Displaying publications 1 - 20 of 26 in total

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  1. Chan CK, Lee HY, Choi WC, Cho JY, Lee SH
    Eur Spine J, 2011 Jul;20 Suppl 2:S217-21.
    PMID: 20938789 DOI: 10.1007/s00586-010-1585-5
    Sciatica-like leg pain can be the main presenting symptom in patients with cervical cord compression. It is a false localizing presentation, which may lead to missed or delayed diagnosis, resulting in the wrong plan of management, especially in the presence of concurrent lumbar lesions. Medical history, physical findings and the results of imaging studies were reviewed in two cases of cervical cord compressions, which presented with sciatica-like leg pain. There was multi-level cervical spondylosis with cord compression in the first patient and the second patient had two levels of cervical disc herniation with cord compression. In both cases, there were co-existing lumbar lesions, which could be responsible for the presentation of the leg pain. Cervical blocks were diagnostic in identifying the level responsible for the leg pain and it was confirmed so after cervical decompressive surgery in both cases, which brought significant pain relief. Funicular leg pain is a rare presentation of cervical cord compression. It is a referred pain due to the irritation of the ascending spinothalamic tract. Cervical blocks were successful in identifying the cause of funicular pain in our cases and this may pave the way for further studies to establish the role of cervical blocks as a diagnostic tool for funicular pain caused by cord compression.
    Matched MeSH terms: Spinal Cord Compression/complications*; Spinal Cord Compression/physiopathology; Spinal Cord Compression/surgery
  2. Rashid MZ, Ariffin MH, Rhani SA, Baharudin A, Ibrahim K
    Malays Orthop J, 2017 Nov;11(3):53-55.
    PMID: 29326769 MyJurnal DOI: 10.5704/MOJ.1711.005
    Osteoradionecrosis, a rare complication of radiation therapy, is a slow progression disease which affects the surrounding structures of spinal components. It essentially weakens the soft tissue and bony configuration and can cause nerve impingement or cord compression. We describe a patient who underwent radiotherapy for thyroid cancer and presented with cervical kyphosis with anterolisthesis of C3/C4 and C4/C5 some 32 years later. We explore the role of anterior and posterior fusion, as well as hyperbaric oxygen therapy in promoting healing.
    Matched MeSH terms: Spinal Cord Compression
  3. Yusof ZB, Pratap RC
    Aust N Z J Med, 1990 Oct;20(5):697-8, 700.
    PMID: 2126728
    We describe a case of cervical cord compression due to ossified posterior longitudinal ligament in association with diffuse idiopathic skeletal hyperostosis, in a young female. Characteristic CT findings are described.
    Matched MeSH terms: Spinal Cord Compression/etiology*
  4. Wong TS, Abdul Rashid ML, Hasan MS, Chiu CK, Chan CYW, Kwan MK
    J Orthop Surg (Hong Kong), 2019 4 9;27(2):2309499019840763.
    PMID: 30955474 DOI: 10.1177/2309499019840763
    The presence of anatomical anomalies such as absence of C1 posterior arch and presence of C2 high-riding vertebral artery may not allow a conventional C1-C2 fusion, and this patient will require occipitocervical fusion. A 62-year-old lady presented with cervical myelopathy. CT scan demonstrated an os odontoideum with C1-C2 dislocation. The posterior arch of atlas on right C1 vertebra was absent, and there was high-riding vertebral artery on left C2. MRI revealed severe cord compression with cord oedema. The chronic atlantoaxial dislocation was reduced successfully with skeletal traction. Hybrid C1-C2 fusion augmented with autogenous local bone graft with corticocancellous iliac crest bone graft was performed to avoid an unnecessary occipitocervical fusion. She was stable throughout surgery and discharged 6 days later. CT scan 6 months post-operation showed a solid posterior fusion mass. Hybrid C1-C2 fusion can be performed to avoid occipitocervical fusion despite presence of abnormal anatomy at C1 and C2 vertebrae.
    Matched MeSH terms: Spinal Cord Compression/diagnosis; Spinal Cord Compression/etiology; Spinal Cord Compression/surgery*
  5. Manmohan S, Nor Azlin ZA, Fazir M, Dzulkarnain A, Goh JH
    Malays Orthop J, 2015 Mar;9(1):32-34.
    PMID: 28435594 MyJurnal DOI: 10.5704/MOJ.1503.004
    Instances of neurological recovery after early decompression of the spine in non-traumatic spinal cord compression are well documented. We present a patient with paraplegia of 11 months' duration due to atypical spinal tuberculosis who showed complete neurological recovery in three months.
    Matched MeSH terms: Spinal Cord Compression
  6. Sahathevan R, Tan HJ, Abdullah S, Shahizon AM, Hamidon BB, Raymond AA
    Med J Malaysia, 2011 Dec;66(5):495-6.
    PMID: 22390109 MyJurnal
    We describe a case of tetraparesis in a 33-year-old woman following neck manipulation performed by a traditional confinement mid-wife. An MRI of the cervical spine revealed a fracture of the second cervical vertebra with atlanto-axial subluxation that resulted in cord compression.
    Matched MeSH terms: Spinal Cord Compression/diagnosis; Spinal Cord Compression/etiology*
  7. Hasmoni MH, Wahid FA, Keng CS
    South. Med. J., 2009 Jan;102(1):101-3.
    PMID: 19077786 DOI: 10.1097/SMJ.0b013e31818018c1
    Plasma cell leukemia (PCL) is a rare plasma cell disorder. It is the leukemic variant of multiple myeloma. A 52-year-old man with an atypical presentation of primary plasma cell leukemia is reported. The patient presented with paraparesis which progressively worsened to paraplegia. MRI of the spine showed an extradural mass causing cord compression and multiple bony erosions from soft tissue masses. Peripheral blood film examination and bone marrow aspiration showed numerous plasmablasts. Atypical cells expressed surface and cytoplasmic lambda light chain on immunochemical studies, surface CD45 and CD38. To our knowledge, primary PCL presenting with progressive paraplegia has not been reported in the literature.
    Matched MeSH terms: Spinal Cord Compression/etiology*; Spinal Cord Compression/pathology
  8. Mustafa M, Subramanian N
    Int Orthop, 1996;20(6):383-4.
    PMID: 9049770
    We describe a patient with acute compression of the spinal cord by a spontaneous extra-dural haematoma. This rare condition is often misdiagnosed. We believe that an urgent MRI scan is indicated in patients presenting with progressive neurological deficit following spinal trauma. This allows the diagnosis of extra-dural haematoma to be made rapidly and for prompt decompression of the cord.
    Matched MeSH terms: Spinal Cord Compression/diagnosis; Spinal Cord Compression/etiology*
  9. Chooi YS, Siow YS, Chong CS
    J Bone Joint Surg Br, 2005 Feb;87(2):257-9.
    PMID: 15736753
    We report a case of vertebral osteochondroma of C1 causing cord compression and myelopathy in a patient with hereditary multiple exostosis. We highlight the importance of early diagnosis and the appropriate surgery in order to obtain a satisfactory outcome.
    Matched MeSH terms: Spinal Cord Compression/etiology; Spinal Cord Compression/surgery
  10. Monteiro ES
    Matched MeSH terms: Spinal Cord Compression
  11. Jolina, W.N., Dazlin Masdiana, S., Afliza, A.B.
    Medicine & Health, 2018;13(2):188-194.
    MyJurnal
    Warfarin is an anticoagulant that is commonly used as thrombo-prophylaxis in patients at risk of thrombo-embolic events. However, the use of warfarin is known to cause hemorrhage due to its anticoagulation effect. Although the common sites of hemorrhage are gastrointestinal and genitourinary tract, it can also occur in the least expected location. We report a rare case of spinal cord compression secondary to intraspinal epidural hematoma as a result of overwarfarinization in a patient who had undergone liver transplant. The patient underwent emergency decompression laminectomy of spinal cord and hematoma evacuation after the reversal of overwarfarinization to normal levels.
    Matched MeSH terms: Spinal Cord Compression
  12. Rohana AG, Norasyikin AW, Suehazlyn Z, Ming W, Norlela S, Norazmi MK
    Med J Malaysia, 2006 Dec;61(5):638-40.
    PMID: 17623970 MyJurnal
    We report a case of a 65 year old Malay lady with long-standing diabetes mellitus, who presented to our institution with a one month history of worsening neck pain and progressive upper and lower limb weakness. She was stable despite severe hyponatraemia which was initially treated as syndrome of inappropriate anti-diuretic hormone (SIADH). This was consistent with her underlying illness which was concluded as cervical tuberculosis (TB) with spinal cord compression. She underwent decompression and bone grafting. Despite continuous treatment her serum sodium levels remained low. There were no other problems with her adrenals or thyroid. A water loading and hypertonic saline perfusion test was performed and supported the diagnosis of reset osmostat. Her serum sodium remained below the normal range and she was discharged well.
    Matched MeSH terms: Spinal Cord Compression/surgery*
  13. Tan GH, Tan KK, Afian MS, Liew WF, Mohamad AR
    Med J Malaysia, 2005 Jul;60 Suppl C:111-3.
    PMID: 16381295
    We report a case of upper cervical instability associated with Down syndrome to highlight its potential progression to inflict cord compression and the rationale for surgical decompression and extended short segment occipito-axial fusion.
    Matched MeSH terms: Spinal Cord Compression/etiology
  14. Arumugasamy N
    Med J Malaya, 1969 Jun;23(4):250-2.
    PMID: 4242169
    Matched MeSH terms: Spinal Cord Compression/etiology*
  15. Lorna Ting KN, Liew YT, Abu Bakar Z, Narayanan P
    Auris Nasus Larynx, 2019 Jun;46(3):469-473.
    PMID: 30049634 DOI: 10.1016/j.anl.2018.07.002
    Nasopharyngeal carcinoma is a neoplasm commonly found in population of South East Asia. The mainstay of treatment is high dose irradiation. Complications from radiotherapy are not uncommon especially to those nearby structures such as vertebrae and spinal cord. A 57 year-old gentleman with nasopharyngeal carcinoma (NPC) who was treated with chemo-radiation (total of 35 fractions,70Gy) presented to us 6 months post therapy with bilateral nasal discharge and progressive neck stiffness. Nasoendoscopy showed inflamed nasophayngeal mucosa and Computed Tomography (CT) brain and cervical spine showed retropharyngeal and anterior epidural collection with extension into atlantoaxial bone and spinal cord compression. Histopathological specimen revealed features of chronic inflammations with multiple actinomycetes colonies. Our patient suffered severe neck stiffness and loss of sensations on both upper limbs. He was treated conservatively with Halo vest and intravenous antibiotics for 8 weeks and recovered fully. Irradiation in NPC is known to cause devastating complications to cervical spine such as osteoradionecrosis, osteomyelitis. It also renders tissues hypoxic and risk of getting rare infection like actinomycosis. This report can represent a great diagnostic and therapeutic challenge with differentials of tumor recurrence, osteoradionecrosis or osteomyelitis. Patients must be regularly followed up to look for possible cervical complications as a result from irradiation, to prevent devastating outcome or prognosis.
    Matched MeSH terms: Spinal Cord Compression/etiology
  16. Tan SH, Ganesan D, Prepageran N, Waran V
    Eur Arch Otorhinolaryngol, 2014 Nov;271(11):3101-5.
    PMID: 24986428 DOI: 10.1007/s00405-014-3149-5
    Matched MeSH terms: Spinal Cord Compression/diagnosis; Spinal Cord Compression/surgery*
  17. Puraviappan P, Tang IP, Yong DJ, Prepageran N, Carrau RL, Kassam AB
    J Laryngol Otol, 2010 Jul;124(7):816-9.
    PMID: 20003599 DOI: 10.1017/S0022215109992271
    Tuberculosis can cause extensive osseo-ligamentous destruction at the cranio-vertebral junction, leading to atlanto-axial instability and compression of vital cervico-medullary centres. This may manifest as quadriparesis, bulbar dysfunction and respiratory insufficiency.
    Matched MeSH terms: Spinal Cord Compression/etiology; Spinal Cord Compression/surgery*
  18. Julia PE, Nazirah H
    Spinal Cord, 2007 Dec;45(12):804-5.
    PMID: 17710102
    Case report.
    Matched MeSH terms: Spinal Cord Compression/complications; Spinal Cord Compression/pathology
  19. Khan ESKBM, Thean CAP, Zakaria ZB, Awang MSB, Karupiah RK, Awang MB
    J Orthop Case Rep, 2020;10(2):101-105.
    PMID: 32953668 DOI: 10.13107/jocr.2020.v10.i02.1718
    Introduction: Spinal schwannoma can occur anywhere along the spinal cord but is predominantly seen in the cervical and thoracic region.It composes mainly of well-differentiated schwann cell and is benign in nature. It is typically seen in the peripheral nerves and is commonly associated with neurofibromatosis. Up to 80% of cases, spinal schwannoma is reported to be intradural in location and 15% of cases have both intradural and extradural components. Spinal schwannoma rarely causes conus medullaris syndrome.

    Case Report: In this case series, all three female patients in their 4th and 5th decades of life presented with conus medullaris syndrome. Lower back pain, radiculopathy, lower limb weakness, and urinary incontinence are their main clinical presentation. Magnetic resonance imaging shows a well-defined intradural, extramedullary mass compressing onto the conus medullary region. These patients undergone microscopic assisted excision of the tumor and had remarkably good early outcome despite the advanced presentation of neurological deficit.

    Conclusion: Despite the late presentation with significant neurological deficit, surgical excision of spinal schwannomas carries a good prognosis postoperatively due to their benign nature and extramedullary location.

    Matched MeSH terms: Spinal Cord Compression
  20. Muhammad Wafiuddin
    MyJurnal
    Prostate carcinoma is a common health issue that can metastasise in the spine. A 65-year-old male was diagnosed with prostate carcinoma and two years later he developed a progressive neurological deficit over the bilateral lower limb. He experienced severe back pain, became paraplegic and the quality of life was severely impaired. Radiographic investigations were done and revealed osteoblastic bone metastasis at thoracic vertebrae with spinal cord compression. The patient underwent surgical decompression surgery at the T9 level mainly for pain control. Six months post-surgery not only the pain was well controlled but patient able to ambulate with walking aid. It is a rare post-operative result as the neurological recovery in a patient with complete paralysis is less than 3%. This type of recovery is possible when the cause of the neurological deficit is mainly mechanical compression from tumour rather than cord ischaemia from traumatic injury.
    Matched MeSH terms: Spinal Cord Compression
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