Displaying publications 1 - 20 of 75 in total

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  1. Akram S, Najam R, Rizwani GH, Abbas SA
    Pak J Pharm Sci, 2015 Sep;28(5):1781-7.
    PMID: 26408897
    This study depicts a profile of existence of heavy metals (Cu, Ni, Zn, Cd, Hg, Mn, Fe, Na, Ca, and Mg) in some important herbal plants like (H. Integrifolia, D. regia, R. communis, C. equisetifolia, N. oleander, T. populnea, M. elengi, H. schizopetalus, P. pterocarpum) from Pakistan and an antidiabetic Malaysian herbal drug product containing (Punica granatum L. (Mast) Hook, Momordica charantia L., Tamarindus indica L., Lawsonia inermis L.) using atomic absorption spectrophotometer. Heavy metals in these herbal plants and Malaysian product were in the range of 0.02-0.10 ppm of Cu, 0.00-0.02 ppm of Ni, 0.02-0.29 ppm of Zn, 0.00-0.04 ppm of Cd, 0.00-1.33 ppm of Hg, 0.00-0.54 ppm of Mn, 0.22-3.16 ppm of Fe, 0.00-9.17 ppm of Na, 3.27-15.63 ppm of Ca and 1.85-2.03 ppm of Mg. All the metals under study were within the prescribed limits except mercury. Out of 10 medicinal plants/product under study 07 were beyond the limit of mercury permissible limits. Purpose of this study is to determine heavy metals contents in selected herbal plants and Malaysian product, also to highlight the health concerns related to the presence of toxic levels of heavy metals.
    Matched MeSH terms: Spectrophotometry, Atomic/methods*
  2. Murtadha S. Al-Nafiey, Mohammad S. Jaafar, Sabar Bauk
    Sains Malaysiana, 2014;43(2):227-231.
    Radon and toxic elements (Pb, Cd, Co, Cu, Cr, Zn and Ni) were measured in different water samples in Cameron Highlands, Pahang. RAD7 and rad H20 were used to estimate the radon concentration. The average values for radon concentration were found to vary from a minimum of 0.21 Bq/L to a maximum of 0.297 Bq/L. Heavy metals concentration were measured using an atomic absorption spectrometer. The mean concentrations of Pb, Cd, Co, Ni, Cu, Zn and Cr were 0.07, 0.009, 0.009, 0.043, 0.076, 0.079 mg/L and ND, respectively. Comparing the results with the literature, shows that the concentrations obtained were within the allowed limits of the agricultural and domestic use.
    Matched MeSH terms: Spectrophotometry, Atomic
  3. Shantakumari Rajan, Nur Safiyyah Ishak
    Sains Malaysiana, 2017;46:1825-1830.
    The concentrations of the heavy metal in Pacific white shrimp (Litopenaeus vannamei) purchased from the local wet markets throughout the state of Selangor were investigated using flame atomic absorption spectrometry. The order of the heavy metal concentrations were Zn>Cu>Pb>Cd, whereby the metal concentrations in most samples exceeded the limits of the Malaysian Food Regulation, 1985 and the guidelines set by the Food and Agriculture Organisation (1983). A health risk analysis based on the mean target hazard quotient (THQ) yielded values <1 for all metals for average and maximal consumers. The total THQ (tTHQ) which measures the aggregated risk due to heavy metal uptake via the ingestion of L. vannamei was 0.124 and 0.372 for average and maximal consumers, respectively. This suggests that although the metal concentrations are exceeding the limit, there is no calculated significant risk from metal toxicity by the consumption of shrimp.
    Matched MeSH terms: Spectrophotometry, Atomic
  4. Wbin-Wan-Ibrahim WA, Mirza EH, Akbar Ali SF
    Pak J Pharm Sci, 2013 Jul;26(4):823-6.
    PMID: 23811465
    Heavy metals in cigarette tobacco such as iron may cause a serious damage on human health. Surveys showed that the accumulation of certain toxic heavy metals like cadmium, mercury, iron is very often due to the effect of smoking. This work involved 15 volunteers in two randomly divided groups having the habit of cigarette smoking over 15 cigarettes / day. Concentration level of iron in blood and urine before and after treatment using the herbal medicine, widely used in Europe, is analyzed. Determination of Iron concentration in blood and urine was calculated by Inductively Coupled Plasma-Atomic Emission Spectrometry (ICP-AES) according to the procedure DIN EN ISO 11885 ("E22" from April 1998). The analysis shows that the concentration of iron in blood and urine samples in both groups increased in some volunteers instead of decrease. The independent T-test shows that the mean of iron concentration in the group A and group B had no significant difference (p>0.05). The results suggested that the herbal medicine under test does not have significant influence on reduction of iron concentration levels.
    Matched MeSH terms: Spectrophotometry, Atomic
  5. Nor Azah Yusof, Zainab Omar
    MyJurnal
    In this study, a simple, selective and sensitive method, for spectrophotometric determination of As(III) with gallocyanine as the sensitive reagent was developed. The wavelength of an analytical measurement, for the determination of As (III), using gallocyanine was at 630 nm with an optimum response at pH 2. The RSD for the reproducibility of 100 ppm As (III) was 2.3%. The LOD was 0.04 ppm with linear dynamic range in As(III) concentration of 0.2 - 1.5 ppm. The developed method has been validated against Atomic Absorption Spectrophotometry (AAS). The interference study of several metal ions was carried out and it revealed that that Mn (II) ion was interfered the most.
    Matched MeSH terms: Spectrophotometry, Atomic
  6. Sahibin Abd. Rahim, Wan Mohd. Razi Idris, Zulfahmi Ali Rahman, Kadderi Md. Desa, Tukimat Lihan, Azman Hashim, et al.
    This study was carried out at an ultrabasic area, Selaru (S1 & S2) dan Felda Rokan Barat (S3), Kuala Pilah, Negeri Sembilan. Eighteen samples of plant and their substrates were collected from study area. The purpose of this study was to determine heavy metal such as Ni, Cr, Mn, Co, Fe and Zn contents in soils and different parts of the plant, such as leaf, stem, root and fruit. Biologal Absorption Coefficient (BAC) of the plant was obtained by calculation. Heavy metals content in the plant were extracted by digestion method whereas in soil the heavy metals were extracted by sequential extraction. Heavy metals content in soil and plant extract was determined using Flame Atomic Absorption Spectrophotometer. It was found that heavy metal concentrations in soil substrate for mengkudu (Morinda citrifolia) were high for Fe followed by Cr, Ni, Mn, Zn and Co with average concentration of 1208.5, 583.4, 352.4, 352.4, 70.7 and 53.6 mg.kg-1, respectively. Available Mn and Zn concentrations were higher than the other heavy metals in term of percentage. Fe and Mn were dominant in all parts of plants however in terms of BAC average, Co showed the highest enrichment value in all parts of the plants.
    Matched MeSH terms: Spectrophotometry, Atomic
  7. Ajab H, Yaqub A, Malik SA, Junaid M, Yasmeen S, Abdullah MA
    ScientificWorldJournal, 2014;2014:413614.
    PMID: 24672317 DOI: 10.1155/2014/413614
    In this study, concentrations of Cd, Ni, Pb, and Cr were determined in tobacco, tobacco smoke-condensate, and cigarette ash for selected brands used in Pakistan. Smoking apparatus was designed for metal extraction from cigarette smoke. Samples were digested through microwave digester and then analyzed by flame atomic absorption spectrophotometer (FAAS). Higher concentration of Ni was detected in imported brands than the counterparts in the local brands. Pb levels were however higher in local brands while significant concentration of Cd was observed in both brands. For Cr, the level in tobacco of local brands was higher than their emitted smoke, whereas imported brands showed higher level in smoke than in tobacco. The cigarette ash retained 65 to 75% of the metal and about 25 to 30% went into the body. While this study revealed the serious requirement to standardize the manufacturing of tobacco products, more importantly is the urgent need for stronger enforcements to put in place to alert the general population about the hazardous effects of cigarettes and the health risks associated with these toxic metals.
    Matched MeSH terms: Spectrophotometry, Atomic
  8. Khairiah J, Lim KH, Ahmad-Mahir R, Ismail BS
    Bull Environ Contam Toxicol, 2006 Oct;77(4):608-15.
    PMID: 17123022 DOI: 10.1007/s00128-006-1106-8
    Matched MeSH terms: Spectrophotometry, Atomic
  9. Ahmad M, Narayanaswamy R
    Talanta, 1995 Sep;42(9):1337-44.
    PMID: 18966361
    Chrome azurol S immobilised on XAD-2 has been used in this study as a reagent phase for the development of an optical fibre Al(III) sensor. Using a kinetic approach, this sensor was able to give a linear response in the Al(III) concentration range of 1.3 x 10(-5)-2.0 x 10(-4) M with a limit of detection of 1.0 x 10(-4) M. The optimum responses were obtained at pH 6.0 and when the solution was stirred. The sensor response was found to have a repeatability and reproducibility of 1.6% and 5.8%, respectively. The results obtained for Al(III) determination in aqueous sample were in good agreement with those obtained using graphite furnace-atomic absorption spectrometry.
    Matched MeSH terms: Spectrophotometry, Atomic
  10. Huat LH, Zakariya D, Eng KH
    Arch. Environ. Health, 1983 7 1;38(4):205-9.
    PMID: 6614999
    This study was conducted to determine lead concentrations in breast milk among urban and rural mothers in Malaysia, and to determine if lead absorption among urban maternal populations in Malaysia poses a potential health hazard to infants through breastfeeding. Milk samples, which were collected from 89 urban and 91 rural mothers, were analyzed by flameless atomic absorption spectrophotometry. The mean lead level in urban samples was 0.0253 microgram/ml, which was significantly higher than that of the rural samples (0.0211 microgram/ml). The estimated daily lead intake of breast-fed infants in Malaysia was well below proposed tolerable levels. There also appeared to be no specific pattern in the milk lead levels at different periods of lactation. The significance of the higher milk lead concentrations in urban mothers is also discussed.
    Matched MeSH terms: Spectrophotometry, Atomic
  11. Wong MK, Koh LL
    Biol Trace Elem Res, 1986 Aug;10(2):91-7.
    PMID: 24254355 DOI: 10.1007/BF02795561
    Ninety-nine samples of common Chinese medicines were purchased from Chinese medical shops in Singapore and Malaysia and analyzed for mercury, lead, copper, cadmium, cobalt, iron, and nickel. The majority of these medicines were manufactured in China, Hong Kong, and Malaysia. A few of them were of Singapore and Taiwan origin. Atomic absorption method (both flame and flameless) was used for the analyses. Mercury was found to be present in high concentrations in several of the medicines that were for oral consumption.
    Matched MeSH terms: Spectrophotometry, Atomic
  12. Mohammed A. Jasim, Mohd Sofian-azirun, Yusoff, Motior Rahman M
    Sains Malaysiana, 2016;45:119-127.
    In this paper we have studied the acute toxicity effect of Hg on hybrid tilapia (Oreochromis niloticus). For this, the tissues of tilapia have been digested by means of acids in microwave oven and was analyzed by flameless atomic absorption spectrophotometer (FAAS). We have identified that the levels of Hg varied significantly in different tissues and the metal concentration was in the following order: liver > gills > muscles; of which the maximum level recorded for Hg was 0.799 mg/kg. We have also observed the alterations towards histopathological aspects in the gills and liver of treated fishes were studied using light and electron microscopy, subjected to the exposure of Hg for 24 h and furthermore we have also noticed the extent of the increased alterations during the 96 h of exposure to median lethal concentration LC50 (0.3 mg/L) a severe disorganization of epithelial cells and modifications of the structure of the secondary lamellae. Moreover the severity has also found to increase to sub-lethal concentration (0.03 mgHg/L) in 21 days of exposure; Liver was slightly affected by the contamination of Hg. Ultimately, histopathology is considered as a sensitive technique of bioaccumulation and for the observing the potential damage from Hg exposure.
    Matched MeSH terms: Spectrophotometry, Atomic
  13. Palihakkara CR, Dassanayake S, Jayawardena C, Senanayake IP
    J Health Pollut, 2018 Mar;8(17):14-19.
    PMID: 30524845 DOI: 10.5696/2156-9614-8.17.14
    Background: Acid mine drainage (AMD) is a major environmental impact associated with the mining industry. Elevated acidic conditions resulting from the discharge of AMD into the surrounding environment can cause heavy metals to dissolve and transport through water streams and accumulate in the aquatic environment, posing a risk to the health of living organisms. There have been several novel approaches in the remediation of AMD involving passive treatment techniques. The constructed treatment wetland approach is a passive remediation option that has proven to be a cost effective and long-lasting solution in abating toxic pollutant concentrations.

    Objectives: The present study investigates the applicability of water hyacinth (Eichhornia crassipes), a tropical aquatic plant with reported heavy metal hyper-accumulation in microcosm floating wetland treatment systems designed to remediate AMD with copper (Cu) and cadmium (Cd) concentrations exceeding threshold limits.

    Methods: Twelve water hyacinth samples were prepared with varying concentrations of Cu (1 mg/L, 2 mg/L, 4 mg/L) and Cd (0.005 mg/L, 0.01 mg/L, 0.02 mg/L). Water samples of 5 ml each were collected from each sample at 24-hour intervals for analysis with an atomic absorption spectrometer.

    Results: Plant growth varied according to Cu and Cd concentrations and no plants survived for more than 14 days. There was a significant discrepancy in the rate at which the Cd concentrations abated. The rate of reduction was rapid for higher concentrations and after 24 hours a substantial reduction was achieved. There was a reduction in Cu concentration after the first 24-hour period, and after the next 24-hour period the concentrations were again elevated in the samples at initial concentrations of 2 mg/L and A4 mg/L. 4 mg/L Cu concentration was shown to be toxic to the plants, as they had low accumulations and rapid dying was evident.

    Conclusions: Water hyacinth has the capability to reduce both Cu and Cd concentrations, except at an initial concentration of 4 mg/L of Cu, which was toxic to the plants.

    Competing Interests: The authors declare no competing financial interests.

    Matched MeSH terms: Spectrophotometry, Atomic
  14. Ang HH, Lee KL
    Food Chem Toxicol, 2006 Aug;44(8):1245-50.
    PMID: 16567029 DOI: 10.1016/j.fct.2006.01.014
    The DCA (Drug Control Authority), Malaysia has implemented the phase three registration of traditional medicines on 1 January 1992. As such, a total of 100 products in various pharmaceutical dosage forms of a herbal preparation found in Malaysia, containing tongkat Ali hitam, either single or combined preparations, were analyzed for the presence of a heavy toxic metal, mercury, using atomic absorption spectrophotometer, after performing a simple random sampling to enable each sample an equal chance of being selected in an unbiased manner. Results showed that 26% of these products possessed 0.53-2.35 ppm of mercury, and therefore, do not comply with the quality requirement for traditional medicines in Malaysia. The quality requirement for traditional medicines in Malaysia is not exceeding 0.5 ppm for mercury. Out of these 26 products, four products have already registered with the DCA, Malaysia whilst the rest, however, have not registered with the DCA, Malaysia.
    Matched MeSH terms: Spectrophotometry, Atomic
  15. Lui JL, Tong SL, Teh SK
    Ann Dent, 1994;1(1):1-4.
    MyJurnal
    The mercury controversy related to dental amalgam is still continuing. In Malaysia, part of, this controversy has been attributed to a recently - introduced dental amalgam claimed to be non-mercury releasing and causing no mercury toxicity. The purpose of this study was to investigate whether this amalgam, Composil, was indeed non-mercury releasing. Six specimens each of Composil and a control (GS-80) were incubated at 3TC in deionised-distilled water. The daily mercury release was determined over a four-week study period using the stationary cold-vapour atomic absorption spectrometric method. The mean mercury release of Composil was 30.9 Ilg/cm2/ 24hr whilst that of GS-80 was 0.9 Ilg/cm2124hr and the difference was found to be highly significant (P < 0.00l). Results of this study therefore did not substantiate the manufacturer's claim. The release of mercury from amalgam restorations and their implications in clinical practice were also discussed.
    Matched MeSH terms: Spectrophotometry, Atomic
  16. Zailina, H., Junidah, R., Jamal Hisham, H.
    MyJurnal
    Blood lead concentration and 6»aminolevulinic acid in urine were used as indicator for lead exposure among school children in an industrial area south of the peninsular Malaysia. A group of 1 00 Malay children which consist of 48 boys and 52 girb with the age range of 61/2 to 81/2 years from a primary school were selected as chiMren. Blood samples were collected and analyzed with Graphite Furnace Atomic Absorption Spectrophotometer. The urine 6-aminolevulinic acid concentrations were measured with UV/VIS Spectrophotometer. The mean blood lead was 3.75ug/dl. Based on the biological index, 76% of the children are in the “normal range" (
    Matched MeSH terms: Spectrophotometry, Atomic
  17. Shamsul, B.S., Zakirah, M.
    MyJurnal
    The main objective of this study is to determine the association between respirable hexavalent chromium compounds with urinary β2-microglobulin levels among welders in an automotive components manufacturing plant. 49 welders and 39 workers involved in stamping process were selected as the exposed and the comparative group. β2-microglobulin is a protein renal tubular dysfunction marker that can indicate renal dysfunction caused by heavy metal. Air samples of worker’s breathing zone were collected using personal air sampling pump and filter papers. Filter papers were then diluted and analysed with Atomic Absorption Spectrophotometry (AAS). Workers’ urine samples were collected at the end of 8-hour work shift and analysed with β2-microglobulin ELISA Kit (IBL-Hamburg) and a microtiter reader. Meanwhile, creatinine levels were analysed with creatinine test strips and Reflotron®. A mean concentration of respirable hexavalent chromium compounds in air for the exposed group was 0.135 ± 0.043μg/m3 while for the non-exposed group was 0.124 ± 0.029μg/m3. The mean level of urinary β2-microglobulin per creatinine for the exposed group was 84.996 ± 39.246μg/g while that of the comparative group was 61.365 ± 21.609μg/g. The concentrations of respirable hexavalent chromium compounds were higher in the exposed group compared to the comparative group (Z=-2.444, p=0.015). β2-microglobulin level was also higher in the exposed group compared to the non-exposed group (t=3.821, p=
    Matched MeSH terms: Spectrophotometry, Atomic
  18. Shamsul, B.S., How Pai, S.
    MyJurnal
    Homocysteine could be a mechanism that underlies the effects of lead on cardiovascular system. This study aims to identify the relationship between lead exposure and homocysteine levels among workers. A comparative cross-sectional study was carried out on 80 workers of an automotive components manufacturing factory; that comprised of 40 exposed workers and 40 non-exposed workers. Blood samples of respondents were taken by fingerprick. The blood samples were analyzed for blood lead concentration by using Atomic Absorption Spectrometry Graphite Furnace Model GBC 908AA. Besides that, ELISA Kit was used to show the homocysteine level among the respondents. Questionnaires were used to obtain demography information of respondents. Results from the statistical analysis showed that the mean blood lead concentration for exposed respondents was 5.53±4.74 μg/dL and 3.53±2.81 μg/dL for the comparative respondents. Mann-Whitney U test showed that there was no significance difference between the mean blood lead concentration of the exposed and comparative group (z=-1.178; p=0.075). The blood lead concentration ranged 0.68-17.95 among the exposed group and with a range of 0.084-11.96 for the comparative group. The mean homocysteine level (μmol/L) was 32.48±2.481μmol/L for the exposed group and 16.50±4.0960 μmol/L for the comparative group. There was a significant difference in homocysteine level (μmol/L) between the exposed (32.48±2.481) and comparative (16.50±4.0959) groups (z = -7.699, p
    Matched MeSH terms: Spectrophotometry, Atomic
  19. Abbas F.M.A., Saifullah, R., Azhar, M.E.
    MyJurnal
    Cavendish (Musa paradisiaca L, cv cavendshii) and Dream (Musa acuminata colla. AAA, cv ‘Berangan’) banana flours were prepared from ripe fruits collected from eleven markets located in Penang, Malaysia. The mineral composition (Na, K, Ca, Mg, Cu, Fe, Mn, Zn) of the flour were analyzed by atomic absorption spectrophotometer and the data obtained were analyzed using logistic regression model. Ripe banana flours were rich source of K and a fair source of other minerals, however logistic regression model identified Mg as an indicator to discriminate between the two types of banana flour affording 100 % correct assignation. Based on this result, mineral analysis may be suggested as a method to authenticate ripe banana flour. This study also presents the usefulness of logistic regression technique for analysis and interpretation of complex data.
    Matched MeSH terms: Spectrophotometry, Atomic
  20. Tan, Y.P., Wong, Y.C.
    MyJurnal
    Bismuth chromium solid solutions, with a general formula Bi6-xCr2Oδ, where -1 ≤ x ≤ 2, were successfully synthesized via the conventional solid state method. The phases of the synthesized samples were determined by X-ray diffraction (XRD) analysis. The properties of single-phase compounds were characterized by using differential thermal analysis (DTA), thermal gravimetric analysis (TGA), AC impedance spectroscopy, and inductively coupled plasma-atomic emission spectroscopy (ICP-AES). The occurrence of phase transitions was confirmed by DTA and TGA, where a thermal event was observed by DTA at around 800oC. In addition, TGA studies also showed that there was a weight loss at around 800oC. Elemental analysis of Bi6Cr2O15 and its solid solutions by ICP-AES showed a good agreement between the expected value and the experimental value on the compositions, with no evidence of any systematic deviation from stoichiometric. Electrical properties of Bi6Cr2O15 and its solid solutions were investigated by using AC impedance spectroscopy from 300oC to 650oC. Ionic conductivity increased with the increasing temperature and bismuth content, and the best ionic conductivity was observed for Bi7Cr2O16.5. The activation energy (Ea) of Bi6Cr2O15 and its solid solutions were in the range of 1.22-1.32 eV.
    Matched MeSH terms: Spectrophotometry, Atomic
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