Symptom Prevalence and the Negative Emotional States in End-Stage Renal Disease Patients with or without Renal Replacement Therapy: A Cross-Sectional Analysis

Wan Zukiman WZH; Yaakup H; Zakaria NF; Shah SAB

doi:10.1089/jpm.2016.0450

Symptom Prevalence and the Negative Emotional States in End-Stage Renal Disease Patients with or without Renal Replacement Therapy: A Cross-Sectional Analysis

Wan Zukiman WZH ¹ , Yaakup H ¹ , Zakaria NF ² , Shah SAB ³

Affiliations

¹ 1 Department of Medicine, Universiti Kebangsaan Malaysia Medical Centre , Kuala Lumpur, Malaysia
² 2 Department of Medicine, Medical and Health Science Faculty, University Putra Malaysia , Selangor, Malaysia
³ 3 Department of Community Medicine, Universiti Kebangsaan Malaysia Medical Centre, UKM Medical Molecular Biology Institute (UMBI) , Kuala Lumpur, Malaysia

J Palliat Med, 2017 10;20(10):1127-1134.

PMID: 28537462 DOI: 10.1089/jpm.2016.0450

Abstract

BACKGROUND: Limited comparative data are available on the symptom severity and burden of dialyzed versus nondialyzed end-stage renal disease (ESRD) patients and their association with negative emotional states.

OBJECTIVE: To investigate the prevalence of symptom burden and severity of ESRD patients and correlate the findings with their psychological status.

METHODS: This was a cross-sectional study of dialyzed (N = 87) and nondialyzed (N = 100) patients. The symptom burden and severity were determined using the Dialysis Symptom Index (DSI) and the psychological assessment using Depression Anxiety Stress Scale 21 (DASS-21).

RESULTS: Symptom severity evaluated using the DSI was comparable in both groups with fatigue as the most common symptom (n = 141, 75.4%), followed by sleep-related, sexual dysfunction, and dry skin problems. The symptom burden for worrying, dry skin and mouth, decreased appetite, numbness, and leg swelling were significant in not dialyzed group (p

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.