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Prevalence and Characteristics of Taste Disorders in Cases of COVID-19: A Meta-analysis of 29,349 Patients

Saniasiaya J, Islam MA, Abdullah B

Otolaryngol Head Neck Surg, 2021 07;165(1):33-42.
PMID: 33320033 DOI: 10.1177/0194599820981018

OBJECTIVE: The purpose of this meta-analysis is to assess the pooled prevalence of taste disorders and their subtypes in patients with COVID-19.
DATA SOURCES: PubMed, Scopus, Web of Science, Embase, and Google Scholar databases were searched to identify studies published between December 1, 2019, and June 23, 2020, without language restrictions. There was no restriction on the study design; therefore, observational studies, clinical trials, and case series were included. In addition, preprints were considered if data of interest were reported.
REVIEW METHODS: Two authors independently screened articles for eligibility. A random effects model was used to estimate the pooled prevalence with 95% CIs. Quality assessment was done with critical appraisal tools of the Joanna Briggs Institute. The robustness of the pooled estimates was checked by subgroup and sensitivity analyses.
RESULTS: Fifty-nine studies were included (N = 29,349 patients, 64.4% female). The pooled prevalence of taste disorders in patients with COVID-19 was 48.1% (95% CI, 41.3%-54.8%). The prevalence of taste disorders in studies with objective assessments was higher as compared with subjective assessments (59.2% vs 47.3%). The disorders were observed in 55.2% of European patients; 61.0%, North American; 27.1%, Asian; 29.5%, South American; and 25.0%, Australian. Ageusia, hypogeusia, and dysgeusia were detected in 28.0%, 33.5%, and 41.3% of patients with COVID-19. We identified 91.5% of the included studies as high quality.
CONCLUSIONS: The prevalence of taste disorders in patients with COVID-19 was 48.1%. Objective assessments have higher prevalence than subjective assessments. Dysgeusia is the most common subtype, followed by ageusia and hypogeusia.

Matched MeSH terms: Prevalence
Fulltext Food choices among Malaysian adults: Findings from Malaysian Adults Nutrition Survey (MANS) 2003 and MANS 2014

Mohamad Kasim N, Ahmad MH, Shaharudin AB, Naidu BM, Chan YY, Aris T

Malays J Nutr, 2018;24(1):63-75.
MyJurnal

Introduction: Changes in dietary habits are known to be associated with changes in health outcomes. This study determined food choices among Malaysian adults using secondary data of the Malaysian Adults Nutrition Survey (MANS) in 2003 and MANS in 2014.
Methods: A total of 6,742 and 3,000 adults aged 18 to 59 years participated in MANS 2003 and MANS 2014, respectively. Both studies used a semi-quantitative food frequency questionnaire (FFQ) to assess habitual food intake.
Results: Overall, the prevalence of adults consuming rice twice daily were 97.3% and 86.9% in 2003 and 2014, respectively. While the percentage of urban dwellers who consumed rice daily differed significantly between 2003 (96.7%) and 2014 (86.9%), the percentage remained quite similar among rural adults in 2003 (97.8%) and 2014 (96.3%). Other top ten food items consumed daily were sugar (2003, 58.5% vs 2014, 55.9%), marine fish (40.8% vs 29.4%), green leafy vegetables (39.9% vs 43.2%) and sweetened condensed milk (35.2% vs 29.3%). In both surveys, a higher percentage of men consumed rice, sugar and sweetened condensed milk on a daily basis compared to women, a higher proportion of whom daily consumed green leafy vegetables and marine fish. Majority of the adults reported drinking plain water daily. Other beverages taken daily were tea, coffee and chocolate-malt drinks.
Conclusion: Rice, sugar and sweetened condensed milk were among the top food items consumed daily in 2003 and 2014. Educational efforts to improve dietary intake of Malaysian adults is recommended.
Study name: Malaysian Adult Nutrition Survey (MANS-2003); Malaysian Adult Nutrition Survey (MANS-2014)

Matched MeSH terms: Prevalence
Fulltext Parasitic Gregarine blattarum Found Infecting American Cockroaches, Periplaneta americana, in a Population in Pulau Pinang, Malaysia

Yahaya ZS, Izzaudin NA, Razak AF

Trop Life Sci Res, 2017 Jan;28(1):145-149.
PMID: 28228922 MyJurnal DOI: 10.21315/tlsr2017.28.1.10

A study on the prevalence of a common endoparasite in the wild population of the American cockroach was conducted in Penang Island using a trapping method at several sampling sites on the island. Gregarine blattarum was found in the digestive tract in 5 out of 115, or 4.35%, of the wild American cockroaches, Periplaneta americana, that were sampled. This is the first report in Malaysia of Gregarine blattarum in local American cockroaches.

Matched MeSH terms: Prevalence
Global status of Toxoplasma gondii infection: systematic review and prevalence snapshots

Molan A, Nosaka K, Hunter M, Wang W

Trop Biomed, 2019 Dec 01;36(4):898-925.
PMID: 33597463

Our group sought to determine the global status of T. gondii infection and to evaluate any continental and geographical trends by systematically examining the currently available epidemiological data on the prevalence of T. gondii infection. A comprehensive literature search was conducted from 10 electronic databases (Google Scholar, Science Direct, Embase, PubMed, PLOS ONE, Web of Knowledge, SciELO, MyAIS, Free Medical Journals, and Scopus) without date or language restrictions. Specific medical subject heading terms were used to search for human T. gondii seroprevalence studies that recruited subjects from general apparently healthy populations. The data were collated and analysed for both continental and global trends. The search identified 152 published studies that examined a total of 648,010 subjects. From these, 166,255 were seropositive for T. gondii infection indicating an average global seroprevalence rate of 25.7% (95% CI: 25.6 - 25.8%). The overall range of seroprevalence was determined to be 0.5 - 87.7%. African countries had the highest average seroprevalence rate of 61.4%, followed by Oceania with 38.5%, South America with 31.2%, Europe with 29.6%, USA/Canada with 17.5%, and Asia with 16.4%. Numerous environmental and human factors affect the differences in T. gondii seroprevalence rates observed between the various countries and continents. Monitoring the source and transmission may assist public health authorities to clarify the risk factors involved, as well as focus on implementing optimal state-specific health policies targeting T. gondii transmission control.

Matched MeSH terms: Prevalence
Fulltext Toxin gene profiling of methicillin-susceptible Staphylococcus au

Hui-min, Neoh, Saberi Saimun, Hassriana Fazilla Sapr, Salasawati Hussin, Rahman Jamal

Asia-Pacific Journal of Molecular Medicine, 2017;7(2):1-3.
MyJurnal

Entero- and exfoliative toxin gene profiling of 237 methicillin-susceptible Staphylococcus aureus (MSSA) isolated
from Universiti Kebangsaan Malaysia Medical Centre (UKMMC) were carried out via PCR amplification. Among
the tested toxin genes, sei was found to be the most prevalent (54.9%).

Matched MeSH terms: Prevalence
Fulltext Animal models of metabolic syndrome: a review

Wong SK, Chin KY, Suhaimi FH, Fairus A, Ima-Nirwana S

Nutr Metab (Lond), 2016;13:65.
PMID: 27708685 DOI: 10.1186/s12986-016-0123-9

Metabolic syndrome (MetS) consists of several medical conditions that collectively predict the risk for cardiovascular disease better than the sum of individual conditions. The risk of developing MetS in human depends on synergy of both genetic and environmental factors. Being a multifactorial condition with alarming rate of prevalence nowadays, establishment of appropriate experimental animal models mimicking the disease state in humans is crucial in order to solve the difficulties in evaluating the pathophysiology of MetS in human. This review aims to summarize the underlying mechanisms involved in the pathophysiology of dietary, genetic, and pharmacological models of MetS. Furthermore, we will discuss the usefulness, suitability, pros and cons of these animal models. Even though numerous animal models of MetS have been established, further investigations on the invention of new animal model and clarification of plausible mechanisms are still necessary to confer a better understanding to researchers on the selection of animal models for their studies.

Matched MeSH terms: Prevalence
Fulltext Life events and parasuicides in Hospital Kuala Lumpur, Malaysia

Hamidin, A., Maniam, T.

Malaysian Journal of Medicine and Health Sciences, 2011;7(2):45-52.
MyJurnal

Objective: The aim of this study is to compare the prevalence of life events among parasuicide patients
with the prevalence of similar life events among age, sex and race matched patients with non-chronic
medical illness. Methods: A hospital-based case-control study using convenience sampling method
was conducted in Hospital Kuala Lumpur for a period of three and a half months. A total of 50 patients
admitted consecutively after an episode of parasuicide and who fulfilled criteria for entry into the study
agreed to participate. For each case one age-, sex- and race-matched control was selected from the list of patients who were admitted to the same hospital for non-chronic medical illness. Result: Statistical analysis showed that compared with medically ill patients, parasuicide patients had significantly higher prevalence of threatening life events six months (p

Matched MeSH terms: Prevalence
Fulltext The association between myopia and gender in Indian schoolchildren in Kuala Lumpur

Norhani Mohidin, Saadah Mohd Akhir, Bariah Mohd Ali, Zainora Mohammed, Sharanjeet, K., Chung, K.M.

Jurnal Sains Kesihatan Malaysia, 2005;3(2):49-54.
MyJurnal

A vision screening study was carried out among Indian schoolchildren around Kuala Lumpur to determine whether the prevalence of myopia was higher in boys or girls. Altogether 749 students (49.7% boys and 50.3% girls) aged 7-18 years were screened and their refractive error examined using retinoscopy without cycloplegia. For the right eye 15.1% of the girls' eyes were found to be myopic as compared to 16.9% of the boys, of which chi-square showed no significant difference (p = 0.44). For the left eye 18.8% of the girls' eyes were myopic as compared to 16.4% of the boys. Chi square also showed no significant difference (p = 0.26). When high myopia (> -6.00D) was considered, there was no difference found between boys and girls. The number of students with high myopia greater than -6.00D was also very small (0.3%-0.5%). In conclusion, it was found that there was no significant difference in myopia between girls and boys among Indian schoolchildren.

Matched MeSH terms: Prevalence
Fulltext Bacillus cereus and Bacillus thuringiensis in ready-to-eat cooked rice in Malaysia

Sandra, A., Afsah-Hejri, L., Tunung, R., Tuan Zainazor, T. C., Tang, J. Y. H., Ghazali, F. M., et al.

International Food Research Journal, 2012;19(3):829-836.
MyJurnal

Bacillus cereus (B. cereus) isolates are toxigenic and can cause food poisoning. Cooked rice is
a potentially hazardous food, especially in tropical countries. The aim of this study was to determine the prevalence of B. cereus and B. thuringiensis in raw and cooked rice marketed in Selangor, Malaysia. In this research combination of Most Probable Number - Polymerase Chain Reaction (MPN-PCR) was used to detect gyrB gene in B. cereus and B. thuringiensis. Five local varieties of raw rice samples were negative for B. thuringiensis but all (100%) were positive for B. cereus. A total of 115 cooked rice samples (nasi lemak, nasi briyani, nasi ayam and nasi putih) were studied for the presence of B. cereus and B. thuringiensis. Nasi ayam was found to have the highest prevalence (100%) of B. cereus compared to nasi putih (76.2%) and nasi lemak (70.4%). Nasi briyani had the lowest prevalence (50%) of B. cereus. The frequencies of B. thuringiensis were found to be 10, 30 and 35.2 % in nasi putih and nasi ayam, nasi briyani and nasi lemak, respectively. The range of B. cereus and B. thuringiensis in the samples was from < 3 to 1100 MPN/g in different samples. Maximum number of B. cereus was observed in nasi lemak, nasi briyani and nasi putih ( > 1100 MPN/g) while nasi ayam showed less contamination (460 MPN/g) with B. cereus which was significantly different (P < 0.05 ) from others. The number of B. thuringiensis in nasi lemak, nasi briyani, nasi putih and nasi ayam were found to be >1100, 93, 9.2 and 3.6 MPN/g, respectively.

Matched MeSH terms: Prevalence
Fulltext The prevalence of Actinobacillus actinomycetemcomitans in a healthy Malay population in Malaysia

Zahari, N.M., Ismail, R., Bunyarit, S.S., Shafiei, Z., Al Rawenduzy, K.C.M.A.

Malaysian Dental Journal, 2007;28(1):45-50.
MyJurnal

Actinobacillus actinomycetemcomitans is considered a major pathogen in periodontal disease. The aim of this study was to determine the prevalence of A. actinomycetemcomitans from 46 subjects aged 20-24 years old of who were all periodontally healthy Malays.

Matched MeSH terms: Prevalence
Fulltext Prevalence of Campylobacter spp. in retailed ready-to-eat sushi

Tan, Y.F., Haresh, K.K., Chai, L.C., Ghazali, F.M., Son, R.

International Food Research Journal, 2008;15(3):331-336.
MyJurnal

The prevalence of Campylobacter spp. in retailed sushi were examined using the techniques of polymerase chain reaction (PCR) in combination with most probable number (MPN) to quantify the bacteria in 150 samples obtained from three supermarkets. The average prevalence of Campylobacter spp. in retailed sushi was 26.6% with 32%, 16% and 32% from supermarket I, II and III, respectively. Campylobacter jejuni was found to be the predominant species in retailed sushi with 82.49% of all Campylobacter spp. positive samples. Campylobacter coli was not detected in all samples. The maximum MPN number of Campylobacter spp. in retailed sushi purchased from supermarket I, II and III ranged from 3.6-11.0 MPN/g, 9.4->1100 MPN/g and 27-1100 MPN/g, respectively. The isolation of C. jejuni from a variety of ready-to-eat retail sushi may indicate that these products can act as possible vehicles for the dissemination of food-borne campylobacteriosis.

Matched MeSH terms: Prevalence
Fulltext Management of a maxillary first molar tooth with unusual mesiobuccal root anatomy

Hany Mohamed Aly Ahmed, Deepti Saini

Archives of Orofacial Sciences, 2012;7(2):101-106.
MyJurnal

Sufficient knowledge on the root and root canal anatomy is essential for practicing root canal treatment. The mesiobuccal roots of maxillary molar teeth present an endodontic challenge due to their wide variability and complexity of their internal morphological landmarks. A review on the literature indicates that the prevalence of a third mesiobuccal root canal in the mesiobuccal root of maxillary molar teeth may reach 9%, and the root canal configuration usually is type XV (3-2). These reported data reveal the importance of absolute awareness for this anatomical aberration that requires special attention from dental practitioners while commencing root canal treatment in maxillary molar teeth. Hence, this article aims to report and describe the management of a maxillary first molar tooth with three mesiobuccal root canals, but with an unusual configuration.

Matched MeSH terms: Prevalence
Fulltext Acrylic partial dentures fixed to adjacent teeth: a case report on quack dentistry

Nik Madihah Nik Azis, Khamiza Zainol Abidin

Archives of Orofacial Sciences, 2015;10(1):41-45.
MyJurnal

The practice of quack dentistry worldwide is a challenge to the profession of dentistry as it undermines the trust of the general public and places the patients at unnecessary risks through their illegal practices. Although the ratio of patients to dentists is rapidly decreasing in Malaysia due to the increased output of qualified dentists from both local and foreign institutions, quack dentistry is still practiced in many areas. This report intends to highlight a popular treatment prescribed by these quack dentists which is removable partial dentures that is fixed to the adjacent teeth by cold cure acrylic. We also aim to discuss the design of the denture and the means employed to remove this ’fixed partial denture’. It is hoped that this case report will highlight the prevalence of the practice of quack dentistry especially in geographical area of this case report and allow the authorities to devise means to stop this illegal practice.

Matched MeSH terms: Prevalence
Fulltext Prevalence Of Developmental Defects Of Enamel Among 16-Year-Old Children In Malaysia

Nik Hussien, N.N., Majid, Z.A., Mutalib, K.A., Abdullah, F., Abang, A., Wan, M.N.

Ann Dent, 1999;6(1):-.
MyJurnal

The prevalence of developmental defects of enamel was assessed in 4805 16-year-old schoolchildren in fluoridated and non-fluoridated areas in Malaysia. In this sample, the mouth prevalence was 56.0%; tooth prevalence was 21.8%. There were significant differences between children in fluoridated and non-fluoridated areas, urban and rural areas as well as between the ethnic groups. However, there was no significant gender difference. Prevalences were lower than those reported in most other Asiancountries. However, direct comparisons could not be madedue to differences in indices and methodology used.

Matched MeSH terms: Prevalence
Fulltext Classification, Epidemiology And Aetiology Of Oral Recurrent Aphtous Ulceration / Stomatitis

Zain, R.B.

Ann Dent, 1999;6(1):-.
MyJurnal

The most prevalent oral mucosal lesions are aphthous ulcerations commonly referred to as canker sores. The clinical characteristic of oral recurrent aphthous ulceration/stomatitis(ORAS) is well defined and can be partly described as an oval or rounded ulcer covered by a grey-white or yellowish fibrinous exudate and surrounded by an erythematous halo. There is intense or moderate pain and the ulcers heal in about 10 - 14 days for the more common type and more than 2 weeks for the severe type. Recurrence of the ulcers occurs at intervals within a year or over several years. Variations of ORAS described above have made studies on aetiology and treatment difficult to interpret due to differing descriptions of differing diseases with similar clinical signs and symptoms and possibly differing aetiologies. A classification that was considered useful as a working model for ORAS was formulated in 1978. While the classification of ORAS had been widely accepted since 1978, the cause for ORAS is still unknown and its aetiology in general remains unclear. However, its immunopathogenesis is now becoming more clearly defined.

Matched MeSH terms: Prevalence
Fulltext Odontogenic Keratocysts in a Malaysian Population: Clinical, Radiological and Histological Considerations

Ong, Siew Tin, Chong, Huat Siar

Ann Dent, 1995;2(1):-.
MyJurnal

This paper represents a study of35casesofodontogenic keratocyst (OKC) diagnosed in a Malaysian population. The clinical, radiological and histopathological features, treatment modalities and recurrence of this lesion were analysed. There was a higher prevalence rate among Malaysian Chinese (51.42 percent), while the Malays and Indians accounted for22.86 percent and 25.72 percent respectively. The male to female ratio was 16 : 19.Age at presentation ranged from nine to 71 year,with about 70percent occurring between ages ten to 39 years. A total of40cysts were analysed. Of these, 67.5 percent occurred in the mandible and 32.5 percent in the maxilla. About 88percent of OKC presented as unilocular radiolucencies and 42.0 percent were associated with unerupted or impacted teeth. Histologically, the parakeratinized OKC was the predominant variant found (75.8 percent). The majority of caseswere treated by enucleation (85 percent), and a recurrence rate of20percent was recorded.

Matched MeSH terms: Prevalence
Fulltext Evidence-based clinical recommendations for fluoride use: a review

Mani, Shani Ann

Archives of Orofacial Sciences, 2009;4(1):1-6.
MyJurnal

The use of fluoride as a preventive measure for dental caries has been established more than 50 years ago. The recommendations for fluoride use has been modified over the years due to factors like decreased prevalence of caries, increased prevalence of dental fluorosis and the widespread availability of fluoride in various forms to the community. In recent years, the role of evidence-based recommendations has come to the forefront, in an attempt to ensure the most favorable treatment for the individual. This review has attempted to appraise the most recent evidence- based recommendations for different fluoride modalities put forth by various organizations worldwide, in order to appreciate the current status of fluoride in the early 21st century.

Matched MeSH terms: Prevalence
Studies of the nutritional anaemias of Malaya: the prevalence of iron deficiency

TASKER PW

Trans R Soc Trop Med Hyg, 1955 Sep;49(5):478-82.
PMID: 13267915
Matched MeSH terms: Prevalence
Oral Health Interventions Using Chlorhexidine-Effects on the Prevalence of Oral Opportunistic Pathogens in Stroke Survivors: A Randomized Clinical Trial

Ab Malik N, Abdul Razak F, Mohamad Yatim S, Lam OLT, Jin L, Li LSW, et al.

J Evid Based Dent Pract, 2018 06;18(2):99-109.
PMID: 29747810 DOI: 10.1016/j.jebdp.2017.08.002

OBJECTIVE: To evaluate the presence of oral opportunistic pathogens among stroke survivors, both before and after oral health care interventions.
METHODS: A multicenter randomized clinical trial was conducted on hospitalized stroke survivors. Those in the control group were given standard care of oral hygiene (a manual toothbrush and toothpaste), whereas those in the test group were given intense care of oral hygiene (a powered toothbrush and 1% chlorhexidine oral gel). Oral clinical assessments were carried out, and microbiological samples were collected, using concentrated oral rinse samples at 3 time points: baseline, 3 months, and 6 months.
RESULTS: The prevalence of oral yeast was significantly reduced in the test group at 6 months (P < .05), but no significant difference was observed over time. A significant reduction was observed in the prevalence of Staphylococcus aureus (P < .01) and aerobic and facultative gram-negative bacilli over time (P < .05), but there were no significant differences noted between groups at 6 months. Candida albicans and Klebsiella pneumoniae were the prominent pathogens determined throughout the trial. Kluyvera strains have also been isolated from this cohort.
CONCLUSION: Oral hygiene intervention using a powered tooth brush and 1% chlorhexidine oral gel was effective in reducing the prevalence of oral opportunistic pathogens.

Matched MeSH terms: Prevalence
Fulltext An audit of the referral letter received at Klinik Pakar Orthodontik Jln Abd Samad [Abstract]

Mohamed Zini SH, Nordin N

International Medical Journal Malaysia, 2017;16(21):36.
MyJurnal

Introduction: The objectives of this study were to determine the prevalence and the pattern of hypodontia among orthodontic patients in Klinik Pergigian Jalan Sultan Mahmud, Kuala Terengganu.
Materials and Methods: This was a retrospective study where 351 orthodontic patients records (comprises of 104 males and 247 females), were reviewed. The records were evaluated by a trained dental officer between October 2016 and June 2017. The Chi-square and Fisher's Exact Tests were carried out for statistical analysis.
Results: The prevalence of hypodontia was 10.8%. Thirty-eight (38) patients were found to have at least a single missing tooth. A significant difference was found between males and females having hypodontia (p = 0.048). No significant difference was found for hypodontia patients by races (p = 0.829). The maxillary lateral incisor was the most frequently missing tooth followed by mandibular second premolar and mandibular lateral incisor. Hypodontia cases observed, tended to be more likely occurred in the upper left arch compared to the lower arch. The majority of hypodontia patients had a single missing tooth, but rarely more than 3 missing teeth. Hypodontia patients had mainly Class III malocclusion, however no statistically significant difference was found (p = 0.081).
Conclusion(s): The prevalence of hypodontia of this study was within the range of what is being reported in the literature and showed gender significant. In this sample, hypodontia mainly involved maxillary lateral incisors; more prevalent in the upper arch; and mostly observed in patients with Class III malocclusion. Early detection and accurate diagnosis are essential. Therefore, alternative treatment modalities can be well planned under multidisciplinary team approach in restoring the aesthetic and function.
KEYWORDS: referral letter

Matched MeSH terms: Prevalence

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