Displaying publications 1 - 20 of 2347 in total

  1. Almasi D, Sadeghi M, Lau WJ, Roozbahani F, Iqbal N
    Mater Sci Eng C Mater Biol Appl, 2016 Jul 01;64:102-107.
    PMID: 27127033 DOI: 10.1016/j.msec.2016.03.053
    The present work reviews the current fabrication methods of the functionally graded polymeric material (FGPM) and introduces a novel fabrication method that is versatile in applications as compared to those of existing used methods. For the first time electrophoresis was used to control the distribution of the tetracycline hydrochloride (TC) in a film made of polylactic acid (PLA), aiming to induce antimicrobial effect on the film prepared. The elemental analysis on the film surface showed that by employing electrophoresis force, higher amount of TC was detected near the top surface of the film. Results also showed that the FGPM samples with higher percentage of the TC on the film surface were highly effective to minimize the growth of Escherichia coli. These findings are useful and important to improve dispersion quality of the particles in the composite material and further enhance its antibacterial property.
    Matched MeSH terms: Escherichia coli/growth & development*
  2. Sivanandam S, Sandosham AA
    Med J Malaya, 1968 Mar;22(3):238.
    PMID: 4234713
    Matched MeSH terms: Filarioidea/growth & development*
  3. Cheong WH, Sta Maria FL
    Med J Malaya, 1968 Mar;22(3):244-5.
    PMID: 4234380
    Matched MeSH terms: Anopheles/growth & development*
  4. Bisseru B, Poopalachelvam M
    Med J Malaya, 1968 Mar;22(3):234-5.
    PMID: 4234370
    Matched MeSH terms: Strongyloides/growth & development*
  5. Nadchatram M, Audy JR
    Med J Malaya, 1965 Sep;20(1):80-1.
    PMID: 4221435
    Matched MeSH terms: Mites/growth & development*
  6. Thomas V
    Med J Malaya, 1966 Jun;20(4):335.
    PMID: 4224349
    Matched MeSH terms: Insects/growth & development*
  7. Umathevy T
    Med J Malaya, 1965 Sep;20(1):58.
    PMID: 4221419
    Matched MeSH terms: Echinostoma/growth & development*
  8. Ong CH, Tham CL, Harith HH, Firdaus N, Israf DA
    Eur J Pharmacol, 2021 Nov 15;911:174510.
    PMID: 34560077 DOI: 10.1016/j.ejphar.2021.174510
    Transforming growth factor-beta (TGF-β) plays multiple homeostatic roles in the regulation of inflammation, proliferation, differentiation and would healing of various tissues. Many studies have demonstrated that TGF-β stimulates activation and proliferation of fibroblasts, which result in extracellular matrix deposition. Its increased expression can result in many fibrotic diseases, and the level of expression is often correlated with disease severity. On this basis, inhibition of TGF-β and its activity has great therapeutic potential for the treatment of various fibrotic diseases such as pulmonary fibrosis, renal fibrosis, systemic sclerosis and etc. By understanding the molecular mechanism of TGF-β signaling and activity, researchers were able to develop different strategies in order to modulate the activity of TGF-β. Antisense oligonucleotide was developed to target the mRNA of TGF-β to inhibit its expression. There are also neutralizing monoclonal antibodies that can target the TGF-β ligands or αvβ6 integrin to prevent binding to receptor or activation of latent TGF-β respectively. Soluble TGF-β receptors act as ligand traps that competitively bind to the TGF-β ligands. Many small molecule inhibitors have been developed to inhibit the TGF-β receptor at its cytoplasmic domain and also intracellular signaling molecules. Peptide aptamer technology has been used to target downstream TGF-β signaling. Here, we summarize the underlying mechanism of TGF-β-induced fibrosis and also review various strategies of inhibiting TGF-β in both preclinical and clinical studies.
    Matched MeSH terms: Transforming Growth Factor beta*
  9. Selvarajoo PD, Haque RA, Haziz UFM, Avicor SW, Wajidi MFF, Razali MR
    J Inorg Biochem, 2017 10;175:232-238.
    PMID: 28800547 DOI: 10.1016/j.jinorgbio.2017.07.030
    New synthesized bis-imidazolium salts that are linked by xylyl derivatives moiety, 1-4 was reacted with Ag2O to facilitate the formation of dinuclear Ag(I)-N-heterocyclic carbene (NHC) complexes, 5-8, respectively. All the synthesized ligand salts and complexes were characterized by1H and13C NMR, FTIR spectroscopy and elemental analysis. Molecular structures of compounds 3, 5, and 7 were elucidated by single crystal X-ray diffraction analyses. Larvicidal studies against the Aedes aegypti and Culex quinquefasciatus were carried out on all synthesized compounds following the World Health Organization standard larval susceptibility test. All the imidazolium salts were found inactive while the activity of the dinuclear Ag(I)-NHC complexes on mosquito larvae are varies with the nature of the ligands. Complex 7 has high activity on Ae. aegypti and Cx. quinquefasciatus, emphasising its potential as a larvicidal compound.
    Matched MeSH terms: Aedes/growth & development*; Culex/growth & development*; Larva/growth & development
  10. Cheong WH, Mahadevan S
    Med J Malaya, 1968 Mar;22(3):241.
    PMID: 4234376
    Matched MeSH terms: Anopheles/growth & development*; Culex/growth & development*
  11. Hamad AM, Taha RM
    Pak J Biol Sci, 2008 Feb 01;11(3):386-91.
    PMID: 18817160
    Seven different hormone treatments, namely 6-benzylaminopurine (BAP) at 2, 3 mg L(-1) was applied singly and in combination with Indole Acetic Acid (IAA) at 0.18, 0.8 and 1.8 mg L(-l), BAP at 3.3 mg L(-l) in combination with IAA at 1.8 and 3.3 mg L(-l) and triple combination of BAP at 2.3, IAA at 1.8 and Gibberellic acid (GA3) at 1.0 mg L(-1) were tested, over four different incubation periods of 30, 45, 60 and 75 days, for their effect in the proliferation and growth of Smooth cayenne pineapple shoot-tip culture. Combined application of BAP at 3.3 and IAA at 1.8 mg L(-1) induced the highest proliferation of 19 shoots/explant and the highest total of 121 and 125 shoots over 4 cycles of multiplication. Raising the IAA to 3.3 mg L(-1) resulted in the lowest proliferation and stunted shoots. Incorporation of GA3 improved the shoot length but caused drastic reduction in proliferation. The other treatments showed an intermediate effect.
    Matched MeSH terms: Plant Growth Regulators/pharmacology*; Plant Shoots/growth & development*; Ananas/growth & development*
  12. Thevasagayam ES, Khoon CC, Siong Y
    Med J Malaysia, 1979 Dec;34(2):117-30.
    PMID: 548712
    Matched MeSH terms: Anopheles/growth & development*; Diptera/growth & development*
  13. Kian Joe Lie, Umathevy T
    J Parasitol, 1965 Oct;51(5):793-9.
    PMID: 5857279
    Matched MeSH terms: Echinostoma/growth & development*; Trematoda/growth & development*
  14. Jamil NAM, Gomes C, Kadir Z, Gomes A
    Electromagn Biol Med, 2020 Oct 01;39(4):356-363.
    PMID: 32878496 DOI: 10.1080/15368378.2020.1812080
    Corona discharge from multiple needles at an electrical potential of 5 kV generated by a Van de Graff generator increased the growth rate of the mycelium of tiger's milk mushroom by 10.3% at the end of the first eight days. A similar growth rate enhancement was observed for the next eight days as well. Mycelium of tiger's milk mushroom was cultured on agar media in Petri dish for five days prior to the exposure to various forms of electrical stimulations. The direct current injection (1.1-1.3 A) to the growing medium, application of an electric potential to the growing environment at low strength (30 V) and high strength (5 kV) with single and multiple needles showed varying degrees of success. This suggests that the mycelium of tiger's milk mushroom could positively be stimulated by specific electrical stimulation techniques with selected parameters. This will pave the way to a highly beneficial growth enhancement technique that can be up-scaled to apply in mass production of mushroom.
    Matched MeSH terms: Polyporaceae/growth & development*; Mycelium/growth & development*
  15. Burgess AJ, Retkute R, Pound MP, Mayes S, Murchie EH
    Ann Bot, 2017 03 01;119(4):517-532.
    PMID: 28065926 DOI: 10.1093/aob/mcw242
    Background and Aims: Intercropping systems contain two or more species simultaneously in close proximity. Due to contrasting features of the component crops, quantification of the light environment and photosynthetic productivity is extremely difficult. However it is an essential component of productivity. Here, a low-tech but high-resolution method is presented that can be applied to single- and multi-species cropping systems to facilitate characterization of the light environment. Different row layouts of an intercrop consisting of Bambara groundnut ( Vigna subterranea ) and proso millet ( Panicum miliaceum ) have been used as an example and the new opportunities presented by this approach have been analysed.

    Methods: Three-dimensional plant reconstruction, based on stereo cameras, combined with ray tracing was implemented to explore the light environment within the Bambara groundnut-proso millet intercropping system and associated monocrops. Gas exchange data were used to predict the total carbon gain of each component crop.

    Key Results: The shading influence of the tall proso millet on the shorter Bambara groundnut results in a reduction in total canopy light interception and carbon gain. However, the increased leaf area index (LAI) of proso millet, higher photosynthetic potential due to the C4 pathway and sub-optimal photosynthetic acclimation of Bambara groundnut to shade means that increasing the number of rows of millet will lead to greater light interception and carbon gain per unit ground area, despite Bambara groundnut intercepting more light per unit leaf area.

    Conclusions: Three-dimensional reconstruction combined with ray tracing provides a novel, accurate method of exploring the light environment within an intercrop that does not require difficult measurements of light interception and data-intensive manual reconstruction, especially for such systems with inherently high spatial possibilities. It provides new opportunities for calculating potential productivity within multi-species cropping systems, enables the quantification of dynamic physiological differences between crops grown as monoculture and those within intercrops, and enables the prediction of new productive combinations of previously untested crops.

    Matched MeSH terms: Panicum/growth & development; Vigna/growth & development
  16. Lai KM, Goh BH, Lee WL
    Growth Factors, 2021 03 15;38(3-4):167-176.
    PMID: 33719806 DOI: 10.1080/08977194.2021.1895144
    Cell entry of influenza A virus (IAV) was reported to be promoted by epidermal growth factor receptor (EGFR). On the other hand, binding of heparin-binding EGF-like growth factor (HB-EGF) to EGFR leads to internalisation and degradation of the receptors. This study aimed to testify whether or not HB-EGF-induced downregulation of EGFR could attenuate IAV cell entry and subsequently diminish the infection. Immunoblotting and plaque assay revealed that HB-EGF-induced degradation of EGFR led to reduction of viral matrix 1 protein level and suppressed virion production. In addition, immunoblotting and imaging flow cytometric analysis demonstrated that IAV-induced phosphorylation of STAT1 and its localisation to nucleus in the early stage of infection were inhibited by HB-EGF treatment. This suggested the potential of HB-EGF in modulating uncontrolled and exaggerated inflammatory response caused by IAV infection. Together these findings attest the potential of HB-EGF mediated endocytosis and degradation of EGFR as a novel anti-IAV strategy.
    Matched MeSH terms: Epidermal Growth Factor*; Heparin-binding EGF-like Growth Factor
  17. Koh LP, Miettinen J, Liew SC, Ghazoul J
    Proc Natl Acad Sci U S A, 2011 Mar 22;108(12):5127-32.
    PMID: 21383161 DOI: 10.1073/pnas.1018776108
    Rising global demands for food and biofuels are driving forest clearance in the tropics. Oil-palm expansion contributes to biodiversity declines and carbon emissions in Southeast Asia. However, the magnitudes of these impacts remain largely unquantified until now. We produce a 250-m spatial resolution map of closed canopy oil-palm plantations in the lowlands of Peninsular Malaysia (2 million ha), Borneo (2.4 million ha), and Sumatra (3.9 million ha). We demonstrate that 6% (or ≈880,000 ha) of tropical peatlands in the region had been converted to oil-palm plantations by the early 2000s. Conversion of peatswamp forests to oil palm led to biodiversity declines of 1% in Borneo (equivalent to four species of forest-dwelling birds), 3.4% in Sumatra (16 species), and 12.1% in Peninsular Malaysia (46 species). This land-use change also contributed to the loss of ≈140 million Mg of aboveground biomass carbon, and annual emissions of ≈4.6 million Mg of belowground carbon from peat oxidation. Additionally, the loss of peatswamp forests implies the loss of carbon sequestration service through peat accumulation, which amounts to ≈660,000 Mg of carbon annually. By 2010, 2.3 million ha of peatswamp forests were clear-felled, and currently occur as degraded lands. Reforestation of these clearings could enhance biodiversity by up to ≈20%, whereas oil-palm establishment would exacerbate species losses by up to ≈12%. To safeguard the region's biodiversity and carbon stocks, conservation and reforestation efforts should target Central Kalimantan, Riau, and West Kalimantan, which retain three-quarters (3.9 million ha) of the remaining peatswamp forests in Southeast Asia.
    Matched MeSH terms: Trees/growth & development*; Arecaceae/growth & development*
  18. Mondal MM, Puteh AB, Malek MA, Ismail MR, Rafii MY, Latif MA
    ScientificWorldJournal, 2012;2012:425168.
    PMID: 22919319 DOI: 10.1100/2012/425168
    Growth parameters such as leaf area (LA), total dry mass (TDM) production, crop growth rate (CGR), relative growth rate (RGR), and net assimilation rate (NAR) were compared in six varieties of mungbean under subtropical condition (24°8' N 90°0' E) to identify limiting growth characters for the efficient application of physiology breeding for higher yields. Results revealed that a relatively smaller portion of TDM was produced before flower initiation and the bulk of it after anthesis. The maximum CGR was observed during pod filling stage in all the varieties due to maximum leaf area (LA) development at this stage. Two plant characters such as LA and CGR contributed to the higher TDM production. Results indicated that high yielding mungbean varieties should possess larger LA, higher TDM production ability, superior CGR at all growth stages, and high relative growth rate and net assimilation rate at vegetative stage which would result in superior yield components.
    Matched MeSH terms: Fabaceae/growth & development; Seeds/growth & development*; Crops, Agricultural/growth & development
  19. Ravi R, Rajendran D, Oh WD, Mat Rasat MS, Hamzah Z, Ishak IH, et al.
    Sci Rep, 2020 11 06;10(1):19245.
    PMID: 33159109 DOI: 10.1038/s41598-020-75054-0
    Four different tests showed the effectiveness of Azolla pinnata plant extracts against Aedes aegypti and Aedes albopictus mosquitoes. In the adulticidal test, there was a significant increase in mortality as test concentration increases and A. pinnata extracts showed LC50 and LC95 values of 2572.45 and 6100.74 ppm, respectively, against Ae. aegypti and LC50 and LC95 values of 2329.34 and 5315.86 ppm, respectively, against Ae. albopictus. The ovicidal test showed 100% eggs mortality for both species tested for all the concentrations tested at 1500 ppm, 1000 ppm, 500 ppm, 250 ppm and 125 ppm. Both tested samples of Ae. aegypti and Ae. albopictus did not lay any eggs in the plastic cups filled with the A. pinnata extract but instead opted to lay eggs in the plastic cups filled with water during the oviposition deterrence test. Similarly, the non-choice test of Ae. aegypti mosquitoes laid eggs on the sucrose solution meant for the nutrient source of the mosquitoes instead of in the plastic cup that was designed to facilitate oviposition filled with the extract. This clearly indicates the presence of bioactive compounds which are responsible in adulticidal and ovicidal activity in Aedes mosquitoes and at the same time inducing repellence towards the mosquitoes. The LC-MS results showed mainly three important chemical compounds from A. pinnata extracts such as 1-(O-alpha-D-glucopyranosyl)-(1,3R,25R)-hexacosanetriol, Pyridate and Nicotinamide N-oxide. All these chemicals have been used for various applications such as both emulsion and non-emulsion type of cosmetics, against mosquito vector such as Culex pipens and Anopheles spp. Finally, the overall view of these chemical components from A. pinnata extracts has shown the potential for developing natural product against dengue vectors.
    Matched MeSH terms: Aedes/growth & development*; Anopheles/growth & development*; Culex/growth & development*
  20. Nathan L
    Family Practitioner, 1983;6:33-38.
    Matched MeSH terms: Growth and Development
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