms: Computer-Aided Design
  18. Ishak MI, Abdul Kadir MR, Sulaiman E, Abu Kasim NH
    Int J Oral Maxillofac Surg, 2012 Sep;41(9):1077-89.
    PMID: 22575179 DOI: 10.1016/j.ijom.2012.04.010
    The aim of this study was to compare two different types of surgical approaches, intrasinus and extramaxillary, for the placement of zygomatic implants to treat atrophic maxillae. A computational finite element simulation was used to analyze the strength of implant anchorage for both approaches in various occlusal loading locations. Three-dimensional models of the craniofacial structures surrounding a region of interest, soft tissue and framework were developed using computed tomography image datasets. The implants were modelled using computer-aided design software. The bone was assumed to be linear isotropic with a stiffness of 13.4 GPa, and the implants were assumed to be made of titanium with a stiffness of 110 GPa. Masseter forces of 300 N were applied at the zygomatic arch, and occlusal loads of 150 N were applied vertically onto the framework surface at different locations. The intrasinus approach demonstrated more satisfactory results and could be a viable treatment option. The extramaxillary approach could also be recommended as a reasonable treatment option, provided some improvements are made to address the cantilever effects seen with that approach.
    Matched MeSH terms: Computer-Aided Design*
  19. Islam MM, Islam MT, Faruque MR
    ScientificWorldJournal, 2013;2013:378420.
    PMID: 24385878 DOI: 10.1155/2013/378420
    The dual-band operation of a microstrip patch antenna on a Duroid 5870 substrate for Ku- and K-bands is presented. The fabrication of the proposed antenna is performed with slots and a Duroid 5870 dielectric substrate and is excited by a 50 Ω microstrip transmission line. A high-frequency structural simulator (HFSS) is used which is based on the finite element method (FEM) in this research. The measured impedance bandwidth (2 : 1 VSWR) achieved is 1.07 GHz (15.93 GHz-14.86 GHz) on the lower band and 0.94 GHz (20.67-19.73 GHz) on the upper band. A stable omnidirectional radiation pattern is observed in the operating frequency band. The proposed prototype antenna behavior is discussed in terms of the comparisons of the measured and simulated results.
    Matched MeSH terms: Computer-Aided Design*
  20. Islam NN, Hannan MA, Shareef H, Mohamed A, Salam MA
    ScientificWorldJournal, 2014;2014:549094.
    PMID: 24977210 DOI: 10.1155/2014/549094
    Power oscillation damping controller is designed in linearized model with heuristic optimization techniques. Selection of the objective function is very crucial for damping controller design by optimization algorithms. In this research, comparative analysis has been carried out to evaluate the effectiveness of popular objective functions used in power system oscillation damping. Two-stage lead-lag damping controller by means of power system stabilizers is optimized using differential search algorithm for different objective functions. Linearized model simulations are performed to compare the dominant mode's performance and then the nonlinear model is continued to evaluate the damping performance over power system oscillations. All the simulations are conducted in two-area four-machine power system to bring a detailed analysis. Investigated results proved that multiobjective D-shaped function is an effective objective function in terms of moving unstable and lightly damped electromechanical modes into stable region. Thus, D-shape function ultimately improves overall system damping and concurrently enhances power system reliability.
    Matched MeSH terms: Computer-Aided Design*
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