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Estrogen receptor modulatory effects of germinated brown rice bioactives in the uterus of rats through the regulation of estrogen-induced genes

Muhammad SI 1 , Maznah I , Mahmud RB , Saeed MI , Imam MU , Ishaka A

Affiliations 

  • 1 Laboratory of Molecular Biomedicine, Institute of Bioscience, Universiti Putra Malaysia, Selangor, Malaysia ; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine Usmanu, Danfodiyo University Sokoto, Sokoto, Nigeria
Drug Des Devel Ther, 2013;7:1409-20.
PMID: 24324328 DOI: 10.2147/DDDT.S50861

Abstract

The expression of genes regulated by estrogen in the uterus was studied in ovariectomized (OVX) rats treated with germinated brown rice (GBR) bioactives, and compared to Remifemin or estrogen at different doses to identify the regulation of these genes in the uterus and their molecular mechanisms.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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