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Fulltext Distribution and prevalence of chloramphenicol-resistance gene in Escherichia coli isolated from aquaculture and other environment

Ng, K.H., Samuel, L., Kathleen, M.M., Leong, S.S., Felecia, C.

International Food Research Journal, 2014;21(4):1321-1325.
MyJurnal

In Malaysia, the aquaculture industry, particularly the production of freshwater aquaculture fish, is growing rapidly. Nevertheless, the illegal use of banned antimicrobial agents such as chloramphenicol in aquaculture has become a major concern in relation to the safety of consumers and also the development of drug-resistant strains in bacteria. Driven by those factors, the main intention of this study was to determine the prevalence and types of chloramphenicol resistance genes in E. coli isolated from aquaculture and other environmental waters. The respective chloramphenicol-resistance genes in the isolates were detected by multiplex PCR with four sense primers C-1, C-2, C-3, C-4 and one antisense primer C-R for targeting cat I, cat II, cat III and cat IV genes, respectively. Out of 27 E. coli isolated, 19 were resistant to chloramphenicol. Cat I, cat II, cat III and cat IV genes were detected in 19, 13, 10, and 6 of the E. coli isolates, respectively. The results of this study revealed that chloramphenicol-resistance E. coli is present in aquaculture and environmental waters, in the study area. This finding suggested that although banned, there could be illegal usage of chloramphenicol antibiotic in local aquaculture. The bacteria in aquaculture may have spread to other environmental water through disposal of aquaculture waste water to other environments.

Matched MeSH terms: Intention
Fulltext Level of satisfaction in using the hospital information system among staff of a teaching hospital in Malaysia

Sangaran, G., Ahmad Taufik, J., Aniza, I.

Malaysian Journal of Public Health Medicine, 2014;14(1):29-38.
MyJurnal

Hospital information systems have evolved with the recent widespread, involving technology and target functions, and this involves the critical computer systems from multiple perspectives. Healthcare organizations increasingly use information technology as a basis for improving productivity and user satisfaction. A research had been done about the level of satisfaction in using the Hospital Information System. Data was obtained by using a set of questionnaires that have been tested for reliability and validity. The staff are comprised of two (2) categories: Nurses (community nurses / Head nurse / staff nurse, nurse managers and others) while the second category consists of administrative officers (administrative officers, administrative assistants and clerks) in selected departments. Variables consist of sociodemographic factors, occupational factors and perception factors. A total of 152 respondents identified using stratified sampling method. The factors studied were age, gender, marital status, level of qualifications, length of service, knowledge of the system, attitude towards the use of the system, behavioral intention to use the system and compatibility with work. Majority of respondents were females (88.2%). The level of satisfaction among the staff in using the hospital information system is high (88.8%) compared to the dissatisfied staff in UKMMC (11.2%). In overall, the staffs in UKMMC are satisfied using the hospital information system available now but there are always a room for improvement so that the system can be used more intensively.

Matched MeSH terms: Intention
Fulltext Job-demand resources model to explain the relationship among work-family conflict, burnout, social support and turnover intention: a conceptual review

Hamid, R. A., Ungku Ahmad, U. N. K.

Journal of Advanced Research Design, 2014;1(1):42-53.
MyJurnal

This paper reviews the conceptualization and relationship among work-family conflict,
burnout, social support and turnover intention using Job Demand Resources (JD-R) model. From the
theoretical framework of JD-R model, there is a relationship between job demand and resources that
gives impact to organization outcome. In addition, empirical evidence also shows that a relationship
exists between the above variables. Organization should address proactively how job demand and
resources influence each other that lead to organization outcome. Comprehensive understanding
regarding the above matter gives opportunity for organizations to take reasonable action to ensure
employees well-being and give benefit to the organizations themselves.

Matched MeSH terms: Intention
Fulltext Predictors of intention to stay for employees of casual dining restaurant in Klang Valley area

Nasyira, M.N., Othman, M., Ghazali, H.

International Food Research Journal, 2014;21(3):863-871.
MyJurnal

Employees are an asset to an organisation where they could be the determinant behind organisational’s success or failure in an industry. In this study, the relationship between perceived organisational support (POS), perceived supervisor support (PSS), and organisational commitment (OC) with employee’s intention to stay with their current jobs were studied. For that purpose, 717 questionnaires were collected among casual dining restaurants employees in Klang Valley area and analyses Pearson correlation and multiple linear regression were run by using SPSS version 21. The results suggest that POS, PSS, and OC were positively correlated with employee’s intention to stay with their current job. Furthermore, OC was also found to be the most influential factor in affecting employees’ staying intention. The finding is hoped to have important implications where the management can formulate strategies to retain employees in restaurant industry in Malaysia.

Matched MeSH terms: Intention
Eigenstructure-based angle for detecting outliers in multivariate data

Nazrina Aziz

Sains Malaysiana, 2014;43:1973-1977.

There are two main reasons that motivate people to detect outliers; the first is the researchers' intention; see the example of Mr Haldum's cases in Barnett and Lewis. The second is the effect of outliers on analyses. This article does not differentiate between the various justifications for outlier detection. The aim was to advise the analyst about observations that are isolated from the other observations in the data set. In this article, we introduce the eigenstructure based angle for outlier detection. This method is simple and effective in dealing with masking and swamping problems. The method proposed is illustrated and compared with Mahalanobis distance by using several data sets.

Matched MeSH terms: Intention
Fulltext Chronic tibial osteomyelitis in children. A case review at hospital tengku ampuan afzan, kuantan

Shukrimi A, Ariff MS, Zamzuri Z, Mai Ashikin NT

Med J Malaysia, 2015 Feb;70(1):48-51.
PMID: 26032532 MyJurnal

Osteomyelitis in children has various clinical manifestations causing diagnostic and therapeutic difficulties. Inappropriate treatment of acute osteomyelitis may lead to chronic, serious and complicated condition. Chronic osteomyelitis continues to be a major cause of morbidity and disability in children living in developing countries. We present three cases of tibial osteomyelitis that have different presentations and sequalae. Our intention is to alert our colleagues, particularly primary physicians, regarding the variety of presentation and the important of early diagnosis and treatment to reduce the risk of morbidity following osteomyelitis.

Matched MeSH terms: Intention
The Two-Brains Hypothesis: Towards a guide for brain-brain and brain-machine interfaces

Goodman G, Poznanski RR, Cacha L, Bercovich D

J Integr Neurosci, 2015 Sep;14(3):281-93.
PMID: 26477360 DOI: 10.1142/S0219635215500235

Great advances have been made in signaling information on brain activity in individuals, or passing between an individual and a computer or robot. These include recording of natural activity using implants under the scalp or by external means or the reverse feeding of such data into the brain. In one recent example, noninvasive transcranial magnetic stimulation (TMS) allowed feeding of digitalized information into the central nervous system (CNS). Thus, noninvasive electroencephalography (EEG) recordings of motor signals at the scalp, representing specific motor intention of hand moving in individual humans, were fed as repetitive transcranial magnetic stimulation (rTMS) at a maximum intensity of 2.0[Formula: see text]T through a circular magnetic coil placed flush on each of the heads of subjects present at a different location. The TMS was said to induce an electric current influencing axons of the motor cortex causing the intended hand movement: the first example of the transfer of motor intention and its expression, between the brains of two remote humans. However, to date the mechanisms involved, not least that relating to the participation of magnetic induction, remain unclear. In general, in animal biology, magnetic fields are usually the poor relation of neuronal current: generally "unseen" and if apparent, disregarded or just given a nod. Niels Bohr searched for a biological parallel to complementary phenomena of physics. Pertinently, the two-brains hypothesis (TBH) proposed recently that advanced animals, especially man, have two brains i.e., the animal CNS evolved as two fundamentally different though interdependent, complementary organs: one electro-ionic (tangible, known and accessible), and the other, electromagnetic (intangible and difficult to access) - a stable, structured and functional 3D compendium of variously induced interacting electro-magnetic (EM) fields. Research on the CNS in health and disease progresses including that on brain-brain, brain-computer and brain-robot engineering. As they grow even closer, these disciplines involve their own unique complexities, including direction by the laws of inductive physics. So the novel TBH hypothesis has wide fundamental implications, including those related to TMS. These require rethinking and renewed research engaging the fully complementary equivalence of mutual magnetic and electric field induction in the CNS and, within this context, a new mathematics of the brain to decipher higher cognitive operations not possible with current brain-brain and brain-machine interfaces. Bohr may now rest.

Matched MeSH terms: Intention
Consumer purchase intention towards environmentally friendly vehicles: an empirical investigation in Kuala Lumpur, Malaysia

Afroz R, Masud MM, Akhtar R, Islam MA, Duasa JB

Environ Sci Pollut Res Int, 2015 Oct;22(20):16153-63.
PMID: 26070739 DOI: 10.1007/s11356-015-4841-8

This paper examines whether attitudes towards electric vehicles (ATEVs), subjective norms (SNs) and perceived behavioural control (PBC) have significant associations with consumer purchase intention (PI) and the purchase behaviour of environmentally friendly vehicles (EFVs). The results from the survey questionnaires are analysed using confirmatory factor analysis (CFA) and structural equation modelling (SEM). The findings of this paper indicate that ATEV, SN and PBC significantly influence PI. This finding also indicates that environmental consequence and individual preferences do not influence the PI of the respondents. We found that Malaysian car owners are largely unaware of the greenhouse effects on the environment or attach to it little importance, which is reflected in their PI towards EFVs. The outcomes of this study could help policymakers design programmes to influence attitudes, subjective norms, perceived behavioural control and purchase behaviour to prevent further air pollution and reduce CO2 emissions from the transportation sector.

Matched MeSH terms: Intention*
Another Important News from the Neuronman: Malaysia's Neuroscience Group Moves upwards in Terms of Research, Creativity, and Innovation

Abdullah JM

Malays J Med Sci, 2015 Dec;22(Spec Issue):1-4.
PMID: 27006631

12 months ago the first Neuroscience special issue of the Malaysia Journal of Medical Sciences was born with the intention to increase the number of local publication dedicated to neurosciences. Since then many events happened in the neuroscience world of Malaysia, those considered major were the establishment of a Neurotechnology Foresight 2050 task force by the Academy of Medicine Malaysia as well as the launching of Malaysia as the 18th member to join the International Neuroinformatics Coordinating Facility on the 9th October 2015 which was officiated by the Deputy Ministers of Higher Education, Datuk Mary Yap.

Matched MeSH terms: Intention
Common misconceptions and future intention to smoke among secondary school students in Malaysia

Caszo B, Khair M, Mustafa MH, Zafran SN, Syazmin N, Safinaz RN, et al.

Asian Pac J Cancer Prev, 2015;16(3):1159-64.
PMID: 25735348

BACKGROUND: The prevalence of smoking among secondary school children continues to remain unchanged over the last 3 decades even though awareness regarding the health effects of smoking is increasing. Common misconceptions about smoking and parental influence could be factors influencing future intentions to smoke among these students. Hence, we looked at the common misconceptions as well as student perceptions about their future intention to smoke among Form 4 students in Shah Alam, Malaysia.
MATERIALS AND METHODS: This study was conducted by distribution of a questionnaire developed as part of the Global Youth Tobacco Survey to Form 4 student in 3 schools at Shah Alam.
RESULTS: Prevalence of smoking (current smokers) was 7.5%. Almost half of the children came from families where one or both parents smoked and a third of the parents had no discussion regarding consequences of smoking with them. A large number of students were classified as "triers" as they had tried smoking and were unsure of whether they would not be smoking in the future. Contrary to our expectations, students generally felt smoking did make one feel more uncomfortable and helped one to reduce body weight. Most students seemed to be aware of the ill-effects of smoking on health. They felt they had received adequate information from school regarding the effects on smoking on health.
CONCLUSIONS: Our study showed that even though Form 4 students in Shah Alam were knowledgeable about ill-effects of smoking and were taught so as part of their school curriculum, the prevalence of smoking was still high. Students in the "trier group" represent a potential group of future smokers and strategies targeting tobacco control may be aimed at tackling these vulnerable individuals. Efforts are also needed to help educate secondary school children about common misconceptions and dispel myths associated with cigarette smoking.

Matched MeSH terms: Intention*
Social Marketing in Malaysia: Cognitive, Affective, and Normative Mediators of the TAK NAK Antismoking Advertising Campaign

Lee WB, Fong GT, Dewhirst T, Kennedy RD, Yong HH, Borland R, et al.

J Health Commun, 2015;20(10):1166-76.
PMID: 26054867 DOI: 10.1080/10810730.2015.1018565

Antismoking mass media campaigns are known to be effective as part of comprehensive tobacco control programs in high-income countries, but such campaigns are relatively new in low- and middle-income countries and there is a need for strong evaluation studies from these regions. This study examines Malaysia's first national antismoking campaign, TAK NAK. The data are from the International Tobacco Control Malaysia Survey, which is an ongoing cohort survey of a nationally representative sample of adult smokers (18 years and older; N = 2,006). The outcome variable was quit intentions of adult smokers, and the authors assessed the extent to which quit intentions may have been strengthened by exposure to the antismoking campaign. The authors also tested whether the impact of the campaign on quit intentions was related to cognitive mechanisms (increasing thoughts about the harm of smoking), affective mechanisms (increasing fear from the campaign), and perceived social norms (increasing perceived social disapproval about smoking). Mediational regression analyses revealed that thoughts about the harm of smoking, fear arousal, and social norms against smoking mediated the relation between TAK NAK impact and quit intentions. Effective campaigns should prompt smokers to engage in both cognitive and affective processes and encourage consideration of social norms about smoking in their society.

Matched MeSH terms: Intention
Within-family discussion on harmful effects of smoking and intention to initiate smoking among European adolescents

Masood M, Masood Y, Md Sabri BA, Younis LT, Yusof N, Reidpath D, et al.

J Addict Med, 2015 Jul-Aug;9(4):261-5.
PMID: 26241085 DOI: 10.1097/ADM.0000000000000127

OBJECTIVE: The main objective of this study was to determine the impact of discussion within family about the harmful effects of smoking on intention to initiate smoking in the long term among nonsmoking adolescents.
METHODS: Data from Global Youth Tobacco Survey for 25 European countries were used. The outcomes of interest were, therefore, the intention to initiate smoking 1 and 5 years after the survey. Discussion within family about harmful effect of smoking was the main predictor with age, sex, and smoking status of parents, friends, and classmates as covariates. The association between predictors and outcomes was assessed through multiple regression analysis.
RESULTS: A total of 118,703 nonsmoking adolescents were included. Within-family discussion significantly reduced the odds of intention to initiate smoking 1 and 5 years later. Intention to initiate smoking also was significantly associated with the smoking status of friends, classmates, and parents, except for father's smoking status, which was not associated with intention to initiate 1 year later.
CONCLUSIONS: This study demonstrated that within-family discussion about the harmful effects of smoking may contribute to reduce the intention to start smoking among adolescents in the long term. Such a discussion was associated with reduced intention to smoke even when adjusting for parent/friend and classmate smoking.

Matched MeSH terms: Intention
Fulltext Job satisfaction and turnover intention among Iraqi doctors--a descriptive cross-sectional multicentre study

Ali Jadoo SA, Aljunid SM, Dastan I, Tawfeeq RS, Mustafa MA, Ganasegeran K, et al.

Hum Resour Health, 2015;13:21.
PMID: 25903757 DOI: 10.1186/s12960-015-0014-6

BACKGROUND: During the last two decades, the Iraqi human resources for health was exposed to an unprecedented turnover of trained and experienced medical professionals. This study aimed to explore prominent factors affecting turnover intentions among Iraqi doctors.
METHODS: A descriptive cross-sectional multicentre study was carried out among 576 doctors across 20 hospitals in Iraq using multistage sampling technique. Participants completed a self-administered questionnaire, which included socio-demographic information, work characteristics, the 10-item Warr-Cook-Wall job satisfaction scale, and one question on turnover intention. Descriptive and bivariate and multiple logistic regression analyses were conducted to identify significant factors affecting turnover intentions.
RESULTS: More than one half of Iraqi doctors (55.2%) were actively seeking alternative employment. Factors associated with turnover intentions among doctors were low job satisfaction score (odds ratio (OR) = 0.97; 95% confidence interval (CI): 0.95, 0.99), aged 40 years old or less (OR = 2.9; 95% CI: 1.74, 4.75), being male (OR = 4.2; 95% CI: 2.54, 7.03), being single (OR = 5.0; 95% CI: 2.61, 9.75), being threatened (OR = 3.5; 95% CI: 1.80, 6.69), internally displaced (OR = 3.1; 95% CI: 1.43, 6.57), having a perception of unsafe medical practice (OR = 4.1; 95% CI: 1.86, 9.21), working more than 40 h per week, (OR = 2.3; 95% CI: 1.27, 4.03), disagreement with the way manager handles staff (OR = 2.2; 95% CI: 1.19, 4.03), being non-specialist, (OR = 3.9, 95% CI: 2.08, 7.13), and being employed in the government sector only (OR = 2.0; 95% CI: 1.09, 3.82).
CONCLUSION: The high-turnover intention among Iraqi doctors is significantly associated with working and security conditions. An urgent and effective strategy is required to prevent doctors' exodus.

Matched MeSH terms: Intention*
Fulltext Use of the united theory of acceptance and use of technology model to study information communication technology - adoption in five Saudi Arabian private hospitals

Amnah, A.B., Bulgiba, A., Omar, R.

JUMMEC, 2015;18(2):1-7.
MyJurnal

We conducted a multi-institutional case study to identify the issues associated with the adoption of information and communication technology (ICT) in five private care hospitals in the Kingdom of Saudi Arabia. We conducted interviews with 37 respondents primarily comprising IT professionals.
We found that there were three determinants of behavioural intentions in this case study: organisation objectives, facilitating conditions and social influence where there are no effects of performance expectancy or effort expectancy. In all five cases, none of the moderators (age, gender, experience and voluntariness) in the original united theory of acceptance and use of technology model were considered critically important by IT professionals. In the present paper, all qualitative elements such as themes, patterns and overarching in the data were analysed to reach a conclusion. In addition, the various perspectives of using ICT are discussed.

Matched MeSH terms: Intention
Fulltext Indoor plants as a filtration of indoor air pollution: a review

Mohd Mahathir Suhaimi Shamsuri, Leman, A.M.

Journal of Occupational Safety and Health, 2015;12(2):41-48.
MyJurnal

Indoor pollution increasingly becomes a public concern. These concerns are related to energy efficiency in a
building. There are various ways in which it can ensure energy conservation can be achieved, including superinsulation
and reduced fresh air exchange. As a result, indoor air becomes stagnant and odours, thereafter contaminants of air will
accumulate and will certainly disrupt human health. It is quite difficult to make people comfortable in a building with
consumption of energy-saving and human health guaranteed. Indoor plants are one of the alternative solutions that
have been studied since the last three decades. This paper intends to review the abilities of indoor plants to purify air,
and the ways used by previous researchers to prove that indoor plants can treat the air. In general, it can be stated that
indoor plants are able to absorb various types of volatile organic compounds (VOCs). An advantage of indoor plants
to cure air from carcinogen gas is greatly needed for human health. Therefore, studies on indoor plants to neutralize
the air are gaining attention. Enclosed space or chamber is often used by researchers to test the ability of indoor plants
absorb gaseous toxins in their study; because it is easy to handle and can quickly determine the absorption rate. In the
other hand, environmental factors such as temperature, humidity, and light are important to be taken into consideration
during the study. As a conclusion, it can be stated that the existence of indoor plants in a building is very reasonable,
because it can give positive impacts on human health and the total energy consumption.

Matched MeSH terms: Intention
Life cycle inventory of institutional medium-scaled co-composting of food waste and yard waste in tropical country

Chee Guan Ng, Sumiani Yusoff

Sains Malaysiana, 2015;44:517-527.

The main objective of the present study was to provide a comprehensive LCI of medium scale composting of food waste
and yard waste at institutional level, based on substance flow analysis (SFA). A secondary objective was to present the
composition and assess the quality of the final compost product from composting of typical Asian organic waste (food
waste and yard waste). The experiments were designed to represent a batch situation in an institutional medium size
composting scenario with input material of food waste mixed with grass clippings and dried leaves. Two composting
runs were carried out with the intention to showcase the heterogeneity of organic waste and study the effect of windrow
size on the performance of the process. The input and output material were sampled and characterized in order to
quantify the substance balance of the process. SFA was performed by means of the mass balance model STAN 2.5 to
compute unknown parameters (gaseous emissions). SFAs have been performed for C, N, K, P, Cd, Cr, Cu, Ni and Pb. The
composting windrows were fed with 212.4 and 393 kg, respectively. VS content reduction is greater in composting pile
with larger size (Run 2). The loss of C during composting was recorded in the range of 0.146-0.166 kg/kg ww. The C
losses via leachate were insignificant (0.02% of the total input C). The total N loss during the process was 0.005-0.012
kg/kg ww. The leachate generation was measured as 0.012-0.013 kg/kg ww. The flows of selected heavy metals were
assessed. Heavy metals were of minor significance due to low concentrations in the inputs (food waste and yard waste).
Heavy metals were found to be released to the atmosphere. However, majority of heavy metals remain in the finished
compost. The C/N reduction during the process was in the range of 10-23%. In general, the compost composition was
considered to be within the ranges previously reported in literature and thus ready for application in gardening. The LCI
presented in the present study can be used as a starting point for making environmental assessments of medium-scale
co-composting of food waste and yard waste in tropical environment. No major environmental problems were identified
from the process, except for the emissions of GHGs.

Matched MeSH terms: Intention
The Mediating Effects of Organizational Justice in Determining the Relationship between Performance-Based Pay and Employees’ Turnover Intention

Kuan Mei Yang, Rusli Ahmad, Siti Mariam Abdullah

Journal of Cognitive Sciences & Human Development, 2015;1(1):1-10.
MyJurnal

This is a study on employees’ perception of justice towards performance-based pay and
the effect of these perceptions on their turnover intention. This study aims to examine
the mediating role played by distributive and procedural justice in linking pay distribution
and pay procedure of performance-based pay to employees’ turnover intention. A
review of past literature in this particular area has prompted the researchers to narrow
the gaps in previous studies. Towards that, this study utilized questionnaires which
were administered among 50 non-managerial employees currently working in a private
company located in Kuching, Sarawak, East Malaysia. Data analysis was done using
Statistical Package for Social Sciences (SPSS), Version 20.0. Pearson Correlation and
Stepwise Regression were used to examine the relationship between the variables. The
outcomes of Stepwise Regression revealed that distributive justice fully mediated the
relationship between pay distribution and employees’ turnover intention in contrast to
procedural justice which did not have a significant impact in the relationship. The findings
of this study are useful references for organisation management of the pay system
to improve employees’ performance.

Matched MeSH terms: Intention
Fulltext The extended Theory of Planned Behavior in explaining exclusive breastfeeding intention and behavior among women in Kelantan, Malaysia

Tengku Ismail TA, Wan Muda WA, Bakar MI

Nutr Res Pract, 2016 Feb;10(1):49-55.
PMID: 26865916 DOI: 10.4162/nrp.2016.10.1.49

The purpose of this study is to utilize an extended Theory of Planned Behavior in identifying predictors of exclusive breastfeeding intention and behavior among women in Kelantan, Malaysia.

Matched MeSH terms: Intention
International Patients' Travel Decision Making Process- A Conceptual Framework

Khan MJ, Chelliah S, Haron MS

Iran J Public Health, 2016 Feb;45(2):134-45.
PMID: 27114978

BACKGROUND: Role of information source, perceived benefits and risks, and destination image has significantly been examined in travel and tourism literature; however, in medical tourism it is yet to be examined thoroughly. The concept discussed in this article is drawn form well established models in tourism literature.
METHODS: The purpose of this research was to identify the source of information, travel benefits and perceived risks related to movement of international patients and develop a conceptual model based on well-established theory. Thorough database search (Science Direct, utmj.org, nih.gov, nchu.edu.tw, palgrave-journals, medretreat, Biomedcentral) was performed to fulfill the objectives of the study.
RESULTS: International patients always concern about benefits and risks related to travel. These benefits and risks form images of destination in the minds of international patients. Different sources of information make international patients acquaint about the associated benefits and risks, which later leads to development of intention to visit. This conceptual paper helps in establishing model for decision-making process of international patients in developing visit intention.
CONCLUSION: Ample amount of literature is available detailing different factors involved in travel decision making of international patients; however literature explaining relationship between these factors is scarce.

Matched MeSH terms: Intention
The efficacy of blueberry and grape seed extract combination on triple therapy for Helicobacter pylori eradication: a randomised controlled trial

Chua CS, Yang KC, Chen JH, Liu YH, Hsu YH, Lee HC, et al.

Int J Food Sci Nutr, 2016 Mar;67(2):177-83.
PMID: 26883189 DOI: 10.3109/09637486.2016.1144716

Helicobacter pylori is a major risk factor for gastritis, gastric ulcers and gastric cancer. Traditional therapy with proton pump inhibitor and antibiotics is regarded as optimal for H. pylori eradication whereas, the eradication rate is unsatisfactory. Studies have reported that cranberry may inhibit H. pylori adhesion to the human gastric mucus but lack of other berry extracts have been evaluated in clinical study. Thus, a 9-week add-on randomised controlled trial was conducted to explore the impact of blueberry and grape seed extract (BGE) combinations traditional therapy for H. pylori eradication. In results, we found that there was no significant difference of eradication rate between the berry extract group and placebo group in the intention-to-treat analysis and in the per-protocol analysis (94.64% versus 84.62%, p = 0.085). Diarrhoea, constipation and epigastric pain were observed increasing during ingestion of the berry extract in some cases. In conclusion, this study indicated that no significant difference existed between the BGE extract group and placebo group in eradication rate under triple therapy.

Matched MeSH terms: Intention to Treat Analysis

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