CYP2C19 and PON1 polymorphisms regulating clopidogrel bioactivation in Chinese, Malay and Indian subjects

Chan MY , Tan K , Tan HC , Huan PT , Li B , Phua QH Show all authors , Lee HK , Lee CH , Low A , Becker RC , Ong WC , Richards MA , Salim A , Tai ES , Koay E
Pharmacogenomics, 2012 Apr;13(5):533-42.
PMID: 22462746 DOI: 10.2217/pgs.12.24

Abstract

AIM, MATERIALS & METHODS: We investigated the functional significance of CYP2C19*2, *3, *17 and PON1 Q192R SNPs in 89 consecutive Asian patients on clopidogrel treatment and the prevalence of functionally significant polymorphisms among 300 Chinese, Malays and Asian Indians.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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